KR20160135604A - bag for fat separation - Google Patents

bag for fat separation Download PDF

Info

Publication number
KR20160135604A
KR20160135604A KR1020150069178A KR20150069178A KR20160135604A KR 20160135604 A KR20160135604 A KR 20160135604A KR 1020150069178 A KR1020150069178 A KR 1020150069178A KR 20150069178 A KR20150069178 A KR 20150069178A KR 20160135604 A KR20160135604 A KR 20160135604A
Authority
KR
South Korea
Prior art keywords
fat
space
tissue
separation membrane
separation
Prior art date
Application number
KR1020150069178A
Other languages
Korean (ko)
Inventor
장영진
Original Assignee
주식회사 엔씨테크론
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 주식회사 엔씨테크론 filed Critical 주식회사 엔씨테크론
Priority to KR1020150069178A priority Critical patent/KR20160135604A/en
Publication of KR20160135604A publication Critical patent/KR20160135604A/en

Links

Images

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D17/00Separation of liquids, not provided for elsewhere, e.g. by thermal diffusion
    • B01D17/08Thickening liquid suspensions by filtration
    • B01D17/085Thickening liquid suspensions by filtration with membranes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/10Bag-type containers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/1475Inlet or outlet ports
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D2221/00Applications of separation devices
    • B01D2221/10Separation devices for use in medical, pharmaceutical or laboratory applications, e.g. separating amalgam from dental treatment residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Thermal Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • External Artificial Organs (AREA)

Abstract

TECHNICAL FIELD The present invention relates to a fat separation container, and more particularly, to a fat separation container capable of separating and purifying impurities other than fat from fat tissue obtained from a living body.
The fat separation container of the present invention comprises: a storage bag formed by joining edges of a front sheet and a rear sheet opposite to each other; a first space portion provided between the front sheet and the back sheet, And a plate-like spacing member provided in the second space and spaced apart from the separation membrane and the rear sheet, wherein the plate-shaped spacing member is disposed at a lower end of the first space, The lower end of the second space portion is formed at a lower position.

Description

BACKGROUND OF THE INVENTION [0001]

TECHNICAL FIELD The present invention relates to a fat separation container, and more particularly, to a fat separation container capable of separating and purifying impurities other than fat from fat tissue obtained from a living body.

Generally, implantation of implants and autologous fat injection are used for enlargement such as breast enlargement, facial molding (nose, chin, ball, etc.).

Injection of implants is easy to control the size and can be done at once. However, because it is inserted into the body, it is not clinically safe, and the feeling and feeling are not good. On the other hand, autologous fat injection sucks the remaining fat Because it is re-infused with poor chest, heap, face, etc., removal of unnecessary part and enlargement of poor part are done, so body balance is made and self-fat is injected directly, so there is no resistance to foreign substances and texture There is an advantage of feeling good.

However, in the case of autologous fat injection, the fat survival rate is extremely low to 20 to 50%, which is not enough to obtain the desired size. In order to obtain the desired size, 2 to 3 procedures are required, There is a problem. Therefore, various attempts have been made to increase the fat survival rate. As a result of clinical trials, the survival rate was improved by injecting only pure fat.

When the fat is inhaled from the human body, impurities such as blood, body fluids, aging cells and the like are sucked together as well as fat, so that a centrifuge can be used as a method for removing impurities and separating pure fat.

Autologous fat injection using a centrifuge is largely made up of liposuction, centrifugation, and fat infusion. Liposuction is usually performed by aspirating the suction bottle into a vacuum to inhale the fat, and centrifugation to make pure fat Separate centrifuges are used. In order to inject the fat that has undergone the centrifugation process into the body implantation site, it is common to inject the fat directly by hand using a syringe.

However, the centrifugal separation method for separating and purifying fat has a problem that it is merely for the purpose of removing moisture, and it is impossible to select cells, and the fat cells are liable to be damaged by the pressure of the centrifugal separator.

In order to solve such a problem, Korean Patent Publication No. 2014-0060843 discloses a fat tissue concentration system.

