KR20180059138A - composion preventing hair loss and manufacturing method thereof using Natural complex extract - Google Patents
composion preventing hair loss and manufacturing method thereof using Natural complex extract Download PDFInfo
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Abstract
Description
본 발명은 탈모예방 및 두피 개선효과가 우수한 천연복합소재 추출물을 활용한 탈모예방 조성물 및 그의 제조방법에 관한 것이다. The present invention relates to a composition for preventing hair loss and a method for producing the same, which utilizes a natural complex material extract having excellent hair loss preventing effect and scalp improving effect.
탈모방지와 발모 관련 종래 기술을 살펴보면 종래기술의 62%가 천연물을 소재로 하는 것이 주요 특징이며 천연물을 함유한 탈모예방 모발제의 천연재료로는 인삼, 상백(뽕나무), 검은콩, 검은깨, 오가피, 구기자 등이 많이 사용되고 있으며 최근에는 숯, 황토 등을 이용한 연구도 진행되고 있다. As for the conventional techniques related to the prevention of hair loss and hair growth, 62% of the prior art is characterized by using natural materials. The natural materials for hair loss prevention hair preparation containing natural products include ginseng, mulberry, black bean, Ogaki and Gugija are widely used, and researches using charcoal, loess, etc. have been carried out recently.
현재 의약외품으로 약국에 출시된 탈모치료제는 현대약품의 ‘마이녹실’, 동국제약 ‘판시딜’, 코오롱제약이 생산하여 태전약품이 판매하는 ‘드로젠정’, 동성제약의 ‘미녹시딜’ 등이 있으며 현대약품의 ‘마이녹실’이 선두를 달리고 있다. There are currently Hyundai Pharm 's' Minoxil ', Dongkuk Pharm' Panxidil ', Kolon Pharm' s 'De Rosen', and Dongsung Pharm 'Minoxidil' Drugs 'minoxyl' is leading.
최근 탈모치료제는 바르는 약에서 먹는 약으로 변화하고 있고 매출 100억 원이 넘는 탈모치료제‘마이녹실’을 판매하는 현대약품은 바르는 젤타입도 출시하고 있다. Hyundai Pharm, which sells hair loss treatment drugs 'Meinoxil', sales of over 10 billion won in sales, is also launching a gel type.
의약부외품 모라클과 CJ의 직공모발력, 모앤모아가 대표적이며, 모라클은 인삼, 은행잎, 쑥, 하수오, 뽕잎, 솔잎, 호두 등 한방 생약추출물과 항산화 작용을 하는 코엔자임Q10을 첨가한 제품으로 모발 성장을 촉진시키는 제품이다. Moraxle is a product with added herbal extracts such as ginseng, ginkgo leaf, mugwort, mint leaf, mulberry leaf, pine needles and walnut, and coenzyme Q10, which is antioxidant, to promote hair growth. Products.
탈모예방 모발제 성분으로 계면활성제 등의 화학성분 보다는 인체 부작용이 적은 식물, 과일 성분 등의 천연물을 함유하는 탈모 방지 모발제의 개발이 진행되고 있는 실정이다. Development of a hair loss prevention hair preparation containing natural products such as plants and fruit components, which have less side effects on human body than chemical components such as surfactants, is proceeding.
탈모의 원인으로는 유전적, 남성호르몬, 스트레스와 빈혈, 천식, 고혈압, 동맥경화, 당뇨 등 질병과 현대 사회의 식습관 및 환경 오염에 의한 원인이 있다. Causes of hair loss include genetic, male hormones, stress and anemia, asthma, hypertension, atherosclerosis, diabetes and other diseases caused by eating habits and environmental pollution in modern society.
면역계 이상에 의해 발생하는 원형탈모의 가장 큰 원인은 스트레스이며, 최근 이러한 증상을 호소하는 여성 및 소아 탈모자가 전체 탈모 인구의 약 40%에 달해 이에 대한 해결이 시급함. 또한 탈모로 인한 외형적인 변화는 스트레스를 더 급증시켜 증상을 가속화 시키는 부작용 또한 동반되어 나타난다. The most common cause of amenorrhea caused by the immune system abnormality is stress. Recently, it is urgent to solve the problem that women and child depilation who complain about these symptoms have about 40% of the total hair loss population. Also, appearance changes due to hair loss are accompanied by side effects that further accelerate symptoms by increasing stress.
이와 같이 최근 환경오염, 약물의 오남용 등에 의한 부작용, 사회 환경적이 스트레스 등으로 남녀노소에 상관없이 탈모 인구가 계속하여 증가하고 있어 이를 예방하고 발모를 촉진하는 인체 무해한 천연 물질을 이용한 제품 개발 필요성이 대두되고 있는 실정이다.As a result, the need for product development using harmless natural substances that promote hair growth and prevention of hair loss is increasing due to recent environmental pollution, side effects such as abuse of drugs, social stress, and so on. .
본 발명에서는 탈모 예방 및 두피 개선 효과가 우수한 천연 소재를 발굴하고, 그 천연소재의 안전성/유효성/표준화를 확보하여 우수한 제형 개발을 통해 효과적으로 두피로의 유효 성분 전달을 극대화하여 유효성 및 안전성을 확보한 천연복합소재 추출물을 활용한 탈모예방 조성물 및 그의 제조방법을 제공하는 것을 그 해결과제로 한다. In the present invention, natural materials excellent in hair loss prevention and scalp improvement effects are searched and the safety / effectiveness / standardization of the natural materials are secured, so that effective formulation of effective ingredients is effectively maximized through development of excellent formulations, It is an object of the present invention to provide a composition for preventing hair loss using natural complex material extract and a method for producing the same.
상기한 과제를 해결한 본 발명의 천연복합소재 추출물을 활용한 탈모예방 조성물은 정제수와 디소듐이디티에이(Disodium EDTA)의 혼합물인 A상혼합물;고A composition for preventing hair loss using the natural complex material extract of the present invention which solves the above problems comprises an A phase mixture which is a mixture of purified water and disodium EDTA;
구아하이드록시프로필트리모늄클로라이드(Guar Hydroxypropyltrimonium Chloride)로 되는 점증제인 B상화합물;A B-phase compound which is an initiator of guar hydroxypropyltrimonium chloride;
폴리쿼터늄-10(Polyquaternium-10)로 되는 모발고정제인 C상화합물;A C-phase compound which is a hair fixing agent made of Polyquaternium-10;
시트릭애씨드(Citric Acid)와 하이드로제네이티드포리데센(Hydrogenated Polydecene)과 디메치콘(Dimethicone)으로 이루어진 제1혼합물과, 정제수와 디메치콘/비닐디메치콘크로스폴리머(Dimethicone/Vinyl Dimethicone Crosspolymer)와 C12-14 파레스-12(C12-14 Pareth-12)로 이루어진 제2혼합물과, 글라이콜디스테아레이트와, 정제수와 코카미도프로필베타인(Cocamidopropyl Betaine)과 소듐클로라이드(Sodium Chloride)로 이루어진 제3혼합물과, 코카마이드엠이에이(Cocamide MEA)와, 정제수와 소듐라우레스설페이트(Sodium Laureth Sulfate)와 시트릭애씨드(Citric Acid)와 소듐카보네이트(Sodium carbonate)로 이루어진 제4혼합물과, 정제수와 소듐라우레스설페이트(Sodium Laureth Sulfate)와 페녹시에탄올(phenoxyethanol)로 이루어진 제5혼합물을 혼합하여 이루어진 D상혼합물;A first mixture of Citric Acid and Hydrogenated Polydecene and Dimethicone and a first mixture of purified water, Dimethicone / Vinyl Dimethicone Crosspolymer and C12- (C12-14 Pareth-12), and a third mixture consisting of glycol distearate and purified water and a mixture of Cocamidopropyl Betaine and Sodium Chloride A fourth mixture of purified water and sodium laureth sulfate and citric acid and sodium carbonate and a fourth mixture of purified water and sodium laureth sulfate, A D phase mixture prepared by mixing a fifth mixture of sodium laureth sulfate and phenoxyethanol;
정제수와 소듐클로라이드(Sodium Chloride)의 혼합물인 E상혼합물;An E phase mixture which is a mixture of purified water and sodium chloride;
항균제(Phytonside-HD)와 오가닉(Organic)혼합물과 보습제와 천연물 추출물 복합화합물로 이루어진 F상혼합물;An F-phase mixture consisting of an antibacterial agent (Phytonside-HD) and an organic compound, a humectant and a natural compound;
향료의 G상 화합물을 순차적으로 혼합하여 이루어지는 것을 특징으로 한다. And a G-phase compound of a perfume are sequentially mixed.
여기서, 상기 조성물은 A상 혼합물 30~32중량부; B상화합물 0.15~0.25중량부; C상화합물 0.4~0.5중량부; D상혼합물 59~60중량부; E상혼합물 3.0~3.5중량부; F상혼합물 3.5~4.0중량부 및 G상화합물 1.2~1.8중량부를 포함하여 이루어지는 것을 특징으로 한다.Wherein the composition comprises 30 to 32 parts by weight of the A phase mixture; 0.15 to 0.25 parts by weight of a B-phase compound; 0.4 to 0.5 parts by weight of a C-phase compound; 59 to 60 parts by weight of the D phase mixture; 3.0 to 3.5 parts by weight of an E phase mixture; 3.5 to 4.0 parts by weight of the F phase mixture and 1.2 to 1.8 parts by weight of the G phase compound.
여기서, 상기 F상혼합물을 구성하는 항균제는 벤질글라이콜(Benzyl Glycol)과 부톡시디글라이콜(Butoxydiglycol)과 라스베리케톤(Raspberry Ketone)을 혼합하여 이루어지며, 그 혼합비율은 0.6~0.7:0.1~0.11:0.03~0.035의 중량비로 혼합되는 것을 특징으로 한다. Herein, the antibacterial agent constituting the F-phase mixture is a mixture of benzyl glycols, butoxydiglycol, and raspberry ketone, and the mixing ratio thereof is 0.6 to 0.7: 0.1 To 0.11: 0.03 to 0.035.
