KR100431273B1 - Extracting substance Capsulating Method and Equipment - Google Patents

Extracting substance Capsulating Method and Equipment Download PDF

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Publication number
KR100431273B1
KR100431273B1 KR10-2001-0041734A KR20010041734A KR100431273B1 KR 100431273 B1 KR100431273 B1 KR 100431273B1 KR 20010041734 A KR20010041734 A KR 20010041734A KR 100431273 B1 KR100431273 B1 KR 100431273B1
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extract
liquid supply
coating
supply pipe
liquid
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KR10-2001-0041734A
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Korean (ko)
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KR20030006160A (en
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공영준
홍거표
강태수
이신영
홍정기
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강원도
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S53/00—Package making
    • Y10S53/90—Capsules

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Formation And Processing Of Food Products (AREA)
  • Manufacturing Of Micro-Capsules (AREA)

Abstract

본 발명은 특정용도의 생약재 또는 과일 및 특정The present invention is a herbal or fruit of a particular use and specific

식물의 잎이나 열매에서 추출된 추출액을 코팅 캡슐화하는 추출액 코팅 캡슐제조 장치 및 방법에 관한 것으로 본발명의 목적은 액상의 추출액의 외표면을 액상의 알긴닌등 코팅액으로 코팅하여 코팅액 피막이 형성되게 하여 코팅 피막을 응집제로써 고화 또는 겔화시켜 추출액을 캡슐화하는 것으로 일련의 상기 작업을 하나의 장치에 의하여 자동으로 달성되도록 하는 추출액 캡슐화 자동화 장치 및 그 방법을 제공하는데 그 특징이 있는데, 본 발명에 따른 추출액 캡슐화 자동화장치 및 방법은 이중관을 통해 추출액과 코팅액을 동시에 공급하며, 내측관을 통해 추출액을 공급하고 외측관을 통해 코팅액을 공급하여 추출액의 방울의 외표면에 상당한 점성을 갖는 코팅액의 피막을 형성하도록 하여 코팅액 피막이 형성된 추출액방울을 만들고, 코팅액 피막이 형성된 추출액방울을 응집제에 넣어 코팅액 피막을 고화 또는 겔화하는 추출액 캡슐화 방법 및 원료공급부(100)와 데스크부(200)가 구비되고, 원료공급부(100)는 추출액공급부(110)와 코팅액공급부(120) 및 원료공급노즐(130)로 구성되며, 상기 추출액공급부(110)는 추출액공급관(111)과 펌프(112)로 이루어지며, 상기 코팅액공급부(120)는 펌프와 함께 상기 추출액공급관(111) 보다 약간 더큰 직경의 코팅액공급관(121)이 형성되며, 원료공급노즐(130)은 코팅액공급관(121)과 추출액공급관(111)은 그 자유 단부에 가까운 소정의 부분에서 서로 합관이되어 이중관이 형성되는 것으로 추출액공급관(111)이코팅액공급관(121)을 뚫고 들어가 수용되는 형태로 이중관의 형태를 취한 추출액 캡슐화 자동화 장치로 이루어진다.The present invention relates to an extract coating capsule manufacturing apparatus and method for coating and encapsulating an extract extracted from a leaf or fruit of a plant. An object of the present invention is to coat an outer surface of a liquid extract with a liquid solution of alginine to form a coating liquid coating. The present invention provides an extract liquid encapsulation automation device and a method for automatically accomplishing a series of the above operations by encapsulating an extract by solidifying or gelling a film with a coagulant, and a method thereof. The extract encapsulation automation according to the present invention is provided. The apparatus and method simultaneously supply the extract and the coating liquid through the double tube, and supply the extract through the inner tube and the coating liquid through the outer tube to form a film of coating liquid having a substantial viscosity on the outer surface of the droplet of extract. Make an extract drop formed with a coating, coating liquid An extract liquid encapsulation method and a raw material supply part 100 and a desk part 200 are provided to put an extract droplet formed with a film into a flocculant to solidify or gel the coating liquid. The raw material supply part 100 includes an extract liquid supply part 110 and a coating liquid supply part 120. ) And a raw material supply nozzle 130, wherein the extract liquid supply unit 110 is composed of an extract liquid supply pipe 111 and a pump 112, and the coating solution supply unit 120 is provided with a pump than the extract liquid supply pipe 111. The coating liquid supply pipe 121 having a slightly larger diameter is formed, and the raw material supply nozzle 130 is formed in a double pipe by combining the coating liquid supply pipe 121 and the extract liquid supply pipe 111 with each other at a predetermined portion near the free end thereof. Extract liquid supply pipe 111 is formed through the coating liquid supply pipe 121 is formed into an extract liquid encapsulation automation device taking the form of a double tube.

