KR102012000B1 - Coating composition for infection control of tattoo area and method of preparing the same - Google Patents

Coating composition for infection control of tattoo area and method of preparing the same Download PDF

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KR102012000B1
KR102012000B1 KR1020180005486A KR20180005486A KR102012000B1 KR 102012000 B1 KR102012000 B1 KR 102012000B1 KR 1020180005486 A KR1020180005486 A KR 1020180005486A KR 20180005486 A KR20180005486 A KR 20180005486A KR 102012000 B1 KR102012000 B1 KR 102012000B1
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mixture
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rotavapor
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김경희
송혜주
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김경희
송혜주
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    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
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    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89Polysiloxanes
    • A61K8/891Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00Make-up preparations; Body powders; Preparations for removing make-up
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
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Abstract

본 발명은 문신 시술 후, 문신이 새겨진 피부 주변으로 스프레이 방식으로 뿌려줌으로써 필름 박막을 형성하여, 문신 부위를 통해 세균 등이 침투하는 것을 차단하고, 항균·항산화, 피부보습, 자외선 차단 기능 및 피부진정으로 인해 피부 상태를 향상시킴으로써 문신 시술의 안정성을 더욱 향상시킬 수 있도록 하는 문신 부위 감염방지용 코팅 조성물 및 이의 제조방법에 관한 것이다.The present invention forms a film thin film by spraying around the tattooed skin after the tattoo treatment, forming a film thin film, blocking the penetration of bacteria, etc. through the tattoo site, antibacterial, antioxidant, skin moisturizing, sun protection and skin soothing Therefore, the present invention relates to a coating composition for preventing infection of a tattoo site and a method for manufacturing the same, which may further improve the stability of a tattoo procedure by improving a skin condition.

Description

문신 부위 감염방지용 코팅 조성물 및 이의 제조방법{COATING COMPOSITION FOR INFECTION CONTROL OF TATTOO AREA AND METHOD OF PREPARING THE SAME}Coating composition for preventing tattoo site infection and manufacturing method therefor {COATING COMPOSITION FOR INFECTION CONTROL OF TATTOO AREA AND METHOD OF PREPARING THE SAME}

본 발명은 문신 시술 후, 문신이 새겨진 피부 주변으로 스프레이 방식으로 뿌려줌으로써 필름 박막을 형성하여, 문신 부위를 통해 세균 등이 침투하는 것을 차단하고, 항균·항산화, 피부보습, 자외선 차단 기능 및 피부진정으로 인해 피부 상태를 향상시킴으로써 문신 시술의 안정성을 더욱 향상시킬 수 있도록 하는 문신 부위 감염방지용 코팅 조성물 및 이의 제조방법에 관한 것이다.The present invention forms a film thin film by spraying around the tattooed skin after the tattoo treatment, forming a film thin film, blocking the penetration of bacteria, etc. through the tattoo site, antibacterial, antioxidant, skin moisturizing, sun protection and skin soothing Therefore, the present invention relates to a coating composition for preventing infection of a tattoo site and a method for manufacturing the same, which may further improve the stability of a tattoo procedure by improving a skin condition.

문신은 사람의 살갗에 상처를 내어 색깔이 있는 염료를 피부의 깊은 층 즉, 진피 속에 집어넣는 것으로 글자나 문양(무늬) 또는 그림을 새겨 넣는 것을 말한다.A tattoo is a process of injuring a person's skin and placing colored dye into a deep layer of the skin, the dermis, inscribed with letters, patterns, or pictures.

본 발명은 문신 시술 후 세균 등에 의해 감염되는 것을 미연이 방지하고자 하는 것으로서, 조성물을 문신이 새겨진 피부 주변으로 뿌려줌으로서 코팅 피막이 형성되어 1차적으로 세균이 침투하는 것을 차단하고, 더 나아가 항균·항산화, 피부보습, 자외선 차단 기능 및 피부진정 효과에 의한 피부의 건강 상태를 향상시킬 수 있도록 하는 것이다.The present invention is intended to prevent infection by bacteria and the like after tattooing, the coating coating is formed by spraying the composition around the skin engraved tattoos to block the first penetration of bacteria, furthermore antibacterial and antioxidant To improve the health of the skin by skin moisturizing, sun protection and soothing effects.

본 발명과 관련하여, 대한민국 공개특허 10-2005-0091651(공개일자 2005.09.15)의 '피부코팅용 피막제 조성물 및 자화장치'에 대한 기술이 개시된 바 있으나, 상기 공개특허는 피부에 도포한 외용제를 물리적 회손 으로부터 보호함과 방향성물질의 외부 휘산 을 통제하며 환부에 자연치유력을 유도하기 위한 것으로서, 본 발명에서 제시하고자 하는 문신 부위 감염방지와 피부 상태 개선을 위한 조성물로 적용하기에 적합하지 않다.In connection with the present invention, the technology of 'skin coating composition and magnetization device for skin coating' of the Republic of Korea Patent Publication No. 10-2005-0091651 (published date 2005.09.15) has been disclosed, but the patent discloses an external preparation applied to the skin To protect against physical damage and to control the external volatilization of aromatic substances and to induce natural healing in the affected area, it is not suitable for application as a composition for preventing tattoo site infection and improving skin condition to be proposed in the present invention.

대한민국 공개특허 10-2005-0091651(공개일자 2005.09.15)Republic of Korea Patent Publication 10-2005-0091651 (published date 2005.09.15)

본 발명은 문신 시술 후, 문신이 새겨진 피부 주변으로 스프레이 방식으로 뿌려줌으로써 필름 박막을 형성하여, 문신 부위를 중심으로 세균 등의 침투를 막아주고, 항균·항산화, 피부보습, 자외선 차단 기능으로 인해 피부의 건강 상태를 향상시킴으로써 문신 시술의 안정성을 확보할 수 있도록 하는 문신 부위 감염방지용 코팅 조성물 및 이의 제조방법을 제공하고자 하는 것을 발명의 목적으로 한다.The present invention forms a thin film film by spraying around the tattooed skin after the tattoo treatment, to prevent the penetration of bacteria, etc. around the tattoo area, the skin due to antibacterial, antioxidant, skin moisturizing, UV protection It is an object of the present invention to provide a coating composition for preventing infection of a tattoo site and a method for preparing the same, which can ensure the stability of a tattoo procedure by improving a health condition of the tattoo.

상기 목적을 달성하기 위하여,In order to achieve the above object,

본 발명은,The present invention,

정제수(Water)(a) 89.0 ~ 95.0 wt%;Purified water (a) 89.0-95.0 wt%;

폴리비닐알코올(Polyvinyl alcohol)(b) 3.0 ~ 6.0 wt%;Polyvinyl alcohol (b) 3.0 to 6.0 wt%;

디메치콘(Dimethicone)(c) 1.0 ~ 3.0 wt%;Dimethicone (c) 1.0-3.0 wt%;

에틸헥실글리세린(Ethylhexylglycerin)(d) 0.1 ~ 2.0 wt%;Ethylhexylglycerin (d) 0.1-2.0 wt%;

1,2-헥산다이올(1,2-Hexanediol)(e) 0.1 ~ 2.0 wt%;1,2-hexanediol (1,2-Hexanediol) (e) 0.1-2.0 wt%;

하이드록시에틸셀룰로스의 점증제(f) 0.1 ~ 0.5 wt%;0.1 to 0.5 wt% thickener (f) of hydroxyethylcellulose;

건조시킨 산수유 열매와 잎을 동중량비율로 혼합하여 혼합물을 조성하고, 상기 혼합물을 20 ~ 50 배의 증류수에 첨가한 후 35 ~ 39 ℃에서 150 ~ 300 rpm으로 1 ~ 48 시간 동안 진탕 추출하고, 추출하여 수득한 용액을 필터로 여과한 여액을 회전증발농축기(Rotavapor)로 농축하여 제조된 산수유 추출물 10 ~ 50 wt%와,The dried cornus fruit and leaves were mixed at the same weight ratio to form a mixture, and the mixture was added to 20 to 50 times distilled water, followed by shaking extraction at 150 to 300 rpm at 35 to 39 ° C. for 1 to 48 hours. 10 ~ 50 wt% of the cornus extract, which was prepared by concentrating the filtrate filtered with a filter and filtered through a rotavapor;

동결건조 후 마쇄한 천년초 열매 분말을 물(water)과 1 : 10 ~ 30 중량비가 되도록 첨가한 후, 28 ~ 32 ℃에서 22 ~ 26 시간 동안 추출하여 수득한 용액을 원심분리기를 이용하여 10,000 ~ 13,000 rpm으로 15 ~ 30 분 동안 원심분리한 후, 상등액을 필터로 여과한 여액을 회전증발농축기(Rotavapor)로 농축하여 제조된 천년초 추출물 10 ~ 50 wt%과,After freeze-drying, the milled cheonnyeoncho fruit powder was added with water (water) in a ratio of 1: 10 to 30, and then the solution obtained by extracting at 28 to 32 ° C. for 22 to 26 hours using a centrifuge was used at 10,000 to 13,000. After centrifugation for 15 to 30 minutes at 10 rpm, the filtrate filtered with supernatant was filtered using a rotavapor, and 10 to 50 wt% of cheonnyeoncho extract,

어성초를 에탄올과 1 : 5 ~ 15 중량비로 23 ~ 27 ℃에서 20 ~ 30 시간 동안 침지한 후 상층액과 침전물을 분리하는 일련의 과정을 2 ~ 4 회 반복 추출하여 수득한 용액을 원심분리기를 이용하여 10,000 ~ 13,000 rpm으로 15 ~ 30 분 동안 원심분리한 후, 상등액을 필터로 여과한 여액을 회전증발농축기(Rotavapor)로 농축하여 제조된 어성초 추출물 10 ~ 50 wt%의 혼합으로 조성된 100 wt%의 천연항산화·항균추출물(g) 0.1 ~ 5.0 wt%; The solution obtained by immersing Echoseongcho and ethanol at 1: 5 to 15 weight ratio for 20 to 30 hours at 23 to 27 ℃ for 20 to 30 hours and then repeatedly extracting a series of processes of separating supernatant and precipitate 2 to 4 times using a centrifuge After centrifugation at 10,000 ~ 13,000 rpm for 15 to 30 minutes, the supernatant was filtered with a filter and concentrated by Rotavapor, Eochocho extract prepared by mixing 10 ~ 50 wt% 100 wt% Natural antioxidant and antibacterial extract of (g) 0.1 ~ 5.0 wt%;

분쇄한 복령과 에탄올을 1: 5 ~ 20 중량비로 혼합한 후, 초음파(Sonication) 추출하여 수득한 용액을 필터처리한 후, 그 여액을 회전증발농축기(Rotavapor)로 농축하여 제조된 복령추출물 10 ~ 50 wt%와,After mixing the pulverized Bokryeong and ethanol 1: 5 to 20 by weight ratio, and filter the solution obtained by ultrasonic extraction (Sonication), the filtrate was concentrated by a rotary evaporator (Rotavapor) to prepare a Fukryeong extract 10 ~ With 50 wt%,

