KR20170087714A - Ultrasonic waves system for continuous monitoring of lung and method for monitoring - Google Patents

Ultrasonic waves system for continuous monitoring of lung and method for monitoring Download PDF

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Publication number
KR20170087714A
KR20170087714A KR1020160007631A KR20160007631A KR20170087714A KR 20170087714 A KR20170087714 A KR 20170087714A KR 1020160007631 A KR1020160007631 A KR 1020160007631A KR 20160007631 A KR20160007631 A KR 20160007631A KR 20170087714 A KR20170087714 A KR 20170087714A
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KR
South Korea
Prior art keywords
ultrasonic
lung
monitoring
server
ultrasound
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KR1020160007631A
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Korean (ko)
Inventor
권혁술
김규석
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서울대학교병원
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Priority to KR1020160007631A priority Critical patent/KR20170087714A/en
Priority to PCT/KR2016/006642 priority patent/WO2017126753A1/en
Publication of KR20170087714A publication Critical patent/KR20170087714A/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/08Detecting organic movements or changes, e.g. tumours, cysts, swellings
    • A61B8/0825Detecting organic movements or changes, e.g. tumours, cysts, swellings for diagnosis of the breast, e.g. mammography
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/08Detecting organic movements or changes, e.g. tumours, cysts, swellings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/52Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/5215Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data
    • A61B8/5223Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data for extracting a diagnostic or physiological parameter from medical diagnostic data
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/56Details of data transmission or power supply

Abstract

The present invention relates to an ultrasonic system and a monitoring method for continuous monitoring of a lung state, including a small-sized ultrasonic probe attached to a chest; An ultrasonic monitoring device connected to the ultrasonic probe; And a server connected to the ultrasonic monitoring apparatus, wherein the B-line of the lung is measured by the ultrasonic probe and the ultrasonic monitoring apparatus, and the gray scale image is transmitted to the server, The scoring is transmitted to the monitor of the ultrasonic monitoring device in real time, and the lung state of the serious patient can be observed in real time, so that it is possible to take prompt action.

Description

[0001] Ultrasonic systems and monitoring methods for continuous monitoring of lung conditions [

The present invention relates to an ultrasound system and a monitoring method for continuous monitoring of a lung state. More particularly, the present invention relates to an ultrasound system and a monitoring method for monitoring continuous pulmonary status of a lung by using a small ultrasonic probe, scoring gray scale images of lungs by ultrasound, To an ultrasonic system and a monitoring method for continuously monitoring the lung state.

In patients admitted to the ICU, the status of the lung is closely related to the survival rate, intensive care unit room length, and medical expenses, so it is important to observe and confirm the status of the lung. Ultrasonography is now becoming a basic tool for understanding cardiopulmonary status in the ICU. Echocardiography can be used to identify the condition of the heart and to confirm hemodynamic status. Pulmonary congestion, pneumothorax, acute respiratory distress syndrome (ARDS), etc., The importance of which is increasing, and its accuracy and reliability are intended to precede chest radiography.

Normal lungs signal A-line and lung sliding. However, pulmonary congestion or pulmonary ultrasound is a sign of the B-line, showing the echogenicity of the nodule as the interlobular septa becomes thicker due to edema of the lungs (Noble VE, Nelson B. Manual of Emergency and Critical Care Ultrasound. 2nd ed. Cambridge, England: Cambridge University Press; 2011)

Most of the signals observed in these ultrasonic waves depend on the operator. The same is true for B-line signals, and a method for measuring the degree of B-line directly in an ultrasonic machine has been studied. Brattain LJ, Telfer BA, Liteplo AS, Noble VE. Automated B-line scoring on thoracic sonography. J Ultrasound Med. Dec 31 (12): 2185-90. PubMed PMID: 24277902.)

In the initial study of pulmonary ultrasound, it was reported that a minimum of 12 pulmonary sites should be measured to determine the exact state of the lung. However, recent studies have shown that pulmonary ultrasound in confined areas does not have any problem in accurately measuring lung status (Brattain LJ, Telfer BA, Liteplo AS, Noble VE, Automated B-line scoring on thoracic sonography, J Ultrasound Med., 2013 Dec; 32 (12): 2185-90 PubMed PMID: 24277902.)

In addition, a scoring system was developed to quantify the degree of B-line showing pulmonary congestion in pulmonary ultrasound. The higher the score, the less prognosis the patient had (Santos TM, Franci D, Coutinho CMG, Ribeiro DL, Schweller M, Matos-Souza JR, et al. A simplified ultrasound-based edema score to assess lung injury and clinical severity in septic patients. Am J Emerg Med 2013; 31 (12): 1656-60 PubMed PMID: 24119611. PMCID: 24119611.)