Description

추출액 캡슐화 자동화 장치 및 방법{Extracting substance Capsulating Method and Equipment}Extracting substance capsulating method and equipment

본 발명은 특정용도의 생약재 또는 과일 및 특정 식물의 잎이나 열매에서 추출된 추출액을 코팅 캡슐화하는 추출액 코팅 캡슐제조 장치 및 방법에 관한 것이다.The present invention relates to an extract coating capsule manufacturing apparatus and method for coating encapsulating the extract extracted from the leaves or berries of the herbal or fruit and fruit of a specific use.

일반적으로 인체에 유익한 특정 약용식물에서 액을 추출하여 그 추출액을 복용하게 되는데, 추출액이 혀에 닿게 되면 불쾌한 느낌을 주기에 추출액을 타원체 형상의 종래캡슐에 넣어 물과 함께 복용한다.In general, extract the liquid from a particular medicinal plant that is beneficial to the human body to take the extract, and when the extract comes in contact with the tongue to give an unpleasant feeling to take the extract with the water in the conventional capsule of the ellipsoid shape.

그런데, 이와 같이 추출액을 넣은 종래의 캡슐에 추출액을 넣는 작업은 먼저 타원체 캡슐을 제조한 다음 캡슐에 추출액을 넣고 캡슐을 밀봉하는 작업으로 이루어져 있기에 그만큼 작업이 복잡하고 소요되는 기기 및 작업이 많고 복잡하기에 제조 단가가 높을 수 밖에 없다.However, the operation of putting the extract in the conventional capsule in which the extract is added is made of an ellipsoid capsule first, and then the extract is put in the capsule and the capsule is sealed, so the work is complicated and requires a lot of equipment and work. Inevitably, manufacturing costs are high.

상기와 같은 문제점을 해결하기 위하여 본 발명이 창안된 것인데, 본 발명의 목적은 액상의 추출액의 외표면을 액상의 알긴닌등 코팅액으로 코팅하여 코팅액 피막이 형성되게 하여 코팅 피막을 응집제로써 고화 또는 겔화시켜 추출액을 캡슐화하는 것으로 일련의 상기 작업을 하나의 장치에 의하여 자동으로 달성되도록 하는 추출액 캡슐화 자동화 장치 및 그 방법을 제공하는데 그 특징이 있다.In order to solve the above problems, the present invention was invented, and an object of the present invention is to coat the outer surface of the liquid extract with a liquid coating solution such as alginine to form a coating liquid film, thereby solidifying or gelling the coating film as a flocculant. It is a feature of the present invention to provide an extract liquid encapsulation automation device and a method for encapsulating the extract liquid such that a series of said operations are automatically accomplished by one device.