수련 줄기와 잎을 동 중량비율로 혼합한 후, 수분함량이 5 wt% 이하가 되도록 63 ~ 68 ℃에서 6 ~ 10 시간 동안 건조하고, 건조한 수련혼합물을 80 % 에탄올과 1 : 5 ~ 20 중량비로 혼합하여 75 ~ 85 ℃의 수욕상에서 2 ~ 4 시간 동안 환류냉각 추출하는 과정을 2 ~ 4 회 반복하여 수득한 용액을 필터처리한 후, 그 여액을 회전증발농축기(Rotavapor)로 농축하여 제조된 수련추출물 10 ~ 50 wt%와,After mixing the water lily stem and the leaves at the same weight ratio, the water content was dried at 63 ~ 68 ℃ for 6 to 10 hours so that the water content is 5 wt% or less, and the dried water lily mixture with 80% ethanol and 1: 5 to 20 weight ratio After mixing and filtering the solution obtained by repeating the reflux cooling extraction for 2 to 4 hours in a water bath at 75 to 85 ° C. for 2 to 4 times, the filtrate was concentrated by a rotary evaporator. With 10-50 wt% of extract,

해삼과 에탄올을 1 : 5 ~ 15 중량비율로 혼합한 후, 25 ~ 28 ℃, 20 ~ 30 시간 동안 130 ~ 170 rpm으로 진탕배양기에서 추출한 용액을 원심분리기에서 7,500 ~ 8,500 rpm으로 15 ~ 25 분 동안 원심분리하여 수득한 상층액을 회전증발농축기(Rotavapor)로 농축하여 제조된 해삼추출물 10 ~ 50 wt%의 혼합으로 조성된 100 wt%의 천연보습추출물(h) 0.1 ~ 5.0 wt%; After mixing sea cucumber and ethanol at a weight ratio of 1: 5 to 15, the solution extracted from the shaker at 130 to 170 rpm for 25 to 28 ° C. and 20 to 30 hours for 15 to 25 minutes at 7,500 to 8,500 rpm in a centrifuge 100 wt% natural moisturizing extract (h) prepared by mixing 10-50 wt% of sea cucumber extract prepared by concentrating the supernatant obtained by centrifugation with a rotary evaporator (Rotavapor);

고삼 10 ~ 35 wt%와, 구척 10 ~ 35 wt%와, 대황 10 ~ 35 wt%와, 비자 10 ~ 35 wt%를 혼합한 후 마쇄하고, 마쇄한 혼합물을 90 % 메탄올과 1 : 5 ~ 20 중량비로 혼합하여 20 ~ 30 ℃, 150 ~ 300 rpm으로 5 ~ 60 시간 동안 진탕 추출하고, 추출하여 수득한 용액을 필터를 이용하여 여과한 여액을 회전증발농축기(Rotavapor)로 농축하여 제조된 천연자외선차단추출물(i) 0.1 ~ 5.0 wt%;의 혼합(a+b+c+d+e+f+g+h+i)으로 조성된 것임을 특징으로 하는 문신 부위 감염방지용 코팅 조성물을 제공한다.10 to 35 wt% of red ginseng, 10 to 35 wt% of ginseng, 10 to 35 wt% of rhubarb, and 10 to 35 wt% of non-visible powder, followed by grinding. The ground mixture was ground with 90% methanol and 1: 5 to 20 Natural ultraviolet rays prepared by mixing by weight ratio and shaking extraction at 20 ~ 30 ℃, 150 ~ 300 rpm for 5 to 60 hours, and concentrating the filtrate filtered by using a filter with a rotary evaporator (Rotavapor) Block extract (i) provides a coating composition for preventing infection of the tattoo site, characterized in that it is composed of a mixture (a + b + c + d + e + f + g + h + i) of 0.1 ~ 5.0 wt%.

그리고 And

산수유 추출물 10 ~ 50 wt%, 천년초 추출물 10 ~ 50 wt%, 어성초 추출물 10 ~ 50 wt%를 혼합하여 천연항산화·항균추출물을 제조하는 단계와,Preparing a natural antioxidant and antibacterial extract by mixing 10 ~ 50 wt% cornus extract, 10 ~ 50 wt% cheonnyeoncho extract, 10 ~ 50 wt% Eochocho extract;

복령추출물 10 ~ 50 wt%, 수련추출물 10 ~ 50 wt%, 수련추출물 10 ~ 50 wt%, 해삼추출물 10 ~ 50 wt%를 혼합하여 천연보습추출물을 조성하는 단계와,Forming a natural moisturizing extract by mixing 10 to 50 wt% of Fuling extract, 10 to 50 wt% of water lily extract, 10 to 50 wt% of water lily extract, and 10 to 50 wt% of sea cucumber extract;

고삼 10 ~ 35 wt%와, 구척 10 ~ 35 wt%와, 대황 10 ~ 35 wt%와, 비자 10 ~ 35 wt%의 혼합물로부터 천연자외선차단추출물을 제조하는 단계와,Preparing a natural ultraviolet cut extract from a mixture of 10 to 35 wt% of red ginseng, 10 to 35 wt% of ginseng, 10 to 35 wt% of rhubarb, and 10 to 35 wt% of non-visible,

정제수(Water) 89.0 ~ 95.0 wt%, 폴리비닐알코올(Polyvinyl alcohol) 3.0 ~ 6.0 wt%, 디메치콘(Dimethicone) 1.0 ~ 3.0 wt%, 에틸헥실글리세린(Ethylhexylglycerin) 0.1 ~ 2.0 wt%, 1,2-헥산다이올(1,2-Hexanediol) 0.1 ~ 2.0 wt%, 하이드록시에틸셀룰로스의 점증제 0.1 ~ 0.5 wt%, 천연항산화·항균추출물 0.1 ~ 5.0 wt%, 천연보습추출물 0.1 ~ 5.0 wt%, 천연자외선차단추출물 0.1 ~ 5.0 wt%을 혼합하여 코팅 조성물용 혼합물을 조성하는 단계와,Water 89.0 ~ 95.0 wt%, Polyvinyl alcohol 3.0 ~ 6.0 wt%, Dimethicone 1.0 ~ 3.0 wt%, Ethylhexylglycerin 0.1 ~ 2.0 wt%, 1,2- Hexanediol (1,2-Hexanediol) 0.1 ~ 2.0 wt%, hydroxyethyl cellulose thickener 0.1 ~ 0.5 wt%, natural antioxidant and antibacterial extract 0.1 ~ 5.0 wt%, natural moisturizing extract 0.1 ~ 5.0 wt%, natural Mixing the sunscreen extract with 0.1 to 5.0 wt% to form a mixture for the coating composition;

상기 혼합물을 500 rpm ~ 1,000 rpm으로 1 ~ 3시간 동안 교반하는 단계와,Stirring the mixture at 500 rpm to 1,000 rpm for 1 to 3 hours,

상기 교반과정을 거친 코팅 조성물용 혼합물을 200 ~ 500 mesh의 망에 넣어 가압하여 여과하는 단계를 포함하여 이루어지는 문신 부위 감염방지용 코팅 조성물 제조방법을 제공한다.It provides a method for producing a coating composition for preventing tattoo site infection comprising the step of filtering the mixture for the coating composition after the stirring process into a network of 200 ~ 500 mesh under pressure.

본 발명에 따른 문신 부위 감염방지용 코팅 조성물은 다음의 효과를 갖는다.Tattoo site infection prevention coating composition according to the present invention has the following effects.

첫째. 문신 시술 후 문신 부위를 중심으로 스프레이 방식으로 간편하게 뿌려줌으로써 문신 부위에 필름 박막이 형성되어 세균이 문신 부위를 통해 인체로 침투하는 것을 차단하여 세균감염 예방효과가 뛰어나다.first. After tattooing, the spraying method is easily sprayed around the tattoo area to form a film thin film on the tattoo area to prevent bacteria from penetrating into the human body through the tattoo area, thus preventing bacterial infection.

둘째. 자체 항산화·항균 기능에 의해 피부의 노화, 피부 오염의 억제효과를 갖는다.second. Its own antioxidant and antibacterial function has the effect of inhibiting skin aging and skin contamination.

셋째. 피부보습 및 자외선 차단 기능에 의한 피부 건강상태를 향상시키는 효과를 갖는다.third. It has the effect of improving skin health by skin moisturizing and sun protection.

넷째. 피부 진정효과를 부여함으로써 문신 시술 후의 피부 자극을 최소화할 수 있다.fourth. By giving the skin soothing effect, it can minimize the skin irritation after tattooing.

본 발명에 따른 기술 구성에 대한 구체적인 내용을 살펴보도록 한다.It looks at the details of the technical configuration according to the present invention.

상기한 바와 같이,As mentioned above

본 발명에 따른 문신 부위 감염방지용 코팅 조성물은,Tattoo site infection prevention coating composition according to the present invention,

정제수(Water)(a) 89.0 ~ 95.0 wt%;Purified water (a) 89.0-95.0 wt%;

폴리비닐알코올(Polyvinyl alcohol)(b) 3.0 ~ 6.0 wt%;Polyvinyl alcohol (b) 3.0 to 6.0 wt%;

디메치콘(Dimethicone)(c) 1.0 ~ 3.0 wt%;Dimethicone (c) 1.0-3.0 wt%;

에틸헥실글리세린(Ethylhexylglycerin)(d) 0.1 ~ 2.0 wt%;Ethylhexylglycerin (d) 0.1-2.0 wt%;

1,2-헥산다이올(1,2-Hexanediol)(e) 0.1 ~ 2.0 wt%;1,2-hexanediol (1,2-Hexanediol) (e) 0.1-2.0 wt%;

하이드록시에틸셀룰로스의 점증제(f) 0.1 ~ 0.5 wt%;0.1 to 0.5 wt% thickener (f) of hydroxyethylcellulose;

건조시킨 산수유 열매와 잎을 동중량비율로 혼합하여 혼합물을 조성하고, 상기 혼합물을 20 ~ 50 배의 증류수에 첨가한 후 35 ~ 39 ℃에서 150 ~ 300 rpm으로 1 ~ 48 시간 동안 진탕 추출하고, 추출하여 수득한 용액을 필터를 이용하여 여과한 여액을 회전증발농축기(Rotavapor)로 농축하여 제조된 산수유 추출물 10 ~ 50 wt%와,The dried cornus fruit and leaves were mixed at the same weight ratio to form a mixture, and the mixture was added to 20 to 50 times distilled water, followed by shaking extraction at 150 to 300 rpm at 35 to 39 ° C. for 1 to 48 hours. 10-50 wt% of the cornus extract, prepared by concentrating the filtrate filtered using a filter and extracting the filtrate with a rotavapor;

동결건조 후 마쇄한 천년초 열매 분말을 물(water)과 1 : 10 ~ 30 중량비가 되도록 첨가한 후, 28 ~ 32 ℃에서 22 ~ 26 시간 동안 추출하여 수득한 용액을 원심분리기를 이용하여 10,000 ~ 13,000 rpm으로 15 ~ 30 분 동안 원심분리한 후, 상등액을 필터로 여과한 여액을 회전증발농축기(Rotavapor)로 농축하여 제조된 천년초 추출물 10 ~ 50 wt%과,After freeze-drying, the milled cheonnyeoncho fruit powder was added with water (water) in a ratio of 1: 10 to 30, and then the solution obtained by extracting at 28 to 32 ° C. for 22 to 26 hours using a centrifuge was used at 10,000 to 13,000. After centrifugation for 15 to 30 minutes at 10 rpm, the filtrate filtered with supernatant was filtered using a rotavapor, and 10 to 50 wt% of cheonnyeoncho extract,

