JPS6426537A - Production of dibenzyls - Google Patents
Production of dibenzylsInfo
- Publication number
- JPS6426537A JPS6426537A JP18444787A JP18444787A JPS6426537A JP S6426537 A JPS6426537 A JP S6426537A JP 18444787 A JP18444787 A JP 18444787A JP 18444787 A JP18444787 A JP 18444787A JP S6426537 A JPS6426537 A JP S6426537A
- Authority
- JP
- Japan
- Prior art keywords
- medicines
- metal hydroxide
- dispersed
- alkaline metal
- mixed solvent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PURPOSE:To industrially and readily obtain dibenzyls useful as an intermediate for medicines in high yield, by oxidatively condensing a nitro group-substituted toluene based compound using a finely powdered alkaline metal hydroxide dispersed in a specific mixed solvent. CONSTITUTION:A nitro group-substituted toluene based compound, such as 2-nitrotoluene or 2-nitro-4-chlorotoluene, is oxidatively condensed using an alkaline metal hydroxide, such as NaOH, finely powdered and dispersed in a mixed solvent of an inert solvent selected from paraffinic hydrocarbons, such as paraffinic, isoparaffinic or cycloparaffinic hydrocarbons, e.g. n-decane, and ethers having 50-300 deg.C boiling point and alcohols, such as tertiary butyl alcohol or tertiary amyl alcohol, at 20:80-80:20% mixing ratio of -20-+30 deg.C by passing air or O2 therethrough to afford the aimed compound useful as an intermediate for medicines, such as psychotic therapeutic or local anesthetic agent.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP18444787A JPS6426537A (en) | 1987-07-22 | 1987-07-22 | Production of dibenzyls |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP18444787A JPS6426537A (en) | 1987-07-22 | 1987-07-22 | Production of dibenzyls |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS6426537A true JPS6426537A (en) | 1989-01-27 |
Family
ID=16153306
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP18444787A Pending JPS6426537A (en) | 1987-07-22 | 1987-07-22 | Production of dibenzyls |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6426537A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8668925B2 (en) | 2003-12-12 | 2014-03-11 | Bayer Intellectual Property Gmbh | Transdermal delivery of hormones without the need of penetration enhancers |
-
1987
- 1987-07-22 JP JP18444787A patent/JPS6426537A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8668925B2 (en) | 2003-12-12 | 2014-03-11 | Bayer Intellectual Property Gmbh | Transdermal delivery of hormones without the need of penetration enhancers |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JPS6426537A (en) | Production of dibenzyls | |
JPS5229048A (en) | Lateral elevator | |
JPS5312825A (en) | Preparation of cresol | |
JPS51122055A (en) | A process for isolating 7- dehydtocholesterol | |
JPS56147749A (en) | Preparation of succinosuccinic acid dialkyl ester | |
JPS53127506A (en) | Stabilizer for mixed fuels | |
DK0474668T3 (en) | Conversion of a delta-16 steroid to a delta-17 (20) -20 silyl ether | |
JPS5293762A (en) | Preparation of cyclic ethers | |
JPS5344528A (en) | Separation of dihalogenobenzenes | |
JPS51151739A (en) | Method for mixing polymer and additives | |
JPS5398923A (en) | Preparation of hydroxyacetic acid | |
JPS541364A (en) | Purification of crude polyalkylene oxide | |
JPS5344505A (en) | Isomerization of alkene-3-ol-1 | |
JPS5278839A (en) | Purification of 2, 3-xylidine | |
JPS5331631A (en) | Preparation of alkoxyaromatic hydrocarbons | |
JPS5434619A (en) | Character picture receiving device | |
JPS53132508A (en) | Preparation of ethylene glycol | |
JPS5531839A (en) | Dispersant for organic rigment | |
JPS52111550A (en) | Preparation of dinitroanthraquinone | |
JPS543050A (en) | Separation of tetranitromethane | |
JPS5379848A (en) | Preparation of vitamine k1, k2 | |
JPS548700A (en) | Preparation of unsaturated polyethylene-imine | |
JPS5479297A (en) | Pyrazoquinoline | |
JPS5210203A (en) | Process for preparation of isoprene | |
JPS51140277A (en) | Gas separator |