KR20200065521A - Feminine Cleanser Composition Comprising Natural Antimicrobial Agents - Google Patents

Feminine Cleanser Composition Comprising Natural Antimicrobial Agents Download PDF

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KR20200065521A
KR20200065521A KR1020180152066A KR20180152066A KR20200065521A KR 20200065521 A KR20200065521 A KR 20200065521A KR 1020180152066 A KR1020180152066 A KR 1020180152066A KR 20180152066 A KR20180152066 A KR 20180152066A KR 20200065521 A KR20200065521 A KR 20200065521A
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green tea
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김동현
이지영
김가영
이재선
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호서대학교 산학협력단
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/82Theaceae (Tea family), e.g. camellia
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    • A61K36/88Liliopsida (monocotyledons)
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    • AHUMAN NECESSITIES
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    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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Abstract

The present invention relates to a feminine cleanser composition containing a mixed extract of Scutellaria baicalensis, Punica granatum, Anemarrhena asphodeloides, green tea, and Schisandra chinensis. The feminine cleanser composition according to the present invention has high safety to the human body by using a natural product, and has an excellent antibacterial effect, thereby being effective for maintaining cleanliness of women and preventing women′s diseases.

Description

천연 항균제를 포함하는 여성청결제 조성물{Feminine Cleanser Composition Comprising Natural Antimicrobial Agents}Feminine Cleanser Composition Comprising Natural Antimicrobial Agents

본 발명은 황금, 석류피, 지모, 녹차 및 오미자의 혼합 추출물을 포함하는 여성청결제 조성물에 관한 것이다.The present invention relates to a feminine cleanser composition comprising a mixed extract of golden, pomegranate, jimo, green tea, and omija.

여성의 비뇨생식기계는 자궁, 질, 외음부, 요도 등을 포함하며, 해부생리학적, 기능적 특성상 외부로부터의 감염에 노출되기 쉽다. 예를 들어, 질은 양분이 풍부하여 인체 깊숙히 위치하고 있으므로, 온도와 습도가 높기 때문에 질염의 주원인인 세균이나 곰팡이를 포함한 여러 균주들의 침범이 용이하여 여러 질환이 발생할 가능성이 크다. 그러므로 항상 질은 청결히 유지하고 외부로부터 세균감염에 노출되지 않도록 유의하는 것이 바람직하다.The female genitourinary system includes the uterus, vagina, vulva, urethra, and is susceptible to external infections due to anatomical physiological and functional characteristics. For example, since the vagina is rich in nutrients and is located deep in the human body, the temperature and humidity are high, so it is easy to invade various strains, including bacteria and fungi, which are the main causes of vaginitis, and thus, it is highly likely to cause various diseases. Therefore, it is always desirable to keep the vagina clean and be careful not to be exposed to bacterial infection from the outside.

또한, 여성 비뇨생식기계에는 비뇨생식기계 pH를 약산성으로 유지하여 주는 유산간균이 존재하여 유해한 세균의 번식을 막아 주는 역할을 하지만, 물리적 손상, 스트레스 및 호르몬 불균형 외에도 청결하지 않은 비뇨생식기계 환경, 성관계에 따른 세균성 질환 혹은 성병 등에 의해 여성 비뇨생식기계 관련 질환이 발생되기 쉬우며, 의료기구를 체내에 도입할 때 또는 출산 시 발생하는 점막의 상처는 병원균의 감염의 기회를 높이고, 염증을 유발할 수 있다.In addition, the female genitourinary system has a lactic acid bacterium that maintains the pH of the genitourinary system in a weakly acidic role, which prevents the growth of harmful bacteria, but in addition to physical damage, stress, and hormonal imbalance, the unclean genitourinary system environment, bacterial according to sex It is easy to develop diseases related to the genitourinary system of women due to diseases or sexually transmitted diseases, and wounds of mucous membranes that occur when a medical device is introduced into the body or during childbirth can increase the chance of infection of pathogens and cause inflammation.