어성초를 에탄올과 1 : 5 ~ 15 중량비로 23 ~ 27 ℃에서 20 ~ 30 시간 동안 침지한 후 상층액과 침전물을 분리하는 일련의 과정을 2 ~ 4 회 반복 추출하여 수득한 용액을 원심분리기를 이용하여 10,000 ~ 13,000 rpm으로 15 ~ 30 분 동안 원심분리한 후, 상등액을 필터로 여과한 여액을 회전증발농축기(Rotavapor)로 농축하여 제조된 어성초 추출물 10 ~ 50 wt%의 혼합으로 조성된 100 wt%의 천연항산화·항균추출물(g) 0.1 ~ 5.0 wt%; The solution obtained by immersing Echoseongcho and ethanol at 1: 5 to 15 weight ratio for 20 to 30 hours at 23 to 27 ℃ for 20 to 30 hours and then repeatedly extracting a series of processes of separating supernatant and precipitate 2 to 4 times using a centrifuge After centrifugation at 10,000 ~ 13,000 rpm for 15 to 30 minutes, the supernatant was filtered with a filter and concentrated by Rotavapor, Eochocho extract prepared by mixing 10 ~ 50 wt% 100 wt% Natural antioxidant and antibacterial extract of (g) 0.1 ~ 5.0 wt%;

분쇄한 복령과 에탄올을 1: 5 ~ 20 중량비로 혼합한 후, 초음파(Sonication) 추출하여 수득한 용액을 필터처리한 후, 그 여액을 회전증발농축기(Rotavapor)로 농축하여 제조된 복령추출물 10 ~ 50 wt%와,After mixing the pulverized Bokryeong and ethanol 1: 5 to 20 by weight ratio, and filter the solution obtained by ultrasonic extraction (Sonication), the filtrate was concentrated by a rotary evaporator (Rotavapor) to prepare a Fukryeong extract 10 ~ With 50 wt%,

수련 줄기와 잎을 동 중량비율로 혼합한 후, 수분함량이 5 wt% 이하가 되도록 63 ~ 68 ℃에서 6 ~ 10 시간 동안 건조하고, 건조한 수련혼합물을 80 % 에탄올과 1 : 5 ~ 20 중량비로 혼합하여 75 ~ 85 ℃의 수욕상에서 2 ~ 4 시간 동안 환류냉각 추출하는 과정을 2 ~ 4 회 반복하여 수득한 용액을 필터처리한 후, 그 여액을 회전증발농축기(Rotavapor)로 농축하여 제조된 수련추출물 10 ~ 50 wt%와,After mixing the water lily stem and the leaves at the same weight ratio, the water content was dried at 63 ~ 68 ℃ for 6 to 10 hours so that the water content is 5 wt% or less, and the dried water lily mixture with 80% ethanol and 1: 5 to 20 weight ratio After mixing and filtering the solution obtained by repeating the reflux cooling extraction for 2 to 4 hours in a water bath at 75 to 85 ° C. for 2 to 4 times, the filtrate was concentrated by a rotary evaporator. With 10-50 wt% of extract,

해삼과 에탄올을 1 : 5 ~ 15 중량비율로 혼합한 후, 25 ~ 28 ℃, 20 ~ 30 시간 동안 130 ~ 170 rpm으로 진탕배양기에서 추출한 용액을 원심분리기에서 7,500 ~ 8,500 rpm으로 15 ~ 25 분 동안 원심분리하여 수득한 상층액을 회전증발농축기(Rotavapor)로 농축하여 제조된 해삼추출물 10 ~ 50 wt%의 혼합으로 조성된 100 wt%의 천연보습추출물(h) 0.1 ~ 5.0 wt%; After mixing sea cucumber and ethanol at a weight ratio of 1: 5 to 15, the solution extracted from the shaker at 130 to 170 rpm for 25 to 28 ° C. and 20 to 30 hours for 15 to 25 minutes at 7,500 to 8,500 rpm in a centrifuge 100 wt% natural moisturizing extract (h) prepared by mixing 10-50 wt% of sea cucumber extract prepared by concentrating the supernatant obtained by centrifugation with a rotary evaporator (Rotavapor);

고삼 10 ~ 35 wt%와, 구척 10 ~ 35 wt%와, 대황 10 ~ 35 wt%와, 비자 10 ~ 35 wt%를 혼합한 후 마쇄하고, 마쇄한 혼합물을 90 % 메탄올과 1 : 5 ~ 20 중량비로 혼합하여 20 ~ 30 ℃, 150 ~ 300 rpm으로 5 ~ 60 시간 동안 진탕 추출하고, 추출하여 수득한 용액을 필터를 이용하여 여과한 여액을 회전증발농축기(Rotavapor)로 농축하여 제조된 천연자외선차단추출물(i) 0.1 ~ 5.0 wt%;의 혼합(a+b+c+d+e+f+g+h+i)으로 조성된다.10 to 35 wt% of red ginseng, 10 to 35 wt% of ginseng, 10 to 35 wt% of rhubarb, and 10 to 35 wt% of non-visible powder, followed by grinding. The ground mixture was ground with 90% methanol and 1: 5 to 20 Natural ultraviolet rays prepared by mixing by weight ratio and shaking extraction at 20 ~ 30 ℃, 150 ~ 300 rpm for 5 to 60 hours, and concentrating the filtrate filtered by using a filter with a rotary evaporator (Rotavapor) Block extract (i) 0.1 ~ 5.0 wt%; is mixed with (a + b + c + d + e + f + g + h + i).

상기 폴리비닐알코올(Polyvinyl alcohol)은 폴리비닐알코올(PVA)은 일반적으로 초산비닐 모노머를 라디칼 중합으로 알칼리 검화(saponification)하여 제조한다. PAV는 합성고분자 둥에서 수용성이라는 특이한 성질을 가지고 있다. 백색 분말로 비중이 0.3 ~ 0.7이다. 검화도(Degree of saponification DS)는 PVA의 특성을 결정짓는 중요한 요소이다. 점화도가 높은 경우 분자간의 수소결합이 강하여 융점이 높고 물에 용해되기 어렵고, 온수(75 ℃ 이상)에는 팽윤되거나 녹지만 냉수에는 난용성이다. 본 발명에서 상기 폴리비닐알코올(Polyvinyl alcohol)은 디메치콘(Dimethicone)과 함께 필름형 박막을 형성하는 역할을 한다.The polyvinyl alcohol (Polyvinyl alcohol) is polyvinyl alcohol (PVA) is generally prepared by alkaline saponification of vinyl acetate monomer by radical polymerization. PAV has the unique property of being water soluble in synthetic polymers. White powder with specific gravity 0.3-0.7. Degree of saponification DS is an important factor in determining the characteristics of PVA. If the ignition degree is high, the hydrogen bond between the molecules is strong, the melting point is high, it is difficult to dissolve in water, swelling or melting in hot water (75 ℃ or more), but poorly soluble in cold water. In the present invention, the polyvinyl alcohol (Polyvinyl alcohol) serves to form a film-like thin film with dimethicone (Dimethicone).

상기 폴리비닐알코올(Polyvinyl alcohol)의 함량이 3.0 wt% 미만인 경우에는 이와 같은 필름 박막의 형성이 제대로 이루어지기 어렵고, 6.0 wt%를 초과하게 되는 경우에는 필요 이상의 사용으로 인해 불필요하므로, 상기 폴리비닐알코올(Polyvinyl alcohol)의 사용량은 조성물의 전체 중량에 대해 3.0 ~ 6.0 wt%의 범위 내로 한정하는 것이 바람직하다.When the content of the polyvinyl alcohol (polyvinyl alcohol) is less than 3.0 wt%, it is difficult to form such a film thin film properly, and when the content exceeds 6.0 wt%, since it is unnecessary due to use more than necessary, the polyvinyl alcohol (Polyvinyl alcohol) is preferably used in the range of 3.0 to 6.0 wt% based on the total weight of the composition.

상기 디메치콘(Dimethicone)은 밀폐형 보습제로서, 화장품에 적용하여 사용감이 좋고 피부에 끈적임을 주지 않으며 막을 형성하여 피부를 보호하는 역할을 한다.The dimethicone (Dimethicone) is a hermetic moisturizing agent, applied to cosmetics and does not give a good feeling to the skin and does not stick to the skin to form a film to protect the skin.

이와 같은 기능을 갖는 상기 디메치콘(Dimethicone)의 사용량이 1.0 wt% 미만인 경우에는 막의 형성에 의한 피부 보호기능성이 떨어지고, 3.0 wt%를 초과하게 되는 경우에는 상대적으로 다른 성분들의 함량이 줄어들어 전체적인 기능성의 저하 우려가 있으므로, 상기 디메치콘(Dimethicone)의 사용량은 조성물의 전체 중량에 대해 1.0 ~ 3.0 wt%의 범위 내로 한정하는 것이 바람직하다.When the amount of dimethicone having such a function is less than 1.0 wt%, the skin protection function due to the formation of a film is lowered, and when the amount of dimethicone exceeds 3.0 wt%, the content of other components is relatively reduced, thereby reducing the overall functional properties. Since there is a fear of deterioration, it is preferable to limit the amount of dimethicone used in the range of 1.0 to 3.0 wt% based on the total weight of the composition.

상기 에틸헥실글리세린(Ethylhexylglycerin)은 글리세릴에테르로 유기화합물 성분이며 글리세린의 한 종류로서 항균력을 증가시켜 준다. 따라서 본 발명에서는 화장품의 박테리아나 세균으로 오염되는 것을 막기 위한 보존제로 사용되며, 그 사용량이 0.1 wt% 미만인 경우에는 보존제로서의 기능성이 미미하고, 2.0 wt%를 초과하게 되는 경우에는 필요 이상의 사용으로 인해 무의미하므로, 상기 에틸헥실글리세린(Ethylhexylglycerin)의 사용량은 조성물의 전체 중량에 대해 0.1 ~ 2.0 wt%의 범위 내로 한정하는 것이 바람직하다.The ethylhexylglycerin (Ethylhexylglycerin) is an organic compound component of glyceryl ether and increases the antibacterial activity as one kind of glycerin. Therefore, in the present invention, it is used as a preservative to prevent contamination by bacteria or bacteria in cosmetics, when the amount is less than 0.1 wt%, the functionality as a preservative is insignificant, and when it exceeds 2.0 wt% due to the use more than necessary Since it is meaningless, the amount of the ethylhexylglycerin (Ethylhexylglycerin) is preferably limited to the range of 0.1 to 2.0 wt% based on the total weight of the composition.

상기 1,2-헥산다이올(1,2-Hexanediol)은 1,2-디하이드록시헥산으로도 불리우며, 직선형의 알킬 체인의 첫 번째와 두 번째의 알코올 기가 각각 하나씩 붙어있는 구조이다. 소수성 기와 친수성 기를 모두 갖는 계면활성제 구조를 가지고 있으며, 무취의 물질이다. 보습제이자 사용상 안전한 방부제이다.The 1,2-hexanediol (1,2-Hexanediol) is also called 1,2-dihydroxyhexane, and has a structure in which the first and second alcohol groups of the linear alkyl chain are attached one by one. It has a surfactant structure having both hydrophobic and hydrophilic groups and is an odorless substance. Moisturizer and safe preservative.

