JPS6331654A - Implant for artificial dental root and its production - Google Patents
Implant for artificial dental root and its productionInfo
- Publication number
- JPS6331654A JPS6331654A JP61172867A JP17286786A JPS6331654A JP S6331654 A JPS6331654 A JP S6331654A JP 61172867 A JP61172867 A JP 61172867A JP 17286786 A JP17286786 A JP 17286786A JP S6331654 A JPS6331654 A JP S6331654A
- Authority
- JP
- Japan
- Prior art keywords
- implant
- weight
- glass
- hydroxyapatite
- artificial tooth
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000007943 implant Substances 0.000 title claims description 36
- 238000004519 manufacturing process Methods 0.000 title claims description 5
- 210000004746 tooth root Anatomy 0.000 title 1
- 239000011521 glass Substances 0.000 claims description 35
- 229910052588 hydroxylapatite Inorganic materials 0.000 claims description 21
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 claims description 21
- 239000011162 core material Substances 0.000 claims description 18
- 239000000919 ceramic Substances 0.000 claims description 13
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims description 13
- 229910052751 metal Inorganic materials 0.000 claims description 10
- 239000002184 metal Substances 0.000 claims description 10
- 238000000034 method Methods 0.000 claims description 7
- 239000000203 mixture Substances 0.000 claims description 6
- 238000010304 firing Methods 0.000 claims description 3
- 210000000988 bone and bone Anatomy 0.000 description 12
- 239000000463 material Substances 0.000 description 10
- 229910010293 ceramic material Inorganic materials 0.000 description 7
- 239000007769 metal material Substances 0.000 description 7
- 239000005312 bioglass Substances 0.000 description 5
- 239000002245 particle Substances 0.000 description 5
- 239000000843 powder Substances 0.000 description 5
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 4
- 229910052586 apatite Inorganic materials 0.000 description 4
- -1 artificial organs Substances 0.000 description 4
- VSIIXMUUUJUKCM-UHFFFAOYSA-D pentacalcium;fluoride;triphosphate Chemical compound [F-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O VSIIXMUUUJUKCM-UHFFFAOYSA-D 0.000 description 4
- 238000007751 thermal spraying Methods 0.000 description 4
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 3
- NJPPVKZQTLUDBO-UHFFFAOYSA-N novaluron Chemical compound C1=C(Cl)C(OC(F)(F)C(OC(F)(F)F)F)=CC=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F NJPPVKZQTLUDBO-UHFFFAOYSA-N 0.000 description 3
- 239000011148 porous material Substances 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 238000001308 synthesis method Methods 0.000 description 3
- 229910052719 titanium Inorganic materials 0.000 description 3
- 239000010936 titanium Substances 0.000 description 3
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 2
- MCMNRKCIXSYSNV-UHFFFAOYSA-N Zirconium dioxide Chemical compound O=[Zr]=O MCMNRKCIXSYSNV-UHFFFAOYSA-N 0.000 description 2
- 239000000788 chromium alloy Substances 0.000 description 2
- 239000011248 coating agent Substances 0.000 description 2
- 238000000576 coating method Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000011737 fluorine Substances 0.000 description 2
- 229910052731 fluorine Inorganic materials 0.000 description 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 2
- 150000002500 ions Chemical class 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 229910001220 stainless steel Inorganic materials 0.000 description 2
- 239000010935 stainless steel Substances 0.000 description 2
- 238000001356 surgical procedure Methods 0.000 description 2
- 229910052715 tantalum Inorganic materials 0.000 description 2
- GUVRBAGPIYLISA-UHFFFAOYSA-N tantalum atom Chemical compound [Ta] GUVRBAGPIYLISA-UHFFFAOYSA-N 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 description 1
- CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 229910004298 SiO 2 Inorganic materials 0.000 description 1
- 241000251539 Vertebrata <Metazoa> Species 0.000 description 1
- 229910045601 alloy Inorganic materials 0.000 description 1
