JPS6485913A - Anti-inflammatory analgesic plaster containing 4-biphenylylacetic acid - Google Patents

Anti-inflammatory analgesic plaster containing 4-biphenylylacetic acid

Info

Publication number
JPS6485913A
JPS6485913A JP24338787A JP24338787A JPS6485913A JP S6485913 A JPS6485913 A JP S6485913A JP 24338787 A JP24338787 A JP 24338787A JP 24338787 A JP24338787 A JP 24338787A JP S6485913 A JPS6485913 A JP S6485913A
Authority
JP
Japan
Prior art keywords
compound
formula
base
inflammatory analgesic
dissolved
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP24338787A
Other languages
Japanese (ja)
Inventor
Akihiko Kusunoki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Saitama Daiichi Pharmaceutical Co Ltd
Original Assignee
Saitama Daiichi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Saitama Daiichi Pharmaceutical Co Ltd filed Critical Saitama Daiichi Pharmaceutical Co Ltd
Priority to JP24338787A priority Critical patent/JPS6485913A/en
Publication of JPS6485913A publication Critical patent/JPS6485913A/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PURPOSE:To provide an anti-inflammatory analgesic plaster containing 4- biphenylylacetic acid, exhibiting quantitative and durable action and free from side effect in transcutaneous administration. CONSTITUTION:The objective plaster contains the compound of formula as an active component. A base containing the compound of formula in dissolved state is spread over a surface of a sheet substrate such as cloth or paper to enable the transcutaneous administration. The compound of formula is dissolved in an alkaline aqueous solution (e.g. NaOH or KOH solution) added with a small amount of a water-soluble organic amine (e.g. diethanolamine or triethanolamine). The obtained solution is kneaded into a base and added with an acid (e.g. CHl or H2SO4) to adjust the pH to 6-7, preferably 6.4-6.8. The compound of formula can be uniformly dissolved in the base by this process without causing the precipitation of the compound with time. The amount of the compound of formula is preferably 0.1-5.0wt.%, especially 0.3-1wt.% based on the base.
JP24338787A 1987-09-26 1987-09-26 Anti-inflammatory analgesic plaster containing 4-biphenylylacetic acid Pending JPS6485913A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP24338787A JPS6485913A (en) 1987-09-26 1987-09-26 Anti-inflammatory analgesic plaster containing 4-biphenylylacetic acid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP24338787A JPS6485913A (en) 1987-09-26 1987-09-26 Anti-inflammatory analgesic plaster containing 4-biphenylylacetic acid

Publications (1)

Publication Number Publication Date
JPS6485913A true JPS6485913A (en) 1989-03-30

Family

ID=17103098

Family Applications (1)

Application Number Title Priority Date Filing Date
JP24338787A Pending JPS6485913A (en) 1987-09-26 1987-09-26 Anti-inflammatory analgesic plaster containing 4-biphenylylacetic acid

Country Status (1)

Country Link
JP (1) JPS6485913A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0436217A2 (en) * 1989-12-25 1991-07-10 LEDERLE (JAPAN), Ltd. Anti-inflammatory analgesic patch
EP1072261A3 (en) * 1999-07-30 2001-05-16 Hisamitsu Pharmaceutical Co., Inc. Felbinac-containing patch
JP2008069127A (en) * 2006-09-15 2008-03-27 Toko Yakuhin Kogyo Kk Anti-inflammatory and analgesic cream preparation and method for producing the same
KR100867262B1 (en) * 2007-01-17 2008-11-06 대화제약 주식회사 The composition of plaster containing felbinacs

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0436217A2 (en) * 1989-12-25 1991-07-10 LEDERLE (JAPAN), Ltd. Anti-inflammatory analgesic patch
EP1072261A3 (en) * 1999-07-30 2001-05-16 Hisamitsu Pharmaceutical Co., Inc. Felbinac-containing patch
JP2008069127A (en) * 2006-09-15 2008-03-27 Toko Yakuhin Kogyo Kk Anti-inflammatory and analgesic cream preparation and method for producing the same
KR100867262B1 (en) * 2007-01-17 2008-11-06 대화제약 주식회사 The composition of plaster containing felbinacs

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