JPS6447720A - Production of dried powder of earthworm - Google Patents

Production of dried powder of earthworm

Info

Publication number
JPS6447720A
JPS6447720A JP63094541A JP9454188A JPS6447720A JP S6447720 A JPS6447720 A JP S6447720A JP 63094541 A JP63094541 A JP 63094541A JP 9454188 A JP9454188 A JP 9454188A JP S6447720 A JPS6447720 A JP S6447720A
Authority
JP
Japan
Prior art keywords
dried powder
vomited
castings
freezing
hyperlipemia
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP63094541A
Other languages
Japanese (ja)
Other versions
JPH0788308B2 (en
Inventor
Yoichi Ishii
Hisashi Mihara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EIMEI KK
Eimei Co Ltd
Original Assignee
EIMEI KK
Eimei Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EIMEI KK, Eimei Co Ltd filed Critical EIMEI KK
Priority to JP63094541A priority Critical patent/JPH0788308B2/en
Priority to KR1019880007133A priority patent/KR930001983B1/en
Priority to US07/228,672 priority patent/US5024844A/en
Priority to DE3827623A priority patent/DE3827623C2/en
Priority to CA000575021A priority patent/CA1322956C/en
Priority to GB8819523A priority patent/GB2208602B/en
Priority to CN88106168A priority patent/CN1031653A/en
Priority to IT8919429A priority patent/IT1230719B/en
Priority to FR8901976A priority patent/FR2630008B1/en
Publication of JPS6447720A publication Critical patent/JPS6447720A/en
Priority to US07/641,519 priority patent/US5128148A/en
Publication of JPH0788308B2 publication Critical patent/JPH0788308B2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

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  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

PURPOSE:To obtain dried powder having excellently alleviating activity against hyperlipemia and safety, by grinding in a wet state live earthworm from which castings in digestive tube are vomited and dirt is cleaned and removed and freeze-drying prepared suspension. CONSTITUTION:Live earthworms are allowed to stand in an aqueous solution containing <=0.3wt.% organic acid, inorganic acid or Na salt thereof or in fresh water, castings in digestive tube are vomited, then dirt attached to silkworm is washed with water and removed or the operations are carried out in the reverse order. The silkworms are ground in a set state to give suspension, which is frozen at -10--60 deg.C. Freezing and vacuum drying are carried out in a temperature range of -60-80 deg.C at <=10mmHg degree of vacuum for 10-100hr while raising temperature stepwise and the final process of the freezing and vacuum drying are done at 70-80 deg.C at 0.01-0.5mmHg for 5-10hr to give dried powder. The powder is extremely useful as a preventive and remedy for hyperlipemia and arteriosclerosis and an improver for serum lipid metabolism.
JP63094541A 1987-08-18 1988-04-19 Method for manufacturing earthworm dry powder Expired - Lifetime JPH0788308B2 (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
JP63094541A JPH0788308B2 (en) 1988-04-19 1988-04-19 Method for manufacturing earthworm dry powder
KR1019880007133A KR930001983B1 (en) 1987-08-18 1988-06-14 Process for the production of dried earthworm powder
US07/228,672 US5024844A (en) 1987-08-18 1988-08-05 Process for the production of dried earthworm powder and antihyperlipemic, antidiabetic, antihypertensive and antihypotensive preparations containing dried earthworm powder as active ingredient
DE3827623A DE3827623C2 (en) 1987-08-18 1988-08-15 Process for the preparation of pharmaceutically usable dried earthworm powder and its use as an antihyperlipemic, anti-diabetic, antihypertensive and antihypotonic preparation
GB8819523A GB2208602B (en) 1987-08-18 1988-08-17 Process for the production of dried earthworm powder and antihyperlipemic,anti-diabetic,antihypertensive and antihypotensive preparations containing dried ear
CA000575021A CA1322956C (en) 1987-08-18 1988-08-17 Process for the production of dried earthworm powder and antihyperlipemic, antidiabetic, antihypertensive and antihypotensive preparations containing dried earthworm powder as active ingredient
CN88106168A CN1031653A (en) 1987-08-18 1988-08-18 Dry earthworm powder and contain the hyperlipidemia of dry earthworm powder as active component, anti-diabetic, the production method of the preparation of resisting hypertension and hypotension
IT8919429A IT1230719B (en) 1988-04-19 1989-02-14 PROCEDURE FOR THE PRODUCTION OF DRIED LUMBRIC POWDER AND PREPARATIONS ANTI HYPERLIPEMIC, DIABETIC ANTI, HYPERTENSIVE ANTI AND HYPOTHENSIVE ANTI CONTAINING, AS ACTIVE INGREDIENT, DRIED LUMBRIC POWDER.
FR8901976A FR2630008B1 (en) 1988-04-19 1989-02-15 DRIED EARTHWORM POWDER USEFUL AS A MEDICAMENT AND PROCESS FOR THE PREPARATION THEREOF
US07/641,519 US5128148A (en) 1987-08-18 1991-01-15 Process for the production of dried earthworm powder and antihyperlipemic, antidiabetic, antihypertensive and antihypotensive preparations containing dried earthworm powder as active ingredient

