KR100854776B1 - It is itchy and the pain relaxation composition and the manufacturing method - Google Patents

It is itchy and the pain relaxation composition and the manufacturing method Download PDF

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KR100854776B1
KR100854776B1 KR1020070022707A KR20070022707A KR100854776B1 KR 100854776 B1 KR100854776 B1 KR 100854776B1 KR 1020070022707 A KR1020070022707 A KR 1020070022707A KR 20070022707 A KR20070022707 A KR 20070022707A KR 100854776 B1 KR100854776 B1 KR 100854776B1
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extract
liter
liquid extract
water
mixing
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송창수
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송창수
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/35—Caprifoliaceae (Honeysuckle family)
    • A61K36/355—Lonicera (honeysuckle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A61K36/744—Gardenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

A method for preparing a composition for alleviating itch and pain is provided to obtain the composition which is applied to the affected part of a skin where bee stings are operated to mitigate the itch and the pain after the operation and remove fear against the bee stings. A method for preparing a composition for alleviating itch and pain comprises the steps of: (a) after finely cutting Myristica fragrans, Lonicera japonica, Gardenia seeds, Jasminum, Phryma leptostachya var. asiatica, Pterocarpus santalinus, Sorbus commixta, and Paeonia albiflora Pall into a certain size, respectively, washing them to prepare drugs; (b) mixing each 1.8 liter of the prepared Myristica fragrans, Lonicera japonica, Gardenia seeds, and Jasminum, Phryma leptostachya var. asiatica with 5.4 liter of water in each of a container and mixing each 1.8 liter of the prepared Pterocarpus santalinus, Sorbus commixta, and Paeonia albiflora Pall with 7.2 liter of water in each of a container; (c) after boiling down each of the mixture obtained from the step(b) at a temperature of 100 deg.C to have the water amount to become 1.8liter, respectively, cooling each of them at room temperature to prepare an extract of each of the drugs; (d) after putting each of the extract of the drugs in a distiller, heating it at a temperature of 100 deg.C until only remnants of the drugs remains, thereby distilling a colorless liquid phase extract; and (e) mixing 10 wt.% of the liquid extract of the Myristica fragrans, 10 wt.% of the liquid extract of the Lonicera japonica, 5 wt.% of the liquid extract of the Gardenia seeds, 20 wt.% of the liquid extract of the Jasminum, Phryma leptostachya var. asiatica, 20 wt.% of the liquid extract of the Pterocarpus santalinus, 5 wt.% of the liquid extract of the Sorbus commixta, and 5 wt.% of the liquid extract of the Paeonia albiflora Pall until with 5 wt.% of ethanol.

Description

가려움증 및 통증완화 조성물과 그 제조방법{It is itchy and the pain relaxation composition and the manufacturing method}Itching and pain relief composition and its manufacturing method

본 발명은 약재에서 증류되어 추출되는 추출물을 혼합한 액상의 조성물을 벌침 시술시 벌독의 성분은 그대로 두면서 피부에 생기는 가려움증 과 통증을 완화시켜 주도록 하는 가려움증 및 통증완화 조성물과 그 제조방법에 관한 것이다.The present invention relates to an itching and pain-relieving composition and a method for producing the same, which is used to reduce the itching and pain on the skin while leaving the components of the bee venom during the bee sting treatment of the liquid composition mixed with extracts distilled from the medicinal herbs.

일반적으로 벌독이란 벌이 가진 독을 말하는 것으로 그 효능은 옛날부터 잘 알려진 물질로써, 외국은 물론 국내에서도 예로부터 민간요법의 일종으로 벌침을 각종의 질병치료에 응용하여 왔다.Generally, bee venom refers to bee venom and its efficacy is well known since ancient times, and has been applied to bee sting as a kind of folk remedies for treatment of various diseases in Korea as well as foreign countries.

그러나, 벌독의 탁월한 효능에 의해 각종 질병치료에 사용이 되어 왔으나 벌침 시술 후 피부에 생기는 가려움이나 통증 등의 부작용이 있어 벌침을 시술하는데에 많은 두려움이 생기는 문제점이 있었다.However, it has been used for the treatment of various diseases by the excellent efficacy of bee venom, but there is a problem that a lot of fear occurs in the treatment of bee sting because there are side effects such as itching or pain in the skin after bee sting procedure.

