JPS6431752A - Amide derivative and skin external preparation containing said derivative - Google Patents

Amide derivative and skin external preparation containing said derivative

Info

Publication number
JPS6431752A
JPS6431752A JP18723487A JP18723487A JPS6431752A JP S6431752 A JPS6431752 A JP S6431752A JP 18723487 A JP18723487 A JP 18723487A JP 18723487 A JP18723487 A JP 18723487A JP S6431752 A JPS6431752 A JP S6431752A
Authority
JP
Japan
Prior art keywords
compound shown
formula
derivative
hydrocarbon group
external preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP18723487A
Other languages
Japanese (ja)
Other versions
JPH078844B2 (en
Inventor
Akira Kawamata
Shinji Yano
Shinji Yamada
Shuichi Akasaki
Naotake Takaishi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kao Corp
Original Assignee
Kao Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kao Corp filed Critical Kao Corp
Priority to JP62187234A priority Critical patent/JPH078844B2/en
Publication of JPS6431752A publication Critical patent/JPS6431752A/en
Publication of JPH078844B2 publication Critical patent/JPH078844B2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/68—Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

NEW MATERIAL:A compound shown by formula I (R<1> is 10-26C hydrocarbon group; R<2> is 9-25C hydrocarbon group; X and Y are H, 1-4C hydrocarbon group, acryl or aralkyl and are not H at the same time). EXAMPLE:N-(3-Hexadesyloxy-2-hydroxypropyl)-N-2-methylethylhexadecanamide. USE:A skin external preparation showing excellent improving and preventing effects chapped skin. PREPARATION:Amino group of a compound shown by formula II obtained from glycidyl ether and an ethanolamine derivative according to the reaction formula is selectively acylated to give a compound shown by formula III. Hydroxyl group of the compound shown by formula III is reacted with an alkyl halide such as methyl iodine in the presence of a basic catalyst (e.g. pyridine) to give a compound shown by formula I.
JP62187234A 1987-07-27 1987-07-27 Amide derivative and external preparation for skin containing the same Expired - Fee Related JPH078844B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP62187234A JPH078844B2 (en) 1987-07-27 1987-07-27 Amide derivative and external preparation for skin containing the same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62187234A JPH078844B2 (en) 1987-07-27 1987-07-27 Amide derivative and external preparation for skin containing the same

Publications (2)

Publication Number Publication Date
JPS6431752A true JPS6431752A (en) 1989-02-02
JPH078844B2 JPH078844B2 (en) 1995-02-01

Family

ID=16202404

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62187234A Expired - Fee Related JPH078844B2 (en) 1987-07-27 1987-07-27 Amide derivative and external preparation for skin containing the same

Country Status (1)

Country Link
JP (1) JPH078844B2 (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5446027A (en) * 1992-11-02 1995-08-29 Kao Corporation Amide derivative and external skin care preparation containing the same
JPH09165313A (en) * 1995-12-15 1997-06-24 Kao Corp Skin preparation for external use
US6468251B1 (en) 1997-10-23 2002-10-22 Jims Co., Ltd. Mixing/charging port for medical treatment
WO2018221602A1 (en) 2017-05-30 2018-12-06 花王株式会社 Water-in-oil emulsion composition
WO2018221603A1 (en) 2017-05-30 2018-12-06 花王株式会社 Water-in-oil emulsion composition
WO2019131987A1 (en) 2017-12-28 2019-07-04 花王株式会社 Lipid particle dispersion

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62215553A (en) * 1986-03-18 1987-09-22 Kao Corp Glycerol derivative and pharmaceutical preparation containing same
JPS63218609A (en) * 1987-03-09 1988-09-12 Kao Corp External drug for skin
JPS63227514A (en) * 1987-03-16 1988-09-21 Kao Corp Dermatic drug for external application
JPS63227513A (en) * 1987-03-16 1988-09-21 Kao Corp Dermatic drug for external application
JPS6429347A (en) * 1987-07-24 1989-01-31 Kao Corp Amide derivative and external agent for skin containing said derivative

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62215553A (en) * 1986-03-18 1987-09-22 Kao Corp Glycerol derivative and pharmaceutical preparation containing same
JPS63218609A (en) * 1987-03-09 1988-09-12 Kao Corp External drug for skin
JPS63227514A (en) * 1987-03-16 1988-09-21 Kao Corp Dermatic drug for external application
JPS63227513A (en) * 1987-03-16 1988-09-21 Kao Corp Dermatic drug for external application
JPS6429347A (en) * 1987-07-24 1989-01-31 Kao Corp Amide derivative and external agent for skin containing said derivative

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5446027A (en) * 1992-11-02 1995-08-29 Kao Corporation Amide derivative and external skin care preparation containing the same
JPH09165313A (en) * 1995-12-15 1997-06-24 Kao Corp Skin preparation for external use
US6468251B1 (en) 1997-10-23 2002-10-22 Jims Co., Ltd. Mixing/charging port for medical treatment
WO2018221602A1 (en) 2017-05-30 2018-12-06 花王株式会社 Water-in-oil emulsion composition
WO2018221603A1 (en) 2017-05-30 2018-12-06 花王株式会社 Water-in-oil emulsion composition
WO2019131987A1 (en) 2017-12-28 2019-07-04 花王株式会社 Lipid particle dispersion

Also Published As

Publication number Publication date
JPH078844B2 (en) 1995-02-01

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Legal Events

Date Code Title Description
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LAPS Cancellation because of no payment of annual fees