KR20120041658A - Cosmetics - Google Patents
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- KR20120041658A KR20120041658A KR1020110100960A KR20110100960A KR20120041658A KR 20120041658 A KR20120041658 A KR 20120041658A KR 1020110100960 A KR1020110100960 A KR 1020110100960A KR 20110100960 A KR20110100960 A KR 20110100960A KR 20120041658 A KR20120041658 A KR 20120041658A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/86—Polyethers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/362—Polycarboxylic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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Abstract
Description
본 발명은 화장료의 기술분야에 관한 것이다.The present invention relates to the technical field of cosmetics.
본 출원인은, 폴리메타크릴산 메톡시 폴리에틸렌글리콜이 갖는 보습성을 발견하고, 화장료의 특허를 출원하였다(특허문헌 1: 일본국 특허공개 제2003-171257호 공보).The present applicant discovered the moisture retention which polymethacrylic-acid methoxy polyethyleneglycol has, and applied for the patent of cosmetics (patent document 1: Unexamined-Japanese-Patent No. 2003-171257).
그러나, 더욱 보습성이 높은 화장료를 제공하는 기술이 요구되고 있다.However, there is a need for a technique for providing a more moisturizing cosmetic.
본 발명은, 폴리메타크릴산 메톡시 폴리에틸렌글리콜을 함유하는 화장료의 보습성을 높이는 것을 과제로 한다.This invention makes it a subject to improve the moisture retention of the cosmetics containing polymethacrylic-methoxy methoxy polyethyleneglycol.
본 발명의 주된 구성은, 다음과 같다.The main structure of this invention is as follows.
(1) 폴리메타크릴산 메톡시 폴리에틸렌글리콜(A)과 폴리옥시에틸렌 메틸글루코시드(B)를 함유하는 화장료.(1) Cosmetics containing polymethacrylic acid methoxy polyethyleneglycol (A) and polyoxyethylene methyl glucoside (B).
(2) 폴리메타크릴산 메톡시 폴리에틸렌글리콜(A)과 폴리옥시에틸렌 메틸글루코시드(B)를 함유하는 보습 화장료.(2) A moisturizing cosmetic containing polymethacrylic acid methoxy polyethylene glycol (A) and polyoxyethylene methyl glucoside (B).
(3) 폴리메타크릴산 메톡시 폴리에틸렌글리콜(A)은, 폴리스티렌 환산 수 평균 분자량 1000~100000인 것을 특징으로 하는 (1) 또는 (2)에 기재된 화장료.(3) Polymethacrylic acid methoxy polyethyleneglycol (A) is polystyrene conversion number average molecular weight 1000-100000, The cosmetics as described in (1) or (2) characterized by the above-mentioned.
(4) 폴리옥시에틸렌 메틸글루코시드(B)는, 메틸글루코오스의 폴리에틸렌글리콜 에테르이고, 다음의 화학식으로 나타내는 것을 특징으로 하는 (1)~(3) 중 어느 하나에 기재된 화장료.(4) Polyoxyethylene methyl glucoside (B) is a polyethyleneglycol ether of methyl glucose, and is represented by the following general formula, The cosmetic according to any one of (1) to (3).
피부면에 문질러 바름으로써, 각질층의 수분량이 높아져, 피부 표면으로부터의 수분 증산량을 억제하여, 보습성이 우수한 화장료를 제공할 수 있다. 폴리메타크릴산 메톡시 폴리에틸렌글리콜과 폴리옥시에틸렌 메틸글루코시드를 조합시킴으로써, 보습성을 향상시킬 수 있는 것이 확인되어, 피부 거칠어짐 개선, 피부 거칠어짐 방지에 효과가 있다.By rubbing on the skin surface, the moisture content of the stratum corneum increases, the amount of water evaporation from the skin surface can be suppressed, and a cosmetic excellent in moisture retention can be provided. By combining polymethacrylic acid methoxy polyethyleneglycol and polyoxyethylene methylglucoside, it is confirmed that moisture retention can be improved, and it is effective in improving skin roughness and preventing skin roughness.
도 1은 각질층 수분량의 시험결과를 나타내는 그래프이다.
도 2는 피부로부터의 수분 증산량 시험결과를 나타내는 그래프이다.1 is a graph showing the test results of the stratum corneum moisture content.
Fig. 2 is a graph showing the test results of water transpiration from the skin.
