KR20080112884A - Breathing gas complex analyzer - Google Patents
Breathing gas complex analyzer Download PDFInfo
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- KR20080112884A KR20080112884A KR1020070061892A KR20070061892A KR20080112884A KR 20080112884 A KR20080112884 A KR 20080112884A KR 1020070061892 A KR1020070061892 A KR 1020070061892A KR 20070061892 A KR20070061892 A KR 20070061892A KR 20080112884 A KR20080112884 A KR 20080112884A
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- South Korea
- Prior art keywords
- gas
- sensor
- carbon monoxide
- hydrogen sulfide
- aerobic
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- 230000029058 respiratory gaseous exchange Effects 0.000 title abstract 5
- 239000007789 gas Substances 0.000 claims abstract description 46
- RWSOTUBLDIXVET-UHFFFAOYSA-N Dihydrogen sulfide Chemical compound S RWSOTUBLDIXVET-UHFFFAOYSA-N 0.000 claims abstract description 14
- 229910000037 hydrogen sulfide Inorganic materials 0.000 claims abstract description 14
- UGFAIRIUMAVXCW-UHFFFAOYSA-N Carbon monoxide Chemical compound [O+]#[C-] UGFAIRIUMAVXCW-UHFFFAOYSA-N 0.000 claims abstract description 13
- 229910002091 carbon monoxide Inorganic materials 0.000 claims abstract description 13
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 4
- 238000002347 injection Methods 0.000 claims description 3
- 239000007924 injection Substances 0.000 claims description 3
- 238000012545 processing Methods 0.000 claims description 3
- 238000004868 gas analysis Methods 0.000 claims description 2
- 230000000241 respiratory effect Effects 0.000 claims 1
- 108010003320 Carboxyhemoglobin Proteins 0.000 abstract 1
- 230000000391 smoking effect Effects 0.000 description 9
- 238000012360 testing method Methods 0.000 description 8
- 238000000034 method Methods 0.000 description 7
- 206010006326 Breath odour Diseases 0.000 description 5
- 239000004065 semiconductor Substances 0.000 description 5
- 102000001554 Hemoglobins Human genes 0.000 description 2
- 108010054147 Hemoglobins Proteins 0.000 description 2
- 238000007664 blowing Methods 0.000 description 2
- 230000037029 cross reaction Effects 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- LJSQFQKUNVCTIA-UHFFFAOYSA-N diethyl sulfide Chemical compound CCSCC LJSQFQKUNVCTIA-UHFFFAOYSA-N 0.000 description 2
- 208000010643 digestive system disease Diseases 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 229910052739 hydrogen Inorganic materials 0.000 description 2
- 239000001257 hydrogen Substances 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 206010006322 Breath holding Diseases 0.000 description 1
- 241000208125 Nicotiana Species 0.000 description 1
- 235000002637 Nicotiana tabacum Nutrition 0.000 description 1
- 208000025157 Oral disease Diseases 0.000 description 1
- UCKMPCXJQFINFW-UHFFFAOYSA-N Sulphide Chemical compound [S-2] UCKMPCXJQFINFW-UHFFFAOYSA-N 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 230000002596 correlated effect Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 235000019621 digestibility Nutrition 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 208000030194 mouth disease Diseases 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 239000000779 smoke Substances 0.000 description 1
- 230000005586 smoking cessation Effects 0.000 description 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/4162—Systems investigating the composition of gases, by the influence exerted on ionic conductivity in a liquid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
- A61B5/082—Evaluation by breath analysis, e.g. determination of the chemical composition of exhaled breath
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/0004—Gaseous mixtures, e.g. polluted air
- G01N33/0009—General constructional details of gas analysers, e.g. portable test equipment