상기 1,2-헥산다이올(1,2-Hexanediol)의 사용량이 0.1 wt% 미만인 경우에는 보존, 방부제로서의 기능을 제대로 발휘하기 어렵고, 2.0 wt%를 초과하게 되는 경우에는 필요 이상의 사용으로 인해 무의미하므로, 상기 1,2-헥산다이올(1,2-Hexanediol)의 사용량은 조성물의 전체 중량에 대해 0.1 ~ 2.0 wt%의 범위 내로 한정하는 것이 바람직하다.When the amount of the 1,2-hexanediol is less than 0.1 wt%, it is difficult to properly function as a preservative and preservative, and when it exceeds 2.0 wt%, it is meaningless due to use more than necessary. Therefore, the amount of the 1,2-hexanediol (1,2-Hexanediol) is preferably limited to the range of 0.1 to 2.0 wt% based on the total weight of the composition.

상기 점증제인 하이드록시에틸셀룰로스는 감염방지용 코팅 조성물의 점도를 조절하기 위하여 사용하는 것으로서, 그 사용량이 0.1 wt% 미만인 경우에는 점도 조절기능이 미미하고, 0.5 wt%를 초과하게 되는 경우에는 점도 상승으로 인한 박막형성이 제대로 이루어지지 않을 수 있으므로, 상기 점증제인 하이드록시에틸셀룰로스의 사용량은 조성물의 전체 중량에 대해 0.1 ~ 0.5 wt%의 범위 내로 한정하는 것이 바람직하다.The thickener hydroxyethyl cellulose is used to adjust the viscosity of the coating composition for preventing infection, and when the amount thereof is less than 0.1 wt%, the viscosity control function is insignificant, and when the amount exceeds 0.5 wt%, the viscosity is increased. Since the thin film may not be properly formed, the amount of the hydroxyethyl cellulose which is the thickener is preferably limited within the range of 0.1 to 0.5 wt% based on the total weight of the composition.

상기 천연항산화·항균추출물은 조성물 전체 중량에 대해 0.1 ~ 5.0 wt%의 범위 내로 사용량이 한정되는 것으로서, 그 사용량이 0.1 wt% 미만인 경우에는 항산화·항균 기능성이 미미하고, 5.0 wt%를 초과하게 되는 경우에는 상대적으로 다른 성분들의 함량이 감소함으로써 박막형성, 보습, 자외선 차단 등의 기능성이 떨어질 우려가 있으므로, 상기 천연항산화·항균추출물의 사용량은 상기 제시된 함량 범위 내로 한정하는 것이 바람직하다.The natural antioxidant and antibacterial extract is limited in the amount used in the range of 0.1 to 5.0 wt% with respect to the total weight of the composition, when the amount is less than 0.1 wt%, the antioxidant and antibacterial function is insignificant, exceeding 5.0 wt%. In this case, since the content of other components is relatively reduced, there is a possibility that functionality such as thin film formation, moisturizing, UV protection, etc. may be degraded. Therefore, the amount of the natural antioxidant / antibacterial extract is preferably limited within the above-mentioned content range.

상기 천연항산화·항균추출물은 산수유 추출물 10 ~ 50 wt%, 천년초 추출물 10 ~ 50 wt% 및 어성초 추출물 10 ~ 50 wt%의 혼합으로 조성된다.The natural antioxidant and antibacterial extract is composed of a mixture of 10 ~ 50 wt% cornus extract, 10 ~ 50 wt% cheonnyeoncho extract and 10 ~ 50 wt% Eochocho extract.

더욱 구체적으로는, 산수유 추출물 50 wt%, 천년초 추출물 25 wt% 및 어성초 추출물 25 wt%의 혼합으로 조성된 것을 사용한다.More specifically, the composition consisting of a mixture of 50 wt% cornus extract, 25 wt% cheonnyeoncho extract and 25 wt% Eochocho extract are used.

산수유 열매는 길이 1.5 cm 내외인 장추원형의 모양으로 윤이 나고 거친 주름이 있는 대추모양의 암적자색 외관에 독특한 냄새와 신맛 및 약간의 단맛으로 인해 촉산초 라고도 불린다.Cornus fruit is also called Zhuchocho with its unique smell, sourness and slight sweetness, with a jujube-shaped dark reddish purple appearance with shiny and coarse wrinkles in the shape of a round shape of a cabbage that is about 1.5 cm long.

상기 과실의 주요 화학 성분은 gallicacid, malic acid, tartaric acid, ursolic acid, morroniside, loganin, sweroside, methylmonorroniside 등과 같은 iridoid 배당체 등이 보고되었고, tellimagrandin 1,2, 1,2,3-tri-O-galloyl-β-D-glucose, 1,2,6-tri-O-galloyl-β-D-glucose, 1,2,3,6-tetra-O-galloyl-β-D-glucose, gemin D, Cornusin A-G, 2,3-di-O-galloyl-D-glucose,1,7-di-Ogalloyl-D-sedoheptullose와 같은 탄닌류 등이 보고되었다. 그 중 malicacid, tartaricacid 등은 신맛을 나타내고 loganin,sweroside 등이 쓴맛을 나타내며 gallicacid 등 tannin 류가 있어 떫은맛을 나타낸다.The main chemical constituents of the fruit were reported iridoid glycosides such as gallicacid, malic acid, tartaric acid, ursolic acid, morroniside, loganin, sweroside, methylmonorroniside, and the like, tellimagrandin 1,2, 1,2,3-tri-O-galloyl -β-D-glucose, 1,2,6-tri-O-galloyl-β-D-glucose, 1,2,3,6-tetra-O-galloyl-β-D-glucose, gemin D, Cornusin AG , Tannins such as 2,3-di-O-galloyl-D-glucose and 1,7-di-Ogalloyl-D-sedoheptullose have been reported. Among them, malicacid and tartaricacid have sour taste, loganin and sweroside have bitter taste and tannins such as gallicacid have a bitter taste.

상기 산수유 추출물은 건조시킨 산수유 열매와 잎을 동중량비율로 혼합하여 혼합물을 조성하고, 상기 혼합물을 20 ~ 50 배의 증류수에 첨가한 후 35 ~ 39 ℃에서 150 ~ 300 rpm으로 1 ~ 48 시간 동안 진탕 추출하고, 추출하여 수득한 용액을 필터를 이용하여 여과한 여액을 회전증발농축기(Rotavapor)로 농축한 것을 사용한다.The cornus extract is mixed with the dried cornus fruit and leaves in the same weight ratio to form a mixture, and the mixture is added to 20 to 50 times distilled water and then for 1 to 48 hours at 150 to 300 rpm at 35 ~ 39 ℃ Shake extraction, and the solution obtained by extracting the filtrate filtered using a filter is concentrated using a rotary evaporator (Rotavapor).

더욱 구체적으로는, 70 ℃에서 건조하여 수분함량이 3 wt% 이하가 되도록 건조시킨 산수유 열매와 잎을 1 : 1 중량비율로 혼합하여 혼합물을 조성한다.More specifically, the mixture is formed by mixing the cornus fruit and leaves in a 1: 1 weight ratio, dried at 70 ° C. and dried to have a water content of 3 wt% or less.

상기 혼합물을 증류수에 첨가하되, 상기 혼합물과 증류수의 혼합비가 1 : 20 중량비가 되도록 첨가한다. 37 ℃에서 200 rpm으로 40 시간 동안 진탕 추출한다.The mixture is added to distilled water, but the mixing ratio of the mixture and distilled water is 1:20 by weight. Shake extraction at 37 ° C. at 200 rpm for 40 hours.

상기 진탕 추출하여 수득한 용액을 필터(Whatman No.2 filter paper)로 여과한 후, 그 여액을 회전증발농축기(Rotavapor)로 농축한다.The solution obtained by shaking extraction was filtered with a filter (Whatman No. 2 filter paper), and the filtrate was concentrated with a rotavapor.

상기 천년초 선인장은 다년초 식물로 선인장(Cactacea)에 속하며 부채선인장아과(Opuntioideae), 부채선인장속(Opuntia)으로 줄기의 형태가 손바닥과 비슷하여 손바닥 선인장으로도 불린다. 폴리페놀 화합물이 함유되어 있어 항산화성이 높으며 무기질, 비타민, 식이섬유, 아미노산, 복합다당류 등 인체에 중요한 영양성분을 함유하고 있다. 오래전부터 선인장의 열매 및 줄기를 변비치료, 이뇨효과, 장운동의 활성화 및 식욕증진의 목적으로 사용하여 왔고, 특히 줄기는 피부질환, 류마티스 및 화상치료에 민간요법으로 사용되고 있다.The cheonnyeoncho cactus is a perennial plant belongs to the cactus (Cactacea), Opuntioideae (Opuntioideae), Opuntia genus (Opuntia) as the shape of the stem is also called palm cactus. It contains high levels of antioxidants and contains important nutrients such as minerals, vitamins, dietary fiber, amino acids, and polysaccharides. The fruit and stem of cactus have been used for a long time for the purpose of constipation treatment, diuretic effect, activation of bowel movement and appetite. Especially, stem is used as folk remedy for skin disease, rheumatism and burn treatment.

상기 천년초 추출물은 동결건조 후 마쇄한 천년초 열매 분말을 물(water)과 1 : 10 ~ 30 중량비가 되도록 첨가한 후, 28 ~ 32 ℃에서 22 ~ 26 시간 동안 추출하여 수득한 용액을 원심분리기를 이용하여 10,000 ~ 13,000 rpm으로 15 ~ 30 분 동안 원심분리한 후, 상등액을 필터로 여과한 여액을 회전증발농축기(Rotavapor)로 농축한 것을 사용한다.The cheonnyeoncho extract is lyophilized after adding the milled cheonnyeoncho fruit powder 1 to 10 to 30 weight ratio with water (water), the solution obtained by extracting for 22 to 26 hours at 28 ~ 32 ℃ using a centrifuge After centrifugation for 15 to 30 minutes at 10,000 ~ 13,000 rpm, the filtrate was filtered with a filter and concentrated using a rotary evaporator (Rotavapor).

더욱 구체적으로는, 동결건조한 천년초 열매를 마쇄하여 분말로 제조한다. 상기 천년초 열매 분말을 물(water)에 첨가하되, 천년초 열매 분말과 물(water)의 혼합비가 1 : 20 중량비가 되도록 첨가한다. 30 ℃에서 24 시간 동안 추출하여 수득한 용액을 원심분리기를 이용하여 12,000 rpm으로 20 분 동안 원심분리한다. 원심분리한 상등액을 필터(Whatman No.2 filter paper)로 여과한 후, 그 여액을 회전증발농축기(Rotavapor)로 농축한다.More specifically, lyophilized cheonnyeoncho fruit is ground to prepare a powder. The cheonnyeoncho fruit powder is added to water, but the mixing ratio of cheonnyeoncho fruit powder and water is added in a 1:20 weight ratio. The solution obtained by extracting at 30 ° C. for 24 hours is centrifuged for 20 minutes at 12,000 rpm using a centrifuge. The centrifuged supernatant is filtered with a filter (Whatman No. 2 filter paper), and the filtrate is concentrated with a rotavapor.

