JPS6426559A - Novel phthalide derivative - Google Patents

Novel phthalide derivative

Info

Publication number
JPS6426559A
JPS6426559A JP18222787A JP18222787A JPS6426559A JP S6426559 A JPS6426559 A JP S6426559A JP 18222787 A JP18222787 A JP 18222787A JP 18222787 A JP18222787 A JP 18222787A JP S6426559 A JPS6426559 A JP S6426559A
Authority
JP
Japan
Prior art keywords
formula
compound shown
give
alkyl
methoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP18222787A
Other languages
Japanese (ja)
Other versions
JP2621194B2 (en
Inventor
Yoshimitsu Ogawa
Kunio Hosaka
Kiyoshi Kubota
Hisanori Satomi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tsumura and Co
Original Assignee
Tsumura and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tsumura and Co filed Critical Tsumura and Co
Priority to JP62182227A priority Critical patent/JP2621194B2/en
Publication of JPS6426559A publication Critical patent/JPS6426559A/en
Application granted granted Critical
Publication of JP2621194B2 publication Critical patent/JP2621194B2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

NEW MATERIAL:A compound shown by shown by formula I [R1 and R2 are H, OH or methoxy; R3 and R4 are H or methoxy; R<5> is alkyl; R<6> is H, alkyl or group shown by formula II (R<7> is methyl or phenyl)]. EXAMPLE:3-Butyl-2-ethylphthalimidine. USE:A drug having lowering action on blood viscosity. PREPARATION:A compound shown by formula III is treated with an alkyl halide in the presence of a base to give a compound shown by formula IV, which is hydrolyzed to give a compound shown by formula V, which is converted into a methyl ester and the methyl ester is brominated at the benzyl position to give a compound shown by formula VI, which is reacted with a compound shown by the formula X-NH2 (X is H or alkyl) to give a compound shown by formula I.
JP62182227A 1987-07-23 1987-07-23 New phthalide derivatives Expired - Lifetime JP2621194B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP62182227A JP2621194B2 (en) 1987-07-23 1987-07-23 New phthalide derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62182227A JP2621194B2 (en) 1987-07-23 1987-07-23 New phthalide derivatives

Publications (2)

Publication Number Publication Date
JPS6426559A true JPS6426559A (en) 1989-01-27
JP2621194B2 JP2621194B2 (en) 1997-06-18

Family

ID=16114566

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62182227A Expired - Lifetime JP2621194B2 (en) 1987-07-23 1987-07-23 New phthalide derivatives

Country Status (1)

Country Link
JP (1) JP2621194B2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103655555A (en) * 2012-09-14 2014-03-26 中山大学 Application of 3-n-isoindoline-1-ketone in preparation of medicament for preventing and treating cerebral infarction

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS50154293A (en) * 1974-05-15 1975-12-12
JPS62190162A (en) * 1986-02-18 1987-08-20 Asahi Glass Co Ltd Optically active lactam compound and liquid crystal composition using said compound

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS50154293A (en) * 1974-05-15 1975-12-12
JPS62190162A (en) * 1986-02-18 1987-08-20 Asahi Glass Co Ltd Optically active lactam compound and liquid crystal composition using said compound

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103655555A (en) * 2012-09-14 2014-03-26 中山大学 Application of 3-n-isoindoline-1-ketone in preparation of medicament for preventing and treating cerebral infarction

Also Published As

Publication number Publication date
JP2621194B2 (en) 1997-06-18

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