- 239000000956 alloy Substances 0.000 description 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 239000002473 artificial blood Substances 0.000 description 1
- 239000012237 artificial material Substances 0.000 description 1
- 238000005452 bending Methods 0.000 description 1
- 239000012620 biological material Substances 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 239000007767 bonding agent Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- FUFJGUQYACFECW-UHFFFAOYSA-L calcium hydrogenphosphate Chemical compound [Ca+2].OP([O-])([O-])=O FUFJGUQYACFECW-UHFFFAOYSA-L 0.000 description 1
- 239000001506 calcium phosphate Substances 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 235000019700 dicalcium phosphate Nutrition 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 238000005342 ion exchange Methods 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 239000011812 mixed powder Substances 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 210000004409 osteocyte Anatomy 0.000 description 1
- TWNQGVIAIRXVLR-UHFFFAOYSA-N oxo(oxoalumanyloxy)alumane Chemical compound O=[Al]O[Al]=O TWNQGVIAIRXVLR-UHFFFAOYSA-N 0.000 description 1
- 238000005245 sintering Methods 0.000 description 1
- 229920003002 synthetic resin Polymers 0.000 description 1
- 239000000057 synthetic resin Substances 0.000 description 1
- 235000019731 tricalcium phosphate Nutrition 0.000 description 1
- 229940078499 tricalcium phosphate Drugs 0.000 description 1
- 229910000391 tricalcium phosphate Inorganic materials 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Abstract
(57)【要約】本公報は電子出願前の出願データであるた
め要約のデータは記録されません。(57) [Abstract] This bulletin contains application data before electronic filing, so abstract data is not recorded.
Description
【発明の詳細な説明】
産業上の利用分野
本発明は人工歯根用インプラント及びその製造方法に関
するものである。さらに詳しくいえば、本発明は、生体
に対して優れた親和ａ２有し、長期間にわたって使用し
ても脱落することがない上に、機械的強度に優れた人工
歯根用インプラント、及びその製造方法に関するもので
ある。DETAILED DESCRIPTION OF THE INVENTION Field of Industrial Application The present invention relates to an artificial tooth root implant and a method for manufacturing the same. More specifically, the present invention provides an artificial tooth root implant that has excellent affinity a2 for living organisms, does not fall off even after long-term use, and has excellent mechanical strength, and a method for manufacturing the same. It is related to.
従来の技術
近年、医療技術のめざましい発展に伴い、人工臓器、人
工血管、人工関節、人工骨、人工歯根などの人工材料を
生体に挿入し、置換して失われた生体の一部や機能全回
復させるいわゆるインプラントロジーが脚光をあびてい
る。Conventional technology In recent years, with the remarkable development of medical technology, artificial materials such as artificial organs, artificial blood vessels, artificial joints, artificial bones, and artificial tooth roots are inserted into living organisms to replace parts of the living body that have been lost or to completely remove lost functions. So-called implantology, which helps people recover, is in the spotlight.
特に、歯科治療においては、歯根を除去した跡に人工歯
を入れる場合、骨と人工歯とを固定するための人工歯根
が積極的に利用されている。Particularly in dental treatment, when an artificial tooth is inserted into the area where a tooth root has been removed, an artificial tooth root is actively used to fix the artificial tooth to the bone.
従来、この人工歯根の材料としては、チタンやタンタル
、あるいはコバルト−クロム系合金、ステンレス鋼など
の金属材料や、単結晶体、多結晶体、多孔質体のアルミ
ナ材料などが知られている。Conventionally, known materials for artificial tooth roots include metal materials such as titanium, tantalum, cobalt-chromium alloys, and stainless steel, as well as single crystal, polycrystal, and porous alumina materials.
しかしながら、前者の金属材料は生体組織との親和性に
劣るために、長期間にわたって使用していると、脱落す
るのを免れない上に、溶出イオンにより、生体を害する
恐れがある。一方、該アルミナ材料は生体中でほとんど
化学変化を起こさず。However, since the former metal material has poor affinity with living tissue, if it is used for a long period of time, it will inevitably fall off, and the eluted ions may harm the living body. On the other hand, the alumina material undergoes almost no chemical changes in living organisms.
長期間にわたって安定で、生体に対して無害である上に
、生体製和性も比鮫的よいが、生体組織と化学結合を形
成することがなく、十分に満足しうる材料と・ヰいえな
い。It is stable over a long period of time, is harmless to living organisms, and has comparatively good biocompatibility, but it does not form chemical bonds with living tissues, so it cannot be called a fully satisfactory material. .