어성초는 삼백초과에 속하는 다년생 초본인 약모빌(Houttuynia cordatathunb)의 잎, 줄기, 꽃, 뿌리를 포함하는 전초이다. 어성초라는 이름은 줄기와 잎에서 물고기 비린내가 난다고 하여 붙여진 명칭이다. 어성초의 성질은 한하고, 맛은 매우며, 폐와 간으로 선택적으로 약효를 작용한다. 약리작용으로는 항균, 항염, 이뇨, 진해작용이 있다.Echoseong is an outpost containing the leaves, stems, flowers, and roots of the perennial herb, Houttuynia cordatathunb. Eoseongcho is named after fishy fishy stems and leaves. The properties of Eoseongcho is limited, the taste is very good, and selectively acts as lung and liver. Pharmacological action is antibacterial, anti-inflammatory, diuretic, antitussive action.

상기 어성초 추출물은 어성초를 에탄올과 1 : 5 ~ 15 중량비로 23 ~ 27 ℃에서 20 ~ 30 시간 동안 침지한 후 상층액과 침전물을 분리하는 일련의 과정을 2 ~ 4 회 반복 추출하여 수득한 용액을 원심분리기를 이용하여 10,000 ~ 13,000 rpm으로 15 ~ 30 분 동안 원심분리한 후, 상등액을 필터로 여과한 여액을 회전증발농축기(Rotavapor)로 농축한 것을 사용한다.The Eochocho extract is obtained by immersing Eochochocho in ethanol with a weight ratio of 1: 5-15 for 20-30 hours at 23-27 ° C. for 20-30 hours, and then extracting the solution obtained by repeating a series of processes 2-4 times to separate the supernatant and the precipitate. After centrifugation at 10,000 to 13,000 rpm for 15 to 30 minutes using a centrifugal separator, the filtrate was filtered with a filter and concentrated using a rotavapor.

더욱 구체적으로는, 어성초를 90 % 에탄올에 첨가하되, 어성초와 90 % 에탄올의 혼합비가 1 : 10 중량비가 되도록 첨가한다. 25 ℃에서 25 시간 동안 침지한 후 상층액과 침전물을 분리한 후, 상기 상층액을 이용하여 동일 과정을 3회 반복한다. 이와 같은 과정을 거쳐 수득한 용액을 원심분리기를 이용하여 12,000 rpm으로 20 분 동안 원심분리한다. 원심분리한 상등액을 필터(Whatman No.2 filter paper)로 여과한 후, 그 여액을 회전증발농축기(Rotavapor)로 농축한다.More specifically, the fish paste is added to 90% ethanol, but the mixing ratio of fish paste and 90% ethanol is added in a 1:10 weight ratio. After immersion at 25 ° C. for 25 hours, the supernatant and the precipitate are separated, and the same process is repeated three times using the supernatant. The solution obtained through this process is centrifuged for 20 minutes at 12,000 rpm using a centrifuge. The centrifuged supernatant is filtered with a filter (Whatman No. 2 filter paper), and the filtrate is concentrated with a rotavapor.

상기 천연보습추출물은 조성물 전체 중량에 대해 0.1 ~ 5.0 wt%의 범위 내로 사용량이 한정되는 것으로서, 그 사용량이 0.1 wt% 미만인 경우에는 보습기능성이 미미하고, 5.0 wt%를 초과하게 되는 경우에는 상대적으로 다른 성분들의 함량이 감소함으로써 박막형성, 항균·항산화, 자외선 차단 등의 기능성이 떨어질 우려가 있으므로, 상기 천연보습추출물의 사용량은 상기 제시된 함량 범위 내로 한정하는 것이 바람직하다.The natural moisturizing extract is limited to the amount used in the range of 0.1 to 5.0 wt% with respect to the total weight of the composition, when the amount is less than 0.1 wt%, the moisturizing function is insignificant, and when the amount exceeds 5.0 wt%, As the content of other components is reduced, there is a possibility that the functionality of thin film formation, antibacterial and antioxidant properties, UV protection, etc. may fall, so the amount of the natural moisturizing extract is preferably limited within the above-mentioned content range.

상기 천연보습추출물은 복령추출물 10 ~ 50 wt%, 수련추출물 10 ~ 50 wt% 및 해삼추출물 10 ~ 50 wt%의 혼합으로 조성된다.The natural moisturizing extract is composed of a mixture of 10 ~ 50 wt% Fukryeong extract, 10 ~ 50 wt% water lily extract and 10 ~ 50 wt% sea cucumber extract.

더욱 구체적으로는, 복령추출물 35 wt%, 수련추출물 35 wt% 및 해삼추출물 30 wt%의 혼합으로 조성된 것을 사용한다.More specifically, 35 wt% of Fuling extracts, 35 wt% of water extracts, and 30 wt% of sea cucumber extracts are used.

복령은 담자균아강 다공균목 구멍장이버섯과에 속하는 버섯의 일종이다. 복령의 주성분으로는 탄수화물, 수분, 조섬유질, 무기질 및 미량의 단백질이 있으며 탄수화물 중 복령다당체(pachyman)가 가장 많고 그 외 pachymic acid, tumulosic acid, dehydrotumulosic acid, ergosterol, eburicoic acid, dehydroeburicoic acid, trametenolic acid 등이 있다.Fukryeong is a type of mushroom belonging to the fungus of the fungus of the subcutaneous fungus subfamily. Carbohydrates contain carbohydrates, water, crude fiber, minerals and trace proteins, and the most carbohydrates are pachyman. Etc.

상기 복령추출물은 분쇄한 복령과 에탄올을 1: 5 ~ 20 중량비로 혼합한 후, 초음파(Sonication) 추출하여 수득한 용액을 필터처리한 후, 그 여액을 회전증발농축기(Rotavapor)로 농축한 것을 사용한다.The Bokryeong extract is a mixture of pulverized Bokryeong and ethanol 1: 5 to 20 by weight ratio, the solution obtained by ultrasonic extraction (Sonication) after the filter process, the filtrate was concentrated using a rotary evaporator (Rotavapor) used do.

더욱 구체적으로는, 분쇄한 복령을 90 % 에탄올에 첨가하되, 분쇄한 복령과 90 % 에탄올의 혼합비가 1 : 10 중량비가 되도록 첨가한다. 30 분간 60 kHz의 초음파을 발생시킨 후 60 시간 동안 실온 상태에서 추출한다. 추출한 용액을 필터(Whatman No.2 filter paper)로 여과한 후, 그 여액을 회전증발농축기(Rotavapor)로 농축한다.More specifically, the pulverized Bokryeong is added to 90% ethanol, but the mixing ratio of the pulverized Bokryeong and 90% ethanol is 1:10 weight ratio. Ultrasound at 60 kHz is generated for 30 minutes and then extracted at room temperature for 60 hours. The extracted solution was filtered with a filter (Whatman No. 2 filter paper), and the filtrate was concentrated with a rotavapor.

수련(Nymphaea tetragona Georgi var.)은 쌍떡잎 식물 미나리아재비목수련과 수련 속 식물이다. 가수분해형 탄닌(Hydrolysable tannin)과 그 구성성분인 geraniin, 1,2,3,4,6-penta-O-galloyl-β-D-glucose(PGG), Ellagic acid 가 분리 되었고, 그 외로도 Amino acids, Alkaroid 이 추가로 보고된 바 있다.The water lily (Nymphaea tetragona Georgi var.) Is a dicotyledonous plant, the genus Amphitaceae, and a genus of water lilies. Hydrolysable tannins and their components, geraniin, 1,2,3,4,6-penta-O-galloyl-β-D-glucose (PGG) and Ellagic acid were isolated. acids, Alkaroid have been reported further.

상기 수련추출물은 수련 줄기와 잎을 동 중량비율로 혼합한 후, 수분함량이 5 wt% 이하가 되도록 63 ~ 68 ℃에서 6 ~ 10 시간 동안 건조하고, 건조한 수련혼합물을 80 % 에탄올과 1 : 5 ~ 20 중량비로 혼합하여 75 ~ 85 ℃의 수욕상에서 2 ~ 4 시간 동안 환류냉각 추출하는 과정을 2 ~ 4 회 반복하여 수득한 용액을 필터처리한 후, 그 여액을 회전증발농축기(Rotavapor)로 농축한 것을 사용한다.The water lily extract was mixed with the water lily stem and leaves in the same weight ratio, and dried for 6 to 10 hours at 63 ~ 68 ℃ so that the moisture content is 5 wt% or less, the dried water mixture is 80% ethanol and 1: 5 After filtering the solution obtained by mixing the mixture at a weight ratio of 20 to 2 to 4 times by reflux cooling extraction for 2 to 4 hours in a water bath of 75 to 85 ℃, the filtrate was concentrated by a Rotavapor (Rotavapor) Use one.

더욱 구체적으로는, 수련 줄기와 잎을 1 : 1 중량비로 혼합하여 혼합물을 조성한다. 상기 혼합물을 65 ℃에서 6 ~ 10 시간 범위 내에서 건조하여 수분함량을 5 wt% 이하로 조절한다. 건조시킨 수련혼합물을 80 % 에탄올에 첨가하되, 상기 수련혼합물과 80 % 에탄올의 혼합비가 1 : 10 중량비가 되도록 첨가한다. 80 ℃의 수욕상에서 3 시간 동안 환류냉각 추출하는 과정을 3회 반복한다. 수득한 용액을 필터(Whatman No.2 filter paper)로 여과한 후, 그 여액을 회전증발농축기(Rotavapor)로 농축한다.More specifically, the water lily stem and leaves are mixed in a 1: 1 weight ratio to form a mixture. The mixture is dried at 65 ° C. in the range of 6-10 hours to adjust the water content to 5 wt% or less. The dried water lily mixture is added to 80% ethanol, but the water lily mixture is added so that the mixing ratio of 80% ethanol is 1:10 weight ratio. The procedure of reflux cooling extraction for 3 hours was repeated three times in an 80 degreeC water bath. The obtained solution was filtered through a filter (Whatman No. 2 filter paper), and the filtrate was concentrated with a rotavapor.

해삼은 극피동물 문의 분류로 해삼강에 속하며 해상, 자삼 및 광삼 등으로 부른다. 해삼은 보습기능 외에, 인체의 단핵세포와 거식세포의 담식 능력을 제고시켜 면역기능을 왕성하게 하고 상처치료에 효과가 있으며, 특히 칼슘과 철분이 충분하여 치아와 골격의 형성, 근육의 정상적 수축과 이완 작용을 조절하는 역할을 한다.Sea cucumber belongs to the sea cucumber river by the classification of echinoderm and is called sea, ginseng and ginseng. In addition to the moisturizing function, sea cucumbers enhance the immune function of mononuclear cells and macrophages in the human body, boosting immune function, and are effective in wound healing. Especially, calcium and iron are sufficient to form teeth and skeleton, and normal contraction of muscles. It plays a role in regulating relaxation.