However, in order to observe pulmonary congestion or pulmonary status by ultrasound, a large-sized ultrasonic machine should be brought to the side of the patient's bed, and in the case of the ICU, it may be difficult to perform in a narrow ICU space. In addition, although the pulmonary status of an ICU changes in real time, currently, pulmonary status is confirmed after a pulmonary ultrasound is taken only at a specific time. There is no system for monitoring the pulmonary status in real time, and the problem that the reading of ultrasound results varies depending on the skill of an observer have.

Korean Patent Publication No. 10-1159209 Japanese Patent Laid-Open Publication No. 2013-515592

SUMMARY OF THE INVENTION The present invention has been made in order to solve all of the above problems, and it is an object of the present invention to transmit a gray scale image according to a B-line of a lung photographed by ultrasonic waves to a server in real time by attaching a small ultrasonic probe to the chest. And an ultrasonic system in which the server processes the image and scorens a score to the monitor in real time to continuously monitor the lung state.

Another object of the present invention is to provide a monitoring method for acquiring a gray-scale image according to the B-line using ultrasonic waves of the ultrasonic probe, displaying the score obtained by scaling the scale image, and continuously monitoring the lung.

In order to accomplish the above object, an ultrasonic system for continuous monitoring of the lung state of the present invention comprises: a small ultrasonic probe attached to the chest; An ultrasonic monitoring device connected to the ultrasonic probe; And a server connected to the ultrasonic monitoring apparatus, wherein the B-line of the lung is measured by the ultrasonic probe and the ultrasonic monitoring apparatus, and the gray scale image is transmitted to the server, And the scoring is transmitted to the monitor of the ultrasonic monitoring device in real time.

It is also desirable to further include a software program embedded in the server for measuring and scaling the gray scale of the B-line of the pulmonary ultrasonic wave by the ultrasonic probe and calculating a change over a period of time.

The ultrasonic monitoring device and the server are preferably connected to each other by wireless or wire.

A method for continuously monitoring a lung state includes the steps of attaching an ultrasonic probe to a chest and emitting an ultrasonic wave to acquire a lung image; Confirming the presence of the B-line in the acquired lung image; Scoring a gray scale of the lung image when the B-line is present; And displaying the score by the scoring.

It is preferable that the ultrasonic emission and the display of the score are performed by an ultrasonic monitoring apparatus including a monitor.

According to the ultrasound system for continuous monitoring of the pulmonary condition of the present invention, when the present invention is successfully performed, it is possible to observe the pulmonary state in real time, which can significantly help the treatment of serious diseases, One piece of data can be used as a basis for important studies of biomechanics such as cardiovascular circulation model and lung mechanics.

In clinical medicine, it is expected that it will be an important starting point of research on personalization / automation of optimal treatment guidelines based on real - time lung condition in other fields besides ICU if it leads to clinical studies in the future.

In addition, it is possible to observe the pulmonary status non-invasively in real-time in a completely different way from the current monolithic treatment method in the treatment of an infected ICU, so that treatment according to the individual's lung condition becomes possible, , It is possible to establish new guidelines for the treatment of ICU and to lead internationally leading clinical studies.

In addition, from the socio-economic point of view, the industrial / economic impact is expected to be very large when considering the wide range of ICU market worldwide due to the ultrasonic system that continuously monitors the lung status.

1 is a schematic configuration diagram of an ultrasonic system for continuously monitoring the lung state according to the present invention
Fig. 2 shows an ultrasound image showing the pulmonary state observed by the ultrasound
FIG. 3 is a flowchart of a processing model using an ultrasonic system for continuously monitoring the lung state according to the present invention
4 is a flowchart showing a lung ultrasound monitoring algorithm according to the present invention.

Hereinafter, preferred embodiments of an ultrasonic system and a monitoring method for continuous monitoring of a lung state according to the present invention will be described in detail with reference to the accompanying drawings. It is to be understood that the present invention is not limited to the disclosed embodiments, but may be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete, It is provided to inform.

The ultrasound system of the present invention is configured with an ultrasonic monitoring device and a server so that a small ultrasonic probe such as an electrocardiogram (ECG) or a blood oxygen saturation (SpO2) monitoring device is attached to the chest to constantly observe the state of the lung .

In other words, by monitoring the pulmonary status by ultrasound in real time, it is possible to cope with the change of blood test, chest X-ray and SpO2 more rapidly in pulmonary edema or ARDS of severe patient .

