KR20030089160A - Compositions of cosmetics for acned skin containing Ulmus davidiana extracts - Google Patents
Compositions of cosmetics for acned skin containing Ulmus davidiana extracts Download PDFInfo
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- KR20030089160A KR20030089160A KR1020020027231A KR20020027231A KR20030089160A KR 20030089160 A KR20030089160 A KR 20030089160A KR 1020020027231 A KR1020020027231 A KR 1020020027231A KR 20020027231 A KR20020027231 A KR 20020027231A KR 20030089160 A KR20030089160 A KR 20030089160A
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- oil
- cosmetic composition
- skin
- acne
- root extract
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- 239000002537 cosmetic Substances 0.000 title claims abstract description 37
- 239000000203 mixture Substances 0.000 title claims abstract description 32
- 239000000284 extract Substances 0.000 title claims abstract description 26
- 241000949731 Ulmus davidiana Species 0.000 title abstract description 4
- 208000002874 Acne Vulgaris Diseases 0.000 claims abstract description 32
- 206010000496 acne Diseases 0.000 claims abstract description 32
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 7
- 239000004094 surface-active agent Substances 0.000 claims abstract description 6
- 239000000796 flavoring agent Substances 0.000 claims abstract description 4
- 235000013355 food flavoring agent Nutrition 0.000 claims abstract description 4
- 239000008213 purified water Substances 0.000 claims abstract description 4
- 239000003906 humectant Substances 0.000 claims abstract description 3
- 239000003921 oil Substances 0.000 claims description 14
- 235000019198 oils Nutrition 0.000 claims description 14
- 239000000341 volatile oil Substances 0.000 claims description 12
- 239000000171 lavandula angustifolia l. flower oil Substances 0.000 claims description 9
- 239000004480 active ingredient Substances 0.000 claims description 8
- 241000721662 Juniperus Species 0.000 claims description 7
- 235000019501 Lemon oil Nutrition 0.000 claims description 6
- 239000006071 cream Substances 0.000 claims description 6
- 239000010501 lemon oil Substances 0.000 claims description 6
- 239000001525 mentha piperita l. herb oil Substances 0.000 claims description 6
- 235000019477 peppermint oil Nutrition 0.000 claims description 6
- 239000010668 rosemary oil Substances 0.000 claims description 6
- 229940058206 rosemary oil Drugs 0.000 claims description 6
- 239000010677 tea tree oil Substances 0.000 claims description 6
- 229940111630 tea tree oil Drugs 0.000 claims description 6
- 238000009472 formulation Methods 0.000 claims description 5
- 239000006210 lotion Substances 0.000 claims description 5
- 239000004034 viscosity adjusting agent Substances 0.000 claims description 4
- -1 foundation Substances 0.000 claims description 3
- 239000008267 milk Substances 0.000 claims description 3
- 239000000344 soap Substances 0.000 claims description 3
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- 235000013336 milk Nutrition 0.000 claims description 2
- 230000001815 facial effect Effects 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 8
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 244000000010 microbial pathogen Species 0.000 abstract 1
- 208000017520 skin disease Diseases 0.000 abstract 1
- 210000003491 skin Anatomy 0.000 description 23
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 9
- 230000000845 anti-microbial effect Effects 0.000 description 9
- 238000002360 preparation method Methods 0.000 description 7
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 6
- 241000196324 Embryophyta Species 0.000 description 5
- 239000000419 plant extract Substances 0.000 description 5
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 4
- 241000304886 Bacilli Species 0.000 description 4
- ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 description 4
- 241001106462 Ulmus Species 0.000 description 4
- 238000000605 extraction Methods 0.000 description 4
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- 239000004342 Benzoyl peroxide Substances 0.000 description 3
- OMPJBNCRMGITSC-UHFFFAOYSA-N Benzoylperoxide Chemical compound C=1C=CC=CC=1C(=O)OOC(=O)C1=CC=CC=C1 OMPJBNCRMGITSC-UHFFFAOYSA-N 0.000 description 3
- 244000246386 Mentha pulegium Species 0.000 description 3
- 235000016257 Mentha pulegium Nutrition 0.000 description 3
- 235000004357 Mentha x piperita Nutrition 0.000 description 3
- SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 description 3
- 239000003242 anti bacterial agent Substances 0.000 description 3
- 230000000844 anti-bacterial effect Effects 0.000 description 3
- 235000019400 benzoyl peroxide Nutrition 0.000 description 3
- 229940088597 hormone Drugs 0.000 description 3
- 239000005556 hormone Substances 0.000 description 3
- 235000001050 hortel pimenta Nutrition 0.000 description 3
- 238000011084 recovery Methods 0.000 description 3
- 229930002330 retinoic acid Natural products 0.000 description 3
- 230000028327 secretion Effects 0.000 description 3