도 1은 본발명에 따른 추출액 캡슐화 자동화 장치의 개략적 정면도1 is a schematic front view of an extract liquid encapsulation automation device according to the present invention;

도 2는 본발명에 따른 추출액 캡슐화 자동화 장치의 부분절개 사시도Figure 2 is a partial cutaway perspective view of the extract liquid encapsulation automation device according to the present invention

도 3는 본발명에 따른 장치에 있어서 원료공급부의 일부분 단면도 및 작용 상태 설명도Figure 3 is a partial cross-sectional view and action state explanatory drawing of the raw material supplier in the device according to the present invention

도 4은 본발명에 따른 장치에 있어서 원료공급노즐의 구조 변화에 따른 코 팅 피막이 형성된 추출액방울의 형태 변화상태 설명도4 is an explanatory view of the shape change state of the extract droplets formed with a coating film according to the structural change of the raw material supply nozzle in the apparatus according to the present invention

***도면의 주요부호에 대한 설명******* Explanation of the main symbols in the drawings ****

100 : 원료공급부 200 : 데스크부100: raw material supply part 200: desk part

110 : 추출액공급부 120 : 코팅액공급부 130 : 원료공급노즐110: extract liquid supply unit 120: coating liquid supply unit 130: raw material supply nozzle

111 : 추출액공급관 112 : 펌프 121 : 코팅액공급관111: extraction liquid supply pipe 112: pump 121: coating liquid supply pipe

e : 추출액 c : 코팅액e: extract liquid c: coating liquid

g : 코팅액 피막이 형성된 추출액 방울g: Droplet of the extract liquid with a coating liquid film formed

도 1은 본 발명에 따른 자동 추출액 캡슐 자동화 장치의 개략적 정면도이고, 도 2는 본발명에 따른 추출액 캡슐화 자동화 장치의 부분절개 사시도이며, 도 3는 본발명에 따른 장치에 있어서 원료공급부의 일부분 단면도 및 작용 상태 설명도이다.1 is a schematic front view of an automatic extract capsule automation device according to the present invention, Figure 2 is a partial cutaway perspective view of the extract liquid encapsulation automation device according to the present invention, Figure 3 is a partial cross-sectional view of the raw material supply in the device according to the present invention and It is explanatory drawing of action state.

도 1 내지 도 3에 도시된 바와 같은 본 발명의 추출액 캡슐화 장치는 원료공급부(100)와 데스크부(200)가 구비되는데, 상기 원료공급부(100)는 추출액공급부(110)와 코팅액공급부(120) 및 원료공급노즐(130)로 구성되는데, 상기 추출액공급부(110)는 추출액공급관(111)과 펌프(112)로 이루어지며, 상기 코팅액공급부(120)는 펌프(도시 생략)를 포함하고 상기 추출액공급관(111) 보다 약간 더큰 직경의 코팅액공급관(121)이 형성된다.1 to 3, the extract liquid encapsulation apparatus of the present invention is provided with a raw material supply unit 100 and a desk unit 200, the raw material supply unit 100 is the extract liquid supply unit 110 and the coating liquid supply unit 120 And a raw material supply nozzle 130, wherein the extract liquid supply unit 110 includes an extract liquid supply pipe 111 and a pump 112, and the coating solution supply unit 120 includes a pump (not shown). A coating liquid supply pipe 121 having a diameter slightly larger than that of 111 is formed.

그런데 상기 코팅액공급관(121)과 추출액공급관(111)은 그 자유 단부 부분에서 서로 합관이되는데, 그 합관형태가 도 2 및 도 3에 도시된 바와 같이 이루어진다. 즉 추출액공급관(111)이 코팅액공급관(121)을 뚫고 들어가 수용되는 형태로 이중관의 형태를 이루지는데, 이와 같이 추출액공급관(111)과 코팅액공급관(121)이 합관된어 이중관을 이루는 부분을 본명세서에서 원료공급노즐(130)이라 명명하기로 한다.By the way, the coating liquid supply pipe 121 and the extraction liquid supply pipe 111 is a jointed with each other at its free end portion, the union form is made as shown in Figs. That is, the extract liquid supply pipe 111 penetrates through the coating liquid supply pipe 121 to form a double tube. The extract liquid supply pipe 111 and the coating liquid supply pipe 121 are combined to form a double tube. In the raw material supply nozzle 130 will be named.