본 발명은 상기와 같은 문제점을 해결하기 위하여 약재를 준비하는 제1단계와 약재와 물을 혼합하는 제2단계와 혼합된 약재와 물을 가열하여 추출하는 제3단계와 추출된 약재와 물을 증류하여 액상의 추출물로 만드는 제4단계와 액상의 추출 물을 혼합하는 제5단계로 이루어지는 조성물을 피부의 환부에 골고루 뿌려 벌침 시술이 필요한 환자들이 시술 후 가지게 되는 가려움증 및 통증을 완화시켜 주며, 또한 벌침에 대한 두려움을 제거하도록 하는 가려움증 및 통증완화 조성물과 그 제조방법을 제공한다.In order to solve the above problems, the first step of preparing the medicine and the second step of mixing the medicine and water and the second step of heating and extracting the mixed medicine and water and distilling the extracted medicine and water By spraying the composition consisting of the fourth step to make the liquid extract and the fifth step of mixing the liquid extract evenly sprayed on the affected area of the skin to alleviate the itching and pain that the patients need after the procedure, Itch and pain relief compositions to eliminate the fear of the present invention and a method for preparing the same.

본 발명의 가려움증 및 통증완화 조성물은 열매와 꽃잎, 줄기 또는 덩굴의 잎과 줄기에서 채취되는 육두구, 인동, 치자, 자스민, 파리풀 등의 약재와 나무의 줄기와 껍질 및 뿌리에서 채취되는 자단, 마가목, 작약 등의 약재를 각각 물과 혼합하여 가열한 후 얻어진 추출물을 다시 증류기에 의해 추출되는 액상의 추출물을 일정 비율로 혼합하여 조성한 것을 구성상의 기본 특징으로 한다.The itch and pain relief composition of the present invention is a nutmeg, honeysuckle, gardenia, jasmine, medicinal herbs such as jasmine, flyweed, etc., which are collected from the leaves and stems of fruit and petals, stems or vines, rosewood, rowan, It is a basic feature of the composition that the composition obtained by mixing the medicines such as peony and water with each other and then heating the extract obtained by mixing the extract of the liquid extracted by the distillation in a certain ratio.

이와 같이 이루어지는 가려움증 및 통증완화 조성물은 육두구 10%, 자단 10%, 마가목 5%, 인동 20%, 작약 20%, 치자 20%, 파리풀 5%, 자스민 5%, 에탄올 5%의 중량비로 이루어지는 것을 특징으로 한다.Itching and pain relief composition is made of a weight ratio of nutmeg 10%, rosewood 10%, rowan 5%, honeysuckle 20%, peony 20%, gardenia 20%, flygrass 5%, jasmine 5%, ethanol 5% It is done.

또한, 본 발명에 따른 가려움증 및 통증완화 조성물의 제조방법은 약재를 준비하는 제1단계와 약재와 물을 혼합하는 제2단계와 혼합된 약재와 물을 가열하여 추출하는 제3단계와 추출된 약재와 물을 증류하여 액상의 추출물로 만드는 제4단계와, 액상의 추출물을 혼합하는 제5단계로 이루어지는 것을 특징으로 한다.In addition, the method of preparing the itch and pain relief composition according to the present invention is the first step of preparing the medicine and the second step of mixing the medicinal herbs and water and the third step of extracting by heating water and the extracted medicinal herbs And a fourth step of distilling water into a liquid extract and a fifth step of mixing the liquid extract.

상기 제1단계는 육두구, 인동, 치자, 자스민, 파리풀 등과 같은 약재는 열매와 꽃잎, 줄기 또는 덩굴의 잎과 줄기에서 채취하여 일정 크기로 세절한 후 세척 하여 약재를 준비한다.In the first step, medicinal herbs, such as nutmeg, honeysuckle, gardenia, jasmine, flyweed, etc. are collected from the fruit and petals, stems or leaves and stems of the vines, cut to a certain size and washed to prepare the medicinal herbs.

