KR100463920B1 - 신규 세프디토렌 피복실 메지틸렌 설폰산염 및 그 제조방법 - Google Patents
신규 세프디토렌 피복실 메지틸렌 설폰산염 및 그 제조방법 Download PDFInfo
- Publication number
- KR100463920B1 KR100463920B1 KR10-2002-0063952A KR20020063952A KR100463920B1 KR 100463920 B1 KR100463920 B1 KR 100463920B1 KR 20020063952 A KR20020063952 A KR 20020063952A KR 100463920 B1 KR100463920 B1 KR 100463920B1
- Authority
- KR
- South Korea
- Prior art keywords
- sulfonic acid
- ceftitorene
- coating chamber
- structural formula
- acid salt
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/02—Preparation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/48—Methylene radicals, substituted by hetero rings
- C07D501/56—Methylene radicals, substituted by hetero rings with the 7-amino radical acylated by carboxylic acids containing hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
Abstract
Description
Claims (3)
- 다음의 일반 구조식 (I)을 가지는 세프디토렌 피복실 메지틸렌 설폰산 염(Ⅰ)상기식에서 n은 1 내지 2이다.
- 다음 구조식 (IV)의 세프디토렌 피복실을 다음 구조식 (V)의 메지틸렌 설폰산과 반응시켜서 다음 일반 구조식 (I)의 세프디토렌 피복실 메지틸렌 설폰산 염을 제조하는 방법.(Ⅰ)(Ⅳ) (Ⅴ)상기식에서 n은 1 내지 2이다.
- 다음 구조식 (II)의 세프디토렌을 다음 구조식 (III)의 피발로일옥시메틸 아이오다이드와 반응시켜서 다음 구조식 (IV)의 세프디토렌 피복실을 제조하고, 이 구조식 (IV)의 세프디토렌 피복실을 다음 구조식 (V)의 메지틸렌 설폰산과 반응시켜서 다음 일반 구조식 (I)의 세프디토렌 피복실 메지틸렌 설폰산 염을 제조하는 방법.(Ⅰ)(Ⅱ) (Ⅲ)(Ⅳ) (Ⅴ)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR10-2002-0063952A KR100463920B1 (ko) | 2002-10-18 | 2002-10-18 | 신규 세프디토렌 피복실 메지틸렌 설폰산염 및 그 제조방법 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR10-2002-0063952A KR100463920B1 (ko) | 2002-10-18 | 2002-10-18 | 신규 세프디토렌 피복실 메지틸렌 설폰산염 및 그 제조방법 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR20040035196A KR20040035196A (ko) | 2004-04-29 |
KR100463920B1 true KR100463920B1 (ko) | 2004-12-30 |
Family
ID=37334161
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR10-2002-0063952A KR100463920B1 (ko) | 2002-10-18 | 2002-10-18 | 신규 세프디토렌 피복실 메지틸렌 설폰산염 및 그 제조방법 |
Country Status (1)
Country | Link |
---|---|
KR (1) | KR100463920B1 (ko) |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR930003121A (ko) * | 1991-07-31 | 1993-02-24 | 이헌조 | Vcr의 예약 녹화후 자동 리와인드 장치 및 그 방법 |
KR940000112A (ko) * | 1992-06-01 | 1994-01-03 | 김태희 | 결명자를 분리한 가공물질 |
KR0133560B1 (ko) * | 1987-09-14 | 1998-04-23 | 후지사와 도모기찌로 | 세펨 화합물, 이의 제조방법 및 이를 포함하는 약제학적 조성물 |
US5861508A (en) * | 1994-06-14 | 1999-01-19 | Biochemie Gesellschaft M.B.H. | Purification of a cephalosporin salt |
US5994340A (en) * | 1997-08-29 | 1999-11-30 | Synphar Laboratories, Inc. | Azetidinone derivatives as β-lactamase inhibitors |
-
2002
- 2002-10-18 KR KR10-2002-0063952A patent/KR100463920B1/ko active IP Right Grant
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR0133560B1 (ko) * | 1987-09-14 | 1998-04-23 | 후지사와 도모기찌로 | 세펨 화합물, 이의 제조방법 및 이를 포함하는 약제학적 조성물 |
KR930003121A (ko) * | 1991-07-31 | 1993-02-24 | 이헌조 | Vcr의 예약 녹화후 자동 리와인드 장치 및 그 방법 |
KR940000112A (ko) * | 1992-06-01 | 1994-01-03 | 김태희 | 결명자를 분리한 가공물질 |
US5861508A (en) * | 1994-06-14 | 1999-01-19 | Biochemie Gesellschaft M.B.H. | Purification of a cephalosporin salt |
US5994340A (en) * | 1997-08-29 | 1999-11-30 | Synphar Laboratories, Inc. | Azetidinone derivatives as β-lactamase inhibitors |
