KR20050001556A - The composition of materials to prevent the adult disease and reduce the obesity - Google Patents

The composition of materials to prevent the adult disease and reduce the obesity Download PDF

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KR20050001556A
KR20050001556A KR1020030041761A KR20030041761A KR20050001556A KR 20050001556 A KR20050001556 A KR 20050001556A KR 1020030041761 A KR1020030041761 A KR 1020030041761A KR 20030041761 A KR20030041761 A KR 20030041761A KR 20050001556 A KR20050001556 A KR 20050001556A
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acid
parts
vitamin
dopamine
drug
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서왕식
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서왕식
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/40—Cornaceae (Dogwood family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/46—Eucommiaceae (Eucommia family), e.g. hardy rubber tree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Alternative & Traditional Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

PURPOSE: Provided is a composition for improving adult diseases and obesity which is prepared by extracting active ingredients from medicinal plants, and concentrating and drying the extract. CONSTITUTION: The composition for improving adult diseases and obesity is characterized by containing pharmacologically effective ingredients extracted from medicinal plants with dopamine, and pharmaceutically acceptable carriers. The pharmacologically effective ingredients include (1) ginsenoside Ro, Ra-Rh, panaxynol, β-elemene, β-sitosterol, amino acids, peptides, maltol, choline, allylcysteine sulfoxide, capsaicin, dihydro-capsaicin, iso-undecoyl vanillylamide, capsanthin, carotene, vitamin C, starch, fatty oil, coixol, sterol, amino acid, vitamin B1, coixenolide, D-glucose, D-mannose, phosphorus, Iodine, β-carotin, fucoidan, laminarin, mannitol, polyphenol, tannin, catechin and glucosamine; (2) gutta-percha, ketose, chlorogenic acid, pectin, acanthoside A, B, C, D, daucosterol, polyacetylenes, ziliodendrin, β-sitosterol, campesterol, ethoxy-hydroxy-benzoic acid, carthamin, safflor yellow, carthamidin, lignan, linoleic acid, γ-linolenic acid, cinnamic aldehyde, cinnamyl acetate, phenylpropyl acetate, betaine, vitamin B1, zeaxanthin, physalien, mucin, decursin, decursinol, nodakenin, α-pinene, limonene, β-eudesmo and elemol; (3) morroniside, loganin, cornin, gallic acid, tartaric acid, malic acid, gyrophoric acid, lecanoric acid, nelumbine, zotusine, liensinine, pronuciferine, cimitin, cimicifugin, salicylic acid, fatty acid, chrysophanol, emodin, rhein, fatty oil, protein, costuslactone, costic acid, costol, α-, β-costen, saussurine, inulin, glycyrrhizin, liquiritigenin, glucose, mannitol, malic acid and L-asparagine.

Description

성인병(成人病) 예방 및 비만증(肥滿症) 개선제 조성물{The composition of materials to prevent the adult disease and reduce the obesity}The composition of materials to prevent the adult disease and reduce the obesity}

본 발명은 약용 식물의 약성분에 도파민(dopamine)을 첨가하여 3단계의 공정과정을 거쳐 배합 및 법제된 제약 상의 허용가능한 조성물에 관한 것이다. 특히 아래 1), 2), 3항의 약성분이 상호 상승작용(相乘作用)을 할 수 있도록 동과피(Benincasae pericarpium) 추출물과 하이드록시 시트릭산(Hydroxy citric acid)을 포함하여 조성한 것이다.The present invention relates to a pharmaceutical acceptable composition formulated and formulated through a three step process by adding dopamine to the medicinal components of a medicinal plant. Particularly, the ingredients 1), 2) and 3 below are composed of copper extract (Benincasae pericarpium) extract and hydroxy citric acid (Hydroxy citric acid) to enable synergistic interaction (相乘 作用).

1) 1단계는 약용 식물의 약성분을 50메쉬(mesh)로 절편한 홍삼(紅蔘 ; 주성분 - Ginsenoside Ro, Ra∼Rh, panaxynol, β-Elemene, β-sitosterol, Amino acids, peptides, Maltol, choline), 대산(大蒜 ; 주성분 - Allylcysteine Sulfoxide), 고추(capsicum;주성분 - Capsaicin, Dihydro-capsaicin, Iso-undecoyl vanillylamide, capsanthin, carotene, vitamin C), 의이인(薏苡仁 ; 주성분 - starch, Fatty oil, coixol, sterol, Amino acid, vitamin B1, coixenolide), 곤약(; 주성분 - D-Glucose, D-mannose), 다시마(Kelp : (학명) LaminariaJaponica ; 주성분 - phosphorus, Iodine, β-carotin, fucoidan, Laminarin, mannitol), 녹차(綠茶 ; 주성분 - polyphenol, Tannin, catechin), 키토산(chitosan ; 주성분 - Glucosamin)을 각각 평량하고 취하여 추출(抽出)한 약성분이다.1) In the first step, red ginseng (약; main components-Ginsenoside Ro, Ra-Rh, panaxynol, β-Elemene, β-sitosterol, Amino acids, peptides, Maltol, choline), Daesan (大蒜; main ingredient-Allylcysteine Sulfoxide), Capsicum; main ingredient-Capsaicin, Dihydro-capsaicin, Iso-undecoyl vanillylamide, capsanthin, carotene, vitamin C) coixol, sterol, Amino acid, vitamin B 1 , coixenolide), konjac ( ; Main ingredients-D-Glucose, D-mannose), kelp (Kelp: Laminaria Japonica; main ingredients-phosphorus, Iodine, β-carotin, fucoidan, Laminarin, mannitol), green tea (주 茶; main ingredients-polyphenol, Tannin, catechin), Chitosan (main ingredient-Glucosamin) is a pharmaceutical ingredient extracted and weighed, respectively.