본 발명에 적용되는 폴리메타크릴산 메톡시 폴리에틸렌글리콜은, 메타크릴산 메톡시 폴리에틸렌글리콜을 단독 중합시켜 얻어지는 것이다.Polymethacrylic acid methoxy polyethyleneglycol applied to this invention is obtained by homopolymerizing methacrylic acid methoxy polyethyleneglycol.
메타크릴산 메톡시 폴리에틸렌글리콜은, 예를 들면, 폴리에틸렌글리콜 메틸 에테르와 메타크릴산 클로라이드를 반응시켜서 얻을 수 있다. 또한, 일부는 시약으로서 시판되고 있는 것도 있다. 예를 들면, 신나카무라 가가꾸 고교 가부시키가이샤로부터 시판된 NK에스테르M-230G(n≒23), NK에스테르M-90G(n≒9), 니치유 가부시키가이샤로부터 시판된 블렘머PME-1000(n≒23), 블렘머PME-400(n≒9), 블렘머PME-200(n≒4)을 모노머로서 사용할 수 있다. 다음으로, 중합체의 제조방법에 대해서 통상의 방법에 따르면 되고, 모노머를 용매 중에서 중합개시제의 존재하, 반응시켜 얻어진다.Methacrylic acid methoxy polyethyleneglycol can be obtained, for example by making polyethyleneglycol methyl ether and methacrylic acid chloride react. In addition, some of them are commercially available as reagents. For example, NK ester M-230G (n ≒ 23), NK ester M-90G (n ≒ 9) sold by Shin-Nakamura Kagaku Kogyo Co., Ltd., and Blemmer PME-1000 sold by Nichiyu Corporation (n # 23), Blemmer PME-400 (n # 9), and Blemmer PME-200 (n # 4) can be used as the monomer. Next, the method for producing a polymer may be in accordance with a conventional method, and is obtained by reacting a monomer in the presence of a polymerization initiator in a solvent.
이하에, 본 발명의 폴리메타크릴산 메톡시 폴리에틸렌글리콜의 합성예를 나타낸다.Below, the synthesis example of the polymethacrylic-methoxy methoxy polyethyleneglycol of this invention is shown.
합성예 1 폴리메타크릴산 메톡시 폴리에틸렌글리콜(폴리옥시에틸렌 사슬의 평균 중합도가 4.5)Synthesis Example 1 Polymethacrylate methoxy polyethylene glycol (average degree of polymerization of polyoxyethylene chain 4.5)
100 ㎖ 둥근 바닥 플라스크에 중합개시제 AIBN을 0.0306 g 계량하고, 플라스크 내를 아르곤 가스로 3회 치환한 후, 30 ㎖의 증류 벤젠을 첨가하여 AIBN이 용해될 때까지 실온하에서 교반하였다. 이것에 폴리에틸렌글리콜 메틸 에테르메타크릴레이트(PEG의 평균 중합도는 4.5)를 5 ㎖ 첨가하고, 60℃에서 48시간, 계속해서 70℃에서 24시간 가열하여, 중합을 행하였다. 그 후, 중합을 정지하고 목적물을 회수하였다.0.0306 g of the polymerization initiator AIBN was weighed into a 100 ml round bottom flask, and the flask was replaced with argon gas three times, followed by addition of 30 ml of distilled benzene, followed by stirring at room temperature until the AIBN was dissolved. 5 ml of polyethyleneglycol methyl ether methacrylate (the average degree of polymerization of PEG is 4.5) was added to this, and it heated at 60 degreeC for 48 hours, and then heated at 70 degreeC for 24 hours, and superposed | polymerized. Thereafter, the polymerization was stopped to recover the target product.
합성예 2 폴리메타크릴산 메톡시 폴리에틸렌글리콜(폴리옥시에틸렌 사슬의 평균 중합도가 9)Synthesis Example 2 Polymethacrylate methoxy polyethylene glycol (average degree of polymerization of polyoxyethylene chain 9)
100 ㎖ 둥근 바닥 플라스크에 중합개시제 AIBN을 0.0403 g 계량하고, 플라스크 내를 아르곤 가스로 3회 치환한 후, 30 ㎖의 증류 벤젠을 첨가하여 AIBN이 용해될 때까지 실온하에서 교반하였다. 이것에 폴리에틸렌글리콜 메틸 에테르메타크릴레이트(PEG의 평균 중합도는 9)를 5 ㎖ 첨가하고, 60℃에서 48시간, 계속해서 70℃에서 24시간 가열하여, 중합을 행하였다. 그 후, 중합을 정지하고 목적물을 회수하였다.0.0403 g of the polymerization initiator AIBN was weighed into a 100 ml round bottom flask, and the flask was replaced with argon gas three times, followed by addition of 30 ml of distilled benzene, followed by stirring at room temperature until the AIBN was dissolved. 5 ml of polyethyleneglycol methyl ether methacrylate (the average degree of polymerization of PEG is 9) was added to this, and it heated for 48 hours at 60 degreeC, and then heated at 70 degreeC for 24 hours, and superposed | polymerized. Thereafter, the polymerization was stopped to recover the target product.