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP63094541A JPH0788308B2 (en) 1988-04-19 1988-04-19 Method for manufacturing earthworm dry powder

Publications (2)

Publication Number Publication Date
JPS6447720A true JPS6447720A (en) 1989-02-22
JPH0788308B2 JPH0788308B2 (en) 1995-09-27

Family

ID=14113177

Family Applications (1)

Application Number Title Priority Date Filing Date
JP63094541A Expired - Lifetime JPH0788308B2 (en) 1987-08-18 1988-04-19 Method for manufacturing earthworm dry powder

Country Status (1)

Country Link
JP (1) JPH0788308B2 (en)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004292402A (en) * 2003-03-28 2004-10-21 Mihara Lr Kenkyusho:Kk Method for producing dried earthworm powder
JP2007039404A (en) * 2005-08-05 2007-02-15 Kokan Yakuhin Kenkyusho:Kk Method for producing lumbrokinase-containing protein by automatic chromatography apparatus and application of the same protein
JP2008081476A (en) * 2006-09-29 2008-04-10 Ｗｅｌｌ Ｓｔｏｎｅ 有限会社 Method for producing dried powder of earthworm
EP2105139A1 (en) 2008-03-26 2009-09-30 Well Stone Co. Method of producing a dry earthworm powder
EP2316464A1 (en) 2009-10-13 2011-05-04 Well Stone Co. Method of producing a dry earthworm powder
US8137701B2 (en) 2008-03-21 2012-03-20 Well Stone Co. Method of producing a dry earthworm powder
WO2012073593A1 (en) 2011-04-11 2012-06-07 Ｗｅｌｌ Ｓｔｏｎｅ 有限会社 Manufacturing method for dried earthworm powder
JP2015048353A (en) * 2014-03-05 2015-03-16 ワキ製薬株式会社 Method for manufacturing earthworm dried powder
WO2018173971A1 (en) 2017-03-21 2018-09-27 Ｗｅｌｌ Ｓｔｏｎｅ 有限会社 Production method of nasal drop composition, and nasal drop composition
WO2018173972A1 (en) 2017-03-21 2018-09-27 Ｗｅｌｌ Ｓｔｏｎｅ 有限会社 Method for producing therapeutic agent for skin lesions, and therapeutic agent for skin lesions

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01304861A (en) * 1988-10-18 1989-12-08 Yoichi Ishii Production of dried powder of earthworm

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01304861A (en) * 1988-10-18 1989-12-08 Yoichi Ishii Production of dried powder of earthworm

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004292402A (en) * 2003-03-28 2004-10-21 Mihara Lr Kenkyusho:Kk Method for producing dried earthworm powder
JP2007039404A (en) * 2005-08-05 2007-02-15 Kokan Yakuhin Kenkyusho:Kk Method for producing lumbrokinase-containing protein by automatic chromatography apparatus and application of the same protein
JP2008081476A (en) * 2006-09-29 2008-04-10 Ｗｅｌｌ Ｓｔｏｎｅ 有限会社 Method for producing dried powder of earthworm
US8137701B2 (en) 2008-03-21 2012-03-20 Well Stone Co. Method of producing a dry earthworm powder
EP2105139A1 (en) 2008-03-26 2009-09-30 Well Stone Co. Method of producing a dry earthworm powder
EP2316464A1 (en) 2009-10-13 2011-05-04 Well Stone Co. Method of producing a dry earthworm powder
US8394417B2 (en) 2009-10-13 2013-03-12 Well Stone Co. Method of producing a dry earthworm powder
WO2012073593A1 (en) 2011-04-11 2012-06-07 Ｗｅｌｌ Ｓｔｏｎｅ 有限会社 Manufacturing method for dried earthworm powder
US9511098B2 (en) 2011-04-11 2016-12-06 Well Stone Co. Method for producing dry earthworm powder
JP2015048353A (en) * 2014-03-05 2015-03-16 ワキ製薬株式会社 Method for manufacturing earthworm dried powder
WO2018173971A1 (en) 2017-03-21 2018-09-27 Ｗｅｌｌ Ｓｔｏｎｅ 有限会社 Production method of nasal drop composition, and nasal drop composition
WO2018173972A1 (en) 2017-03-21 2018-09-27 Ｗｅｌｌ Ｓｔｏｎｅ 有限会社 Method for producing therapeutic agent for skin lesions, and therapeutic agent for skin lesions

Also Published As

Publication number Publication date
JPH0788308B2 (en) 1995-09-27

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