Accordingly, in the ultrasound system of the present invention, a gray scale image according to the B-line observed with pulmonary ultrasound is scored or scored by a server to which an ultrasonic apparatus or an ultrasonic monitoring apparatus is connected, rather than an observer, Information that can monitor the score according to the scoring in real time can be provided so that an immediate action can be taken. As a result, the ultrasound system of the present invention can increase the survival rate of patients admitted to the ICU, and reduce the hospital stay, thereby reducing medical expenses.

1 is a schematic block diagram of an ultrasound system for continuously monitoring a lung state according to the present invention.

1, the ultrasonic system for continuously monitoring the lung state according to the present invention includes an ultrasonic monitoring device 3 including an ultrasonic probe 1 and a monitor 2, and a server (not shown) .

The ultrasonic transducer 1 is designed to be light and small so that it does not interfere with breathing even if it is affixed to the patient's chest and is small and light enough not to increase the work of breathing even when there is spontaneous breathing or artificial breathing It is easy to attach and detach.

The ultrasonic monitoring apparatus 3 includes a monitor 2 connected to the ultrasonic probe 1 to emit ultrasonic waves through the probe 1 and capable of displaying an image of a lung photographed by ultrasonic waves .

The server may be connected to the ultrasonic probe 1 and the ultrasonic monitoring device 3 either wirelessly or in a wire manner and may be connected to the ultrasonic probe 1 and the ultrasonic monitoring device 3 in a gray scale ) Images to be centrally stored and processed separately.

Hereinafter, the process of observing the lung state in real time using the ultrasonic probe 1, the ultrasonic monitoring apparatus 3, and the server will be described.

2 is an ultrasound image showing a lung state observed with an ultrasonic wave.

As shown in FIG. 2, when pulmonary edema or acute respiratory distress syndrome (ARDS) progresses, a B-line is generated in the pulmonary ultrasound image. As the condition deteriorates, the number of B-lines increases The gray scale goes up. When the absolute value of the gray scale of the gray scale zone except for the pleural zone of the image of FIG. 3 is measured and the change is shown, pulmonary edema or acute respiratory distress syndrome (ARDS) Can be known and coped with in real time faster than chest X-ray.

Since a separate software program is needed to measure the absolute value of the B-line grayscale image of the pulmonary ultrasound observed with ultrasonic waves and calculate the change over a certain period of time after scoring it, that is, scoring it, Embedded in the server. In the process of measuring and calculating the gray-scale image, there is a limitation only by the ultrasonic monitoring device. As described above, the calculation algorithm of the scoring system performed by the server and the server connected to the ultrasonic monitoring device wirelessly or by wire, Software program.

The ultrasound system for continuous monitoring of the pulmonary condition according to the present invention as described above requires preclinical experiments through experiments of large animals such as pigs.

The method of monitoring the lung state in real time by the pulmonary ultrasonic wave is as follows. First, an ultrasonic probe is attached to both lung parts to measure the gray scale of the B-line of the lung, and the gray scale according to the measured B- And transmits the image to the server connected to the ultrasonic monitoring device in real time. Then, the B-line grayscale image is stored in the server and scored by the server, and the ultrasound score of the lung scored on the monitor of the ultrasonic monitoring apparatus is transmitted in real time.

FIG. 3 is a flowchart of a processing model using an ultrasonic system for continuously monitoring the lung state according to the present invention.

As shown in FIG. 3, ultrasound images are scored and analyzed in pulmonary conditions such as pulmonary edema, fluid status, and pneumothorax by continuously emitting ultrasound to the lungs through an ultrasonic probe, The ultrasound system is operated to monitor and monitor the fluid status to adjust the fluid status processing under the condition of the above-described condition, and then the continuous ultrasonic wave is repeatedly emitted to the lung site through the ultrasonic probe. That is, by repeating this process, the lung state according to the ultrasound image can be monitored in real time.

4 is a flowchart illustrating a lung ultrasound monitoring algorithm according to the present invention.

As shown in FIG. 4, the algorithm of the software program for monitoring the pulmonary ultrasonic wave according to the present invention is as follows.

The ultrasonic transducer is connected to the anterior axillary line between the anterior axillary line and the mild clavicle line. The ultrasonic transducer is attached to the chest of the mid- Place it in the fourth intercostal space.

When the ultrasonic probe is installed and positioned, the ultrasonic probe measures a gray scale at a depth of 3 to 5 cm and transmits a gray scale value to a monitor and analyzer body, Display.

Check for a sudden change in the score displayed on the monitor, and if there is no change, provide the monitor with a continuous display of the score to provide information about the state of the screen. If there is a change, operate the alarm system to determine whether the score is increasing or decreasing.

