JPS6485935A - Production of hydroxy compound - Google Patents
Production of hydroxy compoundInfo
- Publication number
- JPS6485935A JPS6485935A JP62245682A JP24568287A JPS6485935A JP S6485935 A JPS6485935 A JP S6485935A JP 62245682 A JP62245682 A JP 62245682A JP 24568287 A JP24568287 A JP 24568287A JP S6485935 A JPS6485935 A JP S6485935A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- tetrahydropyranyl
- catalyst
- protecting group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PURPOSE:To conduct the selective elimination of the protecting group from the title compound having hydroxyl groups protected with tetrahydropyranyl or silyl groups, by using a thermal condensate of a specific organotin compound with an alkyl phosphate as a catalyst. CONSTITUTION:Using, as a catalyst, a thermal condensate from a compound selected from formulas I-III (R is 1-12C alkyl, alkenyl, cycloalkyl, aryl, aralkyl which may be substituted; X is halogen, alkoxy, aryloxy, acyloxy, residue of partial phosphate ester; a is integer of 1-4; c=3/2 in b=1, c=1 in b=2; the compound of formula II may form a complex with the compound of formula III) and an alkyl phosphate, an organic compound containing a structural unit of the formula IV (Y is OH-protecting group such as tetrahydropyranyl or silyl), especially a compound sensitive to acid is deprotected selectively to liberate the subject hydroxyl compound in high efficiency.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62245682A JPH0617319B2 (en) | 1987-09-28 | 1987-09-28 | Method for producing hydroxy compound |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62245682A JPH0617319B2 (en) | 1987-09-28 | 1987-09-28 | Method for producing hydroxy compound |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS6485935A true JPS6485935A (en) | 1989-03-30 |
JPH0617319B2 JPH0617319B2 (en) | 1994-03-09 |
Family
ID=17137243
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP62245682A Expired - Fee Related JPH0617319B2 (en) | 1987-09-28 | 1987-09-28 | Method for producing hydroxy compound |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPH0617319B2 (en) |
-
1987
- 1987-09-28 JP JP62245682A patent/JPH0617319B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JPH0617319B2 (en) | 1994-03-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
LAPS | Cancellation because of no payment of annual fees |