KR20160111693A - strip for inspecting reaction, inspection apparatus of strip - Google Patents
strip for inspecting reaction, inspection apparatus of strip Download PDFInfo
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- KR20160111693A KR20160111693A KR1020150036679A KR20150036679A KR20160111693A KR 20160111693 A KR20160111693 A KR 20160111693A KR 1020150036679 A KR1020150036679 A KR 1020150036679A KR 20150036679 A KR20150036679 A KR 20150036679A KR 20160111693 A KR20160111693 A KR 20160111693A
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- reaction
- strip
- pattern
- inspection
- position information
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/493—Physical analysis of biological material of liquid biological material urine
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54306—Solid-phase reaction mechanisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
- G01N35/1011—Control of the position or alignment of the transfer device
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06K—GRAPHICAL DATA READING; PRESENTATION OF DATA; RECORD CARRIERS; HANDLING RECORD CARRIERS
- G06K7/00—Methods or arrangements for sensing record carriers, e.g. for reading patterns
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T7/00—Image analysis
- G06T7/0002—Inspection of images, e.g. flaw detection
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Theoretical Computer Science (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Quality & Reliability (AREA)
- Microbiology (AREA)
- Artificial Intelligence (AREA)
- Biophysics (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Abstract
Description
Disclosure of the Invention The present disclosure relates to a reaction test strip and a reaction test apparatus using the same.
The term "reaction strip" refers to a kind of test paper used to determine the result of a predetermined chemical reaction. As an example, when a urine test is performed to detect a target antigen in the urine, the test strip may include a reagent comprising an antibody that reacts with the antigen. In addition, the reaction test strip can also easily identify whether the test person has a predetermined target antigen in the urine by expressing the result of the antigen-antibody reaction as a color change.
Brief Description of the Drawings Fig. 1 is a view schematically showing a conventional reaction test strip. Fig. 1 (a), the
In the case of the above-described conventional test strips, the test results can be easily confirmed even by the general public who does not have expert knowledge, by confirming the result of the antigen-antibody reaction through the color change of the reaction site. However, in the inspection industry, in which a large number of test strips are used to check the test results, the above-described method may be subject to various limitations. First, depending on the case, the color indicating the result of the antigen-antibody reaction may vary with time. That is, the antigen-antibody reaction may be contaminated or influenced by the surrounding environment over time and may exhibit undesirable color changes. Secondly, it is therefore necessary to observe the hue of the result of the antigen-antibody reaction within a limited time, which may be difficult to ascertain through manual inspection by the inspector.
The embodiment of the present disclosure provides a reaction inspection strip and an inspection apparatus therefor that can efficiently confirm a predetermined reaction inspection result within a limited time.
Disclosed is a reaction test strip according to one aspect of the present disclosure. The reaction test strip includes a body portion having a predetermined width, height, and length, a plurality of reaction portions arranged along a longitudinal direction of the body portion on one surface of the body portion, And a positional information marker disposed on a surface or inside of the body corresponding to the position of the reaction inspection part and providing position information of the reaction inspection part to the position reading device. The position information markers include at least one of an optical signal pattern, a physical structure pattern, an electric circuit pattern, and an image pattern.
A reaction test apparatus according to another aspect of the present disclosure is disclosed. Wherein the reaction test apparatus comprises a reaction test strip having a reaction test section and a positional information marker disposed at a position corresponding to a position of the reaction test section, a reaction test strip disposed adjacent to the reaction test strip, A position reading device for detecting the position information markers of the reaction test strip when moving in one direction, and a photographing device for photographing the reaction inspection part in synchronization with the timing at which the position reading device detects the position information markers . The position information markers include at least one of an optical signal pattern, a physical structure pattern, an electric circuit pattern, and an image pattern.
According to the present disclosure, the reaction test strip may include a positional information marker that provides positional information of a reaction inspection unit that provides the reaction result with the target material as color information. The image of the reaction inspection part can be easily photographed while moving the reaction inspection strip using the information of the position information markers.
Particularly, in the case of moving the reaction test strip through manual operation, the reaction test strip can be passed through the inspection apparatus with constant velocity or acceleration. In this way, even when the reaction inspection strip moves at a constant speed or acceleration, the image of the reaction inspection part can be acquired quickly by driving the photographing device in synchronization with the position information of the position information markers. The obtained image can be effectively provided to read whether or not the reaction result is within a limited time.
Brief Description of the Drawings Fig. 1 is a view schematically showing a conventional reaction test strip. Fig.