2) 2단계는 약용 식물을 1)에서와 같이 두충(社沖 ; 주성분 - Gutta-percha, ketose, chlorogenic acid, pectin), 오가피(五加皮 ; 주성분 - Acanthoside A, B, C, D, Daucosterol, polyacetylenes, ziliodendrin, β-sitosterol, campesterol, Ethoxy-hydroxy-benzoic acid), 홍화(紅花 ; 주성분 - carthamin, safflor yellow, carthamidin, Lignan), 달맞이꽃(evening primrose 또는 월견초(月見草) ; 주성분 - Linoleic acid, γ-Linolenic acid), 육계(肉桂 ; 주성분 - Cinnamic aldehyde, cinnamyl acetate, phenylpropyl acetate), 구기자(枸杞子) ; 주성분 - Betaine, vitamin B1, Zeaxanthin, physalien), 위유(; 주성분 - Mucin), 당귀(當歸 ; 주성분 - Decursin, Decursinol, Nodakenin 등의 coumarin 유도체와 α-pinene, Limonene, β-Eudesmol, Elemol 등을 주로한 정유)를 각각 평량하고 취하여 추출한 약성분이다.2) In the second step, medicinal plants are treated with the same insects as in 1), with the main components-Gutta-percha, ketose, chlorogenic acid, pectin), Ogapi (五加皮; main components-Acanthoside A, B, C, D, Daucosterol , polyacetylenes, ziliodendrin, β-sitosterol, campesterol, Ethoxy-hydroxy-benzoic acid, safflower (주 花; main ingredient-carthamin, safflor yellow, carthamidin, Lignan), evening primrose or Evening Primrose; main ingredient-Linoleic acid , γ-Linolenic acid), Broiler (肉桂; main components-Cinnamic aldehyde, cinnamyl acetate, phenylpropyl acetate), Gojija (枸杞 子); Main ingredients-Betaine, vitamin B 1 , Zeaxanthin, physalien) ; Main ingredient-Mucin), Angelica (當歸; main ingredient-coumarin derivatives such as Decursin, Decursinol, Nodakenin, and essential oils mainly composed of α-pinene, Limonene, β-Eudesmol, Elemol, etc.)

3) 3단계는 1)에서와 같이 산수유(山茱萸 ; 주성분 - Morroniside, Loganin, cornin, Gallic acid, Tartaric acid, Malic acid), 영지(靈芝 ; 주성분 - Gyrophoric acid, Lecanoric acid), 연자육(蓮子肉 ; 주성분 - Nelumbine, Zotusine, Liensinine, pronuciferine), 승마(升麻 ; 주성분 - Cimitin,Cimicifugin, Salicylic acid, Fatty acid), 하수오(何首烏 ; 주성분 - Chrysophanol, Emodin, Rhein), 해송자(海松子 ; 주성분 - Fatty oil, protein), 목향(木香 ; 주성분 - Costuslactone, Costic acid, costol, α-, β-costen, saussurine, Inulin, 樹脂), 감초(甘草 ; 주성분 - Glycyrhizin, Liquiritigenin, Glucose, Mannitol, Malic acid, ℓ-Asparagin)를 각각 평량하고 취하여 추출한 약성분이다.3) In step 3, as in 1), cornus (山茱萸; main ingredient-Morroniside, Loganin, cornin, Gallic acid, Tartaric acid, Malic acid), Ganoderma lucidum (靈 芝; main ingredient-Gyrophoric acid, Lecanoric acid), lotus root (蓮 子 肉; Main ingredient-Nelumbine, Zotusine, Liensinine, pronuciferine), Horse riding (升麻; main ingredient-Cimitin, Cimicifugin, Salicylic acid, Fatty acid), Sewage (何首烏; main ingredient-Chrysophanol, Emodin, Rhein) oil, protein), Mokyang (木香; main ingredient-Costuslactone, Costic acid, costol, α-, β-costen, saussurine, Inulin, 樹), licorice (甘草; main ingredient-Glycyrhizin, Liquiritigenin, Glucose, Mannitol, Malic acid, L-Asparagin) is a weak ingredient extracted by weighing each one.

본 발명의 조성물은 1단계, 2단계, 3단계의 공정과정을 거쳐 약용 식물의 100여 종류의 약성분이 상호 상승작응(相乘作用)을 할 수 있도록 도파민(dopamine)과 동과피(Benincasae pericarpium) 추출물 그리고 하이드록시 시트릭산(Hydroxy citric acid)을 가하여 에틸알콜( Ethyl alcohol)로 추출(抽出)하여 숙성(熟成) 제조된 조성물이다. 약용 식물의 약효 성분은 수용성(水溶性)과 유용성(油溶性)으로 구성되어있다. 종래는 약용 식물을 적당히 절편하여 약탕기에서 물을 붓고 끓여서 일정량으로 될 때 마포청에 넣고 짜서 복용하였다. 따라서 약용 성분인 유용성은 복용 할 수가 없었다. 본 발명에서는 발명의 구성에서와 같이 약용 식물을 절편하여 법제(法制)＜약효성분중의 독성을 제거하고 약의 성분을 향상시키기 위한 비법＞한 후 50메쉬(mesh) 정도 분말로 하고 도파민(dopamine = 3-Hydroxytyramine Hydrochloride)과 동과피(Benincasae pericarpium) 추출물 그리고 하이드록시 시트릭산(Hydroxy citric acid)을 가하여 에틸알콜(Ethyl alcohol)로 추출 농축 건조하기 때문에 약용 식물이 가지고 있는 수용성 및 유용성의 약성분이 거의 추출되는 것이다. 또한 200메쉬 이상 분말로 하여 정제나 캅셀(capsule)로 하기 때문에 사람이 복용하기 쉬운 것이다. 종래의 약탕기에서 다려 복용한 것보다는 약효가 월등한 것이다. 또한 도파민(dopamine)을 첨가하여 약효성분이 인체에 적용할 때 현저한 심혈관계 및 신장에 대한 혈액순환의 효과가 크게 향상됨을 발견하였다.The composition of the present invention is a dopamine (dopamine) and copper skin (Benincasae pericarpium) so that more than 100 kinds of medicinal components of the medicinal plant can be synergistically synergistic (Step 1, 2, 3 steps) ) Extract and hydroxy citric acid (Hydroxy citric acid) was added to extract the ethyl alcohol (Ethyl alcohol) (抽出) to produce a composition (maturation). The active ingredient of a medicinal plant is composed of water-soluble and oil-soluble. Conventionally, medicinal plants are appropriately sliced, poured into a boiling water bath, boiled, and brought to Mapocheong when a certain amount has been taken and squeezed. Therefore, the availability of medicinal ingredients could not be taken. In the present invention, as in the composition of the invention by cutting the medicinal plants (legule) <secretion to remove the toxicity in the active ingredient and improve the components of the drug> and then to about 50 mesh (dopamine) powder as dopamine (dopamine) = It is extracted and dried with ethyl alcohol by adding 3-Hydroxytyramine Hydrochloride, Benincasae pericarpium extract, and hydroxy citric acid, so that the water-soluble and useful medicinal ingredients of medicinal plants It is almost extracted. In addition, since it is a powder or tablet (capsule) to more than 200 mesh powder, it is easy for human to take. The drug effect is superior to that taken in the conventional medicine bath. In addition, it was found that the addition of dopamine (dopamine) significantly improved the effects of blood circulation on the cardiovascular system and kidneys when the drug was applied to the human body.