또한, 본 발명의 또 다른 약재인 자단, 마가목, 작약 등은 나무의 줄기와 껍질 및 뿌리에서 채취되도록 하여 일정 크기로 세절한 후 세척하여 약재를 준비한다.In addition, rosewood, rowan, peony, etc., another medicine of the present invention is to be collected from the stem and bark and root of the tree to be cut to a certain size and washed to prepare the medicine.

상기 제2단계는 제1단계에서 준비된 약재 중 육두구, 인동, 치자, 자스민, 파리풀 등의 약재는 약재 1.8ℓ와 물 5.4ℓ의 부피비로 각각의 용기에 혼합한다.In the second step, medicinal herbs such as nutmeg, phosphorus, gardenia, jasmine, fly grass, etc., prepared in the first step, are mixed in each container in a volume ratio of 1.8 L of medicine and 5.4 L of water.

한편, 자단, 마가목, 작약 등의 약재는 약재 1.8ℓ와 물 7.2ℓ의 부피비로 각각의 용기에 혼합한다.Meanwhile, herbs such as rosewood, rowan, peony, etc. are mixed in each container in a volume ratio of 1.8 L of medicine and 7.2 L of water.

상기 제3단계는 각각의 용기에 혼합된 약재와 물을 100℃의 고온에서 가열하여 달인 후 상온에서 냉각시켜 추출물을 얻는다.The third step is decoction by heating the medicine and water mixed in each container at a high temperature of 100 ℃ decoction obtained by cooling at room temperature.

이때 물의 양이 1.8ℓ가 되도록 달이는 것이 바람직하다.At this time, it is preferable that the amount of water is decocted to 1.8 L.

한편, 상기의 추출물은 약재를 달이고 남은 찌꺼기와 약재 고유의 향과 색소를 내포하고 있는 액상의 물이다.On the other hand, the extract is a liquid water containing the residue and the inherent flavor and color of the medicinal herbs left over.

상기 제4단계는 제3단계에서 추출된 각각의 약재 추출물을 각각의 증류기에 투입하여 무색의 액상 추출물을 각각 증류 추출한다.In the fourth step, each of the medicinal herb extracts extracted in the third step is introduced into each distiller to distill each colorless liquid extract.

여기에서 무색의 액상 추출물은 증류에 의해 추출되므로 무색이며, 약재의 고유한 향은 90%이상 제거가 되고, 찌꺼기는 증류기의 여과기능에 의해 여과되어 걸러지게 된다.Here, the colorless liquid extract is colorless because it is extracted by distillation, the inherent aroma of the medicine is removed more than 90%, the residue is filtered and filtered by the filtration function of the still.

한편, 증류기는 100℃의 고온에서 약재의 찌꺼기만 남을때 까지 가열하도록 하는 것이 바람직 하다.On the other hand, it is preferable to heat the distillator until only the residue of the medicine remains at a high temperature of 100 ℃.

상기 제5단계는 제4단계 각각의 약재에서 증류되어 추출된 액상의 추출물에 에탄올을 일정비율로 혼합하여 가려움증 및 통증을 완화시켜 주는 조성물을 제조한다.The fifth step is to prepare a composition to relieve itching and pain by mixing ethanol in a predetermined ratio in the liquid extract extracted by distillation in each of the fourth step.

한편, 상기의 혼합비율은 육두구 10%, 자단 10%, 마가목 5%, 인동 20%, 작약 20%, 치자 20%, 파리풀 5%, 자스민 5%, 에탄올 5%의 중량비로 혼합하여 이루어지도록 하는 것이 바람직하다.On the other hand, the mixing ratio of nutmeg 10%, rosewood 10%, rowan 5%, phosphorus 20%, peony 20%, gardenia 20%, fly grass 5%, jasmine 5%, ethanol 5% to be made by mixing It is preferable.

본 발명의 가려움증 및 통증완화 조성물에 사용되는 각종 약재의 효능을 설명하면 다음과 같다.When explaining the efficacy of various medicines used in the itch and pain relief composition of the present invention.