상기 해삼추출물은 해삼과 에탄올을 1 : 5 ~ 15 중량비율로 혼합한 후, 25 ~ 28 ℃, 20 ~ 30 시간 동안 130 ~ 170 rpm으로 진탕배양기에서 추출한 용액을 원심분리기에서 7,500 ~ 8,500 rpm으로 15 ~ 25 분 동안 원심분리하여 수득한 상층액을 회전증발농축기(Rotavapor)로 농축한 것을 사용한다.The sea cucumber extract is mixed with sea cucumber and ethanol at a weight ratio of 1: 5 to 15, and then the solution extracted from the shaker at 130 to 170 rpm for 25 to 28 ℃, 20 to 30 hours at a 7,500 ~ 8,500 rpm in a centrifuge 15 The supernatant obtained by centrifugation for ˜ 25 minutes is used by concentrating with a Rotavapor.

더욱 구체적으로는, 해삼을 80 % 에탄올에 첨가하되, 상기 해삼과 에탄올의 혼합비가 1 : 10 중량비가 되도록 첨가한다. 진탕배양기에서 26 ℃, 150 rpm 조건으로 25 시간 동안 추출한다. 추출한 용액을 원심분리기를 이용하여 8,000 rpm으로 20 분 동안 원심분리한다. 상층액을 필터(Whatman No.2 filter paper)로 여과한 후, 그 여액을 회전증발농축기(Rotavapor)로 농축한다.More specifically, sea cucumber is added to 80% ethanol, but the mixing ratio of the sea cucumber and ethanol is added in a 1:10 weight ratio. Extracted for 25 hours at 26 ℃, 150 rpm condition in a shaker. The extracted solution is centrifuged at 8,000 rpm for 20 minutes using a centrifuge. After filtering the supernatant with a filter (Whatman No. 2 filter paper), the filtrate is concentrated with a Rotavapor.

상기 천연자외선차단추출물은 조성물 전체 중량에 대해 0.1 ~ 5.0 wt%의 범위 내로 사용량이 한정되는 것으로서, 그 사용량이 0.1 wt% 미만인 경우에는 자외선 차단효과가 미미하고, 5.0 wt%를 초과하게 되는 경우에는 상대적으로 다른 성분들의 함량이 감소함으로써 박막형성, 항균·항산화, 보습 등의 기능성이 떨어질 우려가 있으므로, 상기 천연자외선차단추출물의 사용량은 상기 제시된 함량 범위 내로 한정하는 것이 바람직하다.The amount of natural ultraviolet cut extract is limited to the amount of use in the range of 0.1 to 5.0 wt% with respect to the total weight of the composition, when the amount is less than 0.1 wt%, the sunscreen effect is insignificant, when the amount exceeds 5.0 wt% Since there is a possibility that the functionality of the thin film formation, antibacterial, antioxidant, moisturizing, etc. may be reduced by decreasing the content of other components, the amount of the natural UV-block extract is preferably limited within the above-mentioned content range.

상기 천연자외선차단추출물은 고삼 10 ~ 35 wt%와, 구척 10 ~ 35 wt%와, 대황 10 ~ 35 wt%와, 비자 10 ~ 35 wt%를 혼합한 후 마쇄하고, 마쇄한 혼합물을 90 % 메탄올과 1 : 5 ~ 20 중량비로 혼합하여 20 ~ 30 ℃, 150 ~ 300 rpm으로 5 ~ 60 시간 동안 진탕 추출하고, 추출하여 수득한 용액을 필터를 이용하여 여과한 여액을 회전증발농축기(Rotavapor)로 농축한 것을 사용한다.The natural UV cut extract was ground and mixed with 10 ~ 35 wt% Gosam, 10 ~ 35 wt% Gukje, 10 ~ 35 wt% rhubarb, 10 ~ 35 wt% Visa, and the ground mixture 90% methanol And 1: 5 to 20 by weight ratio, the mixture was shaken at 20 to 30 ℃, 150 to 300 rpm for 5 to 60 hours, and the filtrate was filtered using a filter and the filtrate was filtered using a rotavapor. Use concentrated ones.

더욱 구체적으로는, 고삼 25 wt%와, 구척 25 wt%와, 대황 25 wt%와, 비자 25 wt%를 혼합하여 한약혼합물을 조성한 후 마쇄한다. 마쇄한 한약혼합물을 90 % 메탄올에 첨가하되, 상기 마쇄한 한약혼합물과 90 % 메탄올의 혼합비가 1 : 10 중량비가 되도록 혼합한다. 진탕배양기에서 26 ℃, 200 rpm 조건으로 50 시간 동안 추출한다. 추출한 용액을 필터(Whatman No.2 filter paper)로 여과한 후, 그 여액을 회전증발농축기(Rotavapor)로 농축한다.More specifically, 25% by weight of red ginseng, 25% by weight of red ginseng, 25% by weight of rhubarb, and 25% by weight of bismuth are mixed to form a herbal mixture and then ground. The ground herbal mixture is added to 90% methanol, but the mixture of the ground herbal mixture and 90% methanol is mixed in a 1:10 weight ratio. Extracted in shake incubator at 26 ℃, 200 rpm for 50 hours. The extracted solution was filtered with a filter (Whatman No. 2 filter paper), and the filtrate was concentrated with a rotavapor.

상기 문신 부위 감염방지용 코팅 조성물의 구체적인 배합비는 다음의 표 1과 같다.Specific mixing ratio of the coating composition for preventing infection of the tattoo site is shown in Table 1 below.

성분ingredient 실시예 1Example 1 실시예 2Example 2 실시예 3Example 3 실시예 4Example 4 실시예 5Example 5 정제수(Water)Purified Water 89.089.0 91.091.0 90.090.0 91.091.0 89.089.0 폴리비닐알코올(Polyvinyl alcohol)Polyvinyl alcohol
5.8

5.8

4.2

4.2

4.0

4.0

3.0

3.0

3.0

3.0
디메치콘(Dimethicone)Dimethicone
1.0

1.0

1.0

1.0

2.0

2.0

1.0

1.0

1.0

1.0
에틸헥실글리세린(Ethylhexylglycerin)Ethylhexylglycerin
2.0

2.0

1.7

1.7

1.6

1.6

1.2

1.2

0.4

0.4
1,2-헥산다이올(1,2-Hexanediol)1,2-hexanediol (1,2-Hexanediol)
1.5

1.5

1.0

1.0

1.5

1.5

1.0

1.0

0.5

0.5
하이드록시에틸셀룰로스Hydroxyethylcellulose
0.1

0.1

0.2

0.2

0.2

0.2

0.4

0.4

0.1

0.1
천연항산화·항균추출물1) Natural antioxidant and antibacterial extract 1)
0.2

0.2

0.3

0.3

0.2

0.2

0.8

0.8

2.0

2.0
천연보습추출물2) Natural Moisturizing Extract 2)
0.2

0.2

0.3

0.3

0.2

0.2

0.8

0.8

2.0

2.0
천연자외선차단추출물3) Natural Ultraviolet Block 3)
0.2

0.2

0.3

0.3

0.3

0.3

0.8

0.8

2.0

2.0

상기 표 1에서,In Table 1 above,

1) 천연항산화·항균추출물은 산수유 추출물 50 wt%, 천년초 추출물 25 wt% 및 어성초 추출물 25 wt%의 혼합물로부터 추출된 추출물이다.1) Natural antioxidant and antibacterial extract is an extract extracted from a mixture of 50 wt% cornus extract, 25 wt% cheonnyeoncho extract, and 25 wt% fish extract.

2) 천연보습추출물은 복령추출물 35 wt%, 수련추출물 35 wt% 및 해삼추출물 30 wt%의 혼합물로부터 추출된 추출물이다.2) The natural moisturizing extract is an extract extracted from a mixture of 35 wt% of Fuling extract, 35 wt% of water lily extract and 30 wt% of sea cucumber extract.

3) 천연자외선차단추출물은 고삼 25 wt%와, 구척 25 wt%와, 대황 25 wt%와, 비자 25 wt%의 혼합물로부터 추출된 추출물이다.3) The natural UV-block extract is an extract extracted from a mixture of 25 wt% of red ginseng, 25 wt% of ginseng, 25 wt% of rhubarb, and 25 wt% of non-visible.

상기 제시된 기술 구성 외에,In addition to the technical configuration presented above,

문신 부위 감염방지용 코팅 조성물은 문신 시술 후 피부 진정효과를 부여하기 위하여 천연피부진정용조성물을 더 부가하여 조성할 수 있다.Tattoo site infection prevention coating composition may be further added to the natural skin soothing composition in order to give the skin soothing effect after the tattoo procedure.

더욱 상세하게는, More specifically,

병풀(Centella asiatica) 추출물 10 ~ 50 wt%와, 10-50 wt% Centella asiatica extract,

상추 추출물 10 ~ 50 wt%와,Lettuce extract with 10-50 wt%,

스피루리나 추출물 10 ~ 50 wt%의 혼합으로 조성된 100 wt%의 천연피부진정용조성물(j) 0.1 ~ 5.0 wt%를 더 포함하여 조성한다.Spirulina extract is composed of a mixture of 10 to 50 wt% of 100 wt% of the natural skin soothing composition (j) further comprises 0.1 to 5.0 wt%.

상기 천연피부진정용조성물(j)의 구체적인 예로는, 병풀(Centella asiatica) 추출물 30 wt%, 상추 추출물 40 wt%, 스피루리나 추출물 30 wt%의 혼합으로 조성된 것을 사용한다.As a specific example of the natural skin soothing composition (j), Centella asiatica extract 30 wt%, lettuce extract 40 wt%, spirulina extract using a mixture of 30 wt%.

상기 병풀(Centella asiatica)은 산형과에 속하는 다년생 포복성 초본이다. 병풀, 적설초, 호랑이풀로 불리며 물속이나 물삭에서 잘자라는 무미, 무취의 식풀이다. 병풀의 주성분으로서 a-amyrin-ursolic acid group에 속하는 pentacyclic triterpene glycoside인 asiaticoside와 madecasso-side는 오래 전부터 피부 상처나 만성궤양 등의 치료에 사용되어 왔다. 피부조직의 재생력을 갖는 약물로 콜라겐 생성을 촉진시키는 것으로 알려져 있다.Centella asiatica is a perennial crawling herb belonging to the antacid family. Called centella, red snow, tiger grass, it is a tasteless and odorless plant that grows well in water or water. Asiaticoside and madecasso-side, pentacyclic triterpene glycosides belonging to the a-amyrin-ursolic acid group, have been used for the treatment of skin wounds and chronic ulcers for a long time. It is known to promote collagen production as a drug having regeneration of skin tissue.

상기 병풀(Centella asiatica) 추출물은 분쇄한 병풀을 70 % 에탄올에 첨가하되, 상기 병풀과 70 % 에탄올의 배합비가 1 : 5 ~ 15 중량비가 되도록 첨가하여 23 ~ 25 ℃에서 20 ~ 30 시간 동안 침지한 후 상등액과 침전물을 분리하고, 동일 과정을 2 ~ 4 회 반복 수행한 후, 수득한 용액을 여과지(Whatman No.2)를 이용하여 여과하고, 여액을 회전증발농축기(Rotavapor)로 농축하여 제조한다.The Centella asiatica extract is added to the pulverized centellae to 70% ethanol, the mixture ratio of the centellae and 70% ethanol is 1: 5 to 15 by weight added soaked for 20 to 30 hours at 23 ~ 25 ℃ After separating the supernatant and the precipitate, the same process is repeated 2 to 4 times, the resulting solution is filtered using a filter paper (Whatman No. 2), and the filtrate is prepared by concentrating with a rotary evaporator (Rotavapor). .

