KR20140124172A - Cosmetic Compositions for Skin improvement - Google Patents
Cosmetic Compositions for Skin improvement Download PDFInfo
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- KR20140124172A KR20140124172A KR20130041566A KR20130041566A KR20140124172A KR 20140124172 A KR20140124172 A KR 20140124172A KR 20130041566 A KR20130041566 A KR 20130041566A KR 20130041566 A KR20130041566 A KR 20130041566A KR 20140124172 A KR20140124172 A KR 20140124172A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/77—Sapindaceae (Soapberry family), e.g. lychee or soapberry
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/78—Saururaceae (Lizard's-tail family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
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Abstract
Description
The present invention relates to a skin-improving cosmetic composition, and more particularly, to a skin-improving cosmetic composition having an excellent effect on atopy.
In general, atopy refers to an allergic symptom that appears in the skin, respiratory mucosa, stabilization membrane, and the immune membrane in an individual with atopic asthma, which means "abnormal response" or "strange" in Greek.
Atopic dermatitis, a typical skin disease that occurs in people with atopic allergies, causes inflammation and itching in the skin, which causes light, dry, sensitive skin, and thus provides a lot of discomfort to people suffering from atopic dermatitis.
Atopic dermatitis can cause many painful infants and young children. It can scratch the skin because of itching day and night, putting on sleep, changing the skin in a terrible manner, and at the same time, There is a problem that can lead to maladjustment.
Recently, there have been many cases of atopic dermatitis due to diversification of living environment due to diversification of social life such as environmental factors and mental stress.
Such atopic dermatitis deterioration factors include dry skin, changes in ambient temperature and humidity, severe exercise and excessive sweating, skin irritation caused by wool and fibers, food, drug, house dust, animal hair, irritant chemicals, The cause and the factors causing atopic dermatitis are also diversified.
In order to solve such a problem, Korean Patent Publication No. 2010-0058143 discloses a composition for treating skin diseases which does not have side effects by fermenting natural minerals as a microorganism, and a method for producing the composition. However, in the prevention and treatment of atopic skin, It may cause problems such as causing an irritation reaction, and there is a problem that there is a limitation in its use, so that it is difficult to use it for general purpose.
In addition, the registered patent No. 0436384 discloses a skin-improving cosmetic composition which is prepared by mixing 63 kinds of natural plant extracts and is effective for removing skin or keratin. However, there is a problem in that there is a risk of side effects due to an excessive amount of ingredient composition there was.
Accordingly, it is an object of the present invention to provide a skin-improving cosmetic composition capable of helping skin diseases to solve such a problem.
Another object of the present invention is to provide a cosmetic composition for improving skin which is effective for skin diseases, which can contribute to the promotion of energy metabolism by discharging toxicity of the body.
In order to attain the above object, the skin-improving cosmetic composition of the present invention is characterized in that it comprises a carnauba, a tangerine, and a horseradish.
The skin-improving cosmetic composition may further contain 30 to 100 parts by weight of a Peppermint Extract, 10 to 40 parts by weight of a Pepper Extract, 10 to 40 parts by weight of a Pepper Extract, 1 part by weight of an apple extract, 1 part by weight of a carrot extract, 1 part by weight of cucumber extract, 1 part by weight of citron extract, and 0.5 part by weight of Angelica gigas extract.
The skin-improving cosmetic composition of the present invention is characterized in that it contains 65 parts by weight of a carnauba wax extract, 25 parts by weight of a tangerine extract, and 25 parts by weight of an extract of Horseradish.
In addition, the skin-improving cosmetic composition is characterized by being effective for anti-inflammatory, atopic dermatitis, eczema, athlete's foot, skin itching, rhinitis, hair loss, and dandruff.
Accordingly, the present invention has no side effects on skin without using artificial chemicals, and has excellent antimicrobial properties, and is effective for improving various skin such as atopic skin diseases and athlete's foot, and has an effect of skin improvement.
In addition, since it has an antibacterial and anti-inflammatory action, it has an excellent effect in the treatment of various skin diseases such as eczema, skin itching, swelling, hair growth, etc. in addition to the atopic skin disease.