이러한 비뇨생식기계 염증은 부인과를 찾아오는 환자들의 가장 흔한 질환 중의 하나이며, 세균성에서부터 기생충, 바이러스에 이르기까지 매우 다양하다. 이들 환자들은 소양감 및 심한 염증과 악취를 동반하게 되는데, 특히 인유두종 바이러스의 감염은 자궁경부암과 매우 밀접한 관계가 있어 세심한 주의가 필요하다. 그러므로, 이에 따른 적절한 예방, 진단과 치료로서 치명적 합병증을 감소시키는 것은 매우 중요하며, 이와 같은 여성질환을 예방하고 불쾌한 냄새를 제거하기 위해서 여성청결제를 사용하는 경우가 많다.This genitourinary system inflammation is one of the most common diseases of gynecological patients, and can range from bacterial to parasitic to viral. These patients are accompanied by a feeling of pruritus and severe inflammation and odor. In particular, infection of the human papilloma virus is very closely related to cervical cancer, so it needs attention. Therefore, it is very important to reduce fatal complications as appropriate prevention, diagnosis, and treatment, and in many cases, female cleansers are used to prevent such female diseases and remove unpleasant odors.

질염을 예방을 위해 사용되는 국부용 세정제는 지방산류 또는 증류된 라우릴알콜 등을 설폰화하고 완화제, 점증제, 영양제, 기포제, 유기살균제 등을 함유된 것이나, 또는 세정력을 지닌 계면 활성제 및 의약품으로서의 포비돈-요오드를 주성분으로 하는 것을 예로 들 수 있다. 그러나, 화학적 여성청결제의 주성분인 요오드는 과민 증상이나 점막 손상에 의한 소양감, 작열감, 피부 궤양, 접촉성 피부염 등을 일으킬 우려가 있으며, 질내 무기 요오드 또는 혈중 총 요오드치가 상승하여 갑상선 기능 저하증을 유발할 수 있는 것으로 알려져 있다. Local cleaners used to prevent vaginitis are sulfonated fatty acids or distilled lauryl alcohol and contain emollients, thickeners, nutrients, foaming agents, organic fungicides, or as surfactants and pharmaceuticals with cleaning power Examples include povidone-iodine as a main component. However, iodine, the main component of chemical cleansing agents, may cause irritation or irritation due to mucosal damage, burning sensation, skin ulcers, contact dermatitis, etc.Inorganic iodine in the vagina or total iodine in the blood may increase, leading to hypothyroidism. It is said to be.

여성청결제는 민감한 점막 부위에 사용하므로, 화학적 합성물질의 사용은 안전하지 못하며, 이에, 종래 알려진 여성용 청결제에 비하여 보다 효과가 우수하고 안전한 물질로서 천연물을 이용한 새로운 여성청결제 조성물의 개발이 절실히 요구되고 있는 실정이다.Since female cleansing agents are used in sensitive mucosal areas, the use of chemical synthetic materials is not safe, and thus, the development of new female cleansing compositions using natural products as a more effective and safer material than conventionally known female cleansers is urgently required. This is true.

대한민국 등록 특허 제10-1651530호Republic of Korea Registered Patent No. 10-1651530

본 발명의 일 목적은 황금, 석류피, 지모, 녹차 및 오미자의 혼합 추출물을 포함하는 여성청결제 조성물을 제공하는 것이다.One object of the present invention is to provide a feminine cleanser composition comprising a mixed extract of golden, pomegranate, jimo, green tea, and Omija.

상기 목적을 달성하기 위하여 본 발명의 일 양상은 황금, 석류피, 지모, 녹차 및 오미자의 혼합 추출물을 포함하는 여성청결제 조성물을 제공한다.In order to achieve the above object, an aspect of the present invention provides a feminine cleanser composition comprising a mixed extract of golden, pomegranate, jimo, green tea, and omija.

구체적으로, 본 발명은 인체에 유익한 황금, 석류피, 지모, 녹차 및 오미자로부터 농축액을 추출하고, 추출된 농축액과 점증제, 보습제 및 산도 조절제와 혼합하여 제조하여, 화학물질에 의한 과민 반응 등을 방지할 수 있는 천연물 추출물을 이용한 여성청결제 조성물에 관한 것이다. Specifically, the present invention extracts concentrates from golden, pomegranate, zymote, green tea and Omija, which are beneficial to the human body, and is prepared by mixing the extracted concentrate with a thickener, a moisturizer, and an acidity regulator to prevent hypersensitivity reactions caused by chemicals. It relates to a female cleanser composition using a natural extract that can be.