합성예 3 폴리메타크릴산 메톡시 폴리에틸렌글리콜(폴리옥시에틸렌 사슬의 평균 중합도가 22.7)Synthesis Example 3 Polymethacrylate methoxy polyethylene glycol (average degree of polymerization of polyoxyethylene chain 22.7)
100 ㎖ 둥근 바닥 플라스크에 중합개시제 AIBN을 0.00753 g 계량하고, 플라스크 내를 아르곤 가스로 3회 치환한 후, 30 ㎖의 증류 벤젠을 첨가하여 AIBN이 용해될 때까지 실온하에서 교반하였다. 이것에 폴리에틸렌글리콜 메틸 에테르메타크릴레이트(PEG의 평균 중합도는 22.7)을 5 ㎖ 첨가하고, 60℃에서 48시간, 계속해서 70℃에서 24시간 가열하여, 중합을 행하였다. 그 후, 중합을 정지하고 목적물을 회수하였다.0.00753 g of the polymerization initiator AIBN was weighed into a 100 ml round bottom flask, and the flask was replaced with argon gas three times, followed by addition of 30 ml of distilled benzene, followed by stirring at room temperature until the AIBN was dissolved. 5 ml of polyethyleneglycol methyl ether methacrylate (the average degree of polymerization of PEG is 22.7) was added to this, and it heated for 48 hours at 60 degreeC, and then heated at 70 degreeC for 24 hours, and superposed | polymerized. Thereafter, the polymerization was stopped to recover the target product.
얻어진 폴리메타크릴산 메톡시 폴리에틸렌글리콜의 분자량을 GPC를 사용하여 측정하였다. 그 결과, 합성예 1의 분자량은 폴리스티렌 환산으로 수 평균 분자량 Mn=13800, 질량 평균 분자량 Mw=40400이었다. 합성예 2의 분자량은 폴리스티렌 환산으로 수 평균 분자량 Mn=15363, 질량 평균 분자량 Mw=35680이었다. 합성예 3의 분자량은 폴리스티렌 환산으로 수 평균 분자량 Mn=8300, 질량 평균 분자량 Mw=10000이었다.The molecular weight of the obtained polymethacrylate methoxy polyethyleneglycol was measured using GPC. As a result, the molecular weight of Synthesis Example 1 was number average molecular weight Mn = 13800, and mass average molecular weight Mw = 40400 in polystyrene conversion. The molecular weight of the synthesis example 2 was number average molecular weight Mn = 15363, and mass mean molecular weight Mw = 35680 in polystyrene conversion. The molecular weight of the synthesis example 3 was number average molecular weight Mn = 8300, and mass mean molecular weight Mw = 10000 in polystyrene conversion.
상기와 같이 하여 얻어지는 본 발명의 폴리메타크릴산 메톡시 폴리에틸렌글리콜의 분자량은, 그 사용 목적에 따라서 각종 조정할 수 있지만, 통상은 폴리스티렌 환산으로 1000 이상, 100000 이하이고, 바람직하게는 2500 이상, 100000 이하이다. 본 발명의 화장료의 경우는, 상기 중합체가 화장료 전체에 대해서, 통상 0.05~20 질량%의 범위에서 함유된다.Although the molecular weight of the polymethacrylic-methoxy methoxy polyethyleneglycol of this invention obtained as mentioned above can be variously adjusted according to the use purpose, Usually, it is 1000 or more and 100000 or less in polystyrene conversion, Preferably it is 2500 or more and 100000 or less to be. In the case of the cosmetics of this invention, the said polymer is contained in 0.05-20 mass% with respect to the whole cosmetics normally.
0.05 질량%에 못미치면 보습성이 불충분한 경우가 있고, 20 질량%를 초과하면 끈적거리므로 바람직하지 않다.If it is less than 0.05 mass%, moisture retention may be inadequate, and when it exceeds 20 mass%, it is unpreferable since it is sticky.