2A schematically shows a reaction test strip according to a first embodiment of the present disclosure;
FIG. 2B is a view schematically showing a method of using the reaction test strip of FIG. 2A. FIG.
3A is a schematic view of a reaction test strip according to a second embodiment of the present disclosure;
FIG. 3B is a view schematically showing a method of using the reaction test strip of FIG. 3A.
Fig. 3c is a schematic view showing another method of using the reaction test strip of Fig. 3a.
4 is a schematic view of a reaction test strip according to a third embodiment of the present disclosure;
Fig. 5 is a view schematically showing a reaction inspection strip according to a fourth embodiment of the present disclosure; Fig.
6A is a view schematically showing a reaction inspection strip according to the sixth embodiment of the present disclosure.
FIG. 6B is a view schematically showing a method of using the reaction test strip of FIG. 6A.
7 is a view schematically showing a reaction inspection strip according to a seventh embodiment of the present disclosure.
8 is a view schematically showing a reaction inspection strip according to an eighth embodiment of the present disclosure.
9A is a view schematically showing a reaction inspection strip according to a ninth embodiment of the present disclosure.
Figs. 9B and 9C are schematic views showing cross sections of portions A and B in the reaction test strip of Fig. 9A. Fig.
FIG. 9D is a view schematically showing a method of using the reaction test strip of FIG. 9A.
10 is a cross-sectional view schematically showing a reaction test strip according to a tenth embodiment of the present disclosure.
11 is a cross-sectional view schematically showing a strip for reaction inspection according to an eleventh embodiment of the present disclosure.
12 is a schematic representation of a reaction test apparatus using a reaction test strip according to one embodiment of the present disclosure;
Figure 13 is a schematic representation of a reaction test apparatus using a reaction test strip according to another embodiment of the present disclosure;
Embodiments of the present disclosure will now be described in more detail with reference to the accompanying drawings. However, the techniques disclosed in this disclosure are not limited to the embodiments described herein but may be embodied in other forms. In the drawings, the width, thickness, and the like of the components are enlarged in order to clearly illustrate the components of each device.
Where an element is referred to herein as being located on another element "above" or "below", it is to be understood that the element is directly on the other element "above" or "below" It means that it can be intervened. In this specification, the terms 'upper' and 'lower' are relative concepts set at the observer's viewpoint. When the viewer's viewpoint is changed, 'upper' may mean 'lower', and 'lower' It may mean.
Like numbers refer to like elements throughout the several views. It is to be understood that the singular forms "a", "an", and "the" include plural referents unless the context clearly dictates otherwise, and the terms "comprise" Or combinations thereof, and does not preclude the presence or addition of one or more other features, integers, steps, operations, elements, components, or combinations thereof.
2A schematically shows a reaction test strip according to a first embodiment of the present disclosure; FIG. 2B is a view schematically showing a method of using the reaction test strip of FIG. 2A. FIG.
2A, the
The
The plurality of
The
As shown in FIG. 2A, the
Referring to FIG. 2B, the
In a more specific embodiment, the
3A is a schematic view of a reaction test strip according to a second embodiment of the present disclosure; FIG. 3B is a view schematically showing a method of using the reaction test strip of FIG. 3A. Fig. 3c is a schematic view showing another method of using the reaction test strip of Fig. 3a.
3A, the
In this embodiment, the
Referring to FIG. 3B, the
The
3C, the
The
4 is a schematic view of a reaction test strip according to a third embodiment of the present disclosure; In a third embodiment, the
4, in the
In one embodiment, the location information indicator 332a may cover the four
When the
Fig. 5 is a view schematically showing a reaction inspection strip according to a fourth embodiment of the present disclosure; Fig. In the fourth embodiment, the
5, the
6A is a view schematically showing a reaction inspection strip according to the sixth embodiment of the present disclosure. FIG. 6B is a view schematically showing a method of using the reaction test strip of FIG. 6A. In this embodiment, the
Referring to FIG. 6A, the
The
The
The
Referring to FIG. 6B, the
After the
7 is a view schematically showing a reaction inspection strip according to a seventh embodiment of the present disclosure. Referring to FIG. 7, the
8 is a view schematically showing a reaction inspection strip according to an eighth embodiment of the present disclosure. Referring to FIG. 8, the
Comparing the second to
9A is a view schematically showing a reaction inspection strip according to a ninth embodiment of the present disclosure. Figs. 9B and 9C are schematic views showing cross sections of portions A and B in the reaction test strip of Fig. 9A. Fig. FIG. 9D is a view schematically showing a method of using the reaction test strip of FIG. 9A.