황금은 해열, 이뇨, 지사, 이담 및 소염제로 이용하며 플라보노이드 성분이 포함되어 있어, 지혈, 안태의 효능이 있고, 자궁출혈 방지, 방광염, 요도염 등 항염 작용을 하는 것으로 알려져 있다. 석류피는 설사를 멎게 하고, 출혈을 방지하며, 비생리적으로 냉이 나오는 증상이나 비정상적 자궁출혈을 치료하는 효능을 갖는다. 지모는 해열 작용, 부신피질호르몬의 자극을 억제하거나, 결핵균, 이질균, 대장균 등에 항균 효과가 있다. 녹차는 비타민 C와 카테킨 성분이 다량 함유되어 있어 항산화 작용에 도움을 주는 것은 물론 항염증, 항암, 콜레스테롤 저하에 도움을 주며, 피부미용에 유익한 효과가 있다. 오미자는 항산화 성분을 포함하여 혈류 개선, 고혈압, 심혈관 질환에 효능이 있으며, 면역력을 개선하고, 간기능 개선과 피부 트러블에도 효과가 있다.Golden is used as an antipyretic, diuretic, branch, biliary tract and anti-inflammatory agent, and it contains flavonoids, so it has the effect of hemostasis, restlessness, and is known to have anti-inflammatory properties such as preventing uterine bleeding, cystitis, and urethritis. Pomegranate has the effect of stopping diarrhea, preventing bleeding, and treating non-physiologically cold symptoms or abnormal uterine bleeding. Zimo suppresses antipyretic action, stimulation of adrenal cortical hormones, or has antibacterial effects on Mycobacterium tuberculosis, dysentery and E. coli. Green tea contains a large amount of vitamin C and catechin, which not only helps with antioxidant activity, but also helps with anti-inflammatory, anti-cancer, and cholesterol reduction, and has a beneficial effect on skin beauty. Omija is effective in improving blood flow, high blood pressure, and cardiovascular diseases, including antioxidants, improving immunity, and improving liver function and skin problems.

본 명세서에서 용어 "추출물"은 황금, 석류피, 지모, 녹차 및 오미자를 적절한 추출용매로 추출하여 얻은 추출액을 의미하는 것으로, 추출처리에 의해 얻어지는 추출액, 추출액의 희석액 또는 농축액, 추출액을 건조하여 얻어지는 건조물, 이들의 조정제물 또는 정제물일 수 있으나, 이에 한정하지는 않는다. 본 발명에 따른황금, 석류피, 지모, 녹차 및 오미자의 혼합 추출물은 당업계에 공지된 일반적인 추출방법, 분리 및 정제방법을 이용하여 제조할 수 있다. 상기 추출방법으로는 열탕 추출, 열수 추출, 냉침 추출, 환류 냉각 추출 또는 초음파 추출 등의 방법을 사용할 수 있으나, 이에 한정되지 않는다.As used herein, the term "extract" refers to an extract obtained by extracting golden, pomegranate, jimo, green tea, and Omija with an appropriate extraction solvent, an extract obtained by an extraction process, a dilution or concentrate of an extract, or a dried product obtained by drying an extract , These may be a crude or purified product, but are not limited thereto. Golden, pomegranate, jimo, green tea and Omija   mixed extract according to the present invention can be prepared using general extraction methods, separation and purification methods known in the art. The extraction method may include hot water extraction, hot water extraction, cold needle extraction, reflux cooling extraction, or ultrasonic extraction, but is not limited thereto.