본 발명의 당초 개발 목표는 다음과 같다.Initial development goals of the present invention are as follows.

이뇨작용(利尿作用), 강심작용(强心作用), 혈당저하작용(血糖底下作用), 신경계흥분작용(神經系興奮作用), 혈관확장작용(血管擴張作用), 혈압강하작용(血壓降下作用), 진정작용(鎭靜作用), 자양강장작용(滋養强壯作用), 간세포신생촉진작용(肝細胞新生促進作用), 항균작용(抗菌作用), 거담작용(祛痰作用), 해독작용(解毒作用), 콜레스테롤저하작용(Cholesterol 低下作用), 항바이러스작용(抗 virus 作用), 항결핵작용(抗結核作用), 위산분비억제작용(胃酸分泌抑制作用), 장연동촉진작용(陽動促進作用), 혈액순환개선작용(血液循環改善作用), 청혈작용(淸血作用), 정력증강(精力增强), 당뇨(糖尿), 중풍(中風), 성인병(成人病) 예방 및 비만증(肥滿症) 개선작용 등을 목표(目標)로 연구 개발한 약품이다.Diuretic effect (利 尿 作用), cardiac action (强 心 作用), hypoglycemic action (血糖 底下 作用), nervous system excitability (神經 系 興奮 作用), vasodilation (血管 擴張 作用), blood pressure lowering action (血壓 降下 作用) ), Sedation (鎭 靜 作用), nourishing tonic (滋養 强壯 作用), hepatocellular proliferation (肝 細胞 新生 促進 作用), antibacterial (抗菌 作用), expectoration (祛痰 作用), detoxification (解毒) Cholesterol lowering effect, antiviral effect, anti-tuberculosis effect, gastric acid secretion inhibitory effect, intestinal synchrony promotion effect 動 促進 作用, blood circulation improvement (血液 循環 改善 作用), blood clotting (淸 血 作用), energetic enhancement (精力 增强), diabetes (중), stroke, adult disease (成人 病) prevention and obesity ( It is a drug that has been researched and developed with the goal of improving the effect of 肥 滿 症.

본 발명의 약 성분에는 자양강장작용, 혈압강하작용, 혈당저하작용, 장연동촉진작용, 콜레스테롤 저하작용, 체지방 분해작용, 혈액정화 및 혈액순환 개선작용 등 100여 종류의 약성분이 포함되어 있다.The drug component of the present invention contains about 100 kinds of drug components such as nourishing tonic action, blood pressure lowering action, hypoglycemic action, intestinal interlocking action, cholesterol lowering action, body fat decomposition action, blood purification and blood circulation improvement.

이와 같이 100여 종류의 약 성분이 다 인체에 유효 작용케 함은 매우 어려운 과제였다. 그러나 약용식물을 먼저 법제 하였고 도파민(dopamine)과 동과피(Benincasae pericarpium) 추출물 그리고 하이드록시 시트릭산(Hydroxycitric acid)을 첨가하므로서 완전히 해결하였다. 또한 약성분을 더 완벽하게 처리하기 위하여 추출전 50메쉬 정도의 분말로 하여 에틸알콜(Ethyl alcohol)과 접촉면을 넓혀 거의 완전히 추출하였다. 그러나 에틸알콜은 인화성(引火性) 물질로서 화기에 매우 위험한 것이다. 따라서 30-60% 알콜로 조정 사용하였다. 약성분 액기스의 농축 과정에서 증발하는 알콜은 공해의 위험성이 상존한다. 이것은 대량 생산시 시설을 보완하여 알콜을 회수하여 사용하면 되는 것이다. 특히 농축액을 건조하는 과정이 어려웠다. 섭씨 120℃ 이상에서는 약의 성분이 감소함을 발견하여 특수 건조기를 설계 완성하였다. 또한 약용 식물의 취급시 부가되는 오염물은 법제 과정에서 해결 할 수 있었다. 취급과정에서 세균의 오염 역시 섭씨 120℃로 건조하므로서 해결된 것이다. 다음은 약품의 부패에 대하여 염려가 되었다.As such, it was a very difficult task to make all 100 kinds of medicines effective on the human body. However, medicinal plants were first formulated and completely solved by adding dopamine, benincasae pericarpium extract, and hydroxy citric acid. In addition, in order to process the medicinal ingredients more completely, 50 mesh powder was extracted before extraction, and the contact surface with ethyl alcohol was broadened and almost completely extracted. However, ethyl alcohol is a flammable substance and is very dangerous to fire. Accordingly used with 30-60% alcohol. Alcohols that evaporate during the concentration of weak ingredient extracts present a risk of pollution. This is done by recovering alcohol and supplementing the facility in mass production. In particular, the process of drying the concentrate was difficult. Above 120 ° C, the medicinal component was found to be reduced, and a special dryer was designed and completed. In addition, contaminants added during the handling of medicinal plants could be solved during the legal process. Contamination of bacteria during handling was also solved by drying at 120 ° C. The following concerns about the corruption of the drug.

본 발명에서는 보존료를 사용하지 않기 때문이다. 그러나 약성분 중 항균작용 성분이 있기 때문에 농축액을 100% 건조 시키므로서 해결할 수 있었다.This is because no preservative is used in the present invention. However, because there is an antibacterial component of the drug component was able to solve by drying the concentrate 100%.