여기서, 상기 F상혼합물을 구성하는 오가닉(Organic)혼합물은 정제수, 부틸렌글라이콜(Butylene Glycol), 셀러리추출물, 쌀추출물, 양배추잎추출물, 순무잎추출물, 토마토열매 추출물, 당근추출물, 브로콜리추출물, 페녹시에탄올(phenoxyethanol), 에칠헥실글리세린을 혼합하여 이루어지는 것을 특징으로 한다. Here, the organic mixture constituting the above-mentioned F-phase mixture may be purified water, Butylene Glycol, celery extract, rice extract, cabbage leaf extract, sorghum extract, tomato fruit extract, carrot extract, broccoli extract, Phenoxyethanol, and ethylhexyl glycerin are mixed with each other.
여기서, 상기 F상혼합물을 구성하는 보습제는 정제수, 소듐하이알루로네이트(Sodium Hyaluronate) 및 페녹시에탄올(phenoxyethanol)을 혼합하여 되며, 그 혼합량은 0.9~1.0:0.09~0.012:0.005~0.007의 중량비로 혼합한 것을 특징으로 한다. Here, the humectant constituting the F-phase mixture is a mixture of purified water, sodium hyaluronate and phenoxyethanol, and the mixing ratio thereof is in the range of 0.9 to 1.0: 0.09 to 0.012: 0.005 to 0.007 .
여기서, 상기 F상혼합물을 구성하는 천연물 추출물 복합화합물은 산수유추출물; 구기자추출물; 산뽕나무잎추출물; 쌀겨추출물; 오미자추출물; 대추추출물; 녹차추출물; 감추출물; 은행잎추출물; 자소엽추출물; 귤껍질추출물; 더덕추출물; 큰조롱뿌리추출물; 인삼추출물; 길경추출물; 하수오추출물; 둥굴레추출물; 콩싹추출물; 가시오갈피뿌리추출물; 감초추출물; 청호추출물; 어성초추출물; 엉겅퀴꽃 추출물, 엉겅퀴잎 추출물 또는 엉겅퀴줄기추출물중 어느 하나의 추출물, 서양민들레추출물, 호스테일켈프추출물, 포공영추출물 및 정제수를 혼합하여 이루어지는 것을 특징으로 한다. Herein, the complex compound of the natural substance extract constituting the above-mentioned F-phase mixture is selected from the group consisting of corn oil extract; Gugija extract; Mulberry leaf extract; Rice bran extract; Omija extract; Jujube extract; Green tea extract; Persimmon extract; Ginkgo biloba extract; Leaf lobule extract; Tangerine peel extract; Roots extract; Large morsel root extract; Ginseng extract; Gakgyeong extract; Sashou Extract; Donguli extract; Sprout extract; Acanthopanax root extract; Licorice extract; Cheongho extract; Horsetail extract; Thistle flower extract, thistle leaf extract, or thistle stem extract, a dandelion dandelion extract, a horsetail kelp extract, a perennial extract, and purified water.
여기서, 상기 F상혼합물은 항균제(Phytonside-HD)와 오가닉(Organic)혼합물과 보습제와 천연물 추출물 복합화합물의 혼합비율은 8:0.01:10:20의 중량비로 혼합하는 것을 특징으로 한다. Here, the F-phase mixture is characterized in that the mixing ratio of the antibacterial agent (Phytonside-HD), the organic mixture, the moisturizing agent and the natural compound extract compound is 8: 0.01: 10: 20 by weight.
여기서, 상기 D상 혼합물은 제1혼합물과 제2혼합물과 글리콜디스테아레이트와 제3혼합물과 코카마이드엠이에이와 제4혼합물과 제5혼합물의 혼합비율은 0.81:0.5:3.5:7.5:3.0:24.0:20.0의 중량비로 혼합되는 것을 특징으로 한다. The mixture of the first mixture and the second mixture, the glycol distearate, the third mixture, the cocamide mime, the fourth mixture and the fifth mixture is 0.81: 0.5: 3.5: 7.5: 3.0: 24.0: 20.0 by weight.
여기서, 상기 조성물은 점도 ( )~( )cps, pH ( )~( )인 것을 특징으로 한다. Here, the composition is characterized by having viscosity () ~ () cps and pH () ~ ().
또한, 본 발명에서는 정제수와 디소듐이디티에이(Disodium EDTA)의 혼합물을 준비하고, 유화가마에 투입하여 온도 80±2℃, 60rpm의 교반속도로 30분간 가온용해하는 제1단계;In addition, in the present invention, a mixture of purified water and disodium EDTA is prepared, and the mixture is put into an oil painting kiln and melted at a temperature of 80 ± 2 ° C and a stirring speed of 60 rpm for 30 minutes.
상기 제1단계의 가온용해 후, 구아하이드록시프로필트리모늄클로라이드(Guar Hydroxypropyltrimonium Chloride)를 서서히 투입하여 온도 80±2℃, 60rpm의 교반속도로 30분간 용해하는 제2단계;A second step of slowly adding guar hydroxypropyltrimonium chloride to the solution after the first step of dissolving the solution by heating, and dissolving the solution at a stirring rate of 60 캜 for 30 minutes at a temperature of 80 캜 and a temperature of 80 캜;
상기 제2단계의 용해가 완료된 후, 폴리쿼터늄-10(Polyquaternium-10)을 서서히 투입하여 온도 80±2℃, 60rpm의 교반속도로 30분간 용해하는 제3단계;After the completion of the dissolution in the second step, Polyquaternium-10 is gradually added and dissolved at a temperature of 80 2 캜 and a stirring speed of 60 rpm for 30 minutes.
상기 제3단계의 용해가 완료된 후, 시트릭애씨드(Citric Acid)와 하이드로제네이티드포리데센(Hydrogenated Polydecene)과 디메치콘(Dimethicone)으로 이루어진 제1혼합물과, 정제수와 디메치콘/비닐디메치콘크로스폴리머(Dimethicone/Vinyl Dimethicone Crosspolymer)와 C12-14 파레스-12(C12-14 Pareth-12)로 이루어진 제2혼합물과, 글라이콜디스테아레이트와, 정제수와 코카미도프로필베타인(Cocamidopropyl Betaine)과 소듐클로라이드(Sodium Chloride)로 이루어진 제3혼합물과, 코카마이드엠이에이(Cocamide MEA)와, 정제수와 소듐라우레스설페이트(Sodium Laureth Sulfate)와 시트릭애씨드(Citric Acid)와 소듐카보네이트(Sodium carbonate)로 이루어진 제4혼합물과, 정제수와 소듐라우레스설페이트(Sodium Laureth Sulfate)와 페녹시에탄올(phenoxyethanol)로 이루어진 제5혼합물을 혼합하여 이루어진 혼합물을 준비하고, 준비된 혼합물을 서서히 투입하여 온도 80±2℃, 60rpm의 교반속도로 30분간 용해하는 제4단계;After the completion of the dissolution in the third step, a first mixture consisting of Citric Acid, Hydrogenated Polydecene and Dimethicone, and a mixture of purified water and dimethicone / vinyl dimethicone crosspolymer A second mixture consisting of Dimethicone / Vinyl Dimethicone Crosspolymer and C12-14 Pareth-12, glycol distearate, purified water, cocamidopropyl betaine, sodium A third mixture consisting of sodium chloride and a mixture of cocamide MEA and purified water and sodium laureth sulfate and citric acid and sodium carbonate, A fourth mixture, and a fifth mixture consisting of purified water and sodium laureth sulfate and phenoxyethanol were prepared, The resulting mixture was slowly added to the mixture, and the mixture was dissolved at a temperature of 80 캜 and a stirring speed of 60 rpm for 30 minutes.
상기 제4단계의 용해가 완료된 후, 정제수와 소듐클로라이드(Sodium Chloride)의 혼합물을 준비하고, 상기 혼합물을 투입하여 온도 80±2℃, 60rpm의 교반속도로 30분간 용해하는 제5단계;After the completion of the dissolution in the fourth step, a mixture of purified water and sodium chloride is prepared, and the mixture is put in a fifth step of dissolving the mixture at a stirring rate of 60 ± 2 ° C for 30 minutes at a temperature of 80 ± 2 ° C.
상기 제5단계의 용해가 완료된 후, 용해물의 온도를 40±2℃가 되도록 냉각한 후, 항균제(Phytonside-HD)와 오가닉(Organic)혼합물과 보습제와 천연물 추출물 복합화합물로 이루어진 혼합물을 투입하여 온도 40±2℃, 60rpm의 교반속도로 30분간 용해하는 제6단계;After the dissolution of the fifth step is completed, the temperature of the lysate is cooled to 40 ± 2 ° C., and a mixture of an antibacterial agent (Phytonside-HD) and an organic mixture, a humectant and a natural compound A sixth step of dissolving at a temperature of 40 2 캜 for 30 minutes at a stirring speed of 60 rpm;
상기 제6단계의 용해가 완료된 후, 향료를 투입하여 패들믹서로 50~60rpm의 교반속도로 10~20분간 교반혼합하고, 이후 호모믹서를 이용하여 2500~3500rpm으로 2~4분 교반한 후, 마이크로플로다이저(microfludizer)에서 700~1,000bar압력으로 3회 반복처리하는 제7단계를 포함하여 이루어지는 천연복합소재 추출물을 활용한 탈모예방 조성물의 제조방법을 제공한다.After the completion of the dissolution in the sixth step, perfume was added thereto, and the mixture was stirred with a paddle mixer at a stirring speed of 50 to 60 rpm for 10 to 20 minutes, followed by stirring at 2500 to 3500 rpm for 2 to 4 minutes using a homomixer, And a seventh step of repeating the treatment at a pressure of 700 to 1,000 bar in a microfludizer three times. The present invention also provides a method of preparing a composition for preventing hair loss using the natural composite extract.
여기서, 상기 제6단계의 혼합물은 항균제(Phytonside-HD)와 오가닉(Organic)혼합물과 보습제와 천연물 추출물 복합화합물의 혼합비율은 8:0.01:10:20의 중량비로 혼합한 혼합물인 것을 특징으로 한다. Here, the mixture in the sixth step is a mixture of a mixture of an antimicrobial agent (Phytonside-HD) and an organic compound, a humectant and a complex compound of a natural product extract in a weight ratio of 8: 0.01: 10: 20 .