본 발명에 있어서, 상기 추출물은 추출용매로 추출하거나 추출용매로 추출하여 제조한 추출물에 분획용매를 가하여 분획함으로써 제조할 수 있다. 상기 추출용매는 이에 제한되지는 않으나, 물, 유기용매 또는 이들의 혼합용매 등을 사용할 수 있으며, 상기 유기용매는 탄소수 1 내지 4의 알코올이나, 에틸아세테이트 또는 아세톤 등의 극성용매, 헥산 또는 디클로로메탄의 비극성용매 또는 이들의 혼합용매를 사용할 수 있다. 또한, 바람직하게는 물, 탄소수 1 내지 4의 알코올 또는 이들의 혼합용매를 사용할 수 있으며, 상기 추출물은 에탄올 추출물인 것이 가장 바람직하다.In the present invention, the extract may be prepared by extracting with an extraction solvent or by fractionating an extract prepared by extraction with an extraction solvent by adding a fractional solvent. The extraction solvent is not limited thereto, and water, an organic solvent, or a mixed solvent thereof may be used, and the organic solvent is an alcohol having 1 to 4 carbon atoms, a polar solvent such as ethyl acetate or acetone, hexane or dichloromethane. Non-polar solvents or mixed solvents of these may be used. In addition, preferably, water, an alcohol having 1 to 4 carbon atoms or a mixed solvent thereof may be used, and the extract is most preferably an ethanol extract.

본 발명의 일 구체예에 따르면, 상기 조성물은 붉나무충영 추출물 및 쑥잎 추출물을 더 포함할 수 있다.According to an embodiment of the present invention, the composition may further include a red bark extract and wormwood leaf extract.

붉나무충영 추출물은 질염의 원인균인 칸디다균에 대한 항균 효과가 있는 것으로 알려져 있어 본 발명의 혼합 추출물에 항균 효과를 증가시킬 수 있으며, 쑥잎 추출물은 본 발명의 여성청결제 조성물에 탈취 효과를 부여한다.The red barberry extract is known to have an antibacterial effect against Candida, the causative agent of vaginitis, and can increase the antibacterial effect on the mixed extract of the present invention, and the mugwort leaf extract imparts a deodorizing effect to the female cleanser composition of the present invention.

본 발명의 일 구체예에 따르면, 상기 조성물은 자무, 락토바실러스, 나이아신아미드, 소듐히알루로네이트, 알지닌, 글리세린, 1,2-헥산디올, 베타글루칸, 히알루론산, 아데노신, 부틸렌글리콜 및 히드록시에틸셀룰로오스를 더 포함할 수 있으며, 상기 조성물은 조성물 총 중량 대비 황금, 석류피, 지모, 녹차 및 오미자의 혼합 추출물 0.5 내지 10 중량%, 붉나무충영 추출물 0.1 내지 3 중량%, 쑥잎 추출물 0.1 내지 3 중량%, 자무 0.1 내지 3 중량%, 락토바실러스 분말 0.1 내지 3 중량%, 나이아신아미드 0.1 내지 3 중량%, 소듐히알루로네이트 0.1 내지 3 중량%, 알지닌 0.5 내지 2 중량%, 글리세린 3 내지 9 중량%, 1,2-헥산디올 0.5 내지 1.5 중량%, 베타글루칸 1 내지 5 중량%, 히알루론산 3 내지 10 중량%, 아데노신 0.1 내지 1 중량%, 부틸렌글리콜 0.3 내지 3 중량% 및 히드록시에틸셀룰로오스 3 내지 25 중량%를 포함하는 것이 가장 바람직하다.According to one embodiment of the invention, the composition is jammu, lactobacillus, niacinamide, sodium hyaluronate, arginine, glycerin, 1,2-hexanediol, beta-glucan, hyaluronic acid, adenosine, butylene glycol and hydroxy The composition may further include hydroxyethyl cellulose, and the composition may contain 0.5 to 10% by weight of a mixed extract of golden, pomegranate, jimo, green tea, and Omija, 0.1 to 3% by weight of red prickly pear extract, and 0.1 to 3% of wormwood leaf extract based on the total weight of the composition. %, Jammu 0.1-3 wt%, Lactobacillus powder 0.1-3 wt%, Niacinamide 0.1-3 wt%, Sodium hyaluronate 0.1-3 wt%, Arginine 0.5-2 wt%, Glycerin 3-9 wt% , 1,2-hexanediol 0.5 to 1.5 wt%, beta glucan 1 to 5 wt%, hyaluronic acid 3 to 10 wt%, adenosine 0.1 to 1 wt%, butylene glycol 0.3 to 3 wt% and hydroxyethylcellulose 3 It is most preferred to include 25% by weight.