The above-mentioned fat tissue concentration system uses a filtration type filter bag instead of a centrifugal separation method in order to separate and purify pure fat from a fat tissue (untreated fat tissue) extracted from a human body and containing various impurities. The filter bag has a structure in which two filters, that is, a tissue filter 101 and an inner complement filter 102, are provided between the two PVC films 100 and 103 as shown in Fig. The tissue filter is for filtering adipocytes with a pore size of 50 mu m to 300 mu m and the internal complement filter is a porous polymeric surface membrane having a pore size of 100 mu m to 2000 mu m. The internal complementary filter is configured to minimize contact between tissue filter 101 and PVC films 100 and 103 thereby preventing tissue filter 101 and PVC films 100 and 103 from adhering to each other during tissue processing.

The filter bag is divided into two spaces 201 and 202 by a tissue filter 101 existing between the PVC films 100 and 103 as shown in FIG. When the untreated fat tissue injected into the first space 202 belonging to the upper part of the tissue filter 101 through the tissue port 106 provided in the filter bag passes through the tissue filter 101, Only the blood cells, the free fat, the Tumescent solution and other impurities can move to the second space 201 belonging to the lower part of the tissue filter 101, and the stem cells and the pure adipocytes can move to the first space 202 .

The inside of the above-described conventional filter bag is simply shown in Fig. The conventional filter bag is divided into the first and second spaces 201 and 202 by the tissue filter 101 existing between the two PVC films 100 and 103. The bottom of the first space And the bottom of the second space (lower end of the second space) are formed at the same height. Therefore, when the amount of untreated fat tissue contained in the first space is small, there is a problem that impurities are separated and it is difficult to move to the second space.

Further, the tissue filter provided inside the filter bag has a problem in that the surface area is relatively small because both surfaces are formed flat. In addition, since both sides of the internal complementary filter located between the PVC film and the tissue filter are flat and wide, both sides of the internal complementary filter easily stick to the PVC film and the tissue filter.

Korean Patent Publication No. 2014-0060843: Fatty tissue concentration system

SUMMARY OF THE INVENTION The present invention has been made to overcome the above-mentioned problems, and it is an object of the present invention to provide a method of manufacturing a semiconductor device having a first space portion into which an untreated fat tissue containing impurities is introduced and a second space portion into which impurities separated from the untreated fat tissue are introduced, And it is an object of the present invention to provide a fat separation vessel which can improve the separation effect.

To achieve the above object, according to the present invention, there is provided a fat separation container comprising: a storage bag formed by joining edges of a front sheet and a rear sheet facing each other; A separation membrane installed between the front sheet and the back sheet to divide the inside of the storage bag into a first space part through which untreated fat tissue flows and a second space part through which impurities separated from the untreated fat tissue are introduced; And a plate-shaped spacing member provided in the second space to separate the separation membrane from the back sheet, wherein a lower end of the second space is formed at a lower position than a lower end of the first space.

A plurality of first projections are formed on one surface or both surfaces of the separation membrane.

The first protrusions are formed to protrude into an arcuate shape.

A plurality of second projections are formed on one surface or both surfaces of the spacer.

The second protrusion is formed so as to protrude convexly in an arcuate shape.

As described above, according to the present invention, the first space portion into which the untreated fat tissue containing impurities is introduced and the second space portion into which the impurities separated from the untreated fat tissue are introduced are formed differently to improve the separation effect of impurities .

Further, since the first protrusions are formed in the separation membrane, the surface area of the separation membrane can be widened, and the effect of separating the impurities can be enhanced. Further, the second protrusions may be formed on the surface of the spacing member to reduce sticking of the back sheet and the separating film to both sides of the spacing member.

