JPS643172A - Cycloheptimidazole derivative - Google Patents

Cycloheptimidazole derivative

Info

Publication number
JPS643172A
JPS643172A JP15731687A JP15731687A JPS643172A JP S643172 A JPS643172 A JP S643172A JP 15731687 A JP15731687 A JP 15731687A JP 15731687 A JP15731687 A JP 15731687A JP S643172 A JPS643172 A JP S643172A
Authority
JP
Japan
Prior art keywords
formula
ncq
methoxyphenyl
react
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP15731687A
Other languages
Japanese (ja)
Other versions
JPH013172A (en
Inventor
Ikuo Ueda
Masaaki Matsuo
Kiyoshi Taniguchi
Shinji Shigenaga
Takatomo Ogawara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Priority to JP62-157316A priority Critical patent/JPH013172A/en
Priority claimed from JP62-157316A external-priority patent/JPH013172A/en
Publication of JPS643172A publication Critical patent/JPS643172A/en
Publication of JPH013172A publication Critical patent/JPH013172A/en
Pending legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

NEW MATERIAL:A compound of formula I [R1 is H, lower alkyl, cycloalkyl, aryl which may be substituted, heterocyclic group which may be substituted; R2 is R1 except H atom] and its salt.
EXAMPLE: 1, 2-Dihydro-1-( 4-methoxyphenyl )-2-( 4-methoxyphenyl )cyclo-heptimida zole hydrochloride.
USE: Medicines. Anti-inflammatory or analgesic.
PREPARATION: For example, an isocyanate or isothiocyanate of the formula: R1NCQ1 (Q1 is O, S) or R2NCQ1 is allowed to react with an amine of the formu la NH2-R1 or NH2-R2 to form a urea or thiourea of formula IV. The product is subjected to dehydration or dehydrosulfidization to give a novel carbodiimide derivative of formula II, and the product is allowed to react with 2-aminotropon of formula III in the absence or presence of an anhydrous solvent such as tolu ene at room temperature or under heating to effect dehydrative condensation reaction to give the compound of formula I.
COPYRIGHT: (C)1989,JPO&Japio
JP62-157316A 1987-06-24 Cycloheptoimidazole derivatives Pending JPH013172A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP62-157316A JPH013172A (en) 1987-06-24 Cycloheptoimidazole derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62-157316A JPH013172A (en) 1987-06-24 Cycloheptoimidazole derivatives

Publications (2)

Publication Number Publication Date
JPS643172A true JPS643172A (en) 1989-01-06
JPH013172A JPH013172A (en) 1989-01-06

Family

ID=

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4949097A (en) * 1988-06-10 1990-08-14 Minolta Camera Kabushiki Kaisha Thermal printer
US8420634B2 (en) 2007-09-24 2013-04-16 Rottapharm S.P.A. Amidine, thiourea and guanidine derivatives of 2-aminobenzothiazoles and aminobenzothiazines for their use as pharmacological agents for the treatment of neurodegenerative pathologies

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4949097A (en) * 1988-06-10 1990-08-14 Minolta Camera Kabushiki Kaisha Thermal printer
US8420634B2 (en) 2007-09-24 2013-04-16 Rottapharm S.P.A. Amidine, thiourea and guanidine derivatives of 2-aminobenzothiazoles and aminobenzothiazines for their use as pharmacological agents for the treatment of neurodegenerative pathologies

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