여기서, 상기 제6단계의 혼합물을 구성하는 항균제는 벤질글라이콜(Benzyl Glycol)과 부톡시디글라이콜(Butoxydiglycol)과 라스베리케톤(Raspberry Ketone)을 혼합하여 이루어지며, 그 혼합비율은 0.6~0.7:0.1~0.11:0.03~0.035의 중량비로 혼합되는 것을 특징으로 한다. Herein, the antibacterial agent constituting the mixture of the sixth step is prepared by mixing Benzyl Glycol, Butoxydiglycol, and Raspberry Ketone, and the mixing ratio thereof is 0.6 to 0.7 : 0.1 to 0.11: 0.03 to 0.035.
여기서, 상기 제6단계의 혼합물을 구성하는 오가닉(Organic)혼합물은 정제수, 부틸렌글라이콜(Butylene Glycol), 셀러리추출물, 쌀추출물, 양배추잎추출물, 순무잎추출물, 토마토열매 추출물, 당근추출물, 브로콜리추출물, 페녹시에탄올(phenoxyethanol), 에칠헥실글리세린을 혼합하여 이루어지는 것을 특징으로 한다. Herein, the organic mixture constituting the mixture of the sixth step is purified water, butylene glycol, celery extract, rice extract, cabbage leaf extract, nettle leaf extract, tomato fruit extract, carrot extract, broccoli An extract, phenoxyethanol, and ethylhexyl glycerin.
여기서, 상기 제6단계의 혼합물을 구성하는 보습제는 정제수, 소듐하이알루로네이트(Sodium Hyaluronate) 및 페녹시에탄올(phenoxyethanol)을 혼합하여 되며, 그 혼합량은 0.9~1.0:0.09~0.012:0.005~0.007의 중량비로 혼합한 것을 특징으로 한다. Herein, the humectant constituting the mixture of the sixth step is mixed with purified water, sodium hyaluronate, and phenoxyethanol, and the mixing amount thereof is 0.9-1.0: 0.09-0.012: 0.005-0.007 By weight.
여기서, 상기 제6단계의 혼합물을 구성하는 천연물 추출물 복합화합물은 산수유추출물; 구기자추출물; 산뽕나무잎추출물; 쌀겨추출물; 오미자추출물; 대추추출물; 녹차추출물; 감추출물; 은행잎추출물; 자소엽추출물; 귤껍질추출물; 더덕추출물; 큰조롱뿌리추출물; 인삼추출물; 길경추출물; 하수오추출물; 둥굴레추출물; 콩싹추출물; 가시오갈피뿌리추출물; 감초추출물; 청호추출물; 어성초추출물; 엉겅퀴꽃 추출물, 엉겅퀴잎 추출물 또는 엉겅퀴줄기추출물중 어느 하나의 추출물, 서양민들레추출물, 호스테일켈프추출물, 포공영추출물 및 정제수를 혼합하여 이루어지는 것을 특징으로 한다. Herein, the natural-substance-extract complex compound constituting the mixture of the sixth step may be selected from the group consisting of corn oil extract; Gugija extract; Mulberry leaf extract; Rice bran extract; Omija extract; Jujube extract; Green tea extract; Persimmon extract; Ginkgo biloba extract; Leaf lobule extract; Tangerine peel extract; Roots extract; Large morsel root extract; Ginseng extract; Gakgyeong extract; Sashou Extract; Donguli extract; Sprout extract; Acanthopanax root extract; Licorice extract; Cheongho extract; Horsetail extract; Thistle flower extract, thistle leaf extract, or thistle stem extract, a dandelion dandelion extract, a horsetail kelp extract, a perennial extract, and purified water.
본 발명에 따라 제공되는 천연복합소재 추출물을 활용한 탈모예방 조성물은 유효성 및 안정성이 확보된 천연소재 복합 추출물을 함유함으로써 피부내 침투시 탁월한 효능 및 효과를 가지는 탈모예방 조성물을 제공할 수 있다. The anti-hair loss composition using the natural complex material extract provided according to the present invention can provide a composition for preventing hair loss, which has excellent efficacy and effect when penetrating into the skin, by containing the natural material complex extract having secured effectiveness and stability.
또한, 인체에 무해한 천연식물 추출 복합소재를 포함함으로써 탈모 방지 및 발모 촉진용 모발 화장품으로의 제품 개발이 가능하며, 스프레이 형태로 개발하여 두피에 직접 분사하여 두피 마사지 등에 사용이 가능한 제품 등 천연 추출물을 이용한 다양한 형태로의 사용이 용이하고, 인체 무해한 제품 개발이 가능한 효과를 가진다. In addition, it can be developed as a hair cosmetic product for prevention of hair loss and promotion of hair growth by including a natural plant extract compound material harmless to the human body. It is developed as a spray type and sprayed directly on the scalp, It is easy to use in various forms using it, and it is possible to develop a product harmless to human body.
또한, 본 발명에서 제공되는 천연복합소재 추출물을 활용한 탈모예방 조성물은 과다 피지 분비 등 두피 질환으로 인한 탈모의 가속화를 방지하고 두피 개선 효과를 추가적으로 가지는 복합 소재 및 제품 개발이 가능한 효과가 있다. In addition, the composition for preventing hair loss using the natural complex material extract of the present invention has the effect of preventing the acceleration of hair loss due to scalp diseases such as excessive sebum secretion and developing a composite material and a product having an additional scalp improvement effect.
이하, 본 발명을 보다 상세히 설명하기로 한다. Hereinafter, the present invention will be described in more detail.
본 발명은 탈모예방 및 두피 개선효과가 우수한 천연복합소재 추출물을 활용한 탈모예방 조성물 및 그의 제조방법에 관한 것으로, 본 발명에서는 탈모 예방 및 두피 개선 효과가 우수한 천연 소재를 발굴하고, 그 천연소재의 안전성/유효성/표준화를 확보하여 우수한 제형 개발을 통해 효과적으로 두피로의 유효 성분 전달을 극대화 하여 유효성 및 안전성을 확보한 천연복합소재 추출물을 활용한 탈모예방 조성물 및 그의 제조방법을 제공하고자 한다. The present invention relates to a composition for preventing hair loss and a method for preparing the same, which uses a natural complex material extract having excellent hair loss preventing effect and scalp improvement effect. In the present invention, natural materials excellent in hair loss prevention and scalp improvement effects are discovered, The present invention provides a composition for preventing hair loss and a method for producing the same, which utilizes a natural composite extract obtained by securing safety / efficacy / standardization and maximizing effective ingredient delivery to the scalp through effective formulation development and securing efficacy and safety.
본 발명에 따르면, 제공하고자 하는 천연복합소재 추출물을 활용한 탈모예방 조성물은 정제수와 디소듐이디티에이(Disodium EDTA)의 혼합물인 A상혼합물;과, 구아하이드록시프로필트리모늄클로라이드(Guar Hydroxypropyltrimonium Chloride)로 되는 점증제인 B상화합물;과, 폴리쿼터늄-10(Polyquaternium-10)로 되는 모발고정제인 C상화합물;과, 시트릭애씨드(Citric Acid)와 하이드로제네이티드포리데센(Hydrogenated Polydecene)과 디메치콘(Dimethicone)으로 이루어진 제1혼합물과, 정제수와 디메치콘/비닐디메치콘크로스폴리머(Dimethicone/Vinyl Dimethicone Crosspolymer)와 C12-14 파레스-12(C12-14 Pareth-12)로 이루어진 제2혼합물과, 글라이콜디스테아레이트와, 정제수와 코카미도프로필베타인(Cocamidopropyl Betaine)과 소듐클로라이드(Sodium Chloride)로 이루어진 제3혼합물과, 코카마이드엠이에이(Cocamide MEA)와, 정제수와 소듐라우레스설페이트(Sodium Laureth Sulfate)와 시트릭애씨드(Citric Acid)와 소듐카보네이트(Sodium carbonate)로 이루어진 제4혼합물과, 정제수와 소듐라우레스설페이트(Sodium Laureth Sulfate)와 페녹시에탄올(phenoxyethanol)로 이루어진 제5혼합물을 혼합하여 이루어진 D상혼합물;과, 정제수와 소듐클로라이드(Sodium Chloride)의 혼합물인 E상혼합물;과, 항균제(Phytonside-HD)와 오가닉(Organic)혼합물과 보습제와 천연물 추출물 복합화합물로 이루어진 F상혼합물;과 향료의 G상 화합물을 순차적으로 혼합하여 이루어지는 것에 그 특징이 있다. According to the present invention, a composition for preventing hair loss using a natural complex material extract to be provided is characterized by comprising an A phase mixture, which is a mixture of purified water and disodium EDTA, and a guar hydroxypropyltrimonium chloride , A C-phase compound which is a hair fixing agent made of Polyquaternium-10, Citric Acid, Hydrogenated Polydecene, A second mixture consisting of purified water, dimethicone / vinyl dimethicone crosspolymer and C12-14 Pareth-12, and a first mixture of dimethicone and dimethicone, , A third mixture of glycol distearate, purified water and cocamidopropyl betaine and sodium chloride, and a third mixture of cocamide MEA, , A fourth mixture consisting of purified water, sodium laureth sulfate, citric acid and sodium carbonate, purified water, sodium laureth sulfate and phenoxyethanol phenoxyethanol), an E-phase mixture, which is a mixture of purified water and sodium chloride, an antimicrobial agent (Phytonside-HD), an organic mixture, a humectant and a natural product An F-phase mixture composed of an extract compound complex and a G-phase compound of a perfume are successively mixed.
본 발명에 따르면, 상기 조성물은 A상 혼합물 30~32중량부; B상화합물 0.15~0.25중량부; C상화합물 0.4~0.5중량부; D상혼합물 59~60중량부; E상혼합물 3.0~3.5중량부; F상혼합물 3.5~4.0중량부 및 G상화합물 1.2~1.8중량부를 포함하여 이루어지는 것에 그 특징이 있다. According to the present invention, the composition comprises 30 to 32 parts by weight of the A phase mixture; 0.15 to 0.25 parts by weight of a B-phase compound; 0.4 to 0.5 parts by weight of a C-phase compound; 59 to 60 parts by weight of the D phase mixture; 3.0 to 3.5 parts by weight of an E phase mixture; 3.5 to 4.0 parts by weight of the F phase mixture and 1.2 to 1.8 parts by weight of the G phase compound.