- 229930101283 tetracycline Natural products 0.000 description 3
- 229960001727 tretinoin Drugs 0.000 description 3
- 241000894006 Bacteria Species 0.000 description 2
- 240000007311 Commiphora myrrha Species 0.000 description 2
- 235000006965 Commiphora myrrha Nutrition 0.000 description 2
- 239000004909 Moisturizer Substances 0.000 description 2
- 235000007265 Myrrhis odorata Nutrition 0.000 description 2
- 241000191940 Staphylococcus Species 0.000 description 2
- 239000004098 Tetracycline Substances 0.000 description 2
- 150000004347 all-trans-retinol derivatives Chemical class 0.000 description 2
- 230000002280 anti-androgenic effect Effects 0.000 description 2
- 239000000051 antiandrogen Substances 0.000 description 2
- 229940030495 antiandrogen sex hormone and modulator of the genital system Drugs 0.000 description 2
- 229940088710 antibiotic agent Drugs 0.000 description 2
- 125000003118 aryl group Chemical group 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 230000018109 developmental process Effects 0.000 description 2
- 230000002910 effect on acne Effects 0.000 description 2
- 229960003276 erythromycin Drugs 0.000 description 2
- 239000003205 fragrance Substances 0.000 description 2
- 230000007774 longterm Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000001333 moisturizer Effects 0.000 description 2
- 239000002798 polar solvent Substances 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- GHMLBKRAJCXXBS-UHFFFAOYSA-N resorcinol Chemical compound OC1=CC=CC(O)=C1 GHMLBKRAJCXXBS-UHFFFAOYSA-N 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 229960002180 tetracycline Drugs 0.000 description 2
- 235000019364 tetracycline Nutrition 0.000 description 2
- 150000003522 tetracyclines Chemical class 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- 239000001993 wax Substances 0.000 description 2
- NWXMGUDVXFXRIG-WESIUVDSSA-N (4s,4as,5as,6s,12ar)-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide Chemical compound C1=CC=C2[C@](O)(C)[C@H]3C[C@H]4[C@H](N(C)C)C(=O)C(C(N)=O)=C(O)[C@@]4(O)C(=O)C3=C(O)C2=C1O NWXMGUDVXFXRIG-WESIUVDSSA-N 0.000 description 1
- DSSYKIVIOFKYAU-XCBNKYQSSA-N (R)-camphor Chemical compound C1C[C@@]2(C)C(=O)C[C@@H]1C2(C)C DSSYKIVIOFKYAU-XCBNKYQSSA-N 0.000 description 1
- 235000007173 Abies balsamea Nutrition 0.000 description 1
- 229920001817 Agar Polymers 0.000 description 1
- 201000004384 Alopecia Diseases 0.000 description 1
- 239000004857 Balsam Substances 0.000 description 1
- 235000018185 Betula X alpestris Nutrition 0.000 description 1
- 235000018212 Betula X uliginosa Nutrition 0.000 description 1
- 241000723346 Cinnamomum camphora Species 0.000 description 1
- 235000005979 Citrus limon Nutrition 0.000 description 1
- 244000131522 Citrus pyriformis Species 0.000 description 1
- 208000001840 Dandruff Diseases 0.000 description 1
- 206010012442 Dermatitis contact Diseases 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 208000004232 Enteritis Diseases 0.000 description 1
- 208000010201 Exanthema Diseases 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 244000018716 Impatiens biflora Species 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 244000178870 Lavandula angustifolia Species 0.000 description 1
- 235000010663 Lavandula angustifolia Nutrition 0.000 description 1
- 206010034133 Pathogen resistance Diseases 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 244000178231 Rosmarinus officinalis Species 0.000 description 1
- 206010040880 Skin irritation Diseases 0.000 description 1
- 206010041349 Somnolence Diseases 0.000 description 1
- 241000295644 Staphylococcaceae Species 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 239000008272 agar Substances 0.000 description 1
- 238000002814 agar dilution Methods 0.000 description 1
- 208000030961 allergic reaction Diseases 0.000 description 1
- 229940121363 anti-inflammatory agent Drugs 0.000 description 1
- 239000002260 anti-inflammatory agent Substances 0.000 description 1
- 230000002421 anti-septic effect Effects 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 229960000846 camphor Drugs 0.000 description 1
- 229930008380 camphor Natural products 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 239000000306 component Substances 0.000 description 1
- 238000013329 compounding Methods 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 208000010247 contact dermatitis Diseases 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 239000006184 cosolvent Substances 0.000 description 1
- 235000021438 curry Nutrition 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 201000005884 exanthem Diseases 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- 230000009422 growth inhibiting effect Effects 0.000 description 1
- 230000009036 growth inhibition Effects 0.000 description 1
- 208000024963 hair loss Diseases 0.000 description 1
- 230000003676 hair loss Effects 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 230000003780 keratinization Effects 0.000 description 1
- 239000001102 lavandula vera Substances 0.000 description 1
- 235000018219 lavender Nutrition 0.000 description 1