또한, 상기 여성청결제 조성물을 이용하여 여성청결제를 제조하는 경우, 10 내지 40 중량%의 정제수가 포함될 수 있으며, 정제수는 여성청결제 제품의 농도를 조절하고, 각 성분의 용매역할을 하는 것으로서, 상수를 증류하거나 이온교환수지를 통하여 정제한 물을 사용할 수 있다.In addition, when preparing a female cleansing agent using the female cleansing agent composition, 10 to 40% by weight of purified water may be included, and the purified water controls the concentration of the female cleansing agent product and acts as a solvent for each component. Distilled or purified water through ion exchange resin can be used.

본 발명에 따른 여성청결제는 일반적인 기능성 화장품 형태, 외용제 또는 스프레이 형태로 제조될 수 있으나, 이에 한정하지는 않는다.The female cleansing agent according to the present invention may be prepared in a general functional cosmetic form, an external preparation or a spray form, but is not limited thereto.

본 발명에 따른 여성청결제 조성물은 천연물을 사용하여 인체에 안전성이 높으며, 항균 효과가 우수하여 여성의 청결 유지 및 여성질환을 예방하는데 효과적이다.The female cleanser composition according to the present invention is effective in maintaining cleanliness of women and preventing women's diseases by using natural products and having high safety to the human body and excellent antibacterial effect.

도 1은 페이퍼디스크법을 이용하여 본 발명에 따른 혼합 추출물의 항균 효과를 확인한 결과를 나타낸다.1 shows the results of confirming the antibacterial effect of the mixed extract according to the present invention using the paper disc method.

이하 하나 이상의 구체예를 실시예를 통하여 보다 상세하게 설명한다. 그러나, 이들 실시예는 하나 이상의 구체예를 예시적으로 설명하기 위한 것으로 본 발명의 범위가 이들 실시예에 한정되는 것은 아니다.Hereinafter, one or more specific examples will be described in more detail through examples. However, these examples are intended to illustrate one or more embodiments by way of example, and the scope of the present invention is not limited to these examples.

실시예 1: 황금, 석류피, 지모, 녹차, 오미자 혼합 추출물의 제조Example 1: Preparation of golden, pomegranate, jimo, green tea, omija mixed extract

33.3%의 에탄올 또는 주정 7.2 L를 사용하여 약초시장에서 구입한 황금 405 g, 석류피 571 g, 지모 100 g, 녹차잎 141 g, 오미자 189.2 g을 넣고, 초음파 처리기(KODO, Hwaseong, Korea, 출력 1,200 W, 주파수 28 KHz)로 50℃에서 2시간 추출한 후에 95~100℃에서 3시간 열수 추출한 후, 여과하였다. 상기 여과된 추출물 100 ml를 재 여과하고, 93℃에서 감압농축하여 상기 5종 천연물의 혼합 추출물을 수득하였다.Using 33.3% of ethanol or 7.2 L of alcohol, 405 g of gold purchased from the herbal medicine market, 571 g of pomegranate, 100 g of jimo, 141 g of green tea leaves, 189.2 g of Omija, and sonicator (KODO, Hwaseong, Korea, output 1,200) W, a frequency of 28 KHz) was extracted at 50°C for 2 hours, followed by hot water extraction at 95 to 100°C for 3 hours, and then filtered. 100 ml of the filtered extract was filtered again and concentrated under reduced pressure at 93° C. to obtain a mixed extract of the above five natural products.

실시예 2: 황금, 석류피, 지모, 녹차, 오미자 혼합 추출물의 항균 실험Example 2: Antibacterial experiment of golden, pomegranate, jimo, green tea, omija mixed extract

항균 효과는 상기 실시예 1에서 제조한 혼합 추출물을 페이퍼 디스크에 적시어, 미생물을 도말한 배지위에 올려놓고 배양한 다음, 디스크 주위의 투명환(clear zone)의 크기를 측정하여 비교하였다.The antimicrobial effect was compared by soaking the mixed extract prepared in Example 1 on a paper disk, placing the microorganism on a smeared medium, and culturing it, and then measuring the size of a clear zone around the disk.