본 발명에 따르면, 상기 F상혼합물을 구성하는 항균제는 벤질글라이콜(Benzyl Glycol)과 부톡시디글라이콜(Butoxydiglycol)과 라스베리케톤(Raspberry Ketone)을 혼합하여 이루어지며, 바람직하게 그 혼합비율은 0.6~0.7:0.1~0.11:0.03~0.035의 중량비로 혼합되는 혼합물을 사용하는 것이다. According to the present invention, the antibacterial agent constituting the F-phase mixture is prepared by mixing Benzyl Glycol, Butoxydiglycol, and Raspberry Ketone, 0.6 to 0.7: 0.1 to 0.11: 0.03 to 0.035.
본 발명에 따르면, 상기 F상혼합물을 구성하는 오가닉(Organic)혼합물은 정제수, 부틸렌글라이콜(Butylene Glycol), 셀러리추출물, 쌀추출물, 양배추잎추출물, 순무잎추출물, 토마토열매 추출물, 당근추출물, 브로콜리추출물, 페녹시에탄올(phenoxyethanol), 에칠헥실글리세린을 혼합하여 이루어지는 것에 그 특징이 있다. 바람직하게 상기 혼합물을 구성하는 각각의 구성성분의 혼합은 오가닉추출물에 해당하는 셀러리추출물, 쌀추출물, 양배추잎추출물, 순무잎추출물, 토마토열매 추출물, 당근추출물, 브로콜리추출물은 혼합시 동일한 중량비로 첨가되며, 바람직하게는 정제수 100중량부에 대하여, 각각의 추출물 0.29~0.3중량부를 혼합하는 것이다. 또한, 정제수 100중량부에 대하여, 상기 부틸렌글라이콜은 44~45중량부를, 상기 페녹시에탄올은 1.3~1.35중량부를, 상기 에칠헥실글리세린은 0.14~0.15중량부를 혼합하는 것이 바람직하다. According to the present invention, the organic mixture constituting the above-mentioned F-phase mixture can be purified water, butylene glycol, celery extract, rice extract, cabbage leaf extract, nettle leaf extract, tomato fruit extract, carrot extract, Broccoli extract, phenoxyethanol, and ethylhexyl glycerin are mixed with each other. Preferably, the mixture of the components constituting the mixture is added at the same weight ratio as the celery extract, the rice extract, the cabbage leaf extract, the cinnamon leaf extract, the tomato fruit extract, the carrot root extract and the broccoli extract corresponding to the organic extract, , Preferably 0.29 to 0.3 parts by weight of each extract is mixed with 100 parts by weight of purified water. It is preferable that 44 to 45 parts by weight of the butylene glycol, 1.3 to 1.35 parts by weight of the phenoxyethanol and 0.14 to 0.15 part by weight of the ethylhexyl glycerin are mixed with 100 parts by weight of the purified water.
본 발명에 따르면, 상기 F상혼합물을 구성하는 보습제는 정제수, 소듐하이알루로네이트(Sodium Hyaluronate) 및 페녹시에탄올(phenoxyethanol)을 혼합하여 되며, 그 혼합량은 0.9~1.0:0.09~0.012:0.005~0.007의 중량비로 혼합하는 것이 바람직하다. According to the present invention, the humectant constituting the F-phase mixture is mixed with purified water, sodium hyaluronate, and phenoxyethanol, and the mixing amount thereof is 0.9-1.0: 0.09-0.012: 0.007. ≪ / RTI >
본 발명에 따르면, 상기 F상혼합물을 구성하는 천연물 추출물 복합화합물은 산수유추출물; 구기자추출물; 산뽕나무잎추출물; 쌀겨추출물; 오미자추출물; 대추추출물; 녹차추출물; 감추출물; 은행잎추출물; 자소엽추출물; 귤껍질추출물; 더덕추출물; 큰조롱뿌리추출물; 인삼추출물; 길경추출물; 하수오추출물; 둥굴레추출물; 콩싹추출물; 가시오갈피뿌리추출물; 감초추출물; 청호추출물; 어성초추출물; 엉겅퀴꽃 추출물, 엉겅퀴잎 추출물 또는 엉겅퀴줄기추출물중 어느 하나의 추출물, 서양민들레추출물, 호스테일켈프추출물, 포공영추출물 및 정제수를 혼합하여 이루어지는 것에 그 특징이 있다. 바람직하게 상기 복합화합물을 구성하는 각각의 천연물 추출물은 동일한 중량비로 혼합되는 것이 좋으며, 상기 정제수는 상기 천연물 추출물 100중량부에 대하여 0.15~0.17중량부를 혼합하는 것이다. According to the present invention, the natural-substance-extract complex compound constituting the above-mentioned F-phase mixture can be obtained by extracting corn oil; Gugija extract; Mulberry leaf extract; Rice bran extract; Omija extract; Jujube extract; Green tea extract; Persimmon extract; Ginkgo biloba extract; Leaf lobule extract; Tangerine peel extract; Roots extract; Large morsel root extract; Ginseng extract; Gakgyeong extract; Sashou Extract; Donguli extract; Sprout extract; Acanthopanax root extract; Licorice extract; Cheongho extract; Horsetail extract; Thistle flower extract, thistle leaf extract, or thistle stem extract, a dandelion dandelion extract, a horsetail kelp extract, a perennial extract, and purified water. Preferably, each of the natural extracts constituting the complex compound is mixed at the same weight ratio, and the purified water is mixed with 0.15 to 0.17 parts by weight per 100 parts by weight of the natural extract.
본 발명에 따르면, 상기 F상혼합물을 구성하는 항균제(Phytonside-HD)와 오가닉(Organic)혼합물과 보습제와 천연물 추출물 복합화합물의 혼합비율은 8:0.01:10:20의 중량비로 혼합하는 것이 바람직하다. According to the present invention, it is preferable that the mixing ratio of the antibacterial agent (Phytonside-HD), the organic mixture, the moisturizing agent and the natural-substance-extracting complex compound constituting the F-phase mixture is in the ratio of 8: 0.01: 10: 20 .
본 발명에 따르면, 상기 D상 혼합물은 제1혼합물과 제2혼합물과 글리콜디스테아레이트와 제3혼합물과 코카마이드엠이에이와 제4혼합물과 제5혼합물의 혼합비율은 0.81:0.5:3.5:7.5:3.0:24.0:20.0의 중량비로 혼합되는 것이 바람직하다. According to the present invention, the D phase mixture has a mixing ratio of the first mixture, the second mixture, the glycol distearate, the third mixture, the cocamide mie, the fourth mixture and the fifth mixture is 0.81: 0.5: 3.5: 7.5 : 3.0: 24.0: 20.0.
이때, 사익 제1혼합물은 시트릭애씨드(Citric Acid)와 하이드로제네이티드포리데센(Hydrogenated Polydecene)과 디메치콘(Dimethicone)을 11:20:50의 중량비로 혼합하여 이루어지고, 상기 제2혼합물은 정제수와 디메치콘/비닐디메치콘크로스폴리머(Dimethicone/Vinyl Dimethicone Crosspolymer)와 C12-14 파레스-12(C12-14 Pareth-12)를 16.75:31.5:1.75의 중량비로 혼합하여 이루어지며, 상기 제3혼합물은 정제수와 코카미도프로필베타인(Cocamidopropyl Betaine)과 소듐클로라이드(Sodium Chloride)를 48.75:22.5:3.75의 중량비로 혼합하여 이루어지며, 상기 제4혼합물은 코카마이드엠이에이(Cocamide MEA)와, 정제수와 소듐라우레스설페이트(Sodium Laureth Sulfate)와 시트릭애씨드(Citric Acid)와 소듐카보네이트(Sodium carbonate)를 16.74~16.75:7.2:0.028~0.029:0.024의 중량비로 혼합하여 이루어지며, 상기 제5혼합물은 정제수와 소듐라우레스설페이트(Sodium Laureth Sulfate)와 페녹시에탄올(phenoxyethanol)을 13.9:6.0:0.1의 중량비로 혼합하여 이루어지는 것에 그 특징이 있다. At this time, the first mixture of sesame is prepared by mixing Citric Acid, Hydrogenated Polydecene and Dimethicone in a weight ratio of 11:20:50, and the second mixture is a mixture of purified water (Dimethicone / Vinyl Dimethicone Crosspolymer) and C12-14 Pareth-12 at a weight ratio of 16.75: 31.5: 1.75, and the third mixture is a mixture of dimethicone / vinyl dimethicone crosspolymer and C12-14 Pareth- Wherein the fourth mixture is prepared by mixing purified water with cocamidopropyl betaine and sodium chloride in a weight ratio of 48.75: 22.5: 3.75, and the fourth mixture is prepared by mixing Cocamide MEA, Sodium lauryl sulphate, citric acid and sodium carbonate in a weight ratio of 16.74 to 16.75: 7.2: 0.028 to 0.029: 0.024, and the fifth mixture is mixed with purified water Sodium la Sodium lauryl sulfate and phenoxyethanol in a weight ratio of 13.9: 6.0: 0.1.
본 발명에 따르면, 상기 A상 혼합물은 바람직하게 정제수와 디소듐이디티에이를 31.0~31.5:0.1의 중량비로 혼합하여 사용하는 것이 좋으며, 상기 E상혼합물은 정제수와 소듐클로라이드를 3.0:0.3의 중량비로 혼합하는 것이다. According to the present invention, the A phase mixture is preferably mixed with purified water and disodium iodide in a weight ratio of 31.0 to 31.5: 0.1. The E phase mixture is prepared by mixing purified water and sodium chloride at a weight ratio of 3.0: 0.3 .
본 발명에 따르면, 상기 B상 화합물은 점증제로서 바람직하게는 조성물 100중량부에 대하여, 0.2중량부를 포함하는 것이 좋으며, 상기 C상화합물은 모발고정제로서 조성물 100중량부에 대하여, 0.45중량부를 포함하는 것이 좋으며, 상기 Gㅅ상 화합물은 향료로서 조성물 100중량부에 대하여, 1.5중량부를 포함하도록 첨가되는 것이 바람직하다. According to the present invention, the B-phase compound preferably contains 0.2 part by weight per 100 parts by weight of the composition, and the C-phase compound preferably contains 0.45 part by weight per 100 parts by weight of the composition as a hair- It is preferable that the G-like compound is added so as to include 1.5 parts by weight with respect to 100 parts by weight of the composition as a perfume.