9A to 9C, the
Referring to FIG. 9D, the
The
The first pad disposed discontinuously on the
10 is a cross-sectional view schematically showing a reaction test strip according to a tenth embodiment of the present disclosure. Referring to FIG. 10, the
The position reading apparatus includes a pair of second pads (not shown) to which predetermined voltages are applied at positions corresponding to the
11 is a cross-sectional view schematically showing a strip for reaction inspection according to an eleventh embodiment of the present disclosure. Referring to Fig. 11, the
In this embodiment, a plurality of first pads corresponding to one reaction inspection part may be disposed on the side wall of the
The position reading apparatus may have the same number of second pads as the number of the first pads corresponding to one reaction inspection unit. Thus, when the first pad and the second pad are in contact, the electrical resistance reduction in the other resistance pattern can be read.
12 is a schematic representation of a reaction test apparatus using a reaction test strip according to one embodiment of the present disclosure; Referring to FIG. 12, the
The
The
In some other embodiments, as the reaction test strip, the reaction test strips described above with reference to Figs. 3A, 4, 5, 6A, 7, 8, 9A, 10, (30, 32, 34, 40, 42, 44, 50, 60, 70) may be applied. Correspondingly, as the position reading apparatus, the
Referring again to FIG. 12, the photographing
The photographing
The
In some embodiments, the
The light polarized in the first direction may be scattered on the surfaces of the
In some embodiments, the polarization states of the light incident on the
Figure 13 is a schematic representation of a reaction test apparatus using a reaction test strip according to another embodiment of the present disclosure; Referring to FIG. 13, the
When the
As described above, the image pattern formed by the interface between the
As described above, the inspection method using the reaction inspection apparatus can be diluted through the following steps. A reaction test strip and a positional information marker disposed at a position corresponding to the position of the reaction test strip. Next, a position reading device is disposed adjacent to the reaction inspection strip, and the reaction inspection strip is moved at a constant speed or acceleration in one direction, and the reaction inspection strip is allowed to move through the position reading device. Next, in synchronism with the timing at which the position information marker is detected by the position reading device, the reaction inspection part is photographed using the photographing device.
While the present invention has been particularly shown and described with reference to exemplary embodiments thereof, it will be understood by those of ordinary skill in the art that various changes in form and details may be made therein without departing from the spirit and scope of the invention as defined by the appended claims. It can be understood that
10 20 30 32 34 40 42 44 50 60 70 80: Strip for reaction test
1200 1300: reaction test equipment,
105: body portion, 110 120 130 140 150: plural reaction sites,
160: urine, 170: container,
210: body portion, 220a 220b ... 220l: reaction test section,
232a 232b ... 232l, 234a 234b ... 234l: Location information markers,
240: Strip transducer, 250: Position reader,
252a 252b: sensor,
260: photographing device, 262: light source, 264: photodetector,
330a 330b ... 330l: location information marker,
350 360: Position reading device, 362: Light source, 364: Photodetector,
41 42 43 44: first to fourth segments,
41t, 42t, 43t, 44t: first to fourth buttons,
410 412 414 416: first to fourth bodies,
420a 420b 420c ... 420l: reaction test section,
440 540: Strip converters,
442, 444, 446, 448: first to fourth rails,
550: position reading device,
51 52 53 54: first to fourth segments,
530a 530b ... 530l: first pad,
550a: Fixing portion, 550b: Sensing portion,
631
730h1 730h2 ... 730h6, 730g1 730g2 ... 730g6: first pad,
Claims (16)
A plurality of reaction inspectors arranged along the length direction of the body part on one side of the body part and providing the result of the reaction with the target material as color information; And
And a position information marker disposed on a surface of or inside the body corresponding to the position of the reaction inspecting part and providing position information of the reaction inspecting part to the position reading device,
Wherein the position information markers comprise at least one of an optical signal pattern, a physical structure pattern, an electrical circuit pattern, and an image pattern
Strip for reaction test.
The optical signal pattern
And a bar code disposed on a surface of the body corresponding to the positions of the plurality of reaction inspection units
Strip for reaction test.
The physical structure pattern
And a protruding structure or a concave structure disposed on a side portion of the body portion corresponding to the positions of the plurality of reaction inspection portions
Strip for reaction test.
The physical structure pattern
And a stepped pattern having the different width along the longitudinal direction of the body part
Strip for reaction test.
The electrical circuit pattern
And a resistance pattern disposed under the plurality of reaction inspection units,
Wherein the resistance pattern changes depending on the contact with the position reading apparatus
Strip for reaction test.
The image pattern
And a pattern formed by the interface between the body portion and the reaction inspection portion on one side of the body portion,
And is read by edge detection of the position reading apparatus
Strip for reaction test.
