KR101087608B1 - 갱년기 또는 폐경기 증상의 예방 또는 완화용 식물성에스트로겐 조성물 - Google Patents
갱년기 또는 폐경기 증상의 예방 또는 완화용 식물성에스트로겐 조성물 Download PDFInfo
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- KR101087608B1 KR101087608B1 KR1020090032821A KR20090032821A KR101087608B1 KR 101087608 B1 KR101087608 B1 KR 101087608B1 KR 1020090032821 A KR1020090032821 A KR 1020090032821A KR 20090032821 A KR20090032821 A KR 20090032821A KR 101087608 B1 KR101087608 B1 KR 101087608B1
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- extract
- estrogen
- present
- composition
- menopausal
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8967—Lilium, e.g. tiger lily or Easter lily
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/234—Cnidium (snowparsley)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/306—Foods, ingredients or supplements having a functional effect on health having an effect on bone mass, e.g. osteoporosis prevention
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- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/322—Foods, ingredients or supplements having a functional effect on health having an effect on the health of the nervous system or on mental function
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Abstract
Description
실험군 | 에스트라디올 (E2, 9x10-9 M) |
백합 추출물 (0.0625 ㎍/mL) |
백합 추출물 (0.25 ㎍/mL) |
백합 추출물 (1 ㎍/mL) |
백합 추출물 (4 ㎍/mL) |
REA(%) 평균 | 100 | -3.43 | 5.48 | 21.39 | 40.26 |
표준편차 | 7.43 | 2.47 | 2.28 | 1.95 | 2.36 |
실험군 | 에스트라디올 (E2, 9x10-9 M) |
벌사상자 추출물 (0.0625 ㎍/mL) |
벌사상자 추출물 (0.25 ㎍/mL) |
벌사상자 추출물 (1 ㎍/mL) |
벌사상자 추출물 (4 ㎍/mL) |
REA(%) 평균 | 100 | 29.44 | 32.08 | 39.77 | 34.52 |
표준편차 | 7.43 | 4.57 | 8.56 | 41.65 | 1.32 |
실험군 | 에스트라디올 (E2, 9x10-9 M) |
원지 추출물 (0.0625 ㎍/mL) |
원지 추출물 (0.25 ㎍/mL) |
원지 추출물 (1 ㎍/mL) |
원지 추출물 (4 ㎍/mL) |
REA(%) 평균 | 100 | -31.35 | 7.20 | 38.28 | 49.9 |
표준편차 | 7.43 | 16.27 | 0.41 | 1.59 | 12.01 |
실험군 | 에스트라디올 (E2, 9x10-9 M) |
상백피 추출물 (0.0625 ㎍/mL) |
상백피 추출물 (0.25 ㎍/mL) |
상백피 추출물 (1 ㎍/mL) |
상백피 추출물 (4 ㎍/mL) |
REA(%) 평균 | 100 | -18.88 | 8.52 | 36.44 | 44.69 |
표준편차 | 7.43 | 3.64 | 6.52 | 1.66 | 5.52 |
실험군 | 4-히드록시 타목시펜 (0.4 ㎍/mL) |
백합 추출물 (0.0625 ㎍/mL) |
백합 추출물 (0.25 ㎍/mL) |
백합 추출물 (1 ㎍/mL) |
백합 추출물 (4 ㎍/mL) |
저해율(%) | 55.78 | 106.6 | 107.99 | 103.37 | 103.83 |
표준편차 | 3.34 | 7.23 | 2.06 | 4.20 | 28.86 |
실험군 | 4-히드록시 타목시펜 (0.4 ㎍/mL) |
벌사상자 추출물 (0.0625 ㎍/mL) |
벌사상자 추출물 (0.25 ㎍/mL) |
벌사상자 추출물 (1 ㎍/mL) |
벌사상자 추출물 (4 ㎍/mL) |
저해율(%) | 55.78 | 56.83 | 62.28 | 68.38 | 83.77 |
표준편차 | 3.34 | 2.31 | 1.83 | 7.14 | 1.02 |
실험군 | 4-히드록시 타목시펜 (0.4 ㎍/mL) |
원지 추출물 (0.0625 ㎍/mL) |
원지 추출물 (0.25 ㎍/mL) |
원지 추출물 (1 ㎍/mL) |
원지 추출물 (4 ㎍/mL) |
저해율(%) | 55.78 | 109.77 | 85.41 | 81.78 | 57.82 |
표준편차 | 3.34 | 1.73 | 0.34 | 0.50 | 13.55 |
실험군 | 4-히드록시 타목시펜 (0.4 ㎍/mL) |
상백피 추출물 (0.0625 ㎍/mL) |
상백피 추출물 (0.25 ㎍/mL) |
상백피 추출물 (1 ㎍/mL) |
상백피 추출물 (4 ㎍/mL) |
저해율(%) | 55.78 | 81.78 | 103.89 | 102.24 | 104.75 |
표준편차 | 3.34 | 2.89 | 6.93 | 7.21 | 1.98 |
Claims (6)
- 백합(Lilium longiflorum) 추출물을 유효성분으로 포함하는 갱년기 또는 폐경기 증상의 예방 또는 완화용 식물성에스트로겐 조성물.