Also Published As
Publication number | Publication date |
---|---|
KR20040035196A (ko) | 2004-04-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
KR870000826B1 (ko) | 세팔로스포린 유도체의 제조방법 | |
JPS6153359B2 (ko) | ||
EP0264091B1 (en) | 3-propenylcephem derivative, preparation thereof, chemical intermediates therein, pharmaceutical composition and use | |
EP0329008B1 (de) | Cephalosporinderivative und Verfahren zu ihrer Herstellung | |
Kakeya et al. | KY-109, A NEW BIFUNCTIONAL PRO-DRUG OF A CEPHALOSPORIN CHEMISTRY, PHYSICO-CHEMICAL AND BIOLOGICAL PROPERTIES | |
KR910008350B1 (ko) | 세팔로스포린 에스테르 유도체의 제조방법 | |
KR100463920B1 (ko) | 신규 세프디토렌 피복실 메지틸렌 설폰산염 및 그 제조방법 | |
US3865820A (en) | Acylamino-cephalosporanic acids | |
IE902115A1 (en) | Crystalline cephem acid addition salts and processes for their preparation | |
FI108435B (fi) | Menetelmõ terapeuttisesti kõytt÷kelpoisten 3-kefem-4-karboksyylihappo-1-(2,2-dimetyylipropionyylioksi)-etyyliesterin poolittomamman diastereomeerin kiteisten happoadditiosuolojen valmistamiseksi | |
EP0026811B1 (en) | Cephalosporin derivatives | |
US4451399A (en) | Imidazolecarboxylic acid derivatives | |
US4124762A (en) | 7-[(Pyridylthiomethyl)phenyl]acetamido-cephalosporin derivatives | |
JPS5973590A (ja) | 新規なセフアロスポリン誘導体,その製造法およびそれを含有する抗生物質薬剤 | |
EP0334281A2 (de) | Cephalosporinderivate und Verfahren zu ihrer Herstellung | |
WO1997024359A1 (en) | Novel cephalosporin derivatives and processes for the preparation thereof | |
US4124761A (en) | 7-[(substituted-thiomethyl)phenyl] acetamidocephalosporin derivatives | |
KR100423890B1 (ko) | 세팔로스포린 유도체의 새로운 제조방법 | |
US4172942A (en) | 7-[(Substituted-thiomethyl)phenyl]acetamidocephalosporin derivatives | |
EP0321562B1 (en) | Crystalline cephalosporin compounds, process for their preparation, and intermediates for their preparation | |
US4159327A (en) | Cephalosporin derivatives, compositions and method of use | |
US4044047A (en) | Intermediates for preparing substituted phenylglycylcephalosporins | |
KR900007184B1 (ko) | 세팔로스포린 유도체의 제조방법 | |
US4497811A (en) | 1-Oxadethiacephalosporin compound and antibacterial agent containing the _same | |
EP0390066B1 (de) | Cephalosporinderivate und Verfahren zu ihrer Herstellung |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A201 | Request for examination | ||
E701 | Decision to grant or registration of patent right | ||
GRNT | Written decision to grant | ||
FPAY | Annual fee payment |
Payment date: 20121220 Year of fee payment: 9 |
|
FPAY | Annual fee payment |
Payment date: 20131220 Year of fee payment: 10 |
|
FPAY | Annual fee payment |
Payment date: 20141022 Year of fee payment: 11 |
|
FPAY | Annual fee payment |
Payment date: 20150925 Year of fee payment: 12 |
|
FPAY | Annual fee payment |
Payment date: 20161219 Year of fee payment: 13 |
|
FPAY | Annual fee payment |
Payment date: 20171219 Year of fee payment: 14 |
|
FPAY | Annual fee payment |
Payment date: 20181031 Year of fee payment: 15 |
|
FPAY | Annual fee payment |
Payment date: 20191001 Year of fee payment: 16 |