이와 같은 원료공급노즐(130)을 형성하는 추출액공급관(111)의 자유단부는 코팅액공급관(121)의 자유단부보다 약간 더 길게 형성된다.(도 2 및 도 3에서 그길이차이를 h로 표시하였다.)The free end of the extraction liquid supply pipe 111 forming the raw material supply nozzle 130 is formed slightly longer than the free end of the coating liquid supply pipe 121. (The length difference is shown by h in FIGS. 2 and 3. .)

그리고 상기 데스크부(200)는 데스크프레임에 구획되어 상부측에 농도가 조절된 염화칼슘(CaCl2) 수용액등 응집제가 들어있는 응집제용기(210)와 응집제 용기(210)의 하부에 냉각장치의 흡열파이프(220)가 형성되어 상측의 응집제용기(210)를 냉각하도록 하고있다.In addition, the desk unit 200 is partitioned into a desk frame and the heat absorbing pipe of the cooling device at the bottom of the coagulant container 210 and the coagulant container 210 containing the coagulant such as calcium chloride (CaCl 2 ) aqueous solution of which the concentration is adjusted on the upper side. 220 is formed to cool the coagulant container 210 of the upper side.

이상과 같은 구성으로 이루어진 본 발명의 추출액 캡슐화 자동화 장치는 추출액공급관(111)과 코팅액공급관(121)을 통해 추출액(e)과 상당한 점성을 갖는 코팅액(c)이 공급되는데, 추출액(e)과 코팅액(c)은 상기 각기의 공급관내에서 소정의 압력으로 공급되어 코팅액(c)은 그 점성 때문에 원료공급노즐(130)에 형성된 코팅액공급관(121)의 자유단부에서 약간 늘려뜨려 지면서 추출액공급관(111)의 자유단부 아래로 매달리는 형상을 취하고 동시에 추출액은 내측에 형성된 추출액공급관(111)의 자유단부에서 밀려 나와 상기 코팅액공급관(121)에서 밀려나와 매달려 있는 코팅액내로 밀고 들어가 전체적으로 추출액을 코팅액이 싼 상태에서 코팅된 추출액 방울(g)이 형성된다.(도 4 참조)The extract liquid encapsulation automation device of the present invention having the above configuration is supplied with a coating liquid (c) having a significant viscosity with the extract liquid (e) through the extract liquid supply pipe (111) and the coating liquid supply pipe (121), the extract liquid (e) and the coating liquid (c) is supplied at a predetermined pressure in the respective supply pipes so that the coating liquid (c) is slightly stretched at the free end of the coating liquid supply pipe 121 formed on the raw material supply nozzle 130 due to its viscosity, and thus the extraction liquid supply pipe 111 At the same time, the extract is suspended from the free end of the extract liquid supply pipe 111 formed at the inner side of the extract liquid supply pipe 111, pushed out of the coating liquid supply pipe 121, and pushed into the hanging coating liquid. The extracted extract drop g is formed (see FIG. 4).

이상태에서 추출액공급부(110)의 펌프(112)가 작동하여 약간의 압력을 추출액공급관(111)내 수용된 추출액(e)에 가하게 되면 추출액(e)이 밀려나와 더 많은 양의 추출액(e)이 코팅액(c)내로 들어가게 되는데 이렇게 되면 에서 만들어져 매달린 코팅된 추출액방울(g)이 약간더 크게 되어 전체중량이 커져 원료공급노즐(130)에서 떨어져 나와 데스크부(200)의 응집제용기(210)내로 들어가 응집제(i)와 만나게 된다.(도 4 참조)In this state, when the pump 112 of the extraction liquid supply unit 110 is operated to apply a slight pressure to the extraction liquid e contained in the extraction liquid supply pipe 111, the extraction liquid e is pushed out and a larger amount of the extraction liquid e is coated. (c) is to enter into the coating liquid droplets (g) is made and suspended in the coating (g) is slightly larger so that the total weight is larger, coming off from the raw material supply nozzle 130 and enter the flocculent container 210 of the desk portion 200 into the flocculant (i) (see FIG. 4).

