KR20210044247A - Lcp-1 양성 암을 대상으로 하는 microrna 기반 치료 - Google Patents
Lcp-1 양성 암을 대상으로 하는 microrna 기반 치료 Download PDFInfo
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1135—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against oncogenes or tumor suppressor genes
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- C—CHEMISTRY; METALLURGY
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering N.A.
- C12N2310/141—MicroRNAs, miRNAs
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
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- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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| EP18020374.7 | 2018-08-08 | ||
| EP18020374 | 2018-08-08 | ||
| PCT/EP2019/071341 WO2020030750A1 (en) | 2018-08-08 | 2019-08-08 | Microrna-based therapy targeted against lcp-1 positive cancers |
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| CN111643527B (zh) * | 2020-07-22 | 2020-12-29 | 广东赛尔生物科技有限公司 | 转基因干细胞外泌体在制备药物或美白化妆品中的用途 |
| CN112294960B (zh) * | 2020-10-30 | 2022-02-08 | 浙江大学 | 微小分子RNA-30b-5p作为靶分子的用途 |
| WO2022154601A1 (ko) * | 2021-01-14 | 2022-07-21 | 연세대학교 산학협력단 | 신규 췌장암 바이오마커 및 이의 용도 |
| CN114350800B (zh) * | 2021-12-29 | 2024-03-19 | 中南大学湘雅医院 | Sphk1在制备pd-l1/pd-1单抗肿瘤免疫治疗药物中的应用 |
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| WO2013048734A1 (en) * | 2011-09-28 | 2013-04-04 | Tufts Medical Center, Inc. | Treatment and prevention of cardiovascular disease with cell derived lipid vesicles, microvesicles and exosomes |
| EP4074834A1 (en) * | 2012-11-26 | 2022-10-19 | ModernaTX, Inc. | Terminally modified rna |
| CA2900897A1 (en) * | 2013-02-12 | 2014-08-21 | Reneuron Limited | Method of producing microparticles |
| WO2016166600A1 (en) * | 2015-04-15 | 2016-10-20 | Trojantec Technologies Ltd | Delivery of microrna using mesenchymal stem cell microparticles |
| WO2017005773A1 (en) * | 2015-07-07 | 2017-01-12 | Universite de Bordeaux | Use of catenin- beta 1-targeting micrornas for treating liver cancer |
| WO2018058064A1 (en) * | 2016-09-23 | 2018-03-29 | Casebia Therapeutics Limited Liability Partnership | Compositions and methods for gene editing |
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- 2019-08-08 KR KR1020217006923A patent/KR20210044247A/ko not_active Application Discontinuation
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- 2019-08-08 WO PCT/EP2019/071341 patent/WO2020030750A1/en active Search and Examination
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| MX2021001517A (es) | 2021-04-19 |
| EA202190474A1 (ru) | 2021-04-15 |
| BR112021002321A2 (pt) | 2021-05-11 |
| EP3833760B1 (en) | 2024-07-17 |
| AU2019319623A1 (en) | 2021-02-25 |
| CA3108172A1 (en) | 2020-02-13 |
| WO2020030750A1 (en) | 2020-02-13 |
| SG11202101069SA (en) | 2021-03-30 |
| EP3833760A1 (en) | 2021-06-16 |
| US20210369760A1 (en) | 2021-12-02 |
| CN112567034A (zh) | 2021-03-26 |
| IL280622A (en) | 2021-03-25 |
| BR112021002321B1 (pt) | 2023-11-28 |
| JP2021533822A (ja) | 2021-12-09 |
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