1 is a perspective view of a fat separation vessel according to an embodiment of the present invention,
Fig. 2 is an exploded perspective view of Fig. 1,
Fig. 3 is an exploded perspective view of Fig. 1,
Fig. 4 is a longitudinal sectional view of Fig. 1,
5 is a perspective view of a separation membrane according to another embodiment of the present invention,
6 is a perspective view of a spacing member applied to another embodiment of the present invention,
FIG. 7 is a longitudinal sectional view of the present invention to which FIG. 5 and FIG. 6 are applied,
FIG. 8 is a cross-sectional view of the present invention to which FIG. 5 and FIG. 6 are applied,
FIG. 9 is an exploded perspective view of a filter bag according to a conventional technique,
Fig. 10 is a perspective view of Fig. 9,
11 is a longitudinal sectional view of Fig.

Hereinafter, a fat separation vessel according to a preferred embodiment of the present invention will be described in detail with reference to the accompanying drawings.

1 to 4, the fat separation vessel of the present invention mainly includes a storage bag 10, a separation membrane 30, and a spacing member 40.

The storage bag 10 is in the form of a bag having a closed space formed therein. On the upper portion of the storage bag 10, a hooking hole 5 may be formed so as to be hooked on a cradle. In the lower part of the storage bag 10, a plurality of ports are provided for inflow and discharge of contents. For example, a liposuction port 21 into which a fat tissue (hereinafter referred to as untreated fat tissue) extracted from a human body and containing various impurities is introduced, a fat discharge port 23 through which pure fat tissue from which impurities have been removed, An impurity exhaust port 25 through which impurities separated from adipose tissue are discharged can be provided. The ports are designed as check valves so that the contents can be prevented from leaking in the reverse direction.

In the present invention, 'adipose tissue' is a connective tissue composed of adipocytes and fibers. Adipose cells are usually spherical, 50 ~ 100um larger than normal cells, and each adipocyte is wrapped with fibers and capillaries are distributed at high density between cells. These adipose tissues are found in the subcutaneous, major retina, and mesentery, especially in the kidney, heart surface, joints, and iliac bone. They are used not only as a storage nutrient but also as an energy source and prevent heat loss. . In addition, it has the function of filling spaces between tissues and supporting structures such as blood vessels and nerves. The term " untreated adipose tissue " refers to an adipose tissue extracted from the inside of the human body and containing impurities such as blood, body fluids, aging cells and the like.

The storage bag 10 can be formed by joining edges with two sheets facing each other. For example, the edges of the front sheet 11 and the back sheet 15 facing each other may be joined together by a heat fusion method to form the storage bag 10.

The front sheet 11 and the back sheet 15 may be formed of any one material selected from medical grade polyvinyl chloride, polyester, nylon and polypropylene.

The separation membrane 30 is installed inside the storage bag 10 to separate impurities from untreated fat tissue. The separation membrane 30 is installed between the front sheet 11 and the back sheet 15 and divides the inside of the storage bag 10 into two spaces. That is, the first space portion 35 into which the untreated adipose tissue is introduced and the second space portion 37 into which the impurities separated from the untreated adipose tissue flow are partitioned. The first space portion 35 is located between the front sheet 11 and the separation membrane 30 and the second space portion 37 is located between the separation membrane 30 and the rear sheet 15. [ The edge of the separator 30 may be located between the front sheet 11 and the back sheet 15.

The fat infusion port 21 and the fat discharge port 23 described above are connected to the first space portion 35 and the impurity outlet port 25 is connected to the second space portion 37.

The separation membrane (30) has a filter structure with innumerable pores. The pore size of the separation membrane 30 may be 50 탆 to 300 탆. If the pore size of the separation membrane 30 is smaller than 50 탆, impurities do not pass through the separation membrane, and it is difficult to separate only pure fat cells. When the pore size is larger than 300 탆, pure fat cells can pass through the separation membrane.

The spacing member (40) is provided in the second space portion (37). The spacing member 40 is in the form of a thin plate. The spacing member 40 separates the separating film 30 and the back sheet 15 from each other. This spacing member 40 minimizes the contact between the separator 30 and the backsheet 15 thereby preventing the separator 30 and the backsheet 15 from adhering to each other in the separation assumption of adipose tissue.