응집제용기(210)내에서 원료공급노즐(130)에서 떨어져 나온 코팅된 추출액방울(g)의 액상상태인 코팅액(c) 피막은 응집제(i)와 만나 응집반응을 일으켜 고화 또는 겔(GELL)화가 일어나 액상의 추출액(e)을 수용한 캡슐기능을 하게 된다.The coating liquid (c) film in the liquid state of the coated extract droplets (g) separated from the raw material supply nozzle 130 in the coagulant container 210 meets with the coagulant (i) to cause an agglomeration reaction so that the solidification or gelling is performed. It takes place to function as a capsule containing the liquid extract (e).

예를 들어 코팅액이 알긴산이라면 응집제로 염화칼슘을 사용하면 추출액방울(g)을 싸고 있는 액상의 알긴산이 염화칼슘과 반응하여 응집현상이 일어나 고화 또는 겔상이 되어 추출액을 캡슐화하는 것이다.For example, if the coating solution is alginic acid, when calcium chloride is used as the flocculant, the liquid alginic acid surrounding the extract drop (g) reacts with the calcium chloride to cause coagulation, which solidifies or gels to encapsulate the extract.

코팅액 피막의 고화 또는 겔화의 시간을 촉진하기위하여 응집제의 온도를 낮게 유지함이 유리하다. 응집제 온도를 낮추기위하여 냉각장치(도시 생략)를 가동하여 응집제용기(210)의 하부측에 형성된 흡열파이프(220)에서 응집제용기(210)의 열을 빼앗도록 한다.It is advantageous to keep the temperature of the flocculent low to promote the time of solidification or gelling of the coating liquid coating. In order to lower the flocculant temperature, a cooling device (not shown) is operated to deprive the heat of the flocculant container 210 from the endothermic pipe 220 formed on the lower side of the flocculant container 210.

그런데, 상기 원료공급노즐(130)에 있어서 추출액공급관(111)의 자유단부가 코팅액공급관(121)의 자유단부보다 약간 더 길게 형성됨은 상술한 바와 같고 그 길이차를 h라 할 때 길이 h가 길수록 코팅액 피막이 형성된 추출액방울(g)의 형상이 물방울형상 또는 달걀형상을 이루고 반대로 h가 짧을수록 구(球)에 가까운 형상을 이룬다. 이와 같은 거동을 도 4에 도시하고 있다.(도 4에 있어 h1〈 h2〈 h3의 관계를 갖는다.)However, in the raw material supply nozzle 130, the free end of the extract liquid supply pipe 111 is formed to be slightly longer than the free end of the coating liquid supply pipe 121, as described above. The shape of the extract droplet (g) in which the coating liquid coating is formed forms a droplet shape or an egg shape. On the contrary, the shorter the h, the closer the sphere is. This is the same behavior shown in Figure 4 (in Figure 4 has a relationship of h 1 <h 2 <h 3 .)

상술한 바처럼 코팅액이 상당한 점도를 갖는 것이 일반적이므로 원료공급노즐(130)을 이루는 코팅액공급관(121)의 자유단부의 내경(內徑) 형상에 변화를 가하면 코팅된 피막의 외표면의 형태를 변하게 할 수 있다.As described above, since the coating liquid generally has a significant viscosity, a change in the inner diameter of the free end of the coating liquid supply pipe 121 forming the raw material supply nozzle 130 changes the shape of the outer surface of the coated film. can do.

본 발명에 따른 장치 및 방법이 적용되는 추출액은 생약재(生藥材)의 추출액 뿐만아니라 천연과일의 과즙 및 기타 식물이나 생물 등에서 추출된 추출액을 포함한다.Extracts to which the apparatus and method according to the present invention are applied include not only extracts of herbal medicines, but also extracts from natural fruit juices and other plants and organisms.