- 229940083980 lavender extract Drugs 0.000 description 1
- 235000020723 lavender extract Nutrition 0.000 description 1
- 230000002366 lipolytic effect Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 208000017983 photosensitivity disease Diseases 0.000 description 1
- 231100000434 photosensitization Toxicity 0.000 description 1
- 238000009160 phytotherapy Methods 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 230000003449 preventive effect Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 206010037844 rash Diseases 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- 230000036556 skin irritation Effects 0.000 description 1
- 231100000475 skin irritation Toxicity 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 208000018556 stomach disease Diseases 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 239000011593 sulfur Substances 0.000 description 1
- 235000001508 sulfur Nutrition 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
- B41J—TYPEWRITERS; SELECTIVE PRINTING MECHANISMS, i.e. MECHANISMS PRINTING OTHERWISE THAN FROM A FORME; CORRECTION OF TYPOGRAPHICAL ERRORS
- B41J2/00—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed
- B41J2/005—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed characterised by bringing liquid or particles selectively into contact with a printing material
- B41J2/01—Ink jet
- B41J2/17—Ink jet characterised by ink handling
- B41J2/20—Ink jet characterised by ink handling for preventing or detecting contamination of compounds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
- B41J—TYPEWRITERS; SELECTIVE PRINTING MECHANISMS, i.e. MECHANISMS PRINTING OTHERWISE THAN FROM A FORME; CORRECTION OF TYPOGRAPHICAL ERRORS
- B41J11/00—Devices or arrangements of selective printing mechanisms, e.g. ink-jet printers or thermal printers, for supporting or handling copy material in sheet or web form
- B41J11/02—Platens
- B41J11/14—Platen-shift mechanisms; Driving gear therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
- B41J—TYPEWRITERS; SELECTIVE PRINTING MECHANISMS, i.e. MECHANISMS PRINTING OTHERWISE THAN FROM A FORME; CORRECTION OF TYPOGRAPHICAL ERRORS
- B41J2/00—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed
- B41J2/005—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed characterised by bringing liquid or particles selectively into contact with a printing material
- B41J2/01—Ink jet
- B41J2/135—Nozzles
- B41J2/165—Prevention or detection of nozzle clogging, e.g. cleaning, capping or moistening for nozzles
- B41J2/16517—Cleaning of print head nozzles
- B41J2/1652—Cleaning of print head nozzles by driving a fluid through the nozzles to the outside thereof, e.g. by applying pressure to the inside or vacuum at the outside of the print head
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
- B41J—TYPEWRITERS; SELECTIVE PRINTING MECHANISMS, i.e. MECHANISMS PRINTING OTHERWISE THAN FROM A FORME; CORRECTION OF TYPOGRAPHICAL ERRORS
- B41J2/00—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed
- B41J2/005—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed characterised by bringing liquid or particles selectively into contact with a printing material
- B41J2/01—Ink jet
- B41J2/17—Ink jet characterised by ink handling
- B41J2/175—Ink supply systems ; Circuit parts therefor
- B41J2/17503—Ink cartridges
- B41J2/17533—Storage or packaging of ink cartridges
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
- B41J—TYPEWRITERS; SELECTIVE PRINTING MECHANISMS, i.e. MECHANISMS PRINTING OTHERWISE THAN FROM A FORME; CORRECTION OF TYPOGRAPHICAL ERRORS
- B41J29/00—Details of, or accessories for, typewriters or selective printing mechanisms not otherwise provided for
- B41J29/38—Drives, motors, controls or automatic cut-off devices for the entire printing mechanism
Landscapes
- Cosmetics (AREA)
Abstract
Description
본 발명은 정제수, 보습제, 계면활성제, 점도조절제, 오일 및 왁스, 각종 미용 활성성분, 유용성 활성성분, 착향제 등으로 구성된 종래의 화장료 조성물에 있어서, 항균성 활성성분으로서 유근피(楡根皮)추출물을 필수 함유 성분으로 하고, 여기에 공지의 라벤더 오일 (Lavender Oil), 로즈마리 오일 (Rosemary Oil), 티트리 오일 (Tea Tree Oil), 페퍼민트 오일(Peppermint Oil), 레몬 오일(Lemon Oil), 쥬니퍼 오일 (Juniper Oil) 등의 아로마 정유 (Aroma essential oil) 중에서 1종 이상을 더 배합한 것으로서 여드름 유발균인 백색 포도구균 및 여드름 병산간균의 생육을 억제할 뿐만 아니라 과도한 피지분비를 조절함으로써 여드름 피부에 유효한 효과를 갖는 것을 특징으로 하는 유근피추출물을 함유하는 여드름 피부용 화장료 조성물에 관한 것이다.The present invention is a conventional cosmetic composition composed of purified water, moisturizers, surfactants, viscosity modifiers, oils and waxes, various cosmetic active ingredients, oil-soluble active ingredients, flavoring agents, etc. It contains essential ingredients such as lavender oil, rosemary oil, tea tree oil, peppermint oil, lemon oil, juniper oil (known as lavender oil). A blend of one or more of Aroma essential oils, such as Juniper Oil, which not only inhibits the growth of acne-causing white staphylococcus and acne bacilli, but also regulates excessive sebum secretion and is effective for acne skin. It relates to a cosmetic composition for acne skin containing a root-derived extract, characterized in that it has a.