The spacing member 40 may be one selected from polyester, nylon, and polypropylene, and the spacing member 40 may include, but is not necessarily limited to, a porous polymeric surface film, a lipid adsorption screen, or a polyester mesh screen . The spacing member 40 may be a porous polymer sheet having a pore size of 100 mu m to 2000 mu m. The pore size of the spacing member (40) may be larger than the pore size of the separation membrane (30).

The fat separation process will be briefly described using the above-described fat separation vessel.

The untreated fat tissue extracted from the living body by the inhalation fat molding, the ultrasonic wave liposuction, the resection fat removal, the laser fat molding, the water injection fat molding and the like are contained in the syringe. The untreated fat tissue contained in the syringe is injected into the first space portion 35 of the storage bag 10 through the fat injection port 21. Impurities such as blood, moisture, cleaning solution and the like in the untreated fat tissue injected into the first space part 35 pass through the separation membrane 30 and are moved to the second space part 37. In the first space part 35, Only pure fat tissue remains. Thereafter, the impurities stored in the second space portion 37 are discharged to the outside through the impurity discharge port 25 and stored in the drain bag. The pure fatty tissue remaining in the first space part (35) can be discharged to the outside through the fat discharge port (23). The pure adipose tissue excreted to the outside can be injected into a part of the human body that has been cut for autotransplantation.

On the other hand, the liposuction port 21 can be used for injecting the washing liquid into the first space portion 35. A physiological washing solution such as a Ringer's solution or saline can be used as the washing solution. The washing solution is intended for washing fat tissue. The storage bag may be agitated to facilitate separation of the free lipid, erythrocyte, leukocyte, etc. from the adipose tissue after infusion of the wash solution.

4, the lower end B of the second space 37 is positioned at a lower position than the lower end A of the first space 35, do. This is to allow the impurities to be easily separated even when the amount of untreated fat tissue contained in the first space portion 35 is small. Since the first space portion 35 is located at a higher position than the second space portion 37, the separation membrane permeation pressure of the impurities becomes higher, so that the impurities can be easily separated.

Meanwhile, in the fat separation vessel according to another embodiment of the present invention, the separation membrane may be embossed to form first protrusions on the surface.

Referring to FIG. 5, a plurality of first projections 55 are formed on both front and rear surfaces of the separation membrane 50 at a predetermined interval. Needless to say, the first protrusions may be formed only on one side of the separator 50. The first projections 55 are formed in alignment with the longitudinal direction. In the illustrated example, the first protrusions 55 are formed so as to protrude into an arc shape.

Since the plurality of first protrusions 55 are formed on the surface of the separation membrane 50, the surface area of the separation membrane 50 can be maximized. Therefore, the impurity separation effect can be enhanced.

In another embodiment of the present invention, the fat separation vessel according to the embodiment may be formed by embossing the spacers to form second projections on the surface.

Referring to FIG. 6, a plurality of second projections 65 are formed on both front and rear surfaces of the spacing member 60 at predetermined intervals. Needless to say, the second projections may be formed only on one surface of the spacer 60. The second projections (65) are formed in alignment with the longitudinal direction. In the illustrated example, the second projection 65 is formed so as to protrude in an arcuate shape.

As described above, since the second protrusions 65 are formed on the surface of the spacer member, the area of contact between the both surfaces of the spacer member 60 and the separator or the backsheet can be reduced. Therefore, even if both surfaces of the spacing member adhere to the back sheet and the separator, they can be easily dropped.

7 and 8 show the inside of the fat separation vessel to which the separation membrane and the separation member described above are applied.

Referring to FIGS. 7 and 8, first protrusions 55 are formed on both sides of the separation membrane 50, and second protrusions 65 are formed on both sides of the separation member 60.

The first protrusions 55 of the separation membrane 50 and the second protrusions 65 of the spacer 60 are staggered from each other. In other words, the second protrusions 65 are positioned between the first protrusions 55 and the first protrusions 55 are positioned between the second protrusions 65 in a corresponding manner.

The components not described above are the same as the embodiment of Fig.