한편, 본 발명을 구성하는 상기 G상 화합물은 향료로서 화장품 제품에 통상 사용되는 향료 중, 적의 선택하여 사용하는 것으로, 특별히 한정하지 않는다. On the other hand, the G-phase compound constituting the present invention is not particularly limited as it is selected from among the fragrances commonly used in cosmetic products as fragrances.
이상과 같은 본 발명에 따라 제공되는 천연복합소재 추출물을 활용한 탈모예방 조성물은 점도 ( )~( )cps, pH ( )~( )의 물리적 특징을 가지게 된다. The composition for preventing hair loss using the natural complex material extract according to the present invention has the physical characteristics of viscosity () ~ () cps, pH () ~ ().
본 발명에서는 또한 이상에서 개시되는 본 발명에 따른 천연복합소재 추출물을 활용한 탈모예방 조성물의 제조방법을 제공하게 되며, 보다 상세하게는 본 발명에 따른 천연복합소재 추출물을 활용한 탈모예방 조성물의 제조방법은 정제수와 디소듐이디티에이(Disodium EDTA)의 혼합물을 준비하고, 유화가마에 투입하여 온도 80±2℃, 60rpm의 교반속도로 30분간 가온용해하는 제1단계;The present invention also provides a method of preparing a composition for preventing hair loss using the extract of natural complex material according to the present invention as described above. More specifically, the present invention provides a method for preparing a composition for preventing hair loss, The method comprises the steps of preparing a mixture of purified water and disodium EDTA, charging it into an oil painting kiln and dissolving the mixture at a temperature of 80 ± 2 ° C and a stirring speed of 60 rpm for 30 minutes;
상기 제1단계의 가온용해 후, 구아하이드록시프로필트리모늄클로라이드(Guar Hydroxypropyltrimonium Chloride)를 서서히 투입하여 온도 80±2℃, 60rpm의 교반속도로 30분간 용해하는 제2단계;A second step of slowly adding guar hydroxypropyltrimonium chloride to the solution after the first step of dissolving the solution by heating, and dissolving the solution at a stirring rate of 60 캜 for 30 minutes at a temperature of 80 캜 and a temperature of 80 캜;
상기 제2단계의 용해가 완료된 후, 폴리쿼터늄-10(Polyquaternium-10)을 서서히 투입하여 온도 80±2℃, 60rpm의 교반속도로 30분간 용해하는 제3단계;After the completion of the dissolution in the second step, Polyquaternium-10 is gradually added and dissolved at a temperature of 80 2 캜 and a stirring speed of 60 rpm for 30 minutes.
상기 제3단계의 용해가 완료된 후, 시트릭애씨드(Citric Acid)와 하이드로제네이티드포리데센(Hydrogenated Polydecene)과 디메치콘(Dimethicone)으로 이루어진 제1혼합물과, 정제수와 디메치콘/비닐디메치콘크로스폴리머(Dimethicone/Vinyl Dimethicone Crosspolymer)와 C12-14 파레스-12(C12-14 Pareth-12)로 이루어진 제2혼합물과, 글라이콜디스테아레이트와, 정제수와 코카미도프로필베타인(Cocamidopropyl Betaine)과 소듐클로라이드(Sodium Chloride)로 이루어진 제3혼합물과, 코카마이드엠이에이(Cocamide MEA)와, 정제수와 소듐라우레스설페이트(Sodium Laureth Sulfate)와 시트릭애씨드(Citric Acid)와 소듐카보네이트(Sodium carbonate)로 이루어진 제4혼합물과, 정제수와 소듐라우레스설페이트(Sodium Laureth Sulfate)와 페녹시에탄올(phenoxyethanol)로 이루어진 제5혼합물을 혼합하여 이루어진 혼합물을 준비하고, 준비된 혼합물을 서서히 투입하여 온도 80±2℃, 60rpm의 교반속도로 30분간 용해하는 제4단계;After the completion of the dissolution in the third step, a first mixture consisting of Citric Acid, Hydrogenated Polydecene and Dimethicone, and a mixture of purified water and dimethicone / vinyl dimethicone crosspolymer A second mixture consisting of Dimethicone / Vinyl Dimethicone Crosspolymer and C12-14 Pareth-12, glycol distearate, purified water, cocamidopropyl betaine, sodium A third mixture consisting of sodium chloride and a mixture of cocamide MEA and purified water and sodium laureth sulfate and citric acid and sodium carbonate, A fourth mixture, and a fifth mixture consisting of purified water and sodium laureth sulfate and phenoxyethanol were prepared, The resulting mixture was slowly added to the mixture, and the mixture was dissolved at a temperature of 80 캜 and a stirring speed of 60 rpm for 30 minutes.
상기 제4단계의 용해가 완료된 후, 정제수와 소듐클로라이드(Sodium Chloride)의 혼합물을 준비하고, 상기 혼합물을 투입하여 온도 80±2℃, 60rpm의 교반속도로 30분간 용해하는 제5단계;After the completion of the dissolution in the fourth step, a mixture of purified water and sodium chloride is prepared, and the mixture is put in a fifth step of dissolving the mixture at a stirring rate of 60 ± 2 ° C for 30 minutes at a temperature of 80 ± 2 ° C.
상기 제5단계의 용해가 완료된 후, 용해물의 온도를 40±2℃가 되도록 냉각한 후, 항균제(Phytonside-HD)와 오가닉(Organic)혼합물과 보습제와 천연물 추출물 복합화합물로 이루어진 혼합물을 투입하여 온도 40±2℃, 60rpm의 교반속도로 30분간 용해하는 제6단계;After the dissolution in the fifth step is completed, the temperature of the melt is cooled to 40 ± 2 ° C., and a mixture of an antibacterial agent (Phytonside-HD) and an organic mixture, a humectant and a natural compound A sixth step of dissolving at a temperature of 40 2 캜 for 30 minutes at a stirring speed of 60 rpm;
상기 제6단계의 용해가 완료된 후, 향료를 투입하여 패들믹서로 50~60rpm의 교반속도로 10~20분간 교반혼합하고, 이후 호모믹서를 이용하여 2500~3500rpm으로 2~4분 교반한 후, 마이크로플로다이저(microfludizer)에서 700~1,000bar압력으로 3회 반복처리하는 제7단계를 포함하여 이루어지는 것에 그 특징이 있는 것이다. After the completion of the dissolution in the sixth step, perfume was added thereto, and the mixture was stirred with a paddle mixer at a stirring speed of 50 to 60 rpm for 10 to 20 minutes, followed by stirring at 2500 to 3500 rpm for 2 to 4 minutes using a homomixer, And a seventh step of repeating the treatment three times at 700 to 1,000 bar pressure in a microfludizer.
본 발명에 따르면, 상기 제6단계의 혼합물은 항균제(Phytonside-HD)와 오가닉(Organic)혼합물과 보습제와 천연물 추출물 복합화합물의 혼합비율은 8:0.01:10:20의 중량비로 혼합한 혼합물인 것에 그 특징이 있다. According to the present invention, the mixture of the sixth step is a mixture of a mixture of an antimicrobial agent (Phytonside-HD) and an organic compound, a humectant and a complex compound of a natural product extract at a weight ratio of 8: 0.01: 10: There are features.
본 발명에 따르면, 상기 제6단계의 혼합물을 구성하는 항균제는 벤질글라이콜(Benzyl Glycol)과 부톡시디글라이콜(Butoxydiglycol)과 라스베리케톤(Raspberry Ketone)을 혼합하여 이루어지며, 그 혼합비율은 0.6~0.7:0.1~0.11:0.03~0.035의 중량비로 혼합되는 것이다. According to the present invention, the antibacterial agent constituting the mixture of the sixth step is prepared by mixing Benzyl Glycol, Butoxydiglycol, and Raspberry Ketone, 0.6 to 0.7: 0.1 to 0.11: 0.03 to 0.035.
본 발명에 따르면, 상기 제6단계의 혼합물을 구성하는 오가닉(Organic)혼합물은 정제수, 부틸렌글라이콜(Butylene Glycol), 셀러리추출물, 쌀추출물, 양배추잎추출물, 순무잎추출물, 토마토열매 추출물, 당근추출물, 브로콜리추출물, 페녹시에탄올(phenoxyethanol), 에칠헥실글리세린을 혼합하여 이루어지는 것을 사용한다. According to the present invention, the organic mixture constituting the mixture of the sixth step is purified water, butylene glycol, celery extract, rice extract, cabbage leaf extract, nettle leaf extract, tomato fruit extract, Extract, broccoli extract, phenoxyethanol, and ethylhexyl glycerin.
본 발명에 따르면, 상기 제6단계의 혼합물을 구성하는 보습제는 정제수, 소듐하이알루로네이트(Sodium Hyaluronate) 및 페녹시에탄올(phenoxyethanol)을 혼합하여 되며, 그 혼합량은 0.9~1.0:0.09~0.012:0.005~0.007의 중량비로 혼합한 것을 사용한다. According to the present invention, the humectant constituting the mixture of the sixth step is mixed with purified water, sodium hyaluronate, and phenoxyethanol, and the mixing amount thereof is 0.9-1.0: 0.09-0.012: 0.005 to 0.007 in weight ratio is used.
본 발명에 따르면, 상기 제6단계의 혼합물을 구성하는 천연물 추출물 복합화합물은 산수유추출물; 구기자추출물; 산뽕나무잎추출물; 쌀겨추출물; 오미자추출물; 대추추출물; 녹차추출물; 감추출물; 은행잎추출물; 자소엽추출물; 귤껍질추출물; 더덕추출물; 큰조롱뿌리추출물; 인삼추출물; 길경추출물; 하수오추출물; 둥굴레추출물; 콩싹추출물; 가시오갈피뿌리추출물; 감초추출물; 청호추출물; 어성초추출물; 엉겅퀴꽃 추출물, 엉겅퀴잎 추출물 또는 엉겅퀴줄기추출물중 어느 하나의 추출물, 서양민들레추출물, 호스테일켈프추출물, 포공영추출물 및 정제수를 혼합하여 이루어지는 것을 사용한다. According to the present invention, the natural-substance-extract complex compound constituting the mixture of the sixth step may be selected from the group consisting of corn oil extract; Gugija extract; Mulberry leaf extract; Rice bran extract; Omija extract; Jujube extract; Green tea extract; Persimmon extract; Ginkgo biloba extract; Leaf lobule extract; Tangerine peel extract; Roots extract; Large morsel root extract; Ginseng extract; Gakgyeong extract; Sashou Extract; Donguli extract; Sprout extract; Acanthopanax root extract; Licorice extract; Cheongho extract; Horsetail extract; Thistle extract, Thistle flower extract, Thistle leaf extract or Thistle stalk extract, Western dandelion extract, Horsetail kelp extract, Poonggolyong extract, and purified water.