본 발명에 사용하는 폴리옥시에틸렌 메틸글루코시드는, 메틸글루코오스의 폴리에틸렌글리콜에테르이고, 다음의 화학식으로 나타내어진다.Polyoxyethylene methyl glucoside used for this invention is polyethyleneglycol ether of methyl glucose, and is represented by the following chemical formula.
여기에서 옥시에틸렌기의 중합도 n은 5~30이 바람직하다.As for polymerization degree n of an oxyethylene group, 5-30 are preferable here.
폴리옥시에틸렌 메틸글루코시드는 시판품을 사용할 수 있다. 옥시에틸렌기의 평균 중합도 n이 10이고, 화장품의 성분 표시 명칭이 메틸글루세스-10인 것으로서, 일본유지 제조:맥비오브라이드MG-10E, 노베온 제조:GLUCAME E-10을 사용할 수 있다.A commercial item can be used for polyoxyethylene methyl glucoside. As the average degree of polymerization n of the oxyethylene group is 10 and the name of the component label of the cosmetic is methylgluses-10, Japanese oil and fat manufacture: McBioBride MG-10E and Noveon: GLUCAME E-10 can be used.
옥시에틸렌기의 평균 중합도 n이 20이고, 화장품의 성분 표시 명칭이 메틸글루세스-20인 것으로서, 일본유지 제조:맥비오브라이드MG-20E, 노베온 제조:GLUCAME E-20을 사용할 수 있다.As the average degree of polymerization n of the oxyethylene group is 20, and the ingredient labeling name of the cosmetic is methylgluses-20, Japanese fats and oils manufacture: MacBioBride MG-20E and Noveon: GLUCAME E-20 can be used.
폴리옥시에틸렌 메틸글루코시드의 배합량은, 전체 화장료에 대해서 0.05 질량% 이상 10.0 질량% 이하가 바람직하다. 0.05 질량%에 못미치면 보습성이 불충분한 경우가 있고, 10.0 질량%를 초과하면 끈적거리므로 바람직하지 않다.As for the compounding quantity of polyoxyethylene methyl glucoside, 0.05 mass% or more and 10.0 mass% or less are preferable with respect to all the cosmetics. If it is less than 0.05 mass%, moisture retention may be inadequate, and when it exceeds 10.0 mass%, it is unpreferable since it is sticky.
본 발명의 화장료에는, 통상 화장료에 사용되는 성분을 배합할 수 있고, 다가 알코올, 당, 유제, 계면활성제, 수용성 고분자, 유기 분체, 무기 분체, 향료, pH 조정제, 방부제, 비타민 등의 미용성분을 함유시킬 수 있다.In the cosmetics of the present invention, components commonly used in cosmetics can be blended, and cosmetic ingredients such as polyhydric alcohols, sugars, emulsions, surfactants, water-soluble polymers, organic powders, inorganic powders, flavoring agents, pH adjusters, preservatives, and vitamins are used. It can be contained.
본 발명의 화장료는 주로 피부에 적용되고, 피부의 보습에 효과를 갖는 것으로, 피부 외용제라면 의약부외품도 포함된다.The cosmetics of the present invention are mainly applied to the skin, have an effect on moisturizing the skin, and include quasi-drug products if the external preparation for the skin.
본 발명의 화장료의 제형으로서는, 화장수, 유액, 크림, 수성 겔, 팩 등을 들 수 있고, 유화제형에 대해서는, 수중유(水中油) 유화, 유중수(油中水) 유화 모두 가능하다.Examples of the formulation of the cosmetic of the present invention include a lotion, an emulsion, a cream, an aqueous gel, a pack, and the like, and the oil-in-water emulsification and the water-in-oil emulsification are possible for the emulsifier type.
[실시예][Example]
(각질층 수분량 측정)(Measurement of horny layer moisture content)
1. 실험방법1. Experimental Method
전완(前腕) 내측부를 핸드솝의 거품으로 10회 문지르고, 미지근한 물로 10초 씻어낸다.Rub the inner part of the forearm 10 times with the foam of the hand and rinse with lukewarm water for 10 seconds.
전완의 수분을 닦아내고, 23℃, 상대습도 36%의 환경하에서 20분 안정하게 유지한다.Wipe off the forearm moisture and keep it stable for 20 minutes in an environment of 23 ° C and 36% relative humidity.