구체적으로, 실시예 1에서 제조한 혼합 추출물 50 ㎕를 페이퍼 디스크(지름 8mm, 두께 1.5mm)에 적신 다음, 실온에서 하루 동안 방치하였다. 항균력 실험을 수행할 대상 4종의 균주(Pseudomonas aeruginosa, Candida albicans, Escherichia coli, Bacillus cereus)는 각각 30℃ 또는 37℃에서 1-2일 동안 배양하여, 흡광도를 측정하고 1×104 CFU가 되도록 계산한 다음, 고체 배지(Pseudomonas aeruginosa, Escherichia coli, Bacillus cereus는 Nutrient Agar 배지, Candida albicans는 Sabrouraud Dextrose Agar 배지) 위에 상기 4종의 균주를 각각 고르게 도말하고, 37℃의 인큐베이터에서 2-3일 동안 배양하였다. 이후, 페이퍼 디스크 주변에 균이 자라지 않은 투명환의 지름을 측정함으로써 항균력을 확인하였다. Specifically, 50 μl of the mixed extract prepared in Example 1 was soaked in a paper disk (diameter 8 mm, thickness 1.5 mm), and then left at room temperature for one day. The four strains (Pseudomonas aeruginosa, Candida albicans, Escherichia coli, Bacillus cereus) to be tested for antibacterial activity were incubated for 1-2 days at 30°C or 37°C, respectively, to measure absorbance and to be 1×10 4 CFU. After calculation, each of the above four strains was evenly spread on a solid medium (Pseudomonas aeruginosa, Escherichia coli, Nutrient Agar medium for Bacillus cereus, Sabrouraud Dextrose Agar medium for Candida albicans), respectively, at 37°C. Incubate for 2-3 days in an incubator . Thereafter, antibacterial activity was confirmed by measuring the diameter of a transparent ring in which bacteria did not grow around the paper disc.

도 1에서, 1은 30% 에탄올, 2는 60% 에탄올을 첨가한 페이퍼디스크이며, 3에서 확인된 투명환의 크기는 각각 Pseudomonas aeruginosa - 2.4mm, Candida albicans - 1.4mm, Escherichia coli - 2.6,mm, Bacillus cereus - 2.7mm 로 나타났다. 도 1에서 확인한 바와 같이, 5종의 천연물이 포함된 혼합 추출물은 각종 유해균에 우수한 항균 효과를 나타냄을 확인하였다.In FIG. 1, 1 is 30% ethanol, 2 is 60% ethanol, and the paper disk is added, and the sizes of the transparent rings identified in 3 are Pseudomonas aeruginosa-2.4 mm, Candida albicans-1.4 mm, Escherichia coli-2.6, mm, respectively. Bacillus cereus-2.7mm. As shown in Figure 1, it was confirmed that the mixed extract containing five kinds of natural products shows excellent antibacterial effects on various harmful bacteria.

실시예 3: 여성청결제의 제조Example 3: Preparation of female cleansing agent

상기 실시예 2에서 확인한 각 세균에 대한 항균 효과 측정 결과로부터, 아래의 표 1에 기재된 조성을 갖는 여성청결제를 제조하였다.From the results of measuring the antibacterial effect for each bacterium identified in Example 2, a female cleansing agent having the composition shown in Table 1 below was prepared.