일반적으로, 여드름은 피지분비 과잉, 피부각질화 과잉 및 혐기성 피부상에 존재하는 균인 백색 포도구균과 여드름 병산간균에 의한 염증 진전에 그 원인이 있는 것으로 알려져 있다. 이러한 여드름을 치료하기 위해 피지 생성을 억제하는 항안드로겐제, 항염제로 작용하는 비스테로이드 소염제, 그리고 항균효과가 있는 레조시놀, 유황 및 벤조일 퍼록사이드(Benzoyl peroxide)와 항생효과가 있는 테트라싸이클린(Tetracyclin), 에리스로마이신 및 매크로싸이클린 등에 의한 여드름 병산간균 등에 대한 활성 억제 방법 등이 있다. 최근에는 레티노익산(Retinoic acid) 등의 비타민A 유도체를 이용한 치료 방법도 많이 사용되고 있다. 또한 오래 전부터 동양에서 약재로 사용되어 오던 몰약 등을 이용한 여드름에 유요한 화장료에 관한 기술도 소개된 바, 대한민국 특허공보 제95-8762호(이형재 등)에 소개되어 있다.In general, acne is known to be responsible for the development of inflammation caused by excess sebum secretion, excess keratinization and anaerobic skin, Staphylococcus aureus and acne bacilli. Anti-androgens that inhibit sebum production, non-steroidal anti-inflammatory drugs that act as anti-inflammatory agents, and antiseptic resorcinol, sulfur and benzoyl peroxide, and tetracycline, which have antibiotics , Erythromycin, macrocycline and the like for acne bacilli bactericidal activity. Recently, many therapeutic methods using vitamin A derivatives such as retinoic acid have been used. In addition, a technology related to cosmetics useful for acne using myrrh, which has been used as a medicinal herb for a long time, has been introduced, and is also disclosed in Korean Patent Publication No. 95-8762 (Lee, Jae Hyung).
이러한 방법들은 여드름 예방과 치료에 있어 어느 정도 성과를 거두고 있으나, 효과적인 측면이나 피부안전성 측면에 있어서 아직 몇 가지 문제점을 가지고 있다. 즉, 호르몬제의 사용은 표피의 성장억제나 기타 호르몬 남용 등의 역효과를 유발할 수 있다고 보고되고 있으며, 레티노익산과 벤조일 퍼록사이드 등은 피부의 자극성과 접촉성 피부염의 우려가, 테트라사이클린을 위시한 항생물질은 내균성의 발생과 광과민 작용의 가능성이 있다고 알려져 있다. 또한 몰약 등 종래의 동양 약재 식물 추출물을 이용한 여드름에 유효한 화장료 조성물은 그 효능에 있어서 유효한 효과는 인정하나 민감성의 여드름 피부에 대해서는 경우에 따라 아레르기 과민반응을 보이는 경우도 있어 그 사용 범위가 다소 한정될 수 있는 문제점을 가지고있다.While these methods have some results in acne prevention and treatment, there are still some problems in terms of effectiveness and skin safety. In other words, the use of hormones has been reported to cause adverse effects such as growth inhibition of the epidermis and other hormone abuse. Retinoic acid and benzoyl peroxide, such as antibiotics including tetracycline, may cause skin irritation and contact dermatitis. The substance is known to have the potential for bacterial resistance and photosensitization. In addition, cosmetic compositions that are effective against acne using conventional oriental herbal plant extracts, such as myrrh, may be effective in their efficacy, but may show an allergic reaction to sensitive acne skin in some cases. I have a problem that could be
본 발명은 이러한 상기 문제점을 고려하여 안출한 것으로 여드름의 원인으로 알려져 있는 여드름 병산간균 및 백색 포도구균에 대해 특이적인 항균작용을 가지고 있으면서도 장기간 사용해도 인체 안전성이 높은 물질을 개발하기 위해 연구를 거듭한 결과, 식물의학(Phytotherapy)에서 사용되고 있는 몇 가지 항균성 식물추출물이 여드름에 대해 유효한 효과를 가지고 있는 것을 알게 되었다. 그리하여 이들 식물추출물을 종래의 화장료 조성물에 함유함으로써 여드름 피부에 유효한 효과를 갖는 화장료 조성물을 개발하게 된 바, 이를 본 발명의 실시예와 함께 상세히 설명하면 다음과 같다.The present invention has been made in view of the above problems and has been studied to develop a material that has a high level of human safety even for long-term use while having a specific antibacterial activity against acne bacilli and white staphylococcus known to be the cause of acne. As a result, several antimicrobial plant extracts used in Phytotherapy have been found to have an effective effect on acne. Thus, by containing these plant extracts in the conventional cosmetic composition bar to develop a cosmetic composition having an effective effect on acne skin, which will be described in detail with an embodiment of the present invention as follows.
본 발명은 정제수, 보습제, 계면활성제, 점도조절제, 오일 및 왁스, 수용성 활성성분, 유용성 활성성분, 착향제 등으로 구성된 종래의 화장료 조성물에 있어서, 항균성 활성성분으로서 여드름 유발균인 여드름 병산간균과 백색 포도구균에 대해 강력한 항균 효과를 가지면서도 과도한 피지분비를 조절하고 장기간 사용시 피부 안전성이 높은 유근피추출물을 필수 함유 성분으로 하고, 여기에 공지의 라벤더 오일, 로즈마리 오일, 티트리 오일, 페퍼민트 오일, 레몬 오일, 쥬니퍼 오일 등의 아로마 정유(Aroma essential oil) 중에서 1종 이상을 화장료 제형과 기능성에 따라 일정량 함유하는 것으로 구성된 것이다.The present invention is a conventional cosmetic composition composed of purified water, humectant, surfactant, viscosity modifier, oil and wax, water soluble active ingredient, oil soluble active ingredient, flavoring agent, etc. It has a strong antibacterial effect against staphylococci but also regulates excessive sebum secretion and contains essential extracts with high skin safety for long-term use.These are known lavender oil, rosemary oil, tea tree oil, peppermint oil and lemon oil. , Aroma essential oil (Juniper oil), such as essential oils (Aroma essential oil) is composed of containing a certain amount depending on the cosmetic formulation and functionality.