좌우 전완에 3 군데씩 2.5 ㎝×2.5 ㎝의 영역을 기록하고, 표 1에 기재된 6시료를 순차 도포하여, 순차적으로, 도포 후 20분, 40분, 60분, 80분, 100분, 120분 후의 각질층 수분량을 측정하였다. 또한, 무도포 부위를 대조로 하여 각질층 수분량을 측정하였다.An area of 2.5 cm × 2.5 cm was recorded in three places on the left and right forearms, and the six samples shown in Table 1 were sequentially applied, and sequentially, 20 minutes, 40 minutes, 60 minutes, 80 minutes, 100 minutes, and 120 minutes after application. The water content of the stratum corneum afterwards was measured. In addition, the moisture content of the stratum corneum was measured with the uncoated area as a control.
시료의 도포방법은, 주걱을 정밀 전자천칭에 올리고, 시료를 10 ㎎ 칭량하여 취하고, 그 주걱을 사용하여 2.5 ㎝×2.5 ㎝의 영역에 도포하였다.In the application method of the sample, a spatula was placed on a precision electronic balance, 10 mg of the sample was weighed out, and applied to an area of 2.5 cm x 2.5 cm using the spatula.
각질층 수분량은 IBS사 제조 SKICON-200을 사용하여, 각 영역에서 5회씩 측정하고, 평균내었다.The stratum corneum moisture content was measured 5 times in each region using SKICON-200 manufactured by IBS, and averaged.
2. 결과2. Results
동일한 시험을, 시료 도포영역의 장소를 바꿔서, 2회 반복하였다. 측정 1회째의 결과를 표 2에, 측정 2회째의 결과를 표 3에 나타낸다. 2회 모두 동일한 경향을 확인할 수 있었다. 또한, 1회째의 결과를 도 1에 그래프로 나타낸다.The same test was repeated twice, changing the place of a sample application | coating area | region. Table 2 shows the results of the first measurement, and Table 3 shows the results of the second measurement. The same tendency was confirmed in both times. In addition, the result of the 1st time is shown graphically in FIG.
폴리옥시에틸렌 메틸글루코시드, 디프로필렌글리콜(DPG), 1,3-부틸렌글리콜(BG)은 모두 보습제이지만, 폴리메타크릴산 메톡시 폴리에틸렌글리콜을 병용했을 때의 각질층 수분량의 증대 효과에 차이가 확인된다. DPG, BG 각각에 대해서, 폴리메타크릴산 메톡시 폴리에틸렌글리콜을 병용하여도 각질층 수분량은 거의 변화하지 않았다. 폴리메타크릴산 메톡시 폴리에틸렌글리콜 단독으로는, 각질층 수분량을 증대시키는 효과는 없는 것으로 생각된다. 한편, 폴리옥시에틸렌 메틸글루코시드와 폴리메타크릴산 메톡시 폴리에틸렌글리콜을 병용하면 각질층 수분량이 현저하게 증대하였다.Polyoxyethylene methyl glucoside, dipropylene glycol (DPG), and 1,3-butylene glycol (BG) are all moisturizers, but there is a difference in the effect of increasing the amount of moisture in the stratum corneum when the polymethacrylate methoxy polyethylene glycol is used in combination. It is confirmed. For each of DPG and BG, even when polymethacrylic acid methoxy polyethylene glycol was used in combination, the moisture content of the stratum corneum was hardly changed. It is thought that polymethacrylic acid methoxy polyethyleneglycol alone does not have an effect of increasing the horny layer moisture content. On the other hand, when polyoxyethylene methyl glucoside and polymethacrylic acid methoxy polyethylene glycol are used together, the moisture content of the stratum corneum was remarkably increased.
(수분 증산량 측정)(Moisture increase amount measurement)
1. 실험방법1. Experimental Method
크림병(개구부의 직경이 4 ㎝)에 정제수를 10 mL 넣는다.10 mL of purified water is added to a cream bottle (opening diameter of 4 cm).
병의 가장자리에 풀을 칠하고, 여과지(No.2)를 접착한다.Glue the edge of the bottle and glue the filter paper (No. 2).
여과지의 중심부에 0.5 mL의 시료를 적하하였다. 시료는 여과지 전체에 자연스럽게 퍼진다. 시료는 표 4에 나타낸다.0.5 mL of sample was added dropwise to the center of the filter paper. The sample spreads naturally across the filter paper. Samples are shown in Table 4.
정밀 전자천칭을 사용하여 시료를 여과지에 적하한 크림병의 총 중량을 측정한다.A precision electronic balance is used to measure the total weight of the cream bottle in which the sample is added to the filter paper.