- 삭제
- 제 1 항에 있어서, 상기 갱년기 또는 폐경기 증상은 안면홍조, 발한, 피부 건조, 질 건조증, 질 위축, 하부 요도 위축, 성교 통, 질염, 방광염, 배뇨통, 급뇨, 집중장애, 단기 기억장애, 불안, 신경과민, 기억력 감소, 성욕 감퇴, 근육통, 관절통 또는 골다공증인 것을 특징으로 하는 갱년기 또는 폐경기 증상의 예방 또는 완화용 식물성에스트로겐 조성물.
- 백합(Lilium longiflorum) 추출물을 유효성분으로 포함하는 에스트로겐-의존성 질환의 예방 또는 완화용 식물성에스트로겐 조성물.
- 삭제
- 제 4 항에 있어서, 상기 에스트로겐-의존성 질환은 유방암 또는 자궁암인 것을 특징으로 하는 에스트로겐-의존성 질환의 예방 또는 완화용 식물성에스트로겐 조성물.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020090032821A KR101087608B1 (ko) | 2009-04-15 | 2009-04-15 | 갱년기 또는 폐경기 증상의 예방 또는 완화용 식물성에스트로겐 조성물 |
PCT/KR2010/002349 WO2010120133A2 (ko) | 2009-04-15 | 2010-04-15 | 갱년기 또는 폐경기 증상의 예방 또는 완화용 식물성에스트로겐 조성물 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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KR1020090032821A KR101087608B1 (ko) | 2009-04-15 | 2009-04-15 | 갱년기 또는 폐경기 증상의 예방 또는 완화용 식물성에스트로겐 조성물 |
Related Child Applications (1)
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KR1020110011850A Division KR20110017419A (ko) | 2011-02-10 | 2011-02-10 | 갱년기 또는 폐경기 증상의 예방 또는 완화용 식물성에스트로겐 조성물 |
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Publication Number | Publication Date |
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KR20100114333A KR20100114333A (ko) | 2010-10-25 |
KR101087608B1 true KR101087608B1 (ko) | 2011-11-29 |
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KR1020090032821A KR101087608B1 (ko) | 2009-04-15 | 2009-04-15 | 갱년기 또는 폐경기 증상의 예방 또는 완화용 식물성에스트로겐 조성물 |
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WO (1) | WO2010120133A2 (ko) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20160049216A (ko) | 2014-10-27 | 2016-05-09 | 숙명여자대학교산학협력단 | 카르노식산을 유효성분으로 포함하는 갱년기 증상의 예방 또는 개선용 조성물 |
WO2018155956A1 (ko) * | 2017-02-24 | 2018-08-30 | 한국한의학연구원 | 백합 비늘줄기 추출물을 포함하는 인지장애의 예방 또는 치료용 약학 조성물 |
KR20190136512A (ko) | 2018-05-31 | 2019-12-10 | 숙명여자대학교산학협력단 | 마키베리 추출물, 당귀 추출물 및 시계꽃 추출물을 유효성분으로 함유하는 갱년기 증상 예방 또는 치료용 조성물 |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
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JP6564134B2 (ja) * | 2015-05-26 | 2019-08-21 | ニュートゥリー カンパニー リミテッド | モルシン、クワノンジ又は桑白皮を含有する筋肉疾患予防及び治療用又は筋機能改善用組成物 |
KR20160013227A (ko) | 2016-01-14 | 2016-02-03 | 김득수 | 녹용차 제조방법 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
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JP2005343872A (ja) * | 2004-06-07 | 2005-12-15 | Kao Corp | アロマターゼ活性化剤 |
EP1824341A4 (en) * | 2004-12-17 | 2008-05-21 | Bionovo Inc | ESTROGENIC EXTRACTS OF MORUS ALBA AND USES THEREOF |
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2009
- 2009-04-15 KR KR1020090032821A patent/KR101087608B1/ko active IP Right Grant
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2010
- 2010-04-15 WO PCT/KR2010/002349 patent/WO2010120133A2/ko active Application Filing
Non-Patent Citations (1)
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논문:한국식품과학회지* |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20160049216A (ko) | 2014-10-27 | 2016-05-09 | 숙명여자대학교산학협력단 | 카르노식산을 유효성분으로 포함하는 갱년기 증상의 예방 또는 개선용 조성물 |
WO2018155956A1 (ko) * | 2017-02-24 | 2018-08-30 | 한국한의학연구원 | 백합 비늘줄기 추출물을 포함하는 인지장애의 예방 또는 치료용 약학 조성물 |
KR20190136512A (ko) | 2018-05-31 | 2019-12-10 | 숙명여자대학교산학협력단 | 마키베리 추출물, 당귀 추출물 및 시계꽃 추출물을 유효성분으로 함유하는 갱년기 증상 예방 또는 치료용 조성물 |
Also Published As
Publication number | Publication date |
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WO2010120133A3 (ko) | 2011-03-03 |
WO2010120133A2 (ko) | 2010-10-21 |
KR20100114333A (ko) | 2010-10-25 |
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