JPS6415649A - Apparatus for detecting activity lowering state of immobilized enzyme membrane in biosensor - Google Patents
Apparatus for detecting activity lowering state of immobilized enzyme membrane in biosensorInfo
- Publication number
- JPS6415649A JPS6415649A JP62171967A JP17196787A JPS6415649A JP S6415649 A JPS6415649 A JP S6415649A JP 62171967 A JP62171967 A JP 62171967A JP 17196787 A JP17196787 A JP 17196787A JP S6415649 A JPS6415649 A JP S6415649A
- Authority
- JP
- Japan
- Prior art keywords
- current
- input terminal
- reversal input
- biosensor
- immobilized enzyme
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
PURPOSE:To detect the activity lowering state of an immobilized enzyme membrane, in a biosensor wherein a physiologically active substance is immobilized in the surfaces of substrate electrodes, by providing a current detecting means for detecting the supply current between the substrate electrodes at the time of non-measurement. CONSTITUTION:A current-voltage converting resistor 10 is connected to a current-voltage converting operational amplifier 9 and a diode 11 is connected between a reversal input terminal 9a and a non-reversal input terminal 9b. The reversal input terminal 9a is connected to an acting electrode 2 and an opposed electrode 3 is connected to an inverse bias supply terminal 12 through a resistor 13. The output from the constant voltage source 6 is divided to be connected to the non-reversal input terminal to constitute a bias supply circuit. By connecting an output terminal 9c to a concn. measuring operation part 24 and an active state discriminating comparing circuit 23 through a change-over switch 22, an active state can be discriminated from the current flowing between forwardly biased electrodes by the comparing circuit.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62171967A JPS6415649A (en) | 1987-07-09 | 1987-07-09 | Apparatus for detecting activity lowering state of immobilized enzyme membrane in biosensor |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62171967A JPS6415649A (en) | 1987-07-09 | 1987-07-09 | Apparatus for detecting activity lowering state of immobilized enzyme membrane in biosensor |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS6415649A true JPS6415649A (en) | 1989-01-19 |
Family
ID=15933076
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP62171967A Pending JPS6415649A (en) | 1987-07-09 | 1987-07-09 | Apparatus for detecting activity lowering state of immobilized enzyme membrane in biosensor |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6415649A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5377744A (en) * | 1990-06-28 | 1995-01-03 | Holton Machinery Limited | Method and device for continuous casting and extrusion |
WO2001071329A1 (en) * | 2000-03-22 | 2001-09-27 | All Medicus Co., Ltd. | Electrochemical biosensor readout meter |
-
1987
- 1987-07-09 JP JP62171967A patent/JPS6415649A/en active Pending
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5377744A (en) * | 1990-06-28 | 1995-01-03 | Holton Machinery Limited | Method and device for continuous casting and extrusion |
WO2001071329A1 (en) * | 2000-03-22 | 2001-09-27 | All Medicus Co., Ltd. | Electrochemical biosensor readout meter |
US6936146B2 (en) | 2000-03-22 | 2005-08-30 | Allmedicus Co., Ltd | Electrochemical biosensor readout meter |
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