육두구는 열매를 약재로 사용하게 되며, 감각을 둔화시키는 효과가 탁월하다.Nutmeg uses the fruit as a medicinal herb, it is excellent for slowing the senses.

자단은 나무의 껍질을 약재로 사용하며, 소염작용 및 가려움증에 효과가 있다.Rosewood uses the bark of the tree as an medicinal herb and is effective in anti-inflammatory and itching.

마가목은 나무의 줄기나 껍질을 약재로 사용하게 되며, 류마티스 관절염, 신경통, 기침 등에 좋은 효과가 있으며, 또한 통증과 염증을 삭이고, 갖가지 균을 죽이는 작용을 한다.Rowan use the stem or bark of the tree as a medicinal herb, rheumatoid arthritis, neuralgia, cough and other good effects, and also to reduce pain and inflammation, and to kill a variety of bacteria.

인동은 덩굴을 약재로 사용하게 되며, 열을 내리고 독을 풀고, 염증 질병에 탁월한 효과가 있으며, 이소시드와 사포닌 성분이 함유되어 있어 소염작용을 하는 효과가 있다.Phosphorus is used as a vine medicinal herb, heat and loosening the poison, excellent effects on inflammatory diseases, and contains isoside and saponin ingredients to have an anti-inflammatory effect.

작약은 나무의 뿌리를 약재로 사용하게 되며, 안식향산과 아스피라긴 등이 함유되어 있어 진통, 해열, 진경, 이뇨, 조혈, 지한 등의 효능을 가지고 있다.Peony uses the root of the tree as a medicinal herb, and contains benzoic acid and aspirin, which has the effects of analgesic, antipyretic, menstrual, diuretic, hematopoietic, and latent.

치자는 열매를 약재로 사용하게 되며, 청열작용을 하여 아토피 및 가려움증 에 효과가 있다. Gardenia fruit is used as a medicinal herb, and it is effective in atopic dermatitis and itching due to the clearing action.

파리풀은 식물전체를 약재로 사용하며, 해독, 살충의 효능이 있어 가려움증에 효과가 있다.Flyweed uses the whole plant as a medicinal herb, and it is effective in itching due to detoxification and insecticidal effects.

자스민은 줄기, 잎, 꽃 등을 약재로 사용하며, 신경을 안정시켜주는 효과가 있다.Jasmine uses stems, leaves, flowers, etc. as medicines, and it has an effect to stabilize nerves.

에탄올은 시원한 느낌과 부패를 방지하는 효과가 있다.Ethanol feels cool and prevents decay.

한편, 가려움증 및 통증완화제 조성물은 연고제로 형성시켜 사용하여도 무방하다.On the other hand, itching and pain relief composition may be used to form an ointment.

상기와 같이 본 발명에 의해 제조된 조성물은 벌침을 시술하는 피부의 환부에 골고루 뿌려 벌침 시술이 필요한 환자들이 시술 후 가지게 되는 가려움증 및 통증을 완하시켜 주며, 또한 벌침에 대한 두려움을 제거하도록 하는 것이다.As described above, the composition prepared by the present invention is to evenly spread the affected areas of the skin to bee acupuncture to relieve the itching and pain that the patient needs a bee after the procedure, and also to eliminate the fear of bee sting.

본 발명은 벌침을 시술하는 피부의 환부에 골고루 뿌려 벌침 시술이 필요한 환자들이 시술 후 가지게 되는 가려움증 및 통증을 완화시켜 주며, 또한 벌침에 대한 두려움을 제거하도록 하는 이점이 있다.The present invention is evenly sprayed on the affected area of the skin to bee acupuncture to relieve the itching and pain that the patients need beeing after the procedure, and also has the advantage to eliminate the fear of bee sting.