そこで、最近、骨や歯の組成と近似し、優れた生体親和
性含有する材料として、リン酸三カルシウムや水酸アパ
タイトなどが注目され、これらの材料を用いて人工歯根
を調製することが提案されている（例えば特開昭５６−
５４８１号公報参照）。Therefore, recently, tricalcium phosphate and hydroxyapatite have attracted attention as materials that have excellent biocompatibility and have compositions similar to those of bones and teeth, and it has been proposed to prepare artificial tooth roots using these materials. (For example, Japanese Patent Application Laid-Open No. 1983-
(See Publication No. 5481).
これらの材料は、生体に対して無害であり、かつ生体親
和性に優れる上に、自然骨と強く結合するという特徴を
有している。These materials are harmless to living organisms, have excellent biocompatibility, and have the characteristics of strongly bonding to natural bone.
また、骨組織と親和性のよいガラス、いわゆるバイオガ
ラスが生体材料として注目され、例えばこのものとメタ
クリレート系合成樹脂とから成る骨外科又は歯外科用結
合剤が提案されている（％閤昭５１−９８７５４号公報
）。このバイオガラスはＳｉＯ２−Ｎａ２０系ガラスや
ＳｉＯ２−Ｎａ２０−に２０−ＭｇＯ系ガラスに多量の
ＣａＯとＰ２Ｏ５を含有させたものであり、生体に対し
て無害であり、かつ生体親和性が良い上に、自然骨と強
く結合するという性質を肩している。これは、生体内に
おいて、該ガラス表面に水酸アパタイトが形成されるた
めである。In addition, glass with good affinity for bone tissue, so-called bioglass, has attracted attention as a biomaterial, and for example, a bonding agent for bone surgery or dental surgery consisting of this glass and a methacrylate-based synthetic resin has been proposed. -98754). This bioglass is made of SiO2-Na20-based glass or SiO2-Na20-20-MgO-based glass containing a large amount of CaO and P2O5, and is harmless to living organisms and has good biocompatibility. , which has the property of strongly bonding with natural bone. This is because hydroxyapatite is formed on the glass surface in vivo.
これらのアパタイト材料やバイオガラス材料は、前記し
たように、生体に対して無害でかつ親和性に優れ、しか
も自然骨と強く結合するという優れた特徴含有するが、
チタンなどの金属材料やアルミナなどのセラミックス材
料に比べて強度が劣シ、それらから形成される人工歯根
は強い衝隼や圧力が加えられると破損する恐れがあると
いう欠点を有している。As mentioned above, these apatite materials and bioglass materials have the excellent characteristics of being harmless to living organisms, having excellent affinity, and bonding strongly with natural bone.
They have the disadvantage that they are inferior in strength to metal materials such as titanium or ceramic materials such as alumina, and that artificial tooth roots formed from these materials may break if strong impact or pressure is applied.
このような欠点を改良したものとして１例えばセラミッ
クス製インプラント芯材の外周に、水酸アパタイトの末
の溶射層、セラミックス粉末と水酸アパタイト粉末との
混合粉末の溶射層、又はセラミックス粉末の溶射層、次
いで水酸アパタイト粉末の溶射層含有するインプラント
が提案されている（特公昭５９−．１６９１１号公報）
。To improve these defects, 1. For example, on the outer periphery of a ceramic implant core material, a thermally sprayed layer of hydroxyapatite powder, a thermally sprayed layer of a mixed powder of ceramic powder and hydroxyapatite powder, or a thermally sprayed layer of ceramic powder Then, an implant containing a sprayed layer of hydroxyapatite powder has been proposed (Japanese Patent Publication No. 16911/1983).
.
しかしながら、このインプラントは芯材としてセラミッ
クス材料を用い、かつその外周に溶射法によって水酸ア
パタイトなどの層を設ける方法で作成されるため、細く
て高強度の人工歯根用インプラントが得にくく、用途の
制限を免れない上に、特殊な溶射装置を必要とするなど
の問題を有している。However, because this implant uses a ceramic material as the core material and a layer of hydroxyapatite or the like is applied to the outer periphery by thermal spraying, it is difficult to obtain a thin, high-strength implant for artificial tooth roots, and the application is limited. In addition to being subject to limitations, there are other problems such as the need for special thermal spraying equipment.