1) A용기의 약용 식물의 약 성분을 적당히 절편한 홍삼(紅蔘), 대산(大蒜), 고추(capsicum), 의이인(薏苡仁), 곤약(崑蒻), 다시마(Kelp), 녹차(綠茶), 키토산(chitosan)을 각각 30-50부씩 평량하여 취하고 2% 염수(鹽水) 200-400부, 탁주(에틸알콜 6%) 즉 막걸리 100-300부 그리고 우유 30-50부를 가하여 24시간 침전숙성 시킨 후 가하여진 염수, 탁주 그리고 우유를 잘 흔들어 씻은 후 건져 건조시킨다. 건조 후 약재(藥材)를 50메쉬(mesh)로 분쇄한 후 도파민(dopamine) 1-10부와 동과피(Benincasae pericarpium) 추출물 100-300부 그리고 하이드록시시트릭산(Hydroxy citric acid) 300-500부를 가하고 30-60% 에틸알콜(Ethyl alcohol) 500-1,500부를 가하여 용기의 뚜껑을 밀폐시킨다. 15일 후면 수용성 및 유용성 약성분이 거의 다 추출되는 것이다. 이것을 여과하여 400-800부를 취득한다. 취득액을 다시 농축하고 이때 에틸알콜은 인화성이 있으므로 주의를 하여야 한다. 이 취득액을 90-110℃로 3시간 동안 농축하였다. 이 농축된 것을 100-140℃의 건조기에서 5시간 완전 건조시킨 것이다. 이것을 200메쉬 이상 분말로 하여 그 생성물로 한다.1) Red ginseng, Daesan, Capsicum, Ui-in, Konjac, Kelp, Green tea ), Take 30-50 parts of chitosan, and add 200-400 parts of 2% brine, 200-400 parts of Takju (6% ethyl alcohol), that is, 100-300 parts of rice wine, and 30-50 parts of milk. After shaking, shake the added brine, Takju and milk well and dry them. After drying, medicinal herbs are pulverized into 50 mesh, and then 1-10 parts of dopamine, 100-300 parts of Benincasae pericarpium extract, and Hydroxy citric acid 300-500 Part is added and 500-1,500 parts of 30-60% ethyl alcohol are sealed to close the lid of the container. After 15 days, almost all of the water-soluble and oil-soluble drug ingredients are extracted. This is filtered to obtain 400-800 parts. Concentrate the obtained solution again, and care should be taken as ethyl alcohol is flammable. This acquisition was concentrated to 90-110 ° C. for 3 hours. The concentrated product was completely dried in a drier at 100-140 ° C. for 5 hours. This is made into the powder which is 200 mesh or more, and it is set as the product.

2) B용기에 약용식물을 1)에서와 같이 두충(杜沖), 오가피(五加皮), 홍화(紅花), 달맞이꽃(Evening primrose) 또는 월견초(月見草), 육계(肉桂), 구기자(枸杞子), 위유(), 당귀(當歸)를 각각 20-40부씩 평량하여 취하고 2% 염수(鹽水) 100-300부, 탁주(에틸알콜 6%) 즉 막걸리 50-150부 그리고 우유 30-50부를 가하여 24시간 침전 숙성시킨 후 가하여진 염수, 탁주 그리고 우유를 잘 흔들어 씻은 후 건져 건조시킨다. 건조 후 약재(藥材)를 50메쉬(mesh)로 분쇄한 후 도파민(dopamine) 1-10부와 동과피(Benincasae pericarpium) 추출물 100-200부 그리고 하이드록시 시트릭산(Hydroxy citric acid) 200-400부를 가하고 30-60% 에틸알콜(Ethyl alcohol) 500-1,000부를 가하여 용기의 뚜껑을 밀폐시킨다. 15일 후면 수용성 및 유용성 약성분이 거의 다 추출되는 것이다. 이것을 여과하여 200-600부를 취득하였다. 이 여과액을 3시간동안 90-110℃로 농축하였다. 이 농축된 것을 100-140℃의 건조기에서 5시간 건조한 후 200메쉬 이상으로 분쇄하여 그 생성물로 한다.2) Medicinal plants are placed in B container as in 1). Tossop, Ogapi, Safflower, Evening primrose or Evening Primrose, Broiler, Goji 위 子) ), Take 20-40 parts of Angelica gigas, and weigh 100-300 parts of 2% brine, 100-300 parts of Takju (6% ethyl alcohol), 50-150 parts of rice wine, and 30-50 parts of milk. After shaking, shake the added brine, Takju and milk well and dry them. After drying, medicinal herbs are pulverized into 50 mesh, 1-10 parts of dopamine, 100-200 parts of Benincasae pericarpium extract, and 200-400 parts of hydroxy citric acid. Add 500-1,000 parts of 30-60% Ethyl alcohol and close the lid of the container. After 15 days, almost all of the water-soluble and oil-soluble drug ingredients are extracted. This was filtered to obtain 200-600 parts. This filtrate was concentrated to 90-110 ° C. for 3 hours. The concentrated product was dried in a dryer at 100-140 ° C. for 5 hours, and then ground to 200 mesh or more to obtain the product.

3) C 용기에 1)에서와 같이 산수유(山茶萸), 영지(靈芝), 연자육(蓮子肉), 승마(升麻), 하수오(何首烏), 해송자(海松子), 목향(木香)을 각각 10-30부씩 평량하여 취하고 2% 염수(鹽水) 100-300부, 탁주(에틸알콜 6%) 즉 막걸리 50-150부 그리고 우유 10-30부를 가하여 24시간 침전 숙성시킨 후 가하여진 염수, 탁주 그리고 우유를 잘 흔들어 씻은 후 건져 건조 시킨다. 건조 후 여기에 흑두(黑豆) 5-15부, 감초(甘草) 5-15부 그리고 증류수 300-500부를 취하여 약 2시간 서서히 가열한다. (콩이 익을 때까지) 콩이 완전히 익으면 가열을 중지하고 냉각시킨 후 가하여진 흑두와 감초를 제거하고 건져 건조시킨다. 여기에 감초(甘草) 10-30부를 가하여 50메쉬(mesh)정도로 분쇄한 후 도파민(dopamine) 1-10부와 동과피(Benincasae pericarpium) 추출물 50-150부 그리고 하이드록시 시트릭산(Hydroxy citric acid) 100-300부를 가하고 30-60% 에틸알콜(Ethyl alcohol) 300-600부를 가하여 용기의 뚜껑을 밀폐시킨다. 15일 후면 수용성 및 유용성 약성분이 거의 다 추출되는 것이다. 이것을 여과하여 200-300부를 취득하였다. 이 여과액을 3시간 동안 90-110℃로 농축하였다. 이 농축된 것을 100-140℃의 건조기에서 5시간 건조시킨 후 200메쉬 이상으로 분쇄하여 그 생성물로 한다. A용기, B용기, C용기 생성물을 잘 혼합·혼연(渾然)하여 최종 생성물로 한다.3) In the C container, as in 1), hawthorn, ganoderma, yeonjak (연 子 肉), horse riding (하), shouo (,), sea song (자), mokyang (木香) Take 10-30 parts of each weight and add 100-300 parts of 2% brine, Takju (6% ethyl alcohol), 50-150 parts of Makgeolli, and 10-30 parts of milk. Shake well, wash, dry and dry milk. After drying, 5-15 parts of black bean, 5-15 parts of licorice, and 300-500 parts of distilled water are taken and heated slowly for about 2 hours. When the beans are fully cooked, stop heating, cool, remove the black beans and licorice, and dry them. Add 10-30 parts of licorice and grind to 50 mesh, and then 1-10 parts of dopamine, 50-150 parts of Benincasae pericarpium extract, and hydroxy citric acid. Add 100-300 parts and add 300-600 parts of 30-60% Ethyl alcohol to close the lid of the container. After 15 days, almost all of the water-soluble and oil-soluble drug ingredients are extracted. This was filtered to obtain 200-300 parts. This filtrate was concentrated to 90-110 ° C. for 3 hours. The concentrated product was dried in a dryer at 100-140 ° C. for 5 hours, and then ground to 200 mesh or more to obtain the product. The A, B and C container products are mixed and kneaded well to obtain the final product.