While the present invention has been particularly shown and described with reference to exemplary embodiments thereof, it is evident that many alternatives, modifications and variations will be apparent to those skilled in the art. Accordingly, the true scope of protection of the present invention should be determined only by the appended claims.

10: Storage bag 11: Front sheet
15: backside seeking 21: fat injection port
23: local exhaust port 25: impurity exhaust port
30: separator 35: first space part
37: second space part 40: spacing member

Claims (5)

A storage bag formed by joining the edges of the front and back sheets facing each other;
A separation membrane installed between the front sheet and the back sheet to divide the inside of the storage bag into a first space part through which untreated fat tissue flows and a second space part through which impurities separated from the untreated fat tissue are introduced;
And a plate-like spacing member provided in the second space portion to separate the separation membrane from the back sheet,
And the lower end of the second space is formed at a lower position than the lower end of the first space.
The fat separation vessel according to claim 1, wherein a plurality of first projections are formed on one or both sides of the separation membrane. The fat separation container according to claim 2, wherein the first projections are formed to protrude convexly in an arcuate shape. 2. The fat separation container according to claim 1, wherein a plurality of second projections are formed on one or both sides of the spacer. 5. The fat separation container according to claim 4, wherein the second protrusions are convexly protruded in an arcuate shape.
KR1020150069178A 2015-05-18 2015-05-18 bag for fat separation KR20160135604A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020150069178A KR20160135604A (en) 2015-05-18 2015-05-18 bag for fat separation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020150069178A KR20160135604A (en) 2015-05-18 2015-05-18 bag for fat separation

Publications (1)

Publication Number Publication Date
KR20160135604A true KR20160135604A (en) 2016-11-28

Family

ID=57706957

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020150069178A KR20160135604A (en) 2015-05-18 2015-05-18 bag for fat separation

Country Status (1)

Country Link
KR (1) KR20160135604A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20180113405A (en) * 2017-04-06 2018-10-16 김태영 Kit for extracting device of regenerative cells

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20180113405A (en) * 2017-04-06 2018-10-16 김태영 Kit for extracting device of regenerative cells

Similar Documents

Publication Publication Date Title
DK175916B1 (en) System and method for treating biological fluids
JP6469123B2 (en) Hollow fiber membrane type body fluid filtration device, operation method and filtration method of hollow fiber membrane type body fluid filtration device
KR101099962B1 (en) Fluid distribution module and extracorporeal blood circuit including such a module
EP0591980A2 (en) Leukocyte-removing filter device and system
JP3012689B2 (en) Autologous blood collection membrane system and method
ES2791528T3 (en) Air trap and microbubble removal systems from a fluid stream
ES2464990T5 (en) Blood recovery device and method
US20150202418A1 (en) Microneedle-based devices and methods for the removal of fluid from a body
JP2007014620A (en) Circuit and apparatus for blood component collection
JP2000512173A (en) Blood processing system
US20150352266A1 (en) Fat processing device
WO2016067946A1 (en) Method for priming hollow-fiber membrane module
EP2843035A1 (en) Nucleated-cell capturing filter and nucleated-cell preparation method using same
JP2021509351A (en) Systems and methods for processing blood outflows for autotransfusion
KR20160135604A (en) bag for fat separation
AU2015299007B2 (en) Filter module
JP2918595B2 (en) White blood cell separator
US11911549B2 (en) Plasmapheresis device
JP2006158738A (en) Centrifugal method of leukoreduction system
KR102030028B1 (en) Fat purification system
WO2019059279A1 (en) Device, system and method for preparing cell suspension
ES2953615T3 (en) Hemorrhagic fluid treatment system and procedure for autotransfusion
WO2017179705A1 (en) Container for cell suspension preparation, and preparation method for cell suspension
Fourtounas Cell saver physics–a review
US20230173147A1 (en) Blood separation system and blood products

Legal Events

Date Code Title Description
A201 Request for examination
E902 Notification of reason for refusal
E902 Notification of reason for refusal
E701 Decision to grant or registration of patent right