본 발명에서 사용되는 유근피추출물과 아로마 에센셜 오일류의 피부에 미치는 작용에 대해 알려진 사실을 기초로 간략히 설명하면 다음과 같다.Briefly described on the basis of the known facts on the skin of the root extract and aromatic essential oils used in the present invention.
유근피는 일명 느릅나무의 뿌리껍질을 말하며, 느릅나무줄기의 껍질은 유백피(楡白皮)라고 하여 구분된다. 학명은 Ulmus davidiana이다. 대한민국의 중부와 북부지방의 산골짜기나 물가에 흔히 자라며, 이른 봄이나 가을에 뿌리껍질을 벗겨서 약으로 쓰여왔다. 동의보감에서는 느릅나무가 성질이 평하고 맛이 달며 독이 없어 부드러워 대소변을 잘 통하게 하고 장, 위의 사열을 없애 장염에 효과적이며, 부은각종 종창과 비위 질환에 효과적이면서도 중독성이 없어 장복해도 무방한 것으로 기록되어 있다.The roots of the roots of the roots of the elm tree is known as the elm tree, and the bark of the elm tree is divided into the milky skin (피 白皮). The scientific name is Ulmus davidiana. It often grows in valleys or watersides in the central and northern regions of Korea, and has been used as a medicinal peeling of its roots in early spring or autumn. In Dongbobom, elm tree has flat nature, taste, and no poison, so it is soft to penetrate urine, and it is effective for enteritis by eliminating intestinal and stomach fever, and it is effective for swollen swelling and stomach disease, and it is not addictive. It is.
라벤더 오일(Lavender oil)는 프랑스 남부로부터 이탈리아에 걸쳐 볼 수 있는 지중해 연안 원산의 자소와 식물인 라벤더의 꽃과 잎에서 추출된다. 가장 대중적인 에센셜 오일이며 효능면에서도 가장 광범위하며 유럽 전통의 방향치료에 있어서 외용, 내용의 쌍방에 있어서 구분된 효능을 인정받고 있다. 로즈마리 오일(Rosemary Oil)는 프랑스 남부와 이탈리아, 스페인 등에 생육하는 자소과 식물인 로즈마리의 잎에서 추출된다. 상쾌한 향기가 기분 좋은 대단히 대중적인 오일로서 창상 회복 작용, 화상 회복 작용, 설사 멈춤 작용, 비듬억제, 탈모개선 등을 주목적으로 사용되고 있다. 또한 티트리 오일(Tea Tree Oil)은 주산지인 호주 등지에서 생육하는 차나무(Tea Tree)의 잎에서 추출된다. 따뜻하고 싱싱한 장뇌 향취를 내며 살균, 소독 작용이 강하고 약간의 진통작용이 있어 상처나 질병의 통증 완화에 사용된다. 페퍼민트 오일(Peppermint Oil)은 일명 박하라고 부르는 것으로서 유럽과 북아메리카 등지에서 생육하는 박하나무 잎에서 추출된다. 산듯하고 시원한 박하 향취를 내며 피로회복, 졸음방지, 냉각효과, 통증 완화작용에 사용된다. 레몬 오일(Lemon Oil)은 미국이나 아르헨티나 등지에서 생육하는 레몬의 껍질을 냉각압착하여 얻으며, 신선하고 달콤한 과일 향취를 내고 살균, 미백 작용이 있다. 마지막으로 쥬니퍼 오일(Juniper Oil)은 유럽, 북아시아, 북아프리카, 북아메리카 등지에서 생육하는 두송나무의 열매에서 추출된다. 신선한 발삼의 나무 향취(woody note)를 내며, 해독작용이 있고 각질제거, 지방분해 및 수렴작용이 있는 것으로 알려져 있다.Lavender oil is derived from the flowers and leaves of lavender, a plant and plant native to the Mediterranean, which can be found throughout southern France and Italy. It is the most popular essential oil, the most extensive in terms of efficacy, and is recognized for its efficacy in both external and internal aspects in the fragrance therapy of European tradition. Rosemary oil is derived from the leaves of rosemary, a locust plant growing in southern France, Italy and Spain. It is a very popular oil with a pleasant scent and is mainly used for wound recovery, burn recovery, diarrhea stopping, dandruff suppression, and hair loss improvement. Tea Tree Oil is also extracted from the leaves of Tea Tree, which grows in Australia. It has a warm and fresh camphor scent and has a strong sterilization and disinfection effect. Peppermint Oil, also known as peppermint, is extracted from the leaves of peppermint growing in Europe and North America. It gives a fresh and cool peppermint scent and is used for fatigue recovery, drowsiness prevention, cooling effect and pain relief. Lemon Oil is obtained by cold pressing the skin of lemons grown in the United States or Argentina. Finally, Juniper Oil is derived from the fruits of the birch tree growing in Europe, North Asia, North Africa, and North America. It has a woody note of fresh balsam, which is known to be detoxifying, exfoliating, lipolytic and astringent.