구체적으로, 실시예 1에서 제조한 황금, 석류피, 지모, 녹차 및 오미자의 혼합 추출물 25 중량%, 자무 1 중량%, 락토바실러스 1 중량%, 나이아신아미드 1 중량%, 소듐히알루로네이트 1 중량%, 알지닌 1.6 중량%, 글리세린 8 중량%, 1,2-헥산디올 0.5 중량%, 베타글루칸 3 중량%, 히알루론산 5 중량%, 아데노신 0.01 중량%, 부틸렌글리콜 1.5 중량% 및 히드록시에틸셀룰로오스 11 중량%, 붉나무충영 추출물 10 중량%(충영 200g을 물 1L로 추출 95~100℃에서 3시간 열수 추출한 후, 여과한 다음, 상기 여과된 추출물 100 ml를 재 여과하고, 93℃에서 감압농축하여 추출물을 수득함), 쑥잎 추출물 5 중량%(쑥잎 100g 에 물 1L 로 추출 95~100℃에서 3시간 열수 추출한 후, 여과한 다음, 상기 여과된 추출물 100 ml를 재 여과하고, 93℃에서 감압농축하여 추출물을 수득함)를 혼합하고, 하루 정도 숙성시켜 본 발명에 따른 여성청결제를 제조하였다.Specifically, the golden, pomegranate, Jimo, green tea and Omija mixed extract prepared in Example 1 25% by weight, Jammu 1% by weight, Lactobacillus 1% by weight, niacinamide 1% by weight, sodium hyaluronate 1% by weight, Arginine 1.6 wt%, glycerin 8 wt%, 1,2-hexanediol 0.5 wt%, beta glucan 3 wt%, hyaluronic acid 5 wt%, adenosine 0.01 wt%, butylene glycol 1.5 wt% and hydroxyethylcellulose 11 Weight%, 10% by weight of reddish bark extract (200g of Chungyoung extracted with 1L of water, extracted with hot water at 95~100℃ for 3 hours, filtered and then filtered, and then filtered again with 100 ml of the filtered extract and concentrated under reduced pressure at 93℃. To obtain), wormwood leaf extract 5% by weight (100 g of wormwood leaves extracted with 1 L of water for 3 hours hot water extraction at 95-100° C., filtered and then filtered again, 100 ml of the filtered extract was concentrated under reduced pressure at 93° C. The mixture was obtained) and aged for about a day to prepare a female cleansing agent according to the present invention.

여성청결제 성분표Women Cleanser Ingredients Table 1One 정제수Purified water 10~40 중량%10-40% by weight 22 자무Jammu 0.1-3 중량%0.1-3% by weight 33 락토바실러스Lactobacillus 0.1-3 중량%0.1-3% by weight 44 나이아신아마이드Niacinamide 0.1-3 중량%0.1-3% by weight 55 소듐하이알루로네이트Sodium hyaluronate 0.1-3 중량%0.1-3% by weight 66 알지닌Arginine 0.5-2 중량%0.5-2% by weight 77 붉나무충영추출물Reddish Redberry Extract 3-10 중량%3-10% by weight 88 쑥잎추출물Mugwort Leaf Extract 0.1-5 중량%0.1-5 wt% 99 황금 추출물Golden extract 0.3-10 중량%0.3-10% by weight 1010 석류피 추출물Pomegranate extract 0.3-10 중량%0.3-10% by weight 1111 지모 추출물Jimo extract 0.3-5 중량%0.3-5% by weight 1212 녹차 추출물Green tea extract 0.3-5 중량%0.3-5% by weight 1313 오미자 추출물Omija extract 0.3-5 중량%0.3-5% by weight 1414 글리세린glycerin 3-9 중량%3-9% by weight 1515 1,2-핵산디올1,2-nucleic acid diol 0.5-1.5 중량%0.5-1.5 wt% 1616 베타글루칸Beta glucan 0.3-5 중량%0.3-5% by weight 1717 히알루론산Hyaluronic acid 1-5 중량%1-5 wt% 1818 아데노신Adenosine 0.01-1 중량%0.01-1% by weight 1919 부틸렌글리콜Butylene glycol 0.3-3 중량%0.3-3 wt% 2020 하이드록시에틸셀룰로오스Hydroxyethyl cellulose 3-25 중량%3-25% by weight 합계Sum 100.0 중량%100.0 wt%