[실시에1][Example 1]

1) A용기에 약용 식물의 약성분을 적당히 절편한 홍삼, 대산, 고추, 의이인, 곤약, 다시마, 녹차, 키토산을 각각 400g씩 평량하여 취하고 2%염수 3,000cc, 탁주(에틸알콜 6%) 2,000cc 그리고 우유 400cc를 가하여 24시간 침전숙성 시킨 후가하여진 염수, 탁주 그리고 우유를 잘 흔들어 씻은 후 건져 건조시킨다. 건조 후 여기에 도파민(dopamine) 18g과 동과피(Benincasae pericarpium) 추출물 2,000g 그리고 하이드록시 시트릭산(Hydroxy citric acid) 4,000g을 가하고 50%에틸알콜(Ethyl alcohol) 10,000cc를 가하여 용기의 뚜껑을 밀폐시킨다. 15일후 여과하여 약성분 액기스 6,000cc를 취득하였다. 이 취득액을 100℃로 3시간 농축하였다. 이 농축된 액을 건조기에서 120℃ 상태에서 5시간 완전 건조 시킨 것이다. 이것을 200메쉬 이상으로 분쇄하여 고운 분말 600g을 취득하였다.1) Take 400 g of red ginseng, Daesan, red pepper, Ui-in, konjac, kelp, green tea, and chitosan, each weighing 400 g of 2% saline 3,000cc, Takju (ethyl alcohol 6%) 2,000 cc and milk 400cc is added to precipitate for 24 hours, and then the added brine, takju and milk are well shaken, washed and dried. After drying, 18 g of dopamine, 2,000 g of Benincasae pericarpium extract, and 4,000 g of hydroxy citric acid were added and 10,000 cc of 50% ethyl alcohol was added to seal the lid of the container. Let's do it. Filtration after 15 days to obtain a drug extract 6,000cc. This acquisition liquid was concentrated to 100 degreeC for 3 hours. This concentrated solution was completely dried in a dryer at 120 ° C. for 5 hours. This was pulverized to 200 mesh or more to obtain 600 g of fine powder.

2) B용기에 약용 식물을 1)에서와 같이 두충, 오가피, 홍화, 달맞이꽃씨, 육계, 구기자, 위유, 당귀를 각각 300g씩 평량하여 취하고 2%염수 2,000cc, 탁주(에틸알콜 6%) 1,000cc 그리고 우유 400cc를 가하여 24시간 침전 숙성시킨 후 가하여진 염수, 탁주 그리고 우유를 잘 흔들어 씻은 후 건져 건조 시킨다. 건조 후 여기에 도파민(dopamine) 13g과 동과피(Benincasae pericarpium) 추출물 1,500g 그리고 하이드록시 시트릭산(Hydroxy citric acid) 3,000g을 가하고 50% 에틸알콜(Ethyl alcohol) 8,000cc를 가하여 용기의 뚜껑을 밀폐시킨다.2) Take medicinal plants in B container as in 1), and weigh 300g each of Tobacco, Ogapi, Safflower, Evening Primrose Seed, Broiler, Wolfberry, Stomach Milk, Angelica, 2% Saline 2,000cc, Takju (Ethyl Alcohol 6%) 1,000 cc and milk 400cc is added to precipitate for 24 hours, and then the salt, takju and milk added are shaken well, washed and dried. After drying, 13 g of dopamine, 1,500 g of Benincasae pericarpium extract, and 3,000 g of hydroxy citric acid were added and 8,000 cc of 50% ethyl alcohol was added to seal the lid of the container. Let's do it.

15일 후 여과하여 약성분 액기스 4,300cc를 취득하였다. 이 취득액을 100℃로 3시간 농축하였다. 이 농축된 액을 건조기에서 120℃ 상태로 5시간 완전 건조 시킨 것이다. 이것을 200메쉬 이상으로 분쇄하여 고운 분말 430g을 취득하였다.After 15 days, the resultant was filtered to obtain 4,300 cc of drug extract. This acquisition liquid was concentrated to 100 degreeC for 3 hours. The concentrated solution was completely dried in a dryer at 120 ° C. for 5 hours. This was ground to 200 mesh or more to obtain 430 g of fine powder.

3) C용기에 1)에서와 같이 산수유, 영지, 연자육, 승마, 하수오, 해송자, 목향을 각각 200g씩 평량하여 취하고 2%염수 2,000cc, 탁주(에틸알콜 6%) 1,000cc 그리고 우유 200cc를 가하여 24시간 침전숙성 시킨 후 가하여진 염수, 탁주 그리고우유를 잘 흔들어 씻은 후 건져 건조 시킨다. 건조 후 여기에 흑두(黑豆) 100g, 감초(甘草) 100g 그리고 증류수 4,000cc를 취하여 약 2시간 서서히 가열 한다. (콩이 익을 때까지) 콩이 완전히 익으면 가열을 중지하고 냉각시킨 후 가하여진 흑두와 감초를 제거하고 건져 건조시킨다. 여기에 감초(甘章) 200g을 가하여 50메쉬 정도로 분쇄한 후 도파민(dopamine) 8g과 동과피(Benincasae pericarpium) 추출물 1,000g 그리고 하이드록시 시트릭산(Hydroxy Citric acid) 2,000g을 가하고 50% 에틸알콜(Ethyl alcohol) 6,000cc를 가하여 용기의 뚜껑을 밀폐시킨다. 15일 후 여과하여 약성분 액기스 2,400cc를 취득하였다. 이 취득액을 100℃로 3시간 농축하였다. 이 농축된 액을 건조기에서 120℃ 상태로 5시간 완전 건조 시킨 것이다. 이것을 200메쉬 이상으로 분쇄하여 고운분말 240g을 취득하였다. A, B, C 용기의 취득물을 잘 혼합·혼연(渾然)하여 최종으로 생성물 1,270g을 취득한 것이다.3) Take 200 g of Cornus, Ganoderma lucidum, lotus root, horseback riding, Sewage, Songsong, and Mokyang in the C container in 200g each, add 2,000cc of 2% brine, 1,000cc of Takju (ethyl alcohol 6%) and 200cc of milk. After settling for 24 hours, the added brine, Takju and milk are well shaken, washed and dried. After drying, take 100g of black bean, 100g of licorice, and 4,000cc of distilled water and heat it slowly for about 2 hours. When the beans are fully cooked, stop heating, cool, remove the black beans and licorice, and dry them. To this, 200 g of licorice was added and pulverized to about 50 meshes. Then, 8 g of dopamine, 1,000 g of Benincasae pericarpium extract, and 2,000 g of hydroxy citric acid were added and 50% ethyl alcohol ( Ethyl alcohol) 6,000cc is added to seal the lid of the container. Filtration after 15 days to obtain 2,400cc of drug extract. This acquisition liquid was concentrated to 100 degreeC for 3 hours. The concentrated solution was completely dried in a dryer at 120 ° C. for 5 hours. This was ground to 200 mesh or more to obtain 240 g of fine powder. The obtained materials of A, B, and C containers were mixed and kneaded well, and finally 1,270 g of the product was obtained.