Claims (4)

삭제delete 삭제delete 삭제delete 육두구, 인동, 치자, 자스민, 파리풀은 열매와 꽃잎, 줄기 또는 덩굴의 잎과 줄기에서 채취하도록 하며, 자단, 마가목, 작약은 나무의 줄기와 껍질 및 뿌리에서 채취되도록 하여 일정 크기로 세절한 후 세척하여 약재를 준비하는 제1단계와,Nutmeg, honeysuckle, gardenia, jasmine and fly grass should be collected from fruit and petals, stems or leaves of vines, and rosewood, rowan and peony should be collected from the stems, bark and roots of trees, and then washed to a certain size. The first step in preparing the medicine, 제1단계에서 준비된 약재 중 육두구, 인동, 치자, 자스민, 파리풀은 약재 1.8ℓ와 물 5.4ℓ의 부피비로 각각의 용기에 혼합하고, 자단, 마가목, 작약은 약재 1.8ℓ와 물 7.2ℓ의 부피비로 각각의 용기에 혼합하는 제2단계와,Nutmeg, indong, gardenia, jasmine, and fly grass are mixed in each container in the volume ratio of 1.8 liter of medicinal herbs and 5.4 liters of water, and rosewood, rowan and peony are prepared in the volume ratio of 1.8 liter of medicinal herbs and 7.2 liter of water. A second step of mixing in each container, 제2단계에서 각각의 용기에 혼합된 약재와 물을 100℃의 고온에서 물의 양이 1.8ℓ되도록 가열하여 달인 후 상온에서 냉각시켜 추출물을 얻는 제3단계와,A third step of obtaining the extract by heating the medicine and water mixed in each container in a second step so that the amount of water is 1.8 L at a high temperature of 100 ° C., and then cooling it at room temperature; 제3단계에서 추출된 각각의 약재 추출물을 각각의 증류기에 투입하여 100℃의 고온에서 약재의 찌꺼기만 남을때까지 가열하여 무색의 액상 추출물이 증류되도록 하는 제4단계와,A fourth step of putting each of the medicinal extracts extracted in the third step into each distiller to heat only the residue of the medicinal herbs at a high temperature of 100 ° C. to distill the colorless liquid extract; 제4단계 각각의 약재에서 추출된 육두구 10%, 자단 10%, 마가목 5%, 인동 20%, 작약 20%, 치자 20%, 파리풀 5%, 자스민 5%의 액상의 추출물에 에탄올 5%의 중량비로 혼합하는 제5단계로 이루어지는 것을 특징으로 하는 가려움증 및 통증완화 조성물 제조방법.4% weight ratio of nutmeg 5% ethanol to liquid extracts of nutmeg 10%, rosewood 10%, rowan 5%, honeysuckle 20%, peony 20%, gardenia 20%, fly grass 5%, jasmine 5% Itching and pain relief composition manufacturing method comprising the fifth step of mixing with.
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KR101721007B1 (en) 2016-07-08 2017-03-29 김원주 Antidotes composition for venom of venomous insects
KR101767261B1 (en) * 2010-04-27 2017-08-10 (주)뉴트리 Composition for alleviating itchiness or improving skin wound comprising macelignan or nutmeg extract as an active ingredient
CN108403872A (en) * 2018-05-07 2018-08-17 深圳润邦之家生物科技有限公司 A kind of dispeling wind and dehumidification is dispelled pain herbal essences liquid

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WO2003006144A1 (en) * 2001-07-10 2003-01-23 Ecolab Inc. Flow-based chemical dispense system
KR20070020326A (en) * 2004-06-21 2007-02-20 아베다 코포레이션 Solvent based plant extracts
KR20070082526A (en) * 2006-02-16 2007-08-21 코세 코퍼레이션 Pharmaceutical agent containing the betula platyphylla sukatchev var. japonica hara extract as an effective ingredient and its use

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101767261B1 (en) * 2010-04-27 2017-08-10 (주)뉴트리 Composition for alleviating itchiness or improving skin wound comprising macelignan or nutmeg extract as an active ingredient
KR101721007B1 (en) 2016-07-08 2017-03-29 김원주 Antidotes composition for venom of venomous insects
CN108403872A (en) * 2018-05-07 2018-08-17 深圳润邦之家生物科技有限公司 A kind of dispeling wind and dehumidification is dispelled pain herbal essences liquid

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