이상에서 서술한 바와 같이 본 발명의 추출액 캡슐화 자동화 장치 및 방법에 의하여 추출액을 코팅제로 캡슐화하기에 종래의 방법에 비하여 지극히 간단하고 제조가 용이하며 이에 따라 생산성이 크게 향상되어 경제적인 제조장치 및 방법이라 할 것이다.As described above, the extract liquid is encapsulated in a coating agent by the extract liquid encapsulation automation device and method of the present invention. something to do.

Claims (4)

삭제delete 원료공급부(100)와 데스크부(200)가 구비되고;A raw material supply unit 100 and a desk unit 200 are provided; 원료공급부(100)는 추출액공급부(110)와 코팅액공급부(120) 및 원료공급노즐(130)로 구성되며;The raw material supply unit 100 includes an extract liquid supply unit 110, a coating liquid supply unit 120, and a raw material supply nozzle 130; 상기 추출액공급부(110)는 추출액공급관(111)과 펌프(112)로 이루어지며,The extract liquid supply unit 110 is composed of an extract liquid supply pipe 111 and the pump 112, 상기 코팅액공급부(120)는 펌프와 함께 상기 추출액공급관(111) 보다 약간 더 큰 직경의 코팅액공급관(121)이 형성되며;The coating liquid supply unit 120 is formed with a pump and a coating liquid supply tube 121 having a diameter slightly larger than that of the extract liquid supply tube 111; 상기 원료공급노즐(130)은 코팅액공급관(121)과 추출액공급관(111)의 자유 단부에 가까운 소정의 부분에서 서로 합관이 되어 이중관이 형성되는 것으로 추출액공급관(111)이 코팅액공급관(121)을 뚫고 들어가 수용되는 형태로 이중관의 형태를 취하고, 내측관인 추출액공급관(111)의 자유단부가 외측관인 코팅액공급관(121)보다 더 길게 나와 있는 구조로 된 추출액 캡슐화 자동화 장치The raw material supply nozzle 130 is combined with each other at a predetermined portion near the free end of the coating liquid supply pipe 121 and the extract liquid supply pipe 111 to form a double tube. The extraction liquid supply pipe 111 penetrates the coating liquid supply pipe 121. Automated extract liquid encapsulation device having a structure in which a double tube is formed into and accommodated, and the free end of the extract liquid supply pipe 111 that is an inner tube extends longer than the coating liquid supply pipe 121 that is an outer tube. 삭제delete 제 2 항에 있어서, 원료공급노즐(130)은 내측관인 추출액공급관(111)의 자유단부가 외측관인 코팅액공급관(121)의 하단부보다 더 길게 형성함에 있어 그 길이차(h)가 길수록 액상의 코팅피막이 형성된 추출액 방울(g)의 형상이 물방울 또는 계란형을 이루고 짧을수록 구형(球形)에 가깝게 되는 추출액 캡슐화 자동화 장치The method of claim 2, wherein the raw material supply nozzle 130 is formed in the free end of the extraction liquid supply pipe 111 is the inner tube longer than the lower end of the coating liquid supply pipe 121 is the outer tube, the longer the difference (h) of the liquid coating Extraction capsule encapsulation automation device in which the droplet form (g) having a coating is formed in a drop or egg shape and becomes shorter as a sphere becomes shorter.
KR10-2001-0041734A 2001-07-11 2001-07-11 Extracting substance Capsulating Method and Equipment KR100431273B1 (en)

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JPS5955341A (en) * 1982-09-24 1984-03-30 Nippon Carbide Ind Co Ltd Production device for seamless packed capsule
JPS59112833A (en) * 1982-12-17 1984-06-29 Nippon Carbide Ind Co Ltd Apparatus for preparing seamless filled capsule
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