이것을 500mg 캅셀(capsule)에 충진하여 2,540캅셀 약품을 생산한 것이다.It is filled with 500 mg capsules to produce 2,540 capsules.

본 발명의 요약서 에서과 같이 100여 성분의 약효로서 이것을 대별하면 대보원기(大補元氣), 보폐익비(補肺益脾), 보간신(補肝腎), 강근골(强筋骨), 안태(安胎), 거풍습(祛風濕), 활혈거어(活血祛瘀), 윤폐(潤肺), 활장(滑腸), 보신익정(補腎益精), 양간명목(養肝明目), 자음윤폐(滋陰潤肺), 양위생진(養胃生津), 보혈조경(補血調經), 활혈지통(活血止痛), 보익간신(補益肝腎), 양장(養腸), 양심안신(養心安神), 익신고삽(益賢固澁), 청열해독(情熱解毒), 승거양기(昇擧陽氣), 익정혈(益精血), 윤장통변(潤陽通便), 보비윤폐(補脾潤肺), 행기지통(行氣止痛),보중익기(補中益氣), 사화해독(瀉火解毒), 윤폐거담(潤肺祛痰), 완화약성(緩和藥性), 부신피질자극작용(副賢皮質刺載作用), 성기능촉진작용(性機能促進作用), 강심작용(强心作用), 혈당저하작용(血糖低下作用), 항 아나필라시스작용(抗 Anaphylaxis 作用), 항이뇨작용(抗利尿作用), 말초혈관수축·확장작용(末梢血管收縮·擴張作用), 진경작용(鎭痙作用), 혈압강하작용(血壓降下作用), 진정작용(鎭靜作用), 진통작용(鎭痛作用), 강장작용(强壯作用), 혈관확장작용(血管擴張作用), 자양강장작용(滋養强壯作用), 간세포신생촉진작용(肝細胞新生促進作用), 스테로이드 호르몬 유사작용(steroid hormone 類似作用), 통변작용(通便作用), 자궁기능조절작용(子宮機能調節作用), 항진균작용(抗眞菌作用), 사하작용(瀉下作用), 수렴작용(收斂作用), 진해작용(鎭咳作用), 거담작용(祛痰作用), 해열작용(解熱作用), 해독작용(解毒作用), 콜레스테롤저하작용(cholesterol 低下作用), 동맥경화억제작용(動脈硬化抑制作用), 항바이러스작용(抗 virus 作用), 스테로이드호르몬 유사작용(steroid hormone 類似作用), 중추신경흥분작용(中樞神經興奮作用), 항결핵작용(抗結核作用), 육상동맥경화방지작용(粥狀動脈硬化防止作用), 구풍작용(驅風作用), 장연동촉진작용(陽動促進作用), 코르티코이드양작용(Corticoid 樣 作用), 위산분비억제작용(胃酸分泌抑制作用), 항염작용(抗炎作用), 당뇨병(糖尿病), 여성의 생리병(女性의 生理病), 건위작용(健胃作用), 혈액순환촉진작용(血液循環促進作用), 체지방분해작용(體脂肪分解作用), 성인병(成人病)예방 및 비만증(肥滿症) 개선 등을 목표(目標)로 연구개발한 약품이다. 본 발명품은 성인병 예방 및 비만증 개선을 위한 건강식품으로 제품화한다면 그 활용범위는 더욱 더 확대될 것이다.As described in the summary of the present invention as a medicinal effect of about 100 components, Daebowongi (大補 元氣), Bojekwibi (補肺 益脾), interpolation (신), Kang Geungol (强 筋骨), Antae (安胎) ), Giant wind habit, vigor blood, active lung, bowel, bosin ikjeong, binocular nominal consonant ,, Yang Sansengjin (보 生 津), Blood-Blood Landscaping, Live Blood Stem, Boik Ganshin, Yangjang, Conscience Anxin, Ikshin shovel, clear heat detoxification, sensational curiosity, 정 陽 통, Ikjeong blood, yunyangtong stool, bobi yun lung ), Tract cramps, Bojung Ikgi, Sahwa detoxification, yundam geodam, palliative weakness, adrenal cortex stimulation (緩)皮質 刺 載 作用), sexual function promoting action (性 機能 促進 作用), cardiovascular action (强 心 作用), hypoglycemic action (血糖 低下 作用), Anaphylaxis action, antidiuretic action, peripheral vascular contraction and dilation, 경 管 收縮 收縮 擴 作用, jingyeong, blood pressure lowering action (血壓 降下 作用) , Sedation (진 作用), analgesic (鎭 痛 作用), tonic action (强壯 作用), vasodilation (血管 擴張 作用), nourishing tonic action (滋養 强壯 作用), hepatocyte proliferation (작용 新生)促進 作用, steroid hormone-like action, stool act (通便 作用), uterine function regulating action (子宮 機能 調節 作用), antifungal action (抗 眞 菌 作用), lowering action (瀉 下 作用), Astringent (收斂 作用), antitussive action (鎭 咳 作用), expectorant action (해 作用), fever action (解熱 作用), detoxification (解毒 作用), cholesterol lowering (cholesterol 低下 作用), arteriosclerosis suppression Action, antiviral action, steroid hormone-like action似 作用), central nervous system excitement (中樞神經 興奮 作用), anti-tuberculosis (抗結核 作用), terrestrial arteriosclerosis preventive action (粥 狀 動脈硬化 防止 作用), gukdong action (장 風 作用), intestinal synchrony promoting action (陽動 促進 作用, Corticoid effect (Corticoid 作 作用), gastric acid secretion inhibitory effect (염 分 염 制作 用), anti-inflammatory action (抗炎 作用), diabetes, women's menstrual diseases, health The study aims to improve the effects of 健胃 作用, blood circulation, body fat decomposition, prevention of adult diseases and obesity. It is a developed drug. If the present invention is commercialized as a health food for preventing adult diseases and improving obesity, its scope of use will be further expanded.