이상의 제조방법을 구성하는 각 단계에서 사용되는 물질들의 혼합비율, 구성비율 등은 이상의 본 발명에 따라 개시되는 천연복합소재 추출물을 활용한 탈모예방 조성물의 설명과 같다.The mixing ratios, composition ratios, and the like of the materials used in the respective steps constituting the above manufacturing method are the same as those of the composition for preventing hair loss using the natural complex material extract disclosed in the present invention.
한편, 본 발명에 따르면, 바람직하게 상기 제6단계에서 사용되는 천연물 추출물은 증기추출법(Steam Distillation)으로 추출하여 얻어지는 추출물을 사용하는 것이 좋다. 상기 증기추출법은 각각의 천연소재의 원료를 망에 넣고 물을 가열하여 얻는 수증기를 이용해 응축, 분리하는 방법으로 순수한 물을 추출 매체로 사용하기 때문에 추출 시 사용한 용매의 독성 문제가 없어 유해성 문제가 적으며, 수율이 뛰어난 장점이 있다. (여기에, 상기 증기추출법에 대해, 단계별로 온도, 시간 등 환경조건에 대한 상세한 설명을 기재하여 주시기 바랍니다.)According to the present invention, it is preferable to use an extract obtained by extracting the natural material extract used in the sixth step by steam distillation. The steam extraction method is a method of condensing and separating water vapor by using raw materials of natural materials and heating the water. Since pure water is used as an extraction medium, there is no problem of toxicity of the solvent used in the extraction, And has an excellent yield. (Here, for the above-mentioned steam extraction method, please describe in detail the environmental conditions such as temperature, time, etc. in a step-by-step manner.)
# 본 발명에서 제조과정중의 주요특징 중 하나는 천연물질을 듀얼리포좀(나노:20~120nm)화한 나노워터인 것으로 판단됩니다. 이는 제조과정 중 마지막 7단계에서 이루어지는 것으로 판단됩니다. 즉, 최종적으로 완성되는 조성물이 나노파티클화하여 일정한 점도를 가지는 점액상의 물질에 나노파티클이 함유되는 것으로 ㅍ판단되는 바, 나노파티클을 함유하도록 하는 다층 액정 유화 시스템에 대한 상세한 제조과정에 대한 설명을 기재하여 주시기 바랍니다.One of the main features of the present invention in the present invention is that it is a nanowater with a dual liposome (nano: 20 to 120 nm) natural material. It is believed that this is done in the last 7 steps of the manufacturing process. That is, it is judged that the finally completed composition contains nanoparticles in a mucus phase material having a certain viscosity by making the nanoparticle composition, and a detailed description of a manufacturing process for a multilayer liquid crystal emulsion system including nanoparticles is described Please specify.
이하, 본 발명을 바람직한 실시형태를 들어 보다 상세히 설명하기로 한다. 단, 하기의 실시예는 본 발명을 설명하기위한 것으로서 하기 실시예로 본 발명을 한정하는 것은 아니며, 본 발명의 범위를 벗어나지 않는 범위 내에서 얼마 든지 변형 가능한 것입니다. Hereinafter, the present invention will be described in more detail with reference to preferred embodiments. However, the following examples are intended to illustrate the invention and are not to be construed as limiting the invention thereto, but are to be construed as being within the scope of the invention.
[실시예][Example]
하기 표 1에 나타낸바와 같은 조성비를 가지도록 조성물을 제조하였다. The composition was prepared so as to have a composition ratio as shown in Table 1 below.
그 제조방법은 A상을 유화가마에 투입하여 온도 80±2℃, 60rpm의 교반속도로 30분간 가온용해한 다음, B상을 소량씩 서서히 투입하여 온도 80±2℃, 60rpm의 교반속도로 30분간 용해하고, C상을 소량씩 서서히 투입하여 온도 80±2℃, 60rpm의 교반속도로 30분간 용해한다. 다음으로 D상을 용해된 상태로 준비하여, 상기 D상을 소량씩 서서히 투입하여 온도 80±2℃, 60rpm의 교반속도로 30분간 용해한 다음, E상을 투입하여 온도 80±2℃, 60rpm의 교반속도로 30분간 용해한 후, 그 용해물을 온도 40±2℃가 되도록 냉각한 후, F상을 투입하여 온도 40±2℃, 60rpm의 교반속도로 30분간 믹싱하고, 믹싱이 완료된 후 G상을 투입하여 패들믹서로 50~60rpm의 교반속도로 10~20분간 교반혼합하고, 이후 호모믹서를 이용하여 2500~3500rpm으로 2~4분 교반한 후, 마이크로플로다이저(microfludizer)에서 700~1,000bar압력으로 3회 반복처리하여 천연복합소재 추출물을 활용한 탈모예방 조성물을 제조하였다. The A phase was put into an oil painting kiln and dissolved by heating at a stirring rate of 60 ± 2 ° C. for 30 minutes. The B phase was slowly added in small portions at a temperature of 80 ± 2 ° C. and a stirring speed of 60 rpm for 30 minutes And the C phase is slowly added in small portions and dissolved at a stirring rate of 60 캜 and a temperature of 80 賊 2 캜 for 30 minutes. Next, the D phase was prepared in a dissolved state. The D phase was slowly added in small portions at a temperature of 80 2 캜 and a stirring speed of 60 rpm for 30 minutes, and then the E phase was added. The mixture was cooled to a temperature of 40 ± 2 ° C and mixed with an F phase at a stirring speed of 40 ± 2 ° C and 60 rpm for 30 minutes. After the mixing was completed, And stirred with a paddle mixer at a stirring speed of 50 to 60 rpm for 10 to 20 minutes. Thereafter, the mixture was stirred at 2500 to 3500 rpm for 2 to 4 minutes using a homomixer, and then stirred in a microfludizer for 700 to 1,000 bar pressure for 3 times to prepare a composition for preventing hair loss using a natural composite extract.
이때, 하기 표 1의 각각의 상들은 복수개의 물질로 구성되는 것은 각각의 구성성분을 칭량하여 준비한 다음 혼합하여 혼합물상태로 준비하였다. At this time, each of the phases shown in the following Table 1 was composed of a plurality of materials. Each component was weighed and prepared, and then mixed to prepare a mixture.
또한, F상을 구성하는 오가닉혼합물과 천연물추출 복합혼합물을 구성하는 천연추출물은 증기추출법으로 추출하여 준비하였다. In addition, the organic extracts constituting the F phase and the natural extracts constituting the natural product extraction complex mixture were prepared by extraction using a vapor extraction method.
(중량부)(Parts by weight)
혼합물Organic
mixture
상기 실시예에서 준비된 조성물을 물성을 테스트하여 본 결과, 점성계수 측정장치를 사용하여 측정한 점도는 ( )Pa.s 였고, pH Meter를 사용하여 측정한 pH는 ( )~( )를 나타내었다. As a result of testing the physical properties of the compositions prepared in the above examples, the viscosities measured using the viscosimetry apparatus were () Pa.s, and the pH values measured using the pH meter were () ~ ().
상기 실시예에서 준비된 조성물의 안정성 및 독성 시험, 탈모 예방 및 발모효과 시험을 실시하여 보았으며, 그 시험방법 및 결과는 이하와 같다. The stability and toxicity test of the composition prepared in the above Examples, the prevention of hair loss, and the hair growth effect test were carried out, and the test methods and results are as follows.
(하기에 기술되는 각각의 시험에 대한 시험방법과 시험에 따라 얻어진 시험결과(해당결과에 대한 표 또는 그래프 등)를 제공하여 주시기 바랍니다.)(Please provide the test method for each test described below and the test result obtained according to the test (table or graph of the result, etc.).)
<안정성 및 독성 시험><Stability and toxicity test>
1. 온도안정성 시험1. Temperature Stability Test
2. 광안정성 시험2. Light stability test
3. 세포 독성 시험(Cell cytotoxicity test) 3. Cell cytotoxicity test
4. 세포 증식 시험(Cell proliferation test)4. Cell proliferation test
5. 단회투여 독성시험5. Single-dose toxicity test
6. 반복 투여 독성시험6. Repeated dose toxicity studies
7. 생식 발생 독성시험7. Reproductive toxicity test
8. 유전독성시험8. Genotoxicity test
9. 면역 독성 시험9. Immunotoxicity test
10. 국소 독소 피부 시험10. Topical toxin skin test
<탈모예방 및 발모효과 시험><Prevention of hair loss and hair growth test>
1. 탈모예방 시험1. Hair loss prevention test
2. 발모효과 시험2. Hair growth test
Claims (15)
구아하이드록시프로필트리모늄클로라이드(Guar Hydroxypropyltrimonium Chloride)로 되는 점증제인 B상화합물;
폴리쿼터늄-10(Polyquaternium-10)로 되는 모발고정제인 C상화합물;
시트릭애씨드(Citric Acid)와 하이드로제네이티드포리데센(Hydrogenated Polydecene)과 디메치콘(Dimethicone)으로 이루어진 제1혼합물과, 정제수와 디메치콘/비닐디메치콘크로스폴리머(Dimethicone/Vinyl Dimethicone Crosspolymer)와 C12-14 파레스-12(C12-14 Pareth-12)로 이루어진 제2혼합물과, 글라이콜디스테아레이트와, 정제수와 코카미도프로필베타인(Cocamidopropyl Betaine)과 소듐클로라이드(Sodium Chloride)로 이루어진 제3혼합물과, 코카마이드엠이에이(Cocamide MEA)와, 정제수와 소듐라우레스설페이트(Sodium Laureth Sulfate)와 시트릭애씨드(Citric Acid)와 소듐카보네이트(Sodium carbonate)로 이루어진 제4혼합물과, 정제수와 소듐라우레스설페이트(Sodium Laureth Sulfate)와 페녹시에탄올(phenoxyethanol)로 이루어진 제5혼합물을 혼합하여 이루어진 D상혼합물;
정제수와 소듐클로라이드(Sodium Chloride)의 혼합물인 E상혼합물;
항균제(Phytonside-HD)와 오가닉(Organic)혼합물과 보습제와 천연물 추출물 복합화합물로 이루어진 F상혼합물;
향료의 G상 화합물을 순차적으로 혼합하여 이루어지는 천연복합소재 추출물을 활용한 탈모예방 조성물.