항온항습실(23~24℃, 상대습도 33%)에서 6시간 방치하고, 크림병의 총 중량을 측정하여, 원래 중량과의 차로부터 수분 증산량을 구하였다.It was left to stand in a constant temperature and humidity room (23-24 degreeC, 33% of a relative humidity) for 6 hours, the total weight of the cream bottle was measured, and the amount of moisture evaporation was calculated | required from the difference with original weight.
2. 결과2. Results
수분 증산량의 결과를 도 2에 나타낸다. 폴리옥시에틸렌 메틸글루코시드와 폴리메타크릴산 메톡시 폴리에틸렌글리콜을 병용한 것은 우수한 수분 증산 억제 효과를 나타내었다.The result of the amount of water evaporation is shown in FIG. The combination of polyoxyethylene methylglucoside and polymethacrylic acid methoxy polyethyleneglycol showed an excellent effect of inhibiting water transpiration.
처방예 1 에몰리언트(emollient) 화장수Prescription Example 1 emollient lotion
(배합성분) (질량%)(Compound Component) (Mass%)
1. 합성예 2의 고분자 0.51. Polymer 0.5 of Synthesis Example 2
2. 메틸글루세스-10 5.02. Methylgluses-10 5.0
(폴리옥시에틸렌 메틸글루코시드) (Polyoxyethylene Methyl Glucoside)
3. 디스테아르산 폴리글리세릴-10 0.23. Distearic Acid Polyglyceryl-10 0.2
4. 스테아르산 폴리글리세릴-10 0.44. Stearic Acid Polyglyceryl-10 0.4
5. 올리브 오일 3.05. Olive Oil 3.0
6. 1,3-부틸렌글리콜 4.06. 1,3-butylene glycol 4.0
7. 크산탄검 0.17. Xanthan Gum 0.1
8. 1,2-펜탄디올 1.08. 1,2-pentanediol 1.0
9. 구연산 삼나트륨 0.049. Trisodium Citrate 0.04
10. 구연산 0.0110. Citric Acid 0.01
11. 페녹시에탄올 0.211.Phenoxyethanol 0.2
12. 정제수 잔여12. Purified water residual
본 화장수는 보습성이 높아, 피부 거칠어짐 개선, 방지 효과가 우수하다.
This lotion has high moisture retention and is excellent in improving skin roughness and preventing effects.
처방예 2 미용액Prescription 2 Serum
(배합성분) (질량%)(Compound Component) (Mass%)
1. 합성예 2의 고분자 2.01. Polymer 2.0 of Synthesis Example 2
2. 메틸글루세스-20 8.02. Methylgluses-20 8.0
3. 디스테아르산 폴리글리세릴-10 0.63. Distearic Acid Polyglyceryl-10 0.6
4. 스테아르산 폴리글리세릴-10 1.44. Stearic Acid Polyglyceryl-10 1.4
5. 정제수 0.25. Purified Water 0.2
6. 올리브 오일 4.06. Olive Oil 4.0
7. 호호바 오일 4.07. Jojoba Oil 4.0
8. 디프로필렌글리콜 3.08. Dipropylene Glycol 3.0
9. 카르복시비닐 폴리머 0.19. Carboxyvinyl Polymer 0.1
10. 1,2-펜탄디올 1.010. 1,2-pentanediol 1.0
11. 엘라스틴 0.111.Elastin 0.1
12. 히알루론산 0.112. Hyaluronic Acid 0.1
13. 콜라겐 0.113. Collagen 0.1
14. 수산화칼륨 0.0314. Potassium hydroxide 0.03
15. 정제수 잔여15. Purified water residual
본 미용액은 보습성이 높아, 피부 거칠어김 개선, 방지 효과가 우수하다.This cosmetic liquid has high moisture retention and is excellent in improving skin roughness and preventing effects.
Claims (4)
폴리메타크릴산 메톡시 폴리에틸렌글리콜(A)은, 폴리스티렌 환산 수 평균 분자량 1000~100000인 것을 특징으로 하는 화장료.The method according to claim 1 or 2,
Polymethacrylate methoxy polyethyleneglycol (A) is polystyrene conversion number average molecular weight 1000-100000, The cosmetics characterized by the above-mentioned.
폴리옥시에틸렌 메틸글루코시드(B)는, 메틸글루코오스의 폴리에틸렌글리콜에테르이고, 다음의 화학식으로 표시되는 것을 특징으로 하는 화장료.
4. The method according to any one of claims 1 to 3,
Polyoxyethylene methyl glucoside (B) is polyethyleneglycol ether of methyl glucose, and is represented by following chemical formula.
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