A position reading device disposed adjacent to the reaction inspection strip and detecting the position information markers of the reaction inspection strip when the reaction inspection strip moves at a constant speed or acceleration in one direction; And
And a photographing device which photographs the reaction inspection part in synchronization with the timing at which the position reading device detects the position information markers,
Wherein the position information markers comprise at least one of an optical signal pattern, a physical structure pattern, an electrical circuit pattern, and an image pattern
Reaction testing device.
The reaction test strip
A body portion having a predetermined width, height and length,
The reaction inspection unit may include a plurality of reaction inspection units arranged along a longitudinal direction of the body part on one side of the body part and providing a reaction result with the target material as color information,
Wherein the position information marker is disposed on a surface or inside of the body part, and provides position information of the reaction inspection part to the position reading device
Reaction testing device.
Wherein the position information marker includes a barcode as an optical signal pattern on a side portion of the body portion,
When the reaction inspection strip moves through the position reading device, the position reading device reads the bar code and transmits a photographing signal to the photographing device
Reaction testing device.
Wherein the position information marker includes a protruding structure or a concave structure disposed on a side surface of the body portion,
When the reaction inspection strip moves through the position reading device, the position reading device reads an image of the protruding structure or the concave structure and transmits a photographing signal to the photographing device
Reaction testing device.
Wherein the positional information marker has the step portion of the different width along the longitudinal direction of the body portion,
When the step portion contacts the reaction inspection strip moving through the position reading device, the position reading device sequentially transmits the photographing control signal to the photographing device
Reaction testing device.
Wherein the position information marker includes a resistance pattern disposed under the plurality of reaction inspection units,
The position reading apparatus transmits the photographing control signal to the photographing apparatus when the electrical resistance changes due to the contact of the resistance pattern with the reaction inspection strip moving through the position reading apparatus
Reaction testing device.
Wherein the position information marker includes an image pattern formed by the body part and the interface between the reaction part and the reaction part on one side of the body part,
When the reaction test strip moves through the position reading device, the position reading device reads the image pattern and transmits a photographing signal to the photographing device
Reaction testing device.
The photographing apparatus
A light source for providing visible light or ultraviolet light; And
And a photodetector disposed adjacent the light source and having a color sensor
Reaction testing device.
Wherein the light source comprises a first polarizing filter polarized in a first direction,
Wherein the photodetector comprises a second polarizing filter polarized in a direction perpendicular to the first direction
Reaction testing device.
Further comprising a beam splitter disposed on an optical path between the light source and the reaction inspection strip and an optical path between the reaction inspection strip and the photodetector,
The light polarized in the first direction from the light source is incident on the reaction inspection unit and light polarized in the direction perpendicular to the first direction among the light scattered from the reaction inspection unit is detected by the photodetector
Reaction testing device.
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KR1020150036679A KR20160111693A (en) | 2015-03-17 | 2015-03-17 | strip for inspecting reaction, inspection apparatus of strip |
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KR1020150036679A KR20160111693A (en) | 2015-03-17 | 2015-03-17 | strip for inspecting reaction, inspection apparatus of strip |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108663321A (en) * | 2018-04-02 | 2018-10-16 | 迈克医疗电子有限公司 | A kind of measuring head, the urine dry chemistry Analyzer and its detection method |
WO2019107666A1 (en) * | 2017-11-29 | 2019-06-06 | 한양대학교 산학협력단 | Urine test strip comprising timer, and method for detecting and analyzing urine test strip |
-
2015
- 2015-03-17 KR KR1020150036679A patent/KR20160111693A/en unknown
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2019107666A1 (en) * | 2017-11-29 | 2019-06-06 | 한양대학교 산학협력단 | Urine test strip comprising timer, and method for detecting and analyzing urine test strip |
KR20190062775A (en) * | 2017-11-29 | 2019-06-07 | 한양대학교 산학협력단 | Urine test strip including timer, method for detecting and analyzing urine test strip |
US11333658B2 (en) | 2017-11-29 | 2022-05-17 | Industry-University Cooperation Foundation Hanyang University | Urine test strip comprising timer, and method for detecting and analyzing urine test strip |
CN108663321A (en) * | 2018-04-02 | 2018-10-16 | 迈克医疗电子有限公司 | A kind of measuring head, the urine dry chemistry Analyzer and its detection method |
CN108663321B (en) * | 2018-04-02 | 2024-04-05 | 迈克医疗电子有限公司 | Test head, urine dry chemical analyzer and detection method thereof |
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