An A phase mixture of purified water and a mixture of disodium EDTA;
A B-phase compound which is an initiator of guar hydroxypropyltrimonium chloride;
A C-phase compound which is a hair fixing agent made of Polyquaternium-10;
A first mixture consisting of Citric Acid, Hydrogenated Polydecene and Dimethicone, a mixture of purified water, dimethicone / vinyl dimethicone crosspolymer and C12- (C12-14 Pareth-12), and a third mixture consisting of glycol distearate and purified water and a mixture of Cocamidopropyl Betaine and Sodium Chloride A fourth mixture of purified water and sodium laureth sulfate and citric acid and sodium carbonate and a fourth mixture of purified water and sodium laureth sulfate, A D phase mixture prepared by mixing a fifth mixture of sodium laureth sulfate and phenoxyethanol;
An E phase mixture which is a mixture of purified water and sodium chloride;
An F-phase mixture consisting of an antibacterial agent (Phytonside-HD) and an organic compound, a humectant and a natural compound;
And a G-phase compound of a perfume are sequentially mixed.
상기 조성물은 A상 혼합물 30~32중량부; B상화합물 0.15~0.25중량부; C상화합물 0.4~0.5중량부; D상혼합물 59~60중량부; E상혼합물 3.0~3.5중량부; F상혼합물 3.5~4.0중량부 및 G상화합물 1.2~1.8중량부를 포함하여 이루어지는 것을 특징으로 하는 천연복합소재 추출물을 활용한 탈모예방 조성물.The method according to claim 1,
The composition comprises 30 to 32 parts by weight of the A phase mixture; 0.15 to 0.25 parts by weight of a B-phase compound; 0.4 to 0.5 parts by weight of a C-phase compound; 59 to 60 parts by weight of the D phase mixture; 3.0 to 3.5 parts by weight of an E phase mixture; 3.5 to 4.0 parts by weight of an F-phase mixture and 1.2 to 1.8 parts by weight of a G-phase compound.
상기 F상혼합물을 구성하는 항균제는 벤질글라이콜(Benzyl Glycol)과 부톡시디글라이콜(Butoxydiglycol)과 라스베리케톤(Raspberry Ketone)을 혼합하여 이루어지며, 그 혼합비율은 0.6~0.7:0.1~0.11:0.03~0.035의 중량비로 혼합되는 것을 특징으로 하는 천연복합소재 추출물을 활용한 탈모예방 조성물.
The method according to claim 1,
The antibacterial agent constituting the F-phase mixture is prepared by mixing Benzyl Glycol, Butoxydiglycol and Raspberry Ketone, and the mixing ratio thereof is 0.6 to 0.7: 0.1 to 0.11 : 0.03 ~ 0.035 weight ratio.
상기 F상혼합물을 구성하는 오가닉(Organic)혼합물은 정제수, 부틸렌글라이콜(Butylene Glycol), 셀러리추출물, 쌀추출물, 양배추잎추출물, 순무잎추출물, 토마토열매 추출물, 당근추출물, 브로콜리추출물, 페녹시에탄올(phenoxyethanol), 에칠헥실글리세린을 혼합하여 이루어지는 것을 특징으로 하는 천연복합소재 추출물을 활용한 탈모예방 조성물.
The method according to claim 1,
The organic mixture constituting the above-mentioned F-phase mixture is purified water, Butylene Glycol, celery extract, rice extract, cabbage leaf extract, nettle leaf extract, tomato fruit extract, carrot extract, broccoli extract, phenoxy Phenoxyethanol, and ethylhexyl glycerin. The composition for preventing hair loss is prepared by using the extract of natural complex material.
상기 F상혼합물을 구성하는 보습제는 정제수, 소듐하이알루로네이트(Sodium Hyaluronate) 및 페녹시에탄올(phenoxyethanol)을 혼합하여 되며, 그 혼합량은 0.9~1.0:0.09~0.012:0.005~0.007의 중량비로 혼합한 것을 특징으로 하는 천연복합소재 추출물을 활용한 탈모예방 조성물.
The method according to claim 1,
Sodium hyaluronate and phenoxyethanol are mixed with the moisturizing agent constituting the above-described F-phase mixture, and the mixing amount thereof is mixed at a weight ratio of 0.9 to 1.0: 0.09 to 0.012: 0.005 to 0.007 Wherein the composition comprises a natural complex material extract.
상기 F상혼합물을 구성하는 천연물 추출물 복합화합물은 산수유추출물; 구기자추출물; 산뽕나무잎추출물; 쌀겨추출물; 오미자추출물; 대추추출물; 녹차추출물; 감추출물; 은행잎추출물; 자소엽추출물; 귤껍질추출물; 더덕추출물; 큰조롱뿌리추출물; 인삼추출물; 길경추출물; 하수오추출물; 둥굴레추출물; 콩싹추출물; 가시오갈피뿌리추출물; 감초추출물; 청호추출물; 어성초추출물; 엉겅퀴꽃 추출물, 엉겅퀴잎 추출물 또는 엉겅퀴줄기추출물중 어느 하나의 추출물, 서양민들레추출물, 호스테일켈프추출물, 포공영추출물 및 정제수를 혼합하여 이루어지는 것을 특징으로 하는 천연복합소재 추출물을 활용한 탈모예방 조성물.
The method according to claim 1,
The natural-substance-extract complex compound constituting the above-mentioned F-phase mixture is prepared by extracting corn oil; Gugija extract; Mulberry leaf extract; Rice bran extract; Omija extract; Jujube extract; Green tea extract; Persimmon extract; Ginkgo biloba extract; Leaf lobule extract; Tangerine peel extract; Roots extract; Large morsel root extract; Ginseng extract; Gakgyeong extract; Sashou Extract; Donguli extract; Sprout extract; Acanthopanax root extract; Licorice extract; Cheongho extract; Horsetail extract; Wherein the composition is made by mixing any one of an extract of Thistle flower extract, Thistle leaf extract or Thistle stem extract, Seaweed dandelion extract, Horsetail kelp extract, Poonggolyong extract, and purified water.
상기 F상혼합물은 항균제(Phytonside-HD)와 오가닉(Organic)혼합물과 보습제와 천연물 추출물 복합화합물의 혼합비율은 8:0.01:10:20의 중량비로 혼합하는 것을 특징으로 하는 천연복합소재 추출물을 활용한 탈모예방 조성물.
The method according to claim 1,
Wherein the F phase mixture is prepared by mixing a mixture of an antibacterial agent (Phytonside-HD) and an organic compound, a humectant and a natural compound extract compound at a weight ratio of 8: 0.01: 10: 20. A hair loss preventing composition.
상기 D상 혼합물은 제1혼합물과 제2혼합물과 글리콜디스테아레이트와 제3혼합물과 코카마이드엠이에이와 제4혼합물과 제5혼합물의 혼합비율은 0.81:0.5:3.5:7.5:3.0:24.0:20.0의 중량비로 혼합되는 것을 특징으로 하는 천연복합소재 추출물을 활용한 탈모예방 조성물.
The method according to claim 1,
The D phase mixture is prepared by mixing the first mixture, the second mixture, the glycol distearate, the third mixture, the cocamide mite, the fourth mixture and the fifth mixture in a mixing ratio of 0.81: 0.5: 3.5: 7.5: 3.0: 20.0. ≪ / RTI >
상기 조성물은 점도 ( )~( )Pa.s, pH ( )~( )인 것을 특징으로 하는 천연복합소재 추출물을 활용한 탈모예방 조성물.The method according to claim 1,
Wherein the composition has a viscosity () ~ () Pa.s, and a pH () ~ ().
상기 제1단계의 가온용해 후, 구아하이드록시프로필트리모늄클로라이드(Guar Hydroxypropyltrimonium Chloride)를 서서히 투입하여 온도 80±2℃, 60rpm의 교반속도로 30분간 용해하는 제2단계;
상기 제2단계의 용해가 완료된 후, 폴리쿼터늄-10(Polyquaternium-10)을 서서히 투입하여 온도 80±2℃, 60rpm의 교반속도로 30분간 용해하는 제3단계;
상기 제3단계의 용해가 완료된 후, 시트릭애씨드(Citric Acid)와 하이드로제네이티드포리데센(Hydrogenated Polydecene)과 디메치콘(Dimethicone)으로 이루어진 제1혼합물과, 정제수와 디메치콘/비닐디메치콘크로스폴리머(Dimethicone/Vinyl Dimethicone Crosspolymer)와 C12-14 파레스-12(C12-14 Pareth-12)로 이루어진 제2혼합물과, 글라이콜디스테아레이트와, 정제수와 코카미도프로필베타인(Cocamidopropyl Betaine)과 소듐클로라이드(Sodium Chloride)로 이루어진 제3혼합물과, 코카마이드엠이에이(Cocamide MEA)와, 정제수와 소듐라우레스설페이트(Sodium Laureth Sulfate)와 시트릭애씨드(Citric Acid)와 소듐카보네이트(Sodium carbonate)로 이루어진 제4혼합물과, 정제수와 소듐라우레스설페이트(Sodium Laureth Sulfate)와 페녹시에탄올(phenoxyethanol)로 이루어진 제5혼합물을 혼합하여 이루어진 혼합물을 준비하고, 준비된 혼합물을 서서히 투입하여 온도 80±2℃, 60rpm의 교반속도로 30분간 용해하는 제4단계;
상기 제4단계의 용해가 완료된 후, 정제수와 소듐클로라이드(Sodium Chloride)의 혼합물을 준비하고, 상기 혼합물을 투입하여 온도 80±2℃, 60rpm의 교반속도로 30분간 용해하는 제5단계;
상기 제5단계의 용해가 완료된 후, 용해물의 온도를 40±2℃가 되도록 냉각한 후, 항균제(Phytonside-HD)와 오가닉(Organic)혼합물과 보습제와 천연물 추출물 복합화합물로 이루어진 혼합물을 투입하여 온도 40±2℃, 60rpm의 교반속도로 30분간 용해하는 제6단계;
상기 제6단계의 용해가 완료된 후, 향료를 투입하여 패들믹서에서 50~60rpm의 교반속도로 10~20분간 교반혼합하고, 이후 호모믹서를 이용하여 2500~3500rpm으로 2~4분 교반한 후, 마이크로플로다이저(microfludizer)에서 700~1,000bar압력으로 3회 반복처리하는 제7단계를 포함하여 이루어지는 천연복합소재 추출물을 활용한 탈모예방 조성물의 제조방법.A first step of preparing a mixture of purified water and disodium EDTA, adding the mixture to an oil painting kiln and dissolving the mixture at a temperature of 80 ± 2 ° C and a stirring speed of 60 rpm for 30 minutes;
A second step of slowly adding guar hydroxypropyltrimonium chloride to the solution after the first step of dissolving the solution by heating, and dissolving the solution at a stirring rate of 60 캜 for 30 minutes at a temperature of 80 캜 and a temperature of 80 캜;
After the completion of the dissolution in the second step, Polyquaternium-10 is gradually added and dissolved at a temperature of 80 2 캜 and a stirring speed of 60 rpm for 30 minutes.