본 발명에 사용되는 항균성 활성성분인 유근피추출물을 제조하기 위해 사용되는 추출 용매는 메탄올, 에탄올, 아세톤 등의 극성 용매로서, 추출 방법으로 종래의 일반적인 방법으로 이용이 가능한데 , 예를 들면 건조된 유근피에 5~10배 량의 메탄올, 에탄올 혹은 아세톤 등의 극성 용매를 가하여 1~7일간 실온에서 침적 추출하거나 1~5시간 가온 추출하여 식물 추출물을 얻는다. 또한 본 발명에 사용되는 식물인 유근피는 종래의 동결건조 방법으로 건조시키고 미세분말화한 후 추출한다.Extraction solvent used to prepare the root extract of the antimicrobial active ingredient used in the present invention is a polar solvent such as methanol, ethanol, acetone, etc., can be used in the conventional method as an extraction method, for example, dried root skin 5-10 times the amount of methanol, ethanol or acetone and polar solvent is added to immersion extraction at room temperature for 1-7 days or warm extraction for 1-5 hours to obtain a plant extract. In addition, the roots of the plant used in the present invention is extracted by drying and micropowdering by conventional lyophilization method.
본 발명에 있어서 여드름 피부용 화장료 조성물을 피부에 바르는 외용제의 형태로 하는 경우, 피부 외용제 중의 유근피추출물의 배합량은 전체의 0.05~10.0중량%, 특히 0.5~5.0 중량%로 하는 것이 좋고, 여기에 공지의 라벤더 오일(Lavender Oil), 로즈마리 오일(Rosemary Oil), 티트리 오일 (Tea Tree Oil), 페퍼민트 오일(Peppermint Oil), 레몬 오일(Lemon Oil), 쥬니퍼 오일(Juniper Oil) 등의 아로마 정유(Aroma essential oil)중에서 1종 이상을 화장료 제형과 기능성에 따라 적절량 함유할 수 있다.In the present invention, when the cosmetic composition for acne skin is used in the form of an external preparation applied to the skin, the compounding quantity of the root extract in the external preparation for skin is preferably 0.05 to 10.0% by weight, particularly 0.5 to 5.0% by weight, and known here. Aroma essentials such as lavender oil, rosemary oil, tea tree oil, peppermint oil, lemon oil, juniper oil, etc. One or more of the oils may be contained in an appropriate amount depending on the cosmetic formulation and functionality.
본 발명의 화장료 조성물은 상기(上記)한 유근피추출물과 아로마 에센셜 오일들 이외에도 필요에 따라 본 발명의 효과를 저하시키지 않는 범위내에서 피부 외용제에 일반적으로 사용하는 각종 성분, 예를 들면 수용성 성분, 분말 성분, 유분,계면활성제, 보습제, 점도조절제, 방부제, 산화방지제, 향료, 색소 등을 배합하는 것이 가능하다. 또한 종래의 여드름 치료제에 많이 사용되어온 벤조일 퍼록사이드(Benzoyl peroxide)나 테트라싸이클린(Tetracyclin), 에리스로마이신 등의 항균제나 항안드로겐, 스테로이드 등의 호르몬, 레티노익산(Retinoic acid) 등의 비타민A 유도체와 병용이 가능하다.The cosmetic composition of the present invention, in addition to the above-mentioned roots root extract and aroma essential oils, various components generally used for external preparations for skin, for example, water-soluble components and powder, in a range that does not lower the effect of the present invention as necessary. It is possible to blend components, oils, surfactants, moisturizers, viscosity modifiers, preservatives, antioxidants, fragrances, colorants and the like. In addition, it can be used in combination with antibacterial agents such as benzoyl peroxide, Tetracyclin and erythromycin, hormones such as anti-androgens and steroids and vitamin A derivatives such as retinoic acid, which have been widely used in conventional acne treatments. It is possible.
본 발명의 화장료 조성물의 제형은 임의로 선택할 수 있으되,종래의 화장료 제형인 크림, 밀크로션, 유연화장수, 팩, 파운데이션 등 뿐만 아니라, 비누, 세안폼과 같은 세안료 등 여러 가지 형태로 제조할 수 있다.The formulation of the cosmetic composition of the present invention may be arbitrarily selected, but may be prepared in various forms such as face creams such as soap, face wash foam, as well as creams, milk lotions, soft cosmetics, packs, foundations, and the like, which are conventional cosmetic formulations. .
또한 본 발명에 사용되는 식물들은 오래 전부터 동양에서는 민간 요법 또는 한방에서 사용해 오던 재료로서 피부 외용제로 사용시 인체에 대한 안전성이 확인되어 있어서,피부 및 점막에 대한 자극은 거의 없는 것으로 알려져 있다. 본 발명의 유근피추출물 제조 실시예를 구체적으로 나타내면 다음과 같다.In addition, the plants used in the present invention have been used for folk remedies or herbal medicine in the East for a long time, and when used as an external preparation for skin, the safety of the human body has been confirmed, and it is known that there is little irritation to the skin and mucous membranes. Detailed description of the preparation example of the root extract of the present invention is as follows.