発明が解決しようとする問題点
本発明の目的は、金属製又はセラミックス製インプラン
ト芯材の表面に水酸アバタイＩｆ主体とする多孔質層を
設けた、生体親和性及び機械的強度に優れる人工歯根用
インプラントを、溶射装置を用いず、かつ細い形状のも
のでも容易に製造しうる方法でもって提供することにあ
る。Problems to be Solved by the Invention The object of the present invention is to provide an artificial tooth root with excellent biocompatibility and mechanical strength, which has a porous layer mainly composed of hydroxyl abutite If on the surface of a metal or ceramic implant core material. An object of the present invention is to provide a method for easily manufacturing implants, even those having a thin shape, without using a thermal spraying device.
問題点を解決するための手段
本発明者らは鋭意研究を重ねた結果、ある種のガラスが
生体親和性に優れていることに着目し、水酸アパタイト
粉末と該ガラス成分との混合べ一ヌトヲ、金属製又はセ
ラミックス製インプラント芯材の表面に塗布し、焼成す
ることにより、前記目的を達成しうることを見出し、こ
の知見に基づいて本発明を完成するに至った。Means for Solving the Problems As a result of intensive research, the present inventors focused on the fact that a certain type of glass has excellent biocompatibility, and developed a mixture base of hydroxyapatite powder and the glass component. The inventors have discovered that the above object can be achieved by coating Nutowo on the surface of a metal or ceramic implant core material and firing it, and based on this knowledge, the present invention has been completed.
すなわち、本発明は、金ｆｉｆｆインプラント又はセラ
ミックス製インプラントの芯材の表面に、水酸アパタイ
トとガラスとから成る多孔質層全段けたことを特徴とす
る人工歯根用インブランを提供するものでちり、このも
のは、金属製インプラント又はセラミックス製インプラ
ントの芯材の表面に、水酸アパタイト粉末とガラス成分
との混合ベースｈ’６塗布し、次いで焼成して該表面に
水酸アパタイトとガ°ラスとから成る多孔質層を設ける
ことによって、製造することができる。That is, the present invention provides an implant for an artificial tooth root characterized in that a porous layer consisting of hydroxyapatite and glass is completely disposed on the surface of the core material of a gold Fiff implant or a ceramic implant. In this method, a mixed base h'6 of hydroxyapatite powder and a glass component is applied to the surface of the core material of a metal implant or a ceramic implant, and then fired to coat the surface with hydroxyapatite and glass. It can be manufactured by providing a porous layer consisting of.
本発明インプラントにおいては、芯材として金属材料又
はセラミックス材料が用いられる。金属材料としては、
例えばチタンやタンタルなどの金属、コバルト−クロム
系合金やステンレス鋼などの合金が挙げられる。セラミ
ックス材料としては、例えばＡｔ２０３、ＺｒＯ２、Ｔ
ｉＯ２、０ａＯ−Ａｔ２０３、Ａｚ２ｏ３−ｓｉｏ２系
ガラス、ＳｉＯ２−Ｎａ２０−Ｃ！ａｏ Ｐ２Ｏ５系カ
ラス（バイオガラス）、カーボンなどが挙ケられる。In the implant of the present invention, a metal material or a ceramic material is used as the core material. As a metal material,
Examples include metals such as titanium and tantalum, and alloys such as cobalt-chromium alloys and stainless steel. Examples of ceramic materials include At203, ZrO2, T
iO2, 0aO-At203, Az2o3-sio2 glass, SiO2-Na20-C! Examples include ao P2O5 glass (bioglass) and carbon.