- G01N33/0027—General constructional details of gas analysers, e.g. portable test equipment concerning the detector
- G01N33/0036—Specially adapted to detect a particular component
- G01N33/004—Specially adapted to detect a particular component for CO, CO2
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/0004—Gaseous mixtures, e.g. polluted air
- G01N33/0009—General constructional details of gas analysers, e.g. portable test equipment
- G01N33/0027—General constructional details of gas analysers, e.g. portable test equipment concerning the detector
- G01N33/0036—Specially adapted to detect a particular component
- G01N33/0044—Specially adapted to detect a particular component for H2S, sulfides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/497—Physical analysis of biological material of gaseous biological material, e.g. breath
-
- G01N33/4975—
Abstract
Description
최근 질병의 진단방법이 발달하면서 환자가 내쉬는 숨(호기가스)를 분석하여 구강With the recent development of the diagnosis method of the disease, the patient breathes out the breath (exhalation gas)
이나 소화계통 질환을 점검하는 기술이 개발되고 있다. 이러한 호기 가스분석장치는 보통 입냄새(구취) 측정기라고 불리우며 황화수소 계열의 가스를 측정하는 장비가 사용되어왔으며, 최근에는 반도체 센서를 이용한 간편한 입냄새 측정기들이 제조/판매되고 있는데, 이들 제품에 사용되는 센서들은 가스 분석기능이 약해 에틸황화물, 메틸아르캅탄, 수소황화물등의 휘발성 황화가스를 총량적으로 검지하기 때문에, 각각의 가스량을 검지함으로서 특정 질환을 탐지해내는 것은 불가능하다. 그러므로 이러한 기기들은 단지 입냄새 정도를 측정하는 장비로서의 기능만을 수행한다는 문제점이 있었다.However, techniques for detecting digestive system diseases are being developed. Such an aerobic gas analyzer is commonly referred to as a breath odor detector and has been used to measure hydrogen sulfide gas. Recently, simple breath detectors using semiconductor sensors have been manufactured and sold. The sensors are weak in gas analysis and detect total amount of volatile sulfide gases such as ethyl sulfide, methyl arcaptan and hydrogen sulfide. Therefore, it is impossible to detect specific diseases by detecting each gas amount. Therefore, these devices have a problem that only serves as a device for measuring the degree of bad breath.
한편 호기성 가스를 측정하는 장비로는 호기중 CO가스를 분석하는 호기중 co측정장비가 있다. 이러한 장비는 호기중의 일산화탄소 농도가 헤모그로빈과 결합한 일산화탄소농도와 일정한 상관관계가 있다는 사실에 착안하여, 담배연기에 의해 일산화탄소를 많이 흡입하는 흡연자의 경우 비흡연자보다 호기중에 일산화탄소 농도가 높다는 것을 이용하여 흡연정도를 측정하는 장비로 사용되고 있다.On the other hand, the equipment for measuring aerobic gas is an aerobic co measuring equipment for analyzing the CO gas in the exhalation. This equipment focuses on the fact that the concentration of carbon monoxide in exhalation is consistently correlated with the concentration of carbon monoxide combined with hemoglobin, and that smokers who inhale a lot of carbon monoxide by tobacco smoke use higher concentrations of carbon monoxide in exhalation than non-smokers. It is used as a measuring device.
호기중 CO측정기는 세계적인 금연열풍에 힘입어 2005년부터 판매량이 꾸준히 늘고 있다. 그러나 기존의 CO측정기는 담배를 피우는 습관을 검지할 수는 있으나, 흡연의 해악을 설명하는 장비로서는 부족함이 있다. 즉 흡연이 우리몸에 끼친 악영향을 직접적으로 보여주지는 못하는 것이다.. In-flight CO meter sales have been steadily increasing since 2005, fueled by the global ban on smoking cessation. However, the existing CO meter can detect the habit of smoking, but there is a lack of equipment to explain the harm of smoking. In other words, smoking does not directly show the adverse effects on our body.
본 발명에서는 흡연습관 여부만이 아니라 흡연이 우리몸에 끼친 해악을 설명하기 위해, 호기가스를 측정하여 호기중 일산화탄소의 농도와 함께 헤모그로빈중 일산화탄소와 결합한 정도를 나타내는 COHB 값을 나타내 줌과 동시에, 흡연자의 호기가스중에 포함된 황화수소가스를 측정하여 흡연자의 입냄새가 심하다는 것을 보여줄 수 있도록 CO가스 분석기가 입냄새 측정기를 겸할 수 있도록 구성한 것을 제공코자 한다. In the present invention, in order to explain not only smoking habits but also the harms caused by smoking, the aerobic gas is measured to show the COHB value indicating the degree of carbon monoxide combined with hemoglobin in combination with the concentration of carbon monoxide in the exhalation. To measure the hydrogen sulfide gas contained in the exhalation gas of the gas to provide a smoker's bad breath to provide a configuration that the CO gas analyzer can also function as a breath tester.