〈실시예 1〉: 유근피추출물의 제조<Example 1>: Preparation of root extract
유근피 건조 생약재를 분쇄한것 50g에 메탄올 500㎖를 가하여 실온에서 10일간 침적하여 추출 여과한 후, 그 여과액을 감압 증발하여 1.0g의 농축물을 얻었다.500 g of methanol was added to 50 g of the dried medicinal herb extract, immersed and filtered for 10 days at room temperature. The filtrate was evaporated under reduced pressure to obtain 1.0 g of concentrate.
〈시험예〉: 본 발명의 유근피추출물의 여드름균에 대한 항균 활성 측정<Test Example>: Determination of the antimicrobial activity against acne bacteria of the root extract of the present invention
본 발명에 의한 화장료 조성물의 여드름 발생 예방 효과를 평가해 보기 전에 본 발명에서 사용되는 항균성 유근피추출물 및 상기의 각종 식물성 에센셜 오일의 항균 활성을 한천 희석법에 의해 측정하였다. 즉, 상기 방법에 의해 제조된 유근피추출물과 공지의 상기 에센셜 오일류를 시료로 하여 가열 멸균한 브레인 허트 인퓨전 한천 배지(BHI Agar)에 각종 농도로 희석한 다음, 샤레에 붓고 굳힌 후, 시험균을 도입하여 섭씨 37도에서 혐기 상태로 배양하였다. 48~72 시간 배양한 후, 생육상태를 관찰하여 균이 생육하지 않는 최소 농도를 최소저지농도 (Minimum Inhibitory Concentration ; MIC)로 하여 각 시료의 항균력을 비교하여 표1과 같은 결과를 얻었다.Before evaluating the preventive effect of the acne development of the cosmetic composition according to the present invention, the antimicrobial activity of the antimicrobial root extract and the various vegetable essential oils used in the present invention were measured by agar dilution. That is, dilution to various concentrations in the heat-sterilized Brain Hert Infusion Agar Medium (BHI Agar) using the root extract and the well-known essential oils prepared by the above method as a sample, poured into a curry and hardened, and then introduced test bacteria Cultured in anaerobic condition at 37 degrees Celsius. After incubation for 48 to 72 hours, the growth condition was observed to compare the antimicrobial activity of each sample with the minimum concentration (MIC) as the minimum concentration without bacterial growth.
이상의 결과에서 보는 바와 같이, 특히 유근피추출물이 다른 식물추출물에 비교하여 우수한 항균 효과를 나타내고 있으며, 또한 여기에 라벤더 오일, 로즈마리 오일, 티트리 오일, 페퍼민트 오일, 레몬 오일, 쥬니퍼 오일 중 1종 이상을 함께 혼용하는 경우, 우수한 항균 효과와 경제적 효과가 기대된다.As can be seen from the above results, the extract of Root-derived Root Extract shows an excellent antimicrobial effect compared to other plant extracts, and at least one of Lavender Oil, Rosemary Oil, Tea Tree Oil, Peppermint Oil, Lemon Oil, and Juniper Oil When used together, excellent antimicrobial and economic effects are expected.
본 발명에 의한 화장료를 제조하는 방법을 구체적인 실시예로써 설명하면 다음과 같다.Referring to the method for producing a cosmetic according to the present invention as a specific example as follows.
〈실시예 2〉- 본 발명에 의한 유근피추출물을 함유한 여드름피부용 화장료 제조 방법<Example 2>-A method for preparing a cosmetic for acne skin containing the root extract of the present invention
자유수 20.0중량% 기준으로 여기에 전술한 유근피추출물 1.0중량% 라벤더 오일 0.2중량%를 일정량의 에탄올과 같은 보조용매에 녹이거나 계면활성제에 혼합하여 이것에 수용성 성분을 첨가하여 실온에서 다시 10분간 강하게 교반하면서 서서히 가온하여 70도씨에서 용융된 유용성 성분 등 나머지 화장료 조성 성분들을 일반적인 화장료의 제조 방법 대로 유화 또는 가용화하여 냉각, 탈기하여 화장료로 제품화하면 된다.Based on 20.0% by weight of free water, 0.2% by weight of the above-mentioned 1.0% by weight of lavender extract and 0.2% by weight of lavender oil are dissolved in a predetermined amount of co-solvent such as ethanol or mixed with a surfactant. The remaining cosmetic composition components such as oil-soluble components melted at 70 degrees Celsius by gradually warming with stirring may be emulsified or solubilized according to a general cosmetic preparation method, and then cooled and degassed into a cosmetic product.
또한 본 발명의 유근피추출물을 함유하는 여드름 피부용 화장료 조성물을 구체적인 처방에 1~6을 통해 나타내면 아래와 같다.In addition, the cosmetic composition for acne skin containing the root-derived extract of the present invention is shown in the specific prescription through 1 to 6 as follows.
〈처방예 1〉- 크림(Cream)〈Prescription 1〉-Cream
〈처방예 2〉- 유연화장수(Skin Toner).〈Prescription 2〉 -Skin Toner.