더욱 구체적으로는, 분쇄한 병풀을 10 배 중량의 70 % 에탄올에 침지하여 24시간 동안 경과 후 상등액과 침전물을 분리한다. 동일 과정을 3회 반복한다.More specifically, the pulverized centella is immersed in 10-fold 70% ethanol to separate the supernatant and the precipitate after 24 hours. Repeat the same process three times.

추출된 용액 모두 합하여 여과지(Whatman No.2)로 여과한 후 회전증발농축기(Rotavapor)로 농축하여 병풀(Centella asiatica) 추출물을 제조한다.All the extracted solutions were combined and filtered with a filter paper (Whatman No. 2), and then concentrated on a rotavapor to prepare Centella asiatica extract.

상기 상추 추출물은 분쇄한 상추와 에탄올을 1: 5 ~ 20 중량비로 혼합한 후, 초음파(Sonication) 추출하여 수득한 용액을 필터처리한 후, 그 여액을 회전증발농축기(Rotavapor)로 농축하여 제조한다.The lettuce extract is prepared by mixing crushed lettuce and ethanol in a weight ratio of 1: 5 to 20, and then filtering the solution obtained by sonication extraction, and then concentrating the filtrate with a rotary evaporator. .

더욱 구체적으로는, 분쇄한 상추를 80 % 에탄올에 첨가하되, 분쇄한 상추와 80 % 에탄올의 혼합비가 1 : 10 중량비가 되도록 첨가한다. 25 분간 60 kHz의 초음파을 발생시킨 후 55 시간 동안 실온 상태에서 추출한다. 추출한 용액을 필터(Whatman No.2)로 여과한 후, 그 여액을 회전증발농축기(Rotavapor)로 농축한다.More specifically, the crushed lettuce is added to 80% ethanol, but the mixing ratio of the crushed lettuce and 80% ethanol is added in a 1:10 weight ratio. Ultrasound at 60 kHz is generated for 25 minutes and then extracted at room temperature for 55 hours. The extracted solution is filtered with a filter (Whatman No. 2), and the filtrate is concentrated with a rotavapor.

상기 스피루리나(Spirulina platensis)는 지구상에서 가장 오래된 조류(algae)의 하나로 약 35억년 전에 탄생한 최초의 광합성 생명체이다. 구성성분으로는 60 ~ 70 %의 단백질, 6 ~ 9 %의 지질, 15 ~ 20 %의 탄수화물 및 다량의 비타민, 무기질, 섬유질을 함유하고 있다.The Spirulina platensis is one of the oldest algae on the planet and was the first photosynthetic organism born about 3.5 billion years ago. The constituents contain 60-70% protein, 6-9% lipids, 15-20% carbohydrates and large amounts of vitamins, minerals and fiber.

상기 스피루리나 추출물은 스피루리나와 증류수 1 : 40 ~ 50 중량비로 혼합한 혼합물을 25 ~ 28 ℃, 60 ~ 65 시간 동안 100 ~ 150 rpm으로 진탕배양기에서 추출하고, 추출한 용액을 원심분리에서 7,000 ~ 8,000 rpm으로 10 ~ 20 분 동안 원심분리하여 수득한 상층액을 필터페이퍼(Whatman No.2)로 여과하고, 여과한 여액을 회전증발농축기(Rotavapor)로 농축하여 제조한다.The spirulina extract is a mixture of spirulina and distilled water 1:40 to 50 weight ratio extracted at a shaker incubator at 100 to 150 rpm for 25 to 28 ℃, 60 to 65 hours, the extracted solution at 7,000 to 8,000 rpm in centrifugation The supernatant obtained by centrifugation for 10 to 20 minutes is filtered through a filter paper (Whatman No. 2), and the filtrate is concentrated by concentration in a rotavapor.

더욱 구체적으로는, 스피루리나와 증류수 1 : 50 중량비로 혼합한 혼합물을 26 ℃, 63 시간 동안 130 rpm으로 진탕배양기에서 추출하고, 추출한 용액을 원심분리에서 7,500 rpm으로 15 분 동안 원심분리하여 수득한 상층액을 필터페이퍼(Whatman No.2)로 여과하고, 여과한 여액을 회전증발농축기(Rotavapor)로 농축하여 스피루리나 추출물을 제조한다.More specifically, the upper layer obtained by extracting a mixture of spirulina and distilled water 1:50 weight ratio in a shake incubator at 130 rpm for 26 hours, 63 ℃, and centrifugation for 15 minutes at 7,500 rpm by centrifugation The liquid is filtered through filter paper (Whatman No. 2), and the filtrate is concentrated with a rotary evaporator (Rotavapor) to prepare an spirulina extract.

상기 제시된 성분 외에,In addition to the components set forth above,

문신 부위 감염방지용 코팅 조성물의 보존 및 사용기간을 연장하기 위한 자몽씨 추출물, 피부노화방지 기능을 갖는 천마 추출물, 보습 기능을 갖는 황금 추출물을 더 포함하여 기능성을 더욱 높일 수 있다.Grapefruit seed extract for extending the preservation and use of the coating composition for preventing infection of the tattoo site, cheonma extract having an anti-aging function, golden extract having a moisturizing function can be further enhanced.

상기 자몽씨 추출물은 자몽씨추출물은 아스코르빈산, palmitic acid, 글루코오즈, 나린진, 토코페롤 등을 포함하고 있는 천연 항균물질로서 본 발명에서는 보존료로서 사용된다.The grapefruit seed extract is a grapefruit seed extract is a natural antibacterial substance containing ascorbic acid, palmitic acid, glucose, naringin, tocopherol and the like is used as a preservative in the present invention.

상기 자몽씨 추출물은 자몽씨와 에탄올을 1 : 10 ~ 20 중량비로 혼합한 후, 55 ~ 60 ℃의 온도 조건에서 3 ~ 5 시간 동안 환류냉각시킨 다음 10,000×g에서 20 ~ 40 분간 원심분리하고, 상등액을 여과한 여액을 회전증발농축기(Rotavapor)로 농축하여 제조한다.The grapefruit seed extract is mixed with grapefruit seed and ethanol in a weight ratio of 1: 10 to 20, and reflux-cooled for 3 to 5 hours at a temperature condition of 55 to 60 ℃, then centrifuged at 10,000 × g for 20 to 40 minutes, The filtrate, after filtering the supernatant, is prepared by concentrating with a Rotavapor.

상기 자몽씨 추출물은 감염방지용 코팅조성물의 전체 중량에 대해 0.1 ~ 3.0 wt%의 범위 내에서 사용되며, 이때 첨가량이 0.1 wt% 미만인 경우에는 자몽씨 추출물에 의한 보존기능성을 향상을 기대하기 어렵고, 3.0 wt%를 초과하게 되는 경우에는 필요 이상의 사용으로 인해 무의미하므로 상기 자몽씨 추출물의 사용량은 감염방지용 코팅조성물의 전체 중량에 대해 0.1 ~ 3.0 wt%의 범위 내에서 한정하는 것이 바람직하다.The grapefruit seed extract is used within the range of 0.1 to 3.0 wt% with respect to the total weight of the coating composition for preventing infection, and when the addition amount is less than 0.1 wt%, it is difficult to expect to improve the storage functionality by the grapefruit seed extract, 3.0 When the amount exceeds wt%, the use of the grapefruit seed extract is meaningless due to the use more than necessary. It is preferable to limit the amount of the grapefruit seed extract within the range of 0.1 to 3.0 wt% based on the total weight of the coating composition for preventing infection.

상기 천마는 오랜 기간 동양의학의 약재로 사용되어왔던 것으로서, 스트레스나 피로 뿐 아니라 두통, 중풍, 뇌신경쇠약증, 고혈압, 당뇨병 등의 잘환에 효과가 있는 것으로 알려져 있다. 천마추출물은 항산화활성과 콜라겐 분해저해물질에 의한 주름개선효과를 통해 피부노화방지의 기능을 갖는다.The cheonma has been used as a medicine of oriental medicine for a long time, and is known to be effective in well-illusion such as headache, stroke, cranial nerve weakness, hypertension, diabetes, as well as stress and fatigue. Chunma extract has the function of preventing skin aging through anti-wrinkle effect by antioxidant activity and collagen degradation inhibitors.

상기 천마 추출물은 천마와 증류수를 1 : 10 ~ 20 중량비로 혼합한 후 환류추출기를 이용하여 90 ~ 95 ℃에서 3 ~ 6 시간 동안 추출하고, 추출액을 3,000 ~ 4,000 rpm에서 3 ~ 10분 동안 원심분리하고, 상등액을 여과한 여액을 회전증발농축기(Rotavapor)로 농축하여 제조한다.The cheonma extract is mixed with cheonma and distilled water in a weight ratio of 1: 10 ~ 20, and extracted for 3 to 6 hours at 90 ~ 95 ℃ using a reflux extractor, centrifuged for 3 to 10 minutes at 3,000 ~ 4,000 rpm In addition, the filtrate obtained by filtering the supernatant is prepared by concentrating with a rotary evaporator (Rotavapor).

상기 천마추출물은 감염방지용 코팅조성물의 전체 중량에 대해 0.1 ~ 3.0 wt%의 범위 내에서 사용되며, 이때 첨가량이 0.1 wt% 미만인 경우에는 천마추출물에 의한 피부노화방지 기능이 미미하고, 3.0 wt%를 초과하게 되는 경우에는 피부노화방지 효과의 개선이 미미하여 무의미하므로, 상기 천마추출물의 사용량은 감염방지용 코팅조성물의 전체 중량에 대해 0.1 ~ 3.0 wt%의 범위 내에서 한정하는 것이 바람직하다.The cheonma extract is used within the range of 0.1 to 3.0 wt% with respect to the total weight of the coating composition for preventing infection, and when the amount is less than 0.1 wt%, the skin aging prevention function by the cheonma extract is insignificant, 3.0 wt% If it exceeds, the improvement of the skin anti-aging effect is insignificant and meaningless, it is preferable to limit the amount of the cheonma extract used within the range of 0.1 to 3.0 wt% based on the total weight of the coating composition for preventing infection.

그리고 상기 황금 추출물은 감염방지용 코팅조성물을 구성하는 천연보습추출물에 보습 기능을 보조하기 위한 보습보조제로 사용되는 것으로서, 황금과 메탄올을 1 : 5 ~ 10 중량비로 혼합한 혼합물을 60 ~ 70℃에서 10 ~ 20 시간 동안 환류추출하고, 추출물을 3,000 ~ 5,00 rpm에서 5 ~ 10분 동안 원심분리하고, 상등액을 여과한 여액을 회전증발농축기(Rotavapor)로 농축하여 제조한다.And the golden extract is to be used as a moisturizing aid to assist the moisturizing function in the natural moisturizing extract constituting the coating composition for preventing infection, a mixture of gold and methanol in a weight ratio of 1: 5 to 10 10 at 60 ~ 70 ℃ 10 The mixture is refluxed for 20 hours, the extract is centrifuged at 3,000 to 5,00 rpm for 5 to 10 minutes, and the filtrate, after filtering the supernatant, is prepared by concentrating with a rotary evaporator (Rotavapor).