In order to attain the above object, the composition of the present invention is characterized in that it comprises a caraway, a tangerine, and a horseradish.
The skin-improving cosmetic composition may further contain 30 to 100 parts by weight of a Peppermint Extract, 10 to 40 parts by weight of a Pepper Extract, 10 to 40 parts by weight of a Pepper Extract, 1 part by weight of an apple extract, 1 part by weight of a carrot extract, 1 part by weight of cucumber extract, 1 part by weight of citron extract, and 0.5 part by weight of Angelica gigas extract.
The skin-improving cosmetic composition of the present invention is characterized in that it contains 65 parts by weight of a carnauba wax extract, 25 parts by weight of a tangerine extract, and 25 parts by weight of an extract of Horseradish.
In addition, the skin-improving cosmetic composition is characterized by being effective for anti-inflammatory, atopic dermatitis, eczema, athlete's foot, skin itching, rhinitis, hair loss, and dandruff.
Hereinafter, embodiments of the present invention will be described in detail.
First, the general properties and pharmacological actions of natural products used in the skin-improving cosmetic composition of the present invention will be described.
Purslane is a medicinal herb that helps to acne and freckles caused by skin, and is useful for skin care. It plays a role of eliminating viruses such as dysentery, and is effective for intestinal health. It prevents the uterine bleeding in women and suppresses mental stress Is also known as a helpful herb.
Tangerine is effective against urticaria and itching, has a good effect on atopy, and is known as a fruit that is good for treating constipation.
It is a detoxifying herb that cleanse all kinds of toxins in the body, cleanses the intestines, has effects on constipation, smoothes the metabolism of blood, and also works on hypertension and atopy.
In addition, it has excellent antifungal activity against katharrh or Influenza bacillus, Streptococcus pneumoniae, Staphylococcus aureus and the like, and has excellent antiviral action against influenza A type, Action, prevention of hypertension and enhancement of capillary blood vessels.
Hereinafter, apples, carrots, mandarins, cucumbers, citron fruits, and angelica that are incorporated into the composition of the present invention will be described.
Apples contain 85-90% moisture, 1% pectin, 1% fiber and 0.5% malic acid. They also contain small amounts of ash protein. Vitamin A contains 60g of vitamin A, 0.01mg of vitamin B1, 8 mg or less.
Pectin, a vegetable fiber contained in apples, acts to prevent colon cancer, to stimulate bowel movements, to regulate blood sugar and to reduce cholesterol, and to improve the hormone function of apples. Stabilizes your mind, helps you sleep and helps with skin beauty
Because carrots are rich in vitamin A, they increase resistance of the mucous membranes, help prevent eye fatigue, asthma, gastric ulcers, and also help maintain blood circulation and heal poor circulation and alumni. In addition, it stimulates the secretion of corticosteroid hormone, so that autonomic nervous breakdown caused by stress, skin roughness, pathological hair loss, etc. are healed and hair is shiny.
Beta cryptosanthin, a component of mandarin oranges, has a very strong antioxidant and anti-inflammatory effect, and eating four or more mandarins a day lowers the incidence of diabetes, hypertension and heart disease.
Women who eat a lot of mandarin orange have the effect of reducing the risk of cervical cancer and preventing arthritis, which increases bone density. In addition, citric acid rich in citrus improves appetite, refreshing flavor and refreshing the head, reducing fat accumulation by 48%, effective diet and improve blood flow.
Also, in the skin of mandarin, vitamin C is contained four times more than flesh and there are anti-cancer components. The fresh directional component of the tangerine peel stimulates the skin and stimulates blood circulation of the capillary blood vessels, so that stress on the skin surface is relaxed and the action of the viscera becomes active. Tangerine peel is used as a medicine to help the blood circulation disorder, stress, etc. are treated.
Cucumber is a strong alkaline food, neutralizes the acidified body, diuretic action helps to remove the swelling, heat and detoxification effect is excellent, it is considered as a sign of burns, itching and calm, cucumber Vitamin C metabolism Smooth, prevent colds, relieve fatigue and thirst.