〈처방예 3〉- 수렴 화장수(Astringent)〈Prescription Example 3〉 Astringent
〈처방예 4〉- 밀크 로션(Milk Lotion)Prescription 4-Milk Lotion
〈처방예 5〉- 유액상 파운데이션(Liquid Foundation)Prescription 5-Liquid Foundation
〈처방예 6〉- 비누(Soap)〈Prescription 6〉-Soap
이상과 같은 본 발명에 의한 유근피추출물을 함유하는 여드름 피부용 화장료 조성물의 여드름 피부에 대한 치료 효과를 임상적으로 측정하기 위해 실시예1의 항균성 활성성분인 유근피추출물과 라벤더 오일을 함유하는 본 발명의 화장료조성물(처방예1)과 종래 처방의 화장료 조성물(대조용)을 크림으로 각각 제조하여 여드름 보유자를 대상으로 임상 실험을 하였다. 즉, 발진성 여드름을 가진 사람 25명과 화농성 여드름을 가진 사람 15명이 남녀 비율 15 : 25로 구성된 피실험자를 대상으로 상기 2가지 크림을 매일 2~3회, 15일간 사용하면서 여드름 치료 상태를 육안으로 관찰하여 그 효과를 판정하여 표2와 같은 결과를 얻었다.In order to clinically measure the therapeutic effect of acne skin cosmetic composition containing the root-derived extract according to the present invention as described above, the cosmetic composition of the present invention containing the root-derived extract and lavender oil which are the antimicrobial active ingredients of Example 1 A composition (prescription example 1) and a cosmetic composition (control) of the conventional prescription were prepared as creams, respectively, and clinical trials were carried out with acne holders. That is, 25 people with rash acne and 15 people with purulent acne observed the acne treatment visually while using the two creams two to three times daily for 15 days. The effect was determined to obtain the results shown in Table 2.
또한 본 발명에 의한 화장료 조성물의 여드름 치료 효과는 표2에 나타난 바와 같이 매우 양호한 것으로 판명되었다. 또한 이들 유근피추출물과 아로마 정유는 여드름 이외에 일반 피부명을 유발하는 병원균들에 대해서도 생장 억제 효과가 있는 것으로 확인되었다. 이러한 모든 결과를 두고 볼 때, 본 발명에 의한 유근피추출물을 함유하는 여드름 피부용 화장료는 종래 처방의 화장료에 비해 여드름 피부에 대해 우수한 치유 효과를 가진다.In addition, the acne treatment effect of the cosmetic composition according to the present invention was found to be very good as shown in Table 2. In addition, these root extracts and aromatic essential oils were found to have growth inhibitory effects on pathogens that cause general skin name in addition to acne. In view of all these results, the cosmetic for acne skin containing the root-derived extract according to the present invention has an excellent healing effect on acne skin compared to the cosmetics of the conventional prescription.
Claims (3)
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| KR100987561B1 (en) * | 2008-07-22 | 2010-10-12 | 주식회사 이피텍 | Opening and closing device of homebar door for refrigerator |
| KR101333676B1 (en) * | 2013-07-11 | 2013-11-27 | 주식회사 더마랩 | Cosmetic composition for reducing skin pore size and secreting sebum containing the extract of oenothera odorata jacq., pueraria radix, pine tree leaves and ulmus pumila l |
| KR20180118487A (en) * | 2017-04-21 | 2018-10-31 | 코스맥스 주식회사 | Cosmetic Composition Comprising Tea Tree Oil, Stick-form Cosmetics For Improving Acne Symptom Using Thereof, And Method For Preparing Thereof |
| KR20210061841A (en) * | 2019-11-20 | 2021-05-28 | 주식회사 텐핑 | Cosmetic composition having antioxidant and antibacterial activity and manufacturing method thereof |
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| KR960021002A (en) * | 1994-12-23 | 1996-07-18 | 성재갑 | Radical scavenger containing extract of elm and anti-aging cosmetic composition containing same |
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| KR960021002A (en) * | 1994-12-23 | 1996-07-18 | 성재갑 | Radical scavenger containing extract of elm and anti-aging cosmetic composition containing same |
| KR970064595A (en) * | 1996-03-21 | 1997-10-13 | 신재후 | A cosmetic cleansing composition containing a milky skin extract |
| KR20020015587A (en) * | 2000-08-22 | 2002-02-28 | 오세군 | Compositions of cosmetics for acned skin containing antiseptic herbal extracts |
| KR20010109227A (en) * | 2000-10-21 | 2001-12-08 | 정두석 | Soap composition containing the Chinese herb extract and preparation there of |
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| KR100987561B1 (en) * | 2008-07-22 | 2010-10-12 | 주식회사 이피텍 | Opening and closing device of homebar door for refrigerator |
| KR101333676B1 (en) * | 2013-07-11 | 2013-11-27 | 주식회사 더마랩 | Cosmetic composition for reducing skin pore size and secreting sebum containing the extract of oenothera odorata jacq., pueraria radix, pine tree leaves and ulmus pumila l |
| KR20180118487A (en) * | 2017-04-21 | 2018-10-31 | 코스맥스 주식회사 | Cosmetic Composition Comprising Tea Tree Oil, Stick-form Cosmetics For Improving Acne Symptom Using Thereof, And Method For Preparing Thereof |
| KR20210061841A (en) * | 2019-11-20 | 2021-05-28 | 주식회사 텐핑 | Cosmetic composition having antioxidant and antibacterial activity and manufacturing method thereof |
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