자체 동물 및 임상 실험 예 (시험용"NANO Diet" 복용자의 말씀)In-house animal and clinical trial examples (as spoken by the "NANO Diet" taker)

1) 실험용 동물(흰쥐) 실험에서 300g이 되는 흰쥐 2마리를 준비하여 각각 1마리씩 격리시켜 실험기구에 넣고 실험을 하였다. 매일 50g씩 평량하여 일반 먹이 사료를 준 대조구의 흰쥐와 본 제품 50mg을 먹이사료에 혼합하여 50g 씩 평량하여 1일 1회씩 30일 동안 먹이 사료를 준 실험용 흰쥐는 약 20g이라는 현저한 체중 감량 효과가 있다는 것이 실험결과로 확인 되었음.1) Experimental animals (rats) In the experiment, two rats, each weighing 300 g, were prepared and isolated one by one. The rats of the control group fed 50g daily and fed the normal diet and the 50mg of this product mixed with the feed diet were weighed 20g once a day by weighing 50g once a day for 30 days. It was confirmed by the experimental results.

2) 55세의 중년 남자분은 어깨와 목이 뻣뻣하다고 하여 본 제품을 1개월간 복용하게 한바 그러한 증상이 개선되어 매우 기쁘다고 함.2) A 55-year-old man who is stiff in his shoulders and neck has been taking this product for a month.

3) 49세의 중년 여성분은 허리와 다리가 너무나 뻐근하다고 하여 본 제품을 1개월간 복용하게 한바 그러한 증상이 없어 졌다고 함.3) A 49-year-old middle-aged woman said that her waist and legs were so clumsy that she had taken this product for a month.

4) 28세된 남자분의 체중이 120kg 이였는데 본 제품을 1개월간 복용한후 18kg의 현저한 체중 감량 효과를 보았다고 매우 기쁘다고 함.4) A 28-year-old man weighed 120kg, but after taking this product for a month, he was very happy to see a significant weight loss effect of 18kg.

5) 25세된 숙녀분의 체중이 110kg 이였는데 그 숙녀분은 굶는 다이어트가 아닌 식사를 하면서 다이어트 효과를 볼수 있는 제품을 찾고 있었던바 당사의 제품인 먹으면서 다이어트 하는 본 제품을 1개월간 복용한 결과 건강을 유지하면서 16kg의 감량 효과를 보았다고 기뻐하면서 좋은 제품이라고 칭찬했음.5) A 25-year-old lady weighed 110kg, and she was looking for a product that would benefit from dieting while not eating a hungry diet. I was delighted to see the weight loss effect and praised it as a good product.

6) 53세의 중년 여성분은 몸의 비만뿐만 아니라 성인병의 여러 증상들이 나타난다고 하여 본 제품을 3개월간 복용하게 한바 현저한 성인병예방 및 비만증 개선효과를 보았다고 함.6) A 53-year-old middle-aged woman had several symptoms of adult illness as well as obesity, and she took 3 months of this product.

7) 견본품 복용자가 100여명이 된바 이대로라도 좋으니 판매하기를 원하였으나 정식제품이 아니기 때문에 판매가 불가능 하였고 그래서 이 약품에 자신감을 갖고 발명특허를 출원하기에 이름.7) The sample takers were about 100 people, so it was okay to sell them, but it was impossible to sell them because it was not a regular product.

Claims (8)