본발명은 호기가스중의 일산화탄소,황화수소 가스의 농도를 측정하여, 흡연 여부 및 입냄새정도를 체크할 수 있는 호기가스 측정기에 관한 것이다. The present invention relates to an exhalation gas measuring instrument that can check the concentration of carbon monoxide, hydrogen sulfide gas in the exhalation gas, and check the degree of smoking and bad breath.
본 발명의 기본 구성은 적어도 1개 이상의 가스를 측정할 수 있는 복수의 센서부와 조작부와 디스플레이부와 중앙처리장치와 전원부로 구성되어 있으며, 센서부에는 적어도 일산화탄소와 황화수소를 센싱할 수 있는 센서를 가지고 있는 것을 특징으로 한다.The basic configuration of the present invention is composed of a plurality of sensor units, an operation unit, a display unit, a central processing unit, and a power supply unit capable of measuring at least one or more gases, and the sensor unit includes a sensor capable of sensing at least carbon monoxide and hydrogen sulfide. It is characterized by having.
가스를 센싱하는 센서는 전기화학방식이나 반도체 방식이 모두 사용될 수 있으며,Gas sensing sensor can be used both electrochemical and semiconductor methods,
검출속도를 빠르게 하기 위해서는 반도체 센서를 사용하는 것이 바람직하다.In order to speed up the detection, it is preferable to use a semiconductor sensor.
센서에서 발생된 변화는 통상 저항의 변화로 표현되는데, 이러한 변화치가 미미하기 때문에 본 발명에서는 측정기에서 통상적으로 사용하는 것과 같이 출력신호를 일정비율로 증폭시킨 후, 이 값을 해석하여 호기가스중의 특정가스의 농도를 측정하게 된다.본 발명의 실시예에서는 반도체 타입의 일산화탄소센서,수소가스센서, 황화수소 센서를 사용한다. 황화수소 가스 센서는 황화수소 농도 (PPB) 에틸황화물, 메틸아르캅탄, 수소황화물센서로 입냄새 등급을 나타내기 위해 사용한다.The change generated in the sensor is usually expressed as a change in resistance, and since the change is small, the present invention amplifies the output signal at a constant ratio as is commonly used in measuring devices, and then interprets the value to analyze the value in the aerobic gas. The concentration of the specific gas is measured. In the embodiment of the present invention, a semiconductor type carbon monoxide sensor, a hydrogen gas sensor, and a hydrogen sulfide sensor are used. The hydrogen sulfide gas sensor is used to indicate the breath grade with hydrogen sulfide concentration (PPB) ethylsulfide, methylarcaptan and hydrogen sulfide sensors.
이들 3개 센서에서 나온 출력은 증폭기록되고 이 기록은 검사의 오차를 줄이기 위해, 검사 시작후 일정 시간 간격으로 평균 출력치를 환산하고, 검사 시작부터 검사가 끝날 때까지의 값들중 가장 최대값을 취한다. 중앙처리장치에서는 이 최대 값에서 각 가스 및 센서별로 상호 교차반응값을 가감한 후, 최종적으로 각 센서의 최대 출력값을 결정한다. The outputs from these three sensors are amplifier-locked and the record is converted to the average output at regular time intervals after the start of the test, taking the maximum of the values from the start of the test to the end of the test to reduce errors in the test. do. The central processing unit subtracts the cross-reaction value for each gas and sensor from this maximum value, and finally determines the maximum output value of each sensor.
상기 출력값은 각 센서의 농도 출력 특성그래프에 의해 가스농도로 환산되어 디스플레이부에 표시된다.The output value is converted into gas concentration by the concentration output characteristic graph of each sensor and displayed on the display unit.
센서의 출력값을 그래프로 나타내도 무방하다.The output value of the sensor may be displayed graphically.
