JPWO2021053555A5 - - Google Patents
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- Publication number
- JPWO2021053555A5 JPWO2021053555A5 JP2022516379A JP2022516379A JPWO2021053555A5 JP WO2021053555 A5 JPWO2021053555 A5 JP WO2021053555A5 JP 2022516379 A JP2022516379 A JP 2022516379A JP 2022516379 A JP2022516379 A JP 2022516379A JP WO2021053555 A5 JPWO2021053555 A5 JP WO2021053555A5
- Authority
- JP
- Japan
- Prior art keywords
- aryl
- alkyl
- carbocyclyl
- heteroatoms selected
- heteroaryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962901229P | 2019-09-16 | 2019-09-16 | |
| US62/901,229 | 2019-09-16 | ||
| PCT/IB2020/058641 WO2021053555A1 (en) | 2019-09-16 | 2020-09-16 | Glue degraders and methods of use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022548095A JP2022548095A (ja) | 2022-11-16 |
| JPWO2021053555A5 true JPWO2021053555A5 (pl) | 2023-09-21 |
Family
ID=72717893
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022516379A Pending JP2022548095A (ja) | 2019-09-16 | 2020-09-16 | 接着分解剤及びその使用方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20220363671A1 (pl) |
| EP (1) | EP4031243A1 (pl) |
| JP (1) | JP2022548095A (pl) |
| CN (1) | CN114401960A (pl) |
| WO (1) | WO2021053555A1 (pl) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11352350B2 (en) | 2018-11-30 | 2022-06-07 | Kymera Therapeutics, Inc. | IRAK degraders and uses thereof |
| BR112022011651A2 (pt) | 2019-12-17 | 2022-08-23 | Kymera Therapeutics Inc | Degradadores de irak e usos dos mesmos |
| EP4076524A4 (en) | 2019-12-17 | 2023-11-29 | Kymera Therapeutics, Inc. | IRAQ DEGRADERS AND USES THEREOF |
| TW202210483A (zh) | 2020-06-03 | 2022-03-16 | 美商凱麥拉醫療公司 | Irak降解劑之結晶型 |
| AU2021396308A1 (en) * | 2020-12-09 | 2023-06-22 | Kymera Therapeutics, Inc. | Irak degraders and uses thereof |
| CA3208313A1 (en) | 2021-01-13 | 2022-07-21 | Monte Rosa Therapeutics Ag | Isoindolinone compounds |
| WO2022153220A1 (en) | 2021-01-13 | 2022-07-21 | Monte Rosa Therapeutics Ag | Methods for the identification of degrons |
| EP4347860A1 (en) | 2021-06-04 | 2024-04-10 | Monte Rosa Therapeutics, Inc. | E3 ligase fusion proteins for proximity detection |
| WO2023091567A1 (en) | 2021-11-17 | 2023-05-25 | Monte Rosa Therapeutics, Inc. | Degron and neosubstrate identification |
| CN114410607A (zh) * | 2022-03-22 | 2022-04-29 | 上海威高医疗技术发展有限公司 | 嗜热羧酸酯酶突变体及其应用 |
| CN116804005A (zh) * | 2022-05-13 | 2023-09-26 | 上海湃隆生物科技有限公司 | 驱动蛋白kif18a抑制剂及其应用 |
| WO2024073871A1 (en) * | 2022-10-04 | 2024-04-11 | Biofront Ltd | Gspt1 degraders, compositions comprising the degrader, and methods of using the same |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5114946A (en) | 1987-06-12 | 1992-05-19 | American Cyanamid Company | Transdermal delivery of pharmaceuticals |
| US4818541A (en) | 1987-08-19 | 1989-04-04 | Schering Corporation | Transdermal delivery of enantiomers of phenylpropanolamine |
| CN110612294B (zh) * | 2017-01-31 | 2024-01-16 | 阿尔维纳斯运营股份有限公司 | 人小脑蛋白配体和包含其的双官能化合物 |
| EP3897631A4 (en) * | 2018-12-20 | 2022-11-23 | C4 Therapeutics, Inc. | TARGETED PROTEIN DEGRADATION |
-
2020
- 2020-09-16 WO PCT/IB2020/058641 patent/WO2021053555A1/en unknown
- 2020-09-16 EP EP20785841.6A patent/EP4031243A1/en active Pending
- 2020-09-16 JP JP2022516379A patent/JP2022548095A/ja active Pending
- 2020-09-16 US US17/642,292 patent/US20220363671A1/en active Pending
- 2020-09-16 CN CN202080063698.5A patent/CN114401960A/zh active Pending
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