발명의 구성에서와 같이 약용 식물을 법제한 후 도파민(dopamine) 1-10부와 동과피(Benincasae pericarpium) 추출물 50-300부 그리고 하이드록시 시트릭산(Hydroxy citric acid) 100-500부를 첨가하여 에틸알콜(Ethyl alcohol)로 추출한 액기스 즉As in the composition of the invention, ethyl alcohol is added by adding 1-10 parts of dopamine, 50-300 parts of Benincasae pericarpium extract and 100-500 parts of hydroxy citric acid after the preparation of medicinal plants. The extract extracted with (Ethyl alcohol) 1) 진센노사이드로(Ginsenoside Ro), 알에이~알에이치(Ra~Rh), 파낙시놀(panaxynol), β-엘레멘(β-Elemene), β-시토스테롤( β-sitosterol), 아미노산(Amino acids), 펩타이드(peptides), 말톨(Maltol), 콜린(choline), 알릴시스테인설폭사이드(Allylcysteine sulfoxide), 캅사이신(capsaicin), 디히드로-캅사이신(Dihydro-capsaicin), 아이소-운데코일 바닐릴아마이드(Iso-undecoyl vanillylamide), 캅산틴(capsanthin), 카로텐(carotene), 비타민 C(vitamin c), 전분(starch), 지방유(Fatty oil), 코익솔(coixol), 스테롤(sterol), 비타민B1(vitaminB1), 코익센노라이드(coixenolide), D-글루코스(D-Glucose), D-만노스(D-mannose), 라미나리아(Laminaria), 자포니카(Japonica), 인(phosphorus), 요오드(Iodine), β-카로틴(β-carotin), 푸코이단(fucoidan), 라미나린(Laminarin), 만니톨(mannitol), 폴리페놀(polyphenol), 탄닌(Tannin), 카테킨(catechin), 글루코사민(Glucosamin) 등의 액기스 각각 30-50부.1) Ginsenoside Ro, Al-Rh, Panaxynol, β-Elemene, β-Sitosterol, Amino Acid ( Amino acids, peptides, maltol, choline, allylcysteine sulfoxide, capsaicin, dihydro-capsaicin, iso-undecoyl vanylylamide (Iso-undecoyl vanillylamide), capsanthin, carotene, vitamin c, starch, faty oil, coixol, steol, vitamin B 1 (vitaminB 1 ), coixenolide, D-glucose, D-Glucose, D-mannose, Laminaria, Japonica, phosphorus, Iodine , β-carotin, fucoidan, laminarin, mannitol, polyphenol, tannin, catechin, glucosamine, Glucosamin, etc. 30-50 copies each. 2) 구타-페르카(Gutta-percha), 케토스(ketose), 클로로 겐산(chlorogenicacid), 펙틴(pectin), 아칸토사이드 A, B, C, D(Acanthoside A, B, C, D), 다우코스테롤(Daucosterol), 폴리아세틸렌(polyacetylenes), 질리오 덴드린(Ziliodendrin), β-시토스테롤 (β-sitosterol), 캄페스테롤(campesterol), 에톡시-하이드록시-안식향산(Ethoxy-hydroxy-benzoic acid), 카르타민(carthamin), 사플로르 황(黃) (safflor yellow), 카르타미딘(carthamidin), 리그난(Lignan), 리놀산(linoleic acid), 감마-리놀렌산(γ-linolenic acid), 베타인(Betaine), 비타민B1(vitamin B1), 신남 알데하이드(cinnamic aldehyde), 초산 신나밀(cinnamyl acetate), 초산 페닐프로필(phenylpropyl acetate), 제아잔틴(Zeaxanthin), 피살리엔(physalien), 뮤신(Mucin), 데쿠르신(Decursin), 데쿠르시놀(Decursinol), 노다케닌 등의 쿠마린 유도체와 α-피넨(Nodakenin 등의 coumarin 유도체와 α-pinene), 리모넨(Limonene), β-유데스몰(β-Eudesmol), 엘레몰 등을 주로한 정유(Elemol 등을 주로한 精油) 등의 액기스 각각 20-40부.2) Gutta-percha, ketose, chlorogenic acid, pectin, acanthoside A, B, C, D (Acanthoside A, B, C, D), Doucosterol, polyacetylenes, Ziliodendrin, β-sitosterol, campesterol, Ethoxy-hydroxy-benzoic acid ), Carthamin, safflor yellow, carthamidin, lignan, linoleic acid, gamma-linolenic acid, betaine Betaine), vitamin B 1 (vitamin B 1), cinnamaldehyde (cinnamic aldehyde), ethyl cinnamyl (cinnamyl acetate), ethyl-phenylpropyl (phenylpropyl acetate), zeaxanthin (zeaxanthin), killed Lee yen (physalien), mucin (mucin Coumarin derivatives, such as decursin, decursinol, and nodakenin, coumarin derivatives such as nodakenin, α-pinene, limonene, and β- 20-40 parts each of oil extracts such as essential oils mainly including Eudemol and β-Eudesmol. 3) 모로니사이드(Morroniside), 로가닌(Loganin), 코르닌(cornin), 몰식자산(Gallic acid), 주석산(Tartaric acid), 능금산(Malic acid), 지로포르산(Gyrophoric acid), 레카노르산(Lecanoric acid), 넬룸빈(Nelumbine), 조투신(Zotusine), 리엔시닌(Liensinine), 프로누시페린(Pronuciferine), 시미틴(cimitin), 시미시푸긴(cimicifugin), 살리실산(salicylic acid), 지방산(Fatty acid), 크리소파놀(chrysophanol), 에모딘(Emodin), 레인(Rhein), 지방유(Fatty oil), 단백질(protein), 코스투슬락톤(costuslactone),코스트산(costic acid), 코스톨(costol), α-, β-코스텐(α-, β-costen), 사우 수린(saussurine), 이눌린(Inulin), 수지(樹脂), 글라이시리진(Glycyrhizin), 리퀴리타이게닌(Liquiritigenin), 글루코스(Glucose), 만니톨(Mannitol), 능금산(Malic acid), ℓ-아스파라긴(ℓ-Asparagin) 등의 액기스 각각 10-30부를 농축하고 건조·분쇄하여 제조된 성인병 예방 및 비만증 개선제 조성물.3) Morroniside, Loganin, Cornin, Gallic acid, Tartaric acid, Malic acid, Gyrophoric acid, Lecanor Lecanoric acid, Nelumbine, Zotusine, Liensinine, Pronuciferine, cimitin, cimicifugin, salicylic acid ), Fatty acid, Chrysophanol, Emodin, Rhein, Fatty oil, Protein, Costuslactone, Costic acid , Costol, α-, β-costen, α-, β-costen, saussurine, inulin, resin, glycyrhizin, liquiditage Concentrate, dry and pulverize 10-30 parts of each of liquids such as liquidin, glucose, mannitol, malic acid and l-asparagin, and prevent and reduce obesity. Agent composition. 본문 및 청구항 1의 1)에서의 여러 약 성분은 홍삼, 대산, 고추, 의이인, 곤약, 다시마, 녹차, 키토산에서 추출한 약성분임.Various drug components in the body and 1) of claim 1 are drug components extracted from red ginseng, Daesan, red pepper, Uiin, konjac, kelp, green tea, and chitosan. 본문 및 청구항 1의 2)에서의 여러 약 성분은 두충, 오가피, 홍화, 달맞이꽃 또는 월견초, 육계, 구기자, 위유, 당귀에서 추출한 약성분임.Various drug components in the main body and 2) of claim 1 are the drug components extracted from the beetle, agari, safflower, evening primrose or moonflower, broiler, wolfberry, stomach milk, Angelica. 본문 및 청구항 1의 3)에서의 여러 약 성분은 산수유, 영지, 연자육, 승마, 하수오, 해송자, 목향, 감초에서 추출한 약성분임.Various drug components in the main body and 3) of claim 1 are medicinal components extracted from cornus, ganoderma lucidum, lotus root, horseback riding, sewage, raptor, mokyang, licorice. 본문 및 청구항 1에서의 법제로 사용된 약품은 감초, 흑두(검은콩), 탁주, 우유(액)와 2% 염수임.The drugs used in the text and the legislation in claim 1 are licorice, black bean (black beans), takju, milk (liquid) and 2% saline. 본문 및 청구항 1에서 사용된 도파민은 학술명으로 도파민(dopamine) 또는 3-하이드록시 타이라민 하이드로 클로라이드(3-Hydroxytyramine Hydrochloride) 라는 약품임.Dopamine used in the text and claim 1 in the scientific name is a drug called dopamine or 3-hydroxy tyramine hydrochloride (3-Hydroxytyramine Hydrochloride). 본문 및 청구항 1에서 사용된 것은 동과피(Benincasae Pericarpium)라는 식물에서 추출한 약 성분임.As used in the text and claim 1 is a drug component extracted from a plant called Benincasae Pericarpium. 본문 및 청구항 1에서 사용된 것은 하이드록시 시트릭산 (Hydroxy Citric acid) 이라는 약품임.As used in the text and claim 1 is a drug called hydroxy citric acid.
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