Yuzu is used as a medicinal product to lower the iron in the oriental medicine. Ingredients are similar to mandarin orange, but vitamin C is much higher than mandarin orange. It also contains citric acid to relieve fatigue and to eliminate the stomach after overdose. Eliminates the bad aura of the stomach and cures indigestion. Citron tea made from citron as tea material warms the body and promotes digestion, it exerts excellent efficacy when it gets cold with a cold, chills and fever.
Hesperidin, which is found in the inner and outer shells of citrus fruits, plays a role in preventing circulatory diseases and strengthens the capillary resistance so as to prevent hemorrhage and subarachnoid hemorrhage caused by blood vessel rupture.
Angelica mainly has a lot of effects on women, it relieves the pain and makes the blood vigorous, so when you are in the abdomen after the birth, the blood circulation will be smooth and the blood will be released. If you take it steadily, It neutralizes toxins in the body and stimulates intestinal motility to improve digestion and constipation. In addition, the powerful antioxidant activity of Angelica gigas and the blood circulation effect on the scalp prevent hair loss and white hair.
In addition, ingredients such as licorice can be incorporated into the composition to make it a preservative to have a long shelf life.
The use of the cosmetic composition for skin improvement of the present invention is sprayed or applied several times to a lesion such as an atopic skin disease or athlete's foot.
If you keep applying it in this way, the symptoms such as itching will begin to disappear and the wound area will gradually regenerate into normal skin.
Therefore, unlike the conventional skin remedy, even if it is repeatedly applied to the skin, not only side effects such as skin irritation but also athlete's foot have been shown to be effective.
Hereinafter, the present invention will be described in detail with reference to examples. It is to be understood that the following examples are for the purpose of illustrating the present invention more specifically and that the scope of the present invention is not limited to these examples in accordance with the gist of the present invention.
Example 1: Preparation of skin-improving cosmetic composition according to the present invention
The mixture was agitated for about 1 hour, and then agitated for about 3 hours.
Thereafter, 575 ml of ethanol is added and aged at room temperature for about 7 days. The extract is filtered with a filter having a size of 0.1 to 2 micrometers, and then concentrated under reduced pressure to prepare a concentrate of carrot, persimmon and persimmon.
1 g of apple, 1 g of carrot, 1 g of cucumber, 1 g of citron, 1 g of citron and 0.5 g of Angelica grisea were mixed and mixed. After stirring for about 3 hours, the mixture was aged for 3 days at room temperature, After filtration with a filter of the meter size, it is concentrated under reduced pressure to prepare apple, carrot, mandarin orange, cucumber, citron and Angelica gigantea.
The concentrate mixture was stirred and aged for 10 days in a low-temperature refrigerator of about 3 to 5 degrees to prepare a cosmetic composition of the present invention.
[Experimental Example 1] Inhibitory effect on PGE 2 production
PGE 2 production inhibitory effect test was carried out in order to confirm the anti-inflammatory effect on the skin troubles with the extracts of Pseudomonas spp. (Jeffrey, KH, Anglea, SW, Zoe, S. and Rhia CM, Intracellular Measurement of Prostaglandin E2: Effect of anti-inflammatory drugs on cyclooxygenase activity and prostanoid expression, Analytical Biochemistry, 1999, 271, 18-28)
RAW 264.7 cells, macrophage lineage, were subcultured several times, and then 1 × 10 5 cells were placed in a 24-well plate and cultured in a 5% CO 2 thermostat for 24 hours.
Subsequently, the medium was removed, and a new medium containing 50 μl of a sample of carrot, tadalafia, and horseradish prepared with a 10-fold concentration (1 mg / ml) and 450 μl of LPS (1 μg / Lt; / RTI > After 24 hours, the supernatant was obtained by centrifuging the culture medium (12,000 rpm, 3 min) to measure PGE 2 .
PGE 2 was determined by enzyme-linked immunosorbent assay (ELISA). The inhibitory effect of PGE 2 on the extracts of Chinese herbal medicines was determined and the results are shown in Table 1 below.
Therefore, as shown in Table 1, the major constituents of the composition of the present invention such as carrageenan, tangerine, and horseradish have excellent antiproliferative efficacy because they exhibit an extremely potent inhibitory effect on prostaglandin (PGE 2 ).