After the completion of the dissolution in the third step, a first mixture consisting of Citric Acid, Hydrogenated Polydecene and Dimethicone, and a mixture of purified water and dimethicone / vinyl dimethicone crosspolymer A second mixture consisting of Dimethicone / Vinyl Dimethicone Crosspolymer and C12-14 Pareth-12, glycol distearate, purified water, cocamidopropyl betaine, sodium A third mixture consisting of sodium chloride and a mixture of cocamide MEA and purified water and sodium laureth sulfate and citric acid and sodium carbonate, A fourth mixture, and a fifth mixture consisting of purified water and sodium laureth sulfate and phenoxyethanol were prepared, The resulting mixture was slowly added to the mixture, and the mixture was dissolved at a temperature of 80 캜 and a stirring speed of 60 rpm for 30 minutes.
After the completion of the dissolution in the fourth step, a mixture of purified water and sodium chloride is prepared, and the mixture is put in a fifth step of dissolving the mixture at a stirring rate of 60 ± 2 ° C for 30 minutes at a temperature of 80 ± 2 ° C.
After the dissolution in the fifth step is completed, the temperature of the melt is cooled to 40 ± 2 ° C., and a mixture of an antibacterial agent (Phytonside-HD) and an organic mixture, a humectant and a natural compound A sixth step of dissolving at a temperature of 40 2 캜 for 30 minutes at a stirring speed of 60 rpm;
After the completion of the dissolution in the sixth step, the perfume is added thereto, and the mixture is stirred in a paddle mixer at a stirring speed of 50 to 60 rpm for 10 to 20 minutes. Thereafter, the mixture is stirred at 2500 to 3500 rpm for 2 to 4 minutes using a homomixer, And a seventh step of repeating the treatment three times at a pressure of 700 to 1,000 bar in a microfludizer.
상기 제6단계의 혼합물은 항균제(Phytonside-HD)와 오가닉(Organic)혼합물과 보습제와 천연물 추출물 복합화합물의 혼합비율은 8:0.01:10:20의 중량비로 혼합한 혼합물인 것을 특징으로 하는 천연복합소재 추출물을 활용한 탈모예방 조성물의 제조방법.11. The method of claim 10,
Wherein the mixture of the sixth step is a mixture of a mixture of an antibacterial agent (Phytonside-HD) and an organic compound, a humectant and a complex compound of a natural product extract in a weight ratio of 8: 0.01: 10: A method for producing a composition for preventing hair loss using a material extract.
상기 제6단계의 혼합물을 구성하는 항균제는 벤질글라이콜(Benzyl Glycol)과 부톡시디글라이콜(Butoxydiglycol)과 라스베리케톤(Raspberry Ketone)을 혼합하여 이루어지며, 그 혼합비율은 0.6~0.7:0.1~0.11:0.03~0.035의 중량비로 혼합되는 것을 특징으로 하는 천연복합소재 추출물을 활용한 탈모예방 조성물의 제조방법.11. The method of claim 10,
The antibacterial agent constituting the mixture of step 6 is prepared by mixing Benzyl Glycol, Butoxydiglycol, and Raspberry Ketone, and the mixing ratio thereof is 0.6 to 0.7: 0.1 To 0.11: 0.03 to 0.035, based on the total weight of the composition.
상기 제6단계의 혼합물을 구성하는 오가닉(Organic)혼합물은 정제수, 부틸렌글라이콜(Butylene Glycol), 셀러리추출물, 쌀추출물, 양배추잎추출물, 순무잎추출물, 토마토열매 추출물, 당근추출물, 브로콜리추출물, 페녹시에탄올(phenoxyethanol), 에칠헥실글리세린을 혼합하여 이루어지는 것을 특징으로 하는 천연복합소재 추출물을 활용한 탈모예방 조성물의 제조방법.
11. The method of claim 10,
The organic mixture constituting the mixture of the sixth step may be purified water, butylene glycol, celery extract, rice extract, cabbage leaf extract, nettle leaf extract, tomato fruit extract, carrot extract, broccoli extract, Phenoxyethanol, and ethylhexyl glycerin. The method for preparing a composition for preventing hair loss,
상기 제6단계의 혼합물을 구성하는 보습제는 정제수, 소듐하이알루로네이트(Sodium Hyaluronate) 및 페녹시에탄올(phenoxyethanol)을 혼합하여 되며, 그 혼합량은 0.9~1.0:0.09~0.012:0.005~0.007의 중량비로 혼합한 것을 특징으로 하는 천연복합소재 추출물을 활용한 탈모예방 조성물의 제조방법.
11. The method of claim 10,
The moisturizing agent constituting the mixture of the sixth step is mixed with purified water, sodium hyaluronate, and phenoxyethanol, and the mixing ratio thereof is in the range of 0.9 to 1.0: 0.09 to 0.012: 0.005 to 0.007 And the mixture is mixed with the natural complex extract.
상기 제6단계의 혼합물을 구성하는 천연물 추출물 복합화합물은 산수유추출물; 구기자추출물; 산뽕나무잎추출물; 쌀겨추출물; 오미자추출물; 대추추출물; 녹차추출물; 감추출물; 은행잎추출물; 자소엽추출물; 귤껍질추출물; 더덕추출물; 큰조롱뿌리추출물; 인삼추출물; 길경추출물; 하수오추출물; 둥굴레추출물; 콩싹추출물; 가시오갈피뿌리추출물; 감초추출물; 청호추출물; 어성초추출물; 엉겅퀴꽃 추출물, 엉겅퀴잎 추출물 또는 엉겅퀴줄기추출물중 어느 하나의 추출물, 서양민들레추출물, 호스테일켈프추출물, 포공영추출물 및 정제수를 혼합하여 이루어지는 것을 특징으로 하는 천연복합소재 추출물을 활용한 탈모예방 조성물의 제조방법.
11. The method of claim 10,
The complex of natural extracts constituting the mixture of the sixth step is selected from the group consisting of corn oil extract; Gugija extract; Mulberry leaf extract; Rice bran extract; Omija extract; Jujube extract; Green tea extract; Persimmon extract; Ginkgo biloba extract; Leaf lobule extract; Tangerine peel extract; Roots extract; Large morsel root extract; Ginseng extract; Gakgyeong extract; Sashou Extract; Donguli extract; Sprout extract; Acanthopanax root extract; Licorice extract; Cheongho extract; Horsetail extract; A composition for preventing hair loss prevention using a natural complex material extract, which comprises a mixture of an extract of a thistle flower extract, a thistle leaf extract or a thistle stem extract, a dandelion dandelion extract, a horsetail kelp extract, a porpoise extract and purified water Way.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112805028A (en) * | 2018-07-27 | 2021-05-14 | 皮埃尔·法布尔皮肤化妆品公司 | Lespedeza capitata extract for hair care |
| KR20220052311A (en) * | 2022-03-30 | 2022-04-27 | 이명희 | Korean traditional herbs shampoo composition and manufacturing method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20100118364A (en) | 2009-04-28 | 2010-11-05 | 제주대학교 산학협력단 | Composition comprising the extract of acanthopanax koreanum nakai or the novel compound derived therefrom for preventing and treating baldness diseases |
| KR20140025068A (en) | 2012-08-21 | 2014-03-04 | 대전대학교 산학협력단 | Topical pharmaceutical composition and cosmetic composition comprising a herb extract as an active ingredient showing hair-growth stimulating activity and preventing activity from hair loss |
| KR20140098491A (en) | 2013-01-31 | 2014-08-08 | 박정숙 | Mixture extract of yacon(Smallanthus sonchifolius), Torilis japonica and Acorus gramineus, health food composition and cosmetic composition for preventing or improving benign prostatic hyperplasia or alopecia containing the same |
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2016
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20100118364A (en) | 2009-04-28 | 2010-11-05 | 제주대학교 산학협력단 | Composition comprising the extract of acanthopanax koreanum nakai or the novel compound derived therefrom for preventing and treating baldness diseases |
| KR20140025068A (en) | 2012-08-21 | 2014-03-04 | 대전대학교 산학협력단 | Topical pharmaceutical composition and cosmetic composition comprising a herb extract as an active ingredient showing hair-growth stimulating activity and preventing activity from hair loss |
| KR20140098491A (en) | 2013-01-31 | 2014-08-08 | 박정숙 | Mixture extract of yacon(Smallanthus sonchifolius), Torilis japonica and Acorus gramineus, health food composition and cosmetic composition for preventing or improving benign prostatic hyperplasia or alopecia containing the same |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112805028A (en) * | 2018-07-27 | 2021-05-14 | 皮埃尔·法布尔皮肤化妆品公司 | Lespedeza capitata extract for hair care |
| KR20220052311A (en) * | 2022-03-30 | 2022-04-27 | 이명희 | Korean traditional herbs shampoo composition and manufacturing method thereof |
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