If there is a decrease in the score, check whether there is a pneumothorax or ultrasonic probe dropout, and if there is an increase in the score, judge whether the lung congestion or acute respiratory failure is progressing.

A method for continuously monitoring the pulmonary condition by the ultrasonic system of the present invention based on the peculiar monitoring algorithm is as follows.

First, an ultrasonic probe is attached to the chest, and ultrasound is emitted from the ultrasonic probe through an ultrasonic monitoring device to acquire a lung image.

Next, the presence of a B-line for judging the presence or absence of an abnormality in lung is confirmed from the obtained lung image.

Next, when the B-line exists, the gray scale of the lung image is scored by a software program built in the ultrasonic monitoring apparatus to calculate a certain score.

Next, the score calculated by the scoring is displayed on a monitor included in the ultrasonic monitoring device to check the status of the lung in real time.

As described above, the ultrasound system and the monitoring method for continuous monitoring of the lung state according to the present invention have been described with reference to the drawings. However, the present invention is not limited to the embodiments and the drawings disclosed herein, It is needless to say that various modifications can be made by those skilled in the art within the scope of the technical idea of the invention.

1: Ultrasonic probe 2: Monitor
3: Ultrasonic monitoring device

Claims (5)

A small ultrasonic probe attached to the chest;
An ultrasonic monitoring device connected to the ultrasonic probe; And
And a server connected to the ultrasonic monitoring device,
The B-line of the lung is measured by the ultrasonic probe and the ultrasonic monitoring device, and a gray scale image according to the B-line is transmitted to the server, and scoring according to the gray scale image stored in the server is transmitted to the monitor of the ultrasonic monitoring device in real time And an ultrasound system for continuous monitoring of the pulmonary condition.
The method according to claim 1,
Further comprising a software program embedded in the server to measure and scale the B-line gray scale of the pulmonary ultrasound wave by the ultrasonic probe and to calculate a change over a period of time. system.
The method according to claim 1,
Wherein the ultrasonic monitoring device and the server are connected to each other in a wireless or wired manner.
A method for continuously monitoring lung conditions,
Attaching an ultrasonic probe to the chest and emitting ultrasound to acquire a lung image;
Confirming the presence of the B-line in the acquired lung image;
Scoring a gray scale of the lung image when the B-line is present; And
And displaying a score by the scoring. ≪ Desc / Clms Page number 19 >
5. The method of claim 4,
Wherein the ultrasound emission and the display of the score are performed by an ultrasonic monitoring apparatus including a monitor.
KR1020160007631A 2016-01-21 2016-01-21 Ultrasonic waves system for continuous monitoring of lung and method for monitoring KR20170087714A (en)

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KR1020160007631A KR20170087714A (en) 2016-01-21 2016-01-21 Ultrasonic waves system for continuous monitoring of lung and method for monitoring
PCT/KR2016/006642 WO2017126753A1 (en) 2016-01-21 2016-06-23 Ultrasound system and monitoring method for continuous monitoring of state of the lungs

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EP3713497A1 (en) * 2017-11-22 2020-09-30 Koninklijke Philips N.V. Ultrasonic pulmonary assessment
JP6944087B2 (en) * 2018-07-27 2021-10-06 コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. Lung pulse detectors, systems, and methods in ultrasound
WO2021205214A1 (en) 2020-04-09 2021-10-14 Modi Vivendi As System for the removal of alveolar (thorax) fluids in patients with infectious and/or virus diseases (covid-19)
EP4202949A1 (en) * 2021-12-23 2023-06-28 Koninklijke Philips N.V. Methods and systems for clinical scoring of a lung ultrasound
WO2023117785A1 (en) * 2021-12-23 2023-06-29 Koninklijke Philips N.V. Methods and systems for clinical scoring of a lung ultrasound
CN116188499B (en) * 2023-05-04 2023-06-30 北京易优联科技有限公司 Segmentation method for lung ultrasonic image

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US8221323B2 (en) * 2007-08-03 2012-07-17 Cardiac Pacemakers, Inc. Using acoustic energy to compute a lung edema fluid status indication
EP2806802A1 (en) * 2012-01-26 2014-12-03 Yoram Palti Diagnosing lung disease using transthoracic pulmonary doppler ultrasound during lung vibration
WO2013181300A1 (en) * 2012-05-29 2013-12-05 The Board Of Trustees Of The Leland Stanford Jr. University Apparatus, systems, and methods for monitoring extravascular lung water
HRPK20130491B3 (en) * 2013-06-04 2016-03-25 Sveučilište U Rijeci Medicinski Fakultet Method for determining and counting b-lines in ultrasonic diagnoses of lung disease
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