[Effect 1] Effect of the cosmetic composition for skin improvement according to the present invention on atopic dermatitis
700 patients with atopic dermatitis over 18 years of age with the above cosmetic composition were treated with the composition according to the present invention for 1 month, and the progress was examined. 80 people were cured, 200 people had a remarkable effect, 400 people had a constant effect, and the rest were not changed.
Therefore, the composition according to the present invention has proven effective for atopic dermatitis.
[Effect 2] Effect of the skin-improving cosmetic composition of the present invention on eczema
100 patients with an eczema of 18 years or older were treated with the cosmetic composition according to the present invention for 10 days, 18 patients were cured, 20 had a remarkable effect, 63 had a certain effect, and the remaining 9 had a change There was no.
Thus, the composition according to the present invention has proven effective in eczema.
[Effect 3] Effect of the skin-improving cosmetic composition of the present invention on athlete's foot
100 patients with athlete's foot over 18 years of age were treated with the composition for treating skin diseases according to the present invention for about 20 days to observe the prognosis. Seven patients were cured, 20 patients were remarkably effective, 70 patients were improved, There was no change.
Thus, the compositions of the present invention have been shown to be effective for athlete's foot.
[Effect 4] Effect of the skin-improving cosmetic composition of the present invention on skin itching
220 patients with skin itching over 18 years of age were treated with the therapeutic cosmetic composition according to the present invention for 5 days, and the prognosis was examined. 10 people were cured, 16 people had a remarkable effect, 190 people improved, and 4 others remained unchanged.
Thus, the compositions of the present invention have been shown to be effective for skin itching.
[Effect 5] Effect of the skin-improving cosmetic composition of the present invention on allergic rhinitis
Fifty patients with allergic rhinitis over 18 years of age were treated with the composition for 5 days. Five patients were cured, 14 had a remarkable remarkable effect, 30 had improvement, and the other one did not change.
Therefore, the skin improving cosmetic composition of the present invention has been proved to be effective for allergic rhinitis.
[Effect 6] Effect of the skin-improving cosmetic composition of the present invention on hair loss
69 patients with hair loss symptoms over 18 years of age were treated with the composition for treating skin diseases of the present invention for 50 days to observe the prognosis. Four people were cured, 15 had a remarkable effect, 45 showed improvement, and 5 had no change.
Thus, the skin-improving cosmetic composition of the present invention has proved to be effective for hair loss symptoms
[Effect 7] Effect of the skin-improving cosmetic composition of the present invention on dandruff
70 patients with dandruff of 18 years or older were treated with the composition for treating skin diseases of the present invention for 10 days to observe the prognosis. Seventeen patients were cured, 50 had significant effects, and three had no change.
Thus, the skin-improving cosmetic composition of the present invention has proven effective for dandruff.
As described above, the skin-improving cosmetic composition according to the present invention has an excellent merit for an increasing number of patients with atopic dermatitis due to diversification of living environment due to diversification of social life such as environmental factors and mental stress will be.
As a result of the experiment, it was found that the effect of the present invention was similar to that of the above Example, in the range of 30-100 parts by weight, 40-40 parts by weight of Tangerine extract, and 10-40 parts by weight of Houttuynia cordata extract.
Claims (4)
A composition for skin-improving cosmetic composition, comprising a composition comprising:
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20220058361A (en) * | 2020-10-30 | 2022-05-09 | (주)리윤바이오 | Cosmetic composition for moisturizing and improvement of skin itching comprising the extract of natural products |
KR20220112636A (en) * | 2021-02-04 | 2022-08-11 | (주)리윤바이오 | Cosmetic composition helping in improving water content in corneous lower layer comprising the extract of natural products |
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2013
- 2013-04-16 KR KR20130041566A patent/KR20140124172A/en not_active Application Discontinuation
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20220058361A (en) * | 2020-10-30 | 2022-05-09 | (주)리윤바이오 | Cosmetic composition for moisturizing and improvement of skin itching comprising the extract of natural products |
KR20220112636A (en) * | 2021-02-04 | 2022-08-11 | (주)리윤바이오 | Cosmetic composition helping in improving water content in corneous lower layer comprising the extract of natural products |
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