이제까지 본 발명에 대하여 그 바람직한 실시예들을 중심으로 살펴보았다. 본 발명이 속하는 기술 분야에서 통상의 지식을 가진 자는 본 발명이 본 발명의 본질적인 특성에서 벗어나지 않는 범위에서 변형된 형태로 구현될 수 있음을 이해할 수 있을 것이다. 그러므로 개시된 실시예들은 한정적인 관점이 아니라 설명적인 관점에서 고려되어야 한다. 본 발명의 범위는 전술한 설명이 아니라 특허청구범위에 나타나 있으며, 그와 동등한 범위 내에 있는 모든 차이점은 본 발명에 포함된 것으로 해석되어야 할 것이다.So far, the present invention has been focused on the preferred embodiments. Those skilled in the art to which the present invention pertains will understand that the present invention may be implemented in a modified form without departing from the essential characteristics of the present invention. Therefore, the disclosed embodiments should be considered in terms of explanation, not limitation. The scope of the present invention is shown in the claims rather than the foregoing description, and all differences within the equivalent range should be interpreted as being included in the present invention.

Claims (5)

황금, 석류피, 지모, 녹차 및 오미자의 혼합 추출물을 포함하는 여성청결제 조성물.
Feminine cleaner composition comprising a mixed extract of golden, pomegranate, jimo, green tea, and omija.
청구항 1에 있어서, 상기 추출물은 에탄올 추출물인 것인 여성청결제 조성물.
The method according to claim 1, wherein the extract is a female cleanser composition that is an ethanol extract.
청구항 1에 있어서, 상기 조성물은 붉나무충영 추출물 및 쑥잎 추출물을 더 포함하는 것인 여성청결제 조성물.
The method according to claim 1, wherein the composition is a feminine cleanser composition further comprising a red bark extract and wormwood leaf extract.
청구항 1에 있어서, 상기 조성물은 자무, 락토바실러스, 나이아신아미드, 소듐히알루로네이트, 알지닌, 글리세린, 1,2-헥산디올, 베타글루칸, 히알루론산, 아데노신, 부틸렌글리콜 및 히드록시에틸셀룰로오스를 더 포함하는 것인 여성청결제 조성물.
The method according to claim 1, wherein the composition is jammu, lactobacillus, niacinamide, sodium hyaluronate, arginine, glycerin, 1,2-hexanediol, beta glucan, hyaluronic acid, adenosine, butylene glycol and hydroxyethyl cellulose Female cleanser composition that further comprises.
청구항 1에 있어서, 상기 조성물은 조성물 총 중량 대비 황금, 석류피, 지모, 녹차 및 오미자의 혼합 추출물 0.5 내지 10 중량%, 붉나무충영 추출물 0.1 내지 3 중량%, 쑥잎 추출물 0.1 내지 3 중량%, 자무 0.1 내지 3 중량%, 락토바실러스 분말 0.1 내지 3 중량%, 나이아신아미드 0.1 내지 3 중량%, 소듐히알루로네이트 0.1 내지 3 중량%, 알지닌 0.5 내지 2 중량%, 글리세린 3 내지 9 중량%, 1,2-헥산디올 0.5 내지 1.5 중량%, 베타글루칸 1 내지 5 중량%, 히알루론산 3 내지 10 중량%, 아데노신 0.1 내지 1 중량%, 부틸렌글리콜 0.3 내지 3 중량% 및 히드록시에틸셀룰로오스 3 내지 25 중량%를 포함하는 것인 여성청결제 조성물.The method according to claim 1, The composition of the total weight of the composition relative to the golden, pomegranate, jimo, green tea and mixed extract of Omija 0.5 to 10% by weight, prickly pear extract 0.1 to 3% by weight, wormwood leaf extract 0.1 to 3% by weight, jammu 0.1 to 3 wt%, Lactobacillus powder 0.1-3 wt%, Niacinamide 0.1-3 wt%, Sodium hyaluronate 0.1-3 wt%, Arginine 0.5-2 wt%, Glycerin 3-9 wt%, 1,2- Hexanediol 0.5 to 1.5 wt%, beta glucan 1 to 5 wt%, hyaluronic acid 3 to 10 wt%, adenosine 0.1 to 1 wt%, butylene glycol 0.3 to 3 wt% and hydroxyethylcellulose 3 to 25 wt% Women cleanser composition that will contain.
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