본 발명의 또다른 특징중의 하나는 호기가스 성분을 분석하기위해 센서부분으로 호기를 불어 넣는 방법이, 종래 모든 제품들을 1가지 방법만을 사용하고 있음에 반해 본 발명의 호기가스 측정기는 음주 측정기처럼 별도의 마우스피스가 없이 호기가스 주입부에 입김을 불어 넣어 측정하는 모드와 마우스피스를 사용하는 모드로 구분한 다. 마우스피스를 사용하지 않을 경우에는 호기가스에 주변의 공기가 같이 주입되기 때문에 목적 가스의 농도가 떨어지게 된다. 그러므로 마우스피스를 사용하지 않을 경우, 마우스피스를 사용할 경우보다 표시값을 높여야 한다. 얼마나 높이는가의 정도는 500%범위내에서 실험에 의해 결정해야 할 것이다. One of the features of the present invention is that the method of blowing air into the sensor part to analyze the air gas components, while all the conventional products use only one method, the air gas meter of the present invention is like a breathalyzer There is no separate mouthpiece, it is divided into the mode of blowing breath into the inhalation gas injection unit and the mode using the mouthpiece. When the mouthpiece is not used, the concentration of the target gas decreases because the surrounding air is injected into the exhalation gas together. Therefore, when the mouthpiece is not used, the display value should be higher than when the mouthpiece is used. The degree of height increase should be determined by experiment within 500% range.
또한 본기기는 사용의 편리성을 높이기 위해 검사모드와 설정모드를 구분한다. 검사모드에서는 검사를 위한 일련의 절차대로만 기기가 움직인다. In addition, the instrument distinguishes between the test mode and the setting mode for ease of use. In the test mode, the instrument moves only through a series of procedures for inspection.
검사 시작단계와 최대 들숨상태로 15-20초간 숨홀딩 단계와 숨내쉬기 단계 및 최대값표시단계 결과 디스플레이 단계의 절차만이 반복적으로 디스플레이된다. Only the procedure of the breath holding step, the exhaling step, and the maximum value display step result display step for 15-20 seconds with the test start step and the maximum inspiration state are repeatedly displayed.
한편 설정모드에서는 대기시간 조정, 캘리브레이션 모드, 마우스피스 사용여부, 장비 작동음 소거여부, 신속검사 모드 등을 설정할 수 있다.On the other hand, in the setting mode, it is possible to set the standby time adjustment, the calibration mode, the use of the mouthpiece, the mute of the operation sound and the quick test mode.
또한 본 발명의 호기가스 측정기에서는 USB 포트를 이용한 컴퓨터를 이용하여 장비제어, 데이터 송수신이 가능하고 , 결과 분석프로그램에 의해 검사 결과를 pc상에서 분석하고 진단할 수 있다.In addition, the exhalation gas measuring instrument of the present invention can be used to control the equipment, data transmission and reception using a computer using a USB port, and the analysis results can be analyzed and diagnosed on the PC by the result analysis program.
본 발명의 호기가스 측정장비에 대한 개념도는 실시예에 표시된 바와 같다.The conceptual diagram of the aerobic gas measuring instrument of this invention is as shown in the Example.
본 발명의 호기가스 측정기는 co 검지 센서를 이용한 흡연측정기능, 반도체 센서를 이용한 황화수소계열 입냄새 측정, 장비의 수소 교차반응 보정 및 우유 소화능력을 점검하기 위한 수소계열 가스를 측정하는 등의 호기가스를 다양하게 분석함으로서 흡연 측정기능을 물론 흡연 예방기능과 함께, 구강 및 소화기 계열 질병The aerobic gas measuring instrument of the present invention is an aerobic gas such as a smoking measurement function using a co-detection sensor, a hydrogen sulfide-based breath odor measurement using a semiconductor sensor, hydrogen cross-reaction correction of equipment and a hydrogen-based gas for checking milk digestibility By analyzing the various types of smoking, as well as smoking prevention function, along with oral and digestive diseases
에 대한 종합 판정 장비로서 사용이 가능한 유용한 발명이다It is a useful invention that can be used as a comprehensive judgment equipment for
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN107449808A (en) * | 2017-09-14 | 2017-12-08 | 杭州麦乐克科技股份有限公司 | A kind of human exhaled breath's analyzer |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN107449808A (en) * | 2017-09-14 | 2017-12-08 | 杭州麦乐克科技股份有限公司 | A kind of human exhaled breath's analyzer |
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