상기 황금추출물은 감염방지용 코팅조성물의 전체 중량에 대해 0.1 ~ 3.0 wt%의 범위 내에서 사용되며, 이때 첨가량이 0.1 wt% 미만인 경우에는 황금추출물에 의한 보습 기능 향상을 기대하기 어렵고, 3.0 wt%를 초과하게 되는 경우에는 보습 기능 향상을 위한 보조제로서 초과사용되어 무의미하므로, 상기 황금추출물의 사용량은 감염방지용 코팅조성물의 전체 중량에 대해 0.1 ~ 3.0 wt%의 범위 내에서 한정하는 것이 바람직하다.The golden extract is used within the range of 0.1 to 3.0 wt% with respect to the total weight of the coating composition for preventing infection, and when the addition amount is less than 0.1 wt%, it is difficult to expect to improve the moisturizing function by the golden extract, 3.0 wt% In case of exceeding, the use of the golden extract is insignificant because it is meaningless as an auxiliary agent for improving the moisturizing function, and it is preferable to limit the amount of the golden extract within the range of 0.1 to 3.0 wt% based on the total weight of the coating composition for preventing infection.

상기 제조공정을 거쳐 제조된 감염방지용 코팅조성물은 종래 분무식 제품에 많이 사용되고 있는 디메틸 에테르 등의 액화가스와 함께 용기에 충진함으로써 분사방식에 의해 문신 부위에 뿌려줌으로서 필름 박막을 형성되도록 한다.The coating composition for preventing infection prepared through the above manufacturing process is filled into a container together with a liquefied gas such as dimethyl ether, which is widely used in conventional spray products, so that a film thin film is formed by spraying on a tattoo part by a spraying method.

본 발명에 따른 문신 부위 감염방지용 코팅 조성물은 문신 시술 후 문신 부위를 중심으로 스프레이 방식으로 간편하게 뿌려줌으로써 문신 부위에 필름 박막이 형성되어 세균이 문신 부위를 통해 인체로 침투하는 것을 차단하여 세균감염 예방효과가 뛰어나고, 자체 항산화·항균 기능에 의해 피부의 노화, 피부 오염의 억제효과를 가지며, 피부보습 및 자외선 차단 기능에 의한 피부 건강상태를 향상시키는 효과를 가짐으로써 산업상 이용가능성이 크다.The coating composition for preventing infection of the tattoo site according to the present invention is sprayed around the tattoo area by a spray method after the tattoo treatment, and a film thin film is formed on the tattoo site to prevent bacteria from penetrating into the human body through the tattoo site, thereby preventing bacterial infection. It has an excellent anti-oxidation and antibacterial function, and has an effect of inhibiting skin aging and skin contamination, and having an effect of improving skin health condition by skin moisturizing and UV blocking function, and thus is highly industrially applicable.

Claims (7)

정제수(Water)(a) 90.0 wt%;
폴리비닐알코올(Polyvinyl alcohol)(b) 4.0 wt%;
디메치콘(Dimethicone)(c) 2.0 wt%;
에틸헥실글리세린(Ethylhexylglycerin)(d) 1.6 wt%;
1,2-헥산다이올(1,2-Hexanediol)(e) 1.5 wt%;
하이드록시에틸셀룰로스의 점증제(f) 0.2 wt%;
건조시킨 산수유 열매와 잎을 동중량비율로 혼합하여 혼합물을 조성하고, 상기 혼합물을 20 ~ 50 배의 증류수에 첨가한 후 35 ~ 39 ℃에서 150 ~ 300 rpm으로 1 ~ 48 시간 동안 진탕 추출하고, 추출하여 수득한 용액을 필터를 이용하여 여과한 여액을 회전증발농축기(Rotavapor)로 농축하여 제조된 산수유 추출물 50.0 wt%와,
동결건조 후 마쇄한 천년초 열매 분말을 물(water)과 1 : 10 ~ 30 중량비가 되도록 첨가한 후, 28 ~ 32 ℃에서 22 ~ 26 시간 동안 추출하여 수득한 용액을 원심분리기를 이용하여 10,000 ~ 13,000 rpm으로 15 ~ 30 분 동안 원심분리한 후, 상등액을 필터로 여과한 여액을 회전증발농축기(Rotavapor)로 농축하여 제조된 천년초 추출물 25.0 wt%과,
어성초를 에탄올과 1 : 5 ~ 15 중량비로 23 ~ 27 ℃에서 20 ~ 30 시간 동안 침지한 후 상층액과 침전물을 분리하는 일련의 과정을 2 ~ 4 회 반복 추출하여 수득한 용액을 원심분리기를 이용하여 10,000 ~ 13,000 rpm으로 15 ~ 30 분 동안 원심분리한 후, 상등액을 필터로 여과한 여액을 회전증발농축기(Rotavapor)로 농축하여 제조된 어성초 추출물 25.0 wt%로 구성된 100 wt%의 천연항산화·항균추출물(g) 0.2 wt%;
분쇄한 복령과 에탄올을 1: 5 ~ 20 중량비로 혼합한 후, 초음파(Sonication) 추출하여 수득한 용액을 필터처리한 후, 그 여액을 회전증발농축기(Rotavapor)로 농축하여 제조된 복령추출물 35.0 wt%와,
수련 줄기와 잎을 동 중량비율로 혼합한 후, 수분함량이 5 wt% 이하가 되도록 63 ~ 68 ℃에서 6 ~ 10 시간 동안 건조하고, 건조한 수련혼합물을 80 % 에탄올과 1 : 5 ~ 20 중량비로 혼합하여 75 ~ 85 ℃의 수욕상에서 2 ~ 4 시간 동안 환류냉각 추출하는 과정을 2 ~ 4 회 반복하여 수득한 용액을 필터처리한 후, 그 여액을 회전증발농축기(Rotavapor)로 농축하여 제조된 수련추출물 35.0 wt%와,
해삼과 에탄올을 1 : 5 ~ 15 중량비율로 혼합한 후, 25 ~ 28 ℃, 20 ~ 30 시간 동안 130 ~ 170 rpm으로 진탕배양기에서 추출한 용액을 원심분리기에서 7,500 ~ 8,500 rpm으로 15 ~ 25 분 동안 원심분리하여 수득한 상층액을 회전증발농축기(Rotavapor)로 농축하여 제조된 해삼추출물 30.0 wt%의 혼합으로 조성된 100 wt%의 천연보습추출물(h) 0.2 wt%;
고삼 25.0 wt%와, 구척 25.0 wt%와, 대황 25.0 wt%와, 비자 25.0 wt%를 혼합한 후 마쇄하고, 마쇄한 혼합물을 90 % 메탄올과 1 : 5 ~ 20 중량비로 혼합하여 20 ~ 30 ℃, 150 ~ 300 rpm으로 5 ~ 60 시간 동안 진탕 추출하고, 추출하여 수득한 용액을 필터를 이용하여 여과한 여액을 회전증발농축기(Rotavapor)로 농축하여 제조된 천연자외선차단추출물(i) 0.3 wt%;의 혼합(a+b+c+d+e+f+g+h+i)으로 구성되어, 문신부위에 스프레이 방식으로 뿌려 필름 박막을 형성하는 것을 특징으로 하는 문신 부위 감염방지용 코팅 조성물.

Purified water (a) 90.0 wt%;
Polyvinyl alcohol (b) 4.0 wt%;
Dimethicone (c) 2.0 wt%;
Ethyl hexylglycerin (d) 1.6 wt%;
1,2-hexanediol (1,2-Hexanediol) (e) 1.5 wt%;
0.2 wt% of a thickener (f) of hydroxyethylcellulose;
The dried cornus fruit and leaves were mixed at the same weight ratio to form a mixture, and the mixture was added to 20 to 50 times distilled water, followed by shaking extraction at 150 to 300 rpm at 35 to 39 ° C. for 1 to 48 hours. 50.0 wt% of a cornus extract, prepared by concentrating the filtrate obtained by extraction using a filter and concentrating with a rotavapor;
After freeze-drying, the milled cheonnyeoncho fruit powder was added with water (water) in a ratio of 1: 10 to 30, and then the solution obtained by extracting at 28 to 32 ° C. for 22 to 26 hours using a centrifuge was used at 10,000 to 13,000. After centrifugation for 15 to 30 minutes at rpm, the filtrate filtered with the filter supernatant 25.0 wt% of cheonnyeoncho extract prepared by concentrating with a rotary evaporator (Rotavapor),
The solution obtained by immersing Echoseongcho and ethanol at 1: 5 to 15 weight ratio for 20 to 30 hours at 23 to 27 ℃ for 20 to 30 hours and then repeatedly extracting a series of processes of separating supernatant and precipitate 2 to 4 times using a centrifuge After centrifugation at 10,000 to 13,000 rpm for 15 to 30 minutes, the supernatant was filtered using a filter, and the filtrate was concentrated using a rotavapor. Extract (g) 0.2 wt%;
After mixing pulverized Bokryeong and ethanol in a weight ratio of 1: 5 to 20, and filtering the solution obtained by sonication extraction, the filtrate was concentrated by a rotary evaporator (Rotavapor) 35.0 wt. %Wow,
After mixing the water lily stem and the leaves at the same weight ratio, the water content was dried at 63 ~ 68 ℃ for 6 to 10 hours so that the water content is 5 wt% or less, and the dried water lily mixture with 80% ethanol and 1: 5 to 20 weight ratio After mixing and filtering the solution obtained by repeating the reflux cooling extraction for 2 to 4 hours in a water bath at 75 to 85 ° C. for 2 to 4 times, the filtrate was concentrated by a rotary evaporator. With 35.0 wt% extract,
After mixing sea cucumber and ethanol at a weight ratio of 1: 5 to 15, the solution extracted from the shaker at 130 to 170 rpm for 25 to 28 ° C. and 20 to 30 hours for 15 to 25 minutes at 7,500 to 8,500 rpm in a centrifuge 0.2 wt% of 100 wt% natural moisturizing extract (h) composed of a mixture of 30.0 wt% of sea cucumber extract prepared by concentrating the supernatant obtained by centrifugation with a rotavapor;
25.0 wt% of red ginseng, 25.0 wt% of ginseng, 25.0 wt% of rhubarb, and 25.0 wt% of biscuit, and then ground. The ground mixture was mixed with 90% methanol in a 1: 5 to 20 weight ratio to 20 to 30 ° C , Natural extract of ultraviolet ray extract (i) prepared by shaking the extract for 5 to 60 hours at 150 to 300 rpm and concentrating the filtrate filtered using a filter with a rotavapor. It consists of a mixture of (a + b + c + d + e + f + g + h + i), spray coating on the tattoo portion to form a film thin film, characterized in that the infection prevention tattoo composition.

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KR1020180005486A 2018-01-16 2018-01-16 Coating composition for infection control of tattoo area and method of preparing the same KR102012000B1 (en)

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KR102662693B1 (en) 2022-02-15 2024-04-30 추교익 Method for manufacturing tattoo care balm and tattoo care balm manufactured through same
BR102022007409A2 (en) * 2022-04-18 2023-10-31 Mboah Cosméticos Ltda SUSTAINABLE PROTECTIVE FILM FOR TATTOOED SKIN

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KR20030092519A (en) * 2002-05-30 2003-12-06 주식회사 리젠 바이오텍 Composition for improving or preventing of allergic dermatological diseases
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