本発明インプラントにおける多孔質層に用いる水酸アパ
タイトＣｃａｉＯ（ＰＯ４）６（ＯＨ）２’ ］として
は、種々の方法で得られる合成アバタイＩｆ用いてもよ
いし、を椎動物の骨、歯などから回収された生体アパタ
イトを用いてもよい。合成水ｊＪｌアパタイトは、例え
ばＣａＨＰＯ４と過剰のＣａＯと’１９００〜１３００
℃の高温下に水蒸気気流中で反応させる乾式合成法、あ
るいは生体温度３７℃、生理的ｐＨ７，１〜７．４の条
件下で、０．５モル／ｌのカルシウムとリン酸水溶液と
を反応させる湿式合成法によって製造することができる
。この水酸アパタイトは骨の無機質の主成分と同じ組成
であり、生体親和性に優れ、かつ自然骨と容易に化合結
合金つくる〇
一方、ガラスとしては、例えばＳｉＯ２−Ｎａ２０ 系
ガラスや５１０２−Ｎａ２０−に２０−ＭｇＯ系ガラス
に多量のＣａＯとＰ２Ｏ５を含有させたもの、いわゆる
ノくイオガラスなどが挙げられ、通常下記の組成ＳｉＯ
２ ２０，０〜６０．ＯＮ量チＰ２Ｏ５５，Ｏ〜４
０．０重量１も
Ｎａ２Ｏ２．７〜２０．０重ｉ％
に２０ ０．４〜２０．０重量％
Ｍｇ、０ ２．９〜３０．０重量係Ｃ重量％
５．０〜４０．０重量％ｔＷするものが好ましく用いら
れる。このガラスては、さらに０．００５〜３．ＯＭ量
係のフッ素を含有していてもよい。As the hydroxyapatite CcaiO(PO4)6(OH)2' used for the porous layer in the implant of the present invention, synthetic apatite If obtained by various methods may be used, or hydroxyapatite If obtained from vertebrate bones, teeth, etc. Recovered biological apatite may also be used. Synthetic water jJl apatite, for example, contains CaHPO4 and excess CaO and '1900-1300
A dry synthesis method in which the reaction is carried out in a steam stream at a high temperature of 0.5 mol/l of calcium and a phosphoric acid aqueous solution under the conditions of a biological temperature of 37°C and a physiological pH of 7.1 to 7.4. It can be manufactured by a wet synthesis method. This hydroxyapatite has the same composition as the main mineral component of bone, has excellent biocompatibility, and easily forms a compound bond with natural bone.On the other hand, as a glass, for example, SiO2-Na20 glass or 5102- Examples include Na20- and 20-MgO glass containing a large amount of CaO and P2O5, so-called nokuio glass, etc., which usually have the following composition SiO
2 20,0~60. ON amount Chi P2O55, O~4
0.0 weight 1 also Na2O2.7-20.0 weight i% to 20 0.4-20.0 weight% Mg, 0 2.9-30.0 weight ratio C weight%
Those having a tW of 5.0 to 40.0% by weight are preferably used. This glass is further 0.005 to 3. It may contain fluorine in an OM amount.
このようなガラスは生体に対して無害で、かつ生体親和
性に優れる上に、自然骨と化学結合をつくるなど、優れ
た性質を有している。Such glasses are harmless to living organisms, have excellent biocompatibility, and have excellent properties such as forming chemical bonds with natural bones.
本発明においては、このガラスの成分と前記水酸アパタ
イト粉末との混合ペーストｌ調製し、金属製又・はセラ
ミックス製インプラント芯材の表面に塗布したのち焼成
する。水酸アパタイト粉末と該ガラス成分との割合てつ
いては、通常水酸アパタイト粉末１００重量部に対し、
ガラス成分が５〜１００重量部の割合で用いられる。ま
た、水酸アパタイト粉末の粒重は１０〜１０００μｌ！
１の鞄囲にあることが好−土しく、さらに、該粉末自体
が多孔質であることが好ましい。焼成温度は通常１００
〜１３００℃の範囲で選ばれる。In the present invention, a mixed paste l of the glass components and the hydroxyapatite powder is prepared, applied to the surface of a metal or ceramic implant core material, and then fired. The ratio of the hydroxyapatite powder and the glass component is usually 100 parts by weight of the hydroxyapatite powder.
The glass component is used in an amount of 5 to 100 parts by weight. In addition, the particle weight of hydroxyapatite powder is 10 to 1000 μl!
It is preferable that the powder be present within the range of 1, and it is further preferable that the powder itself is porous. Firing temperature is usually 100
The temperature is selected within the range of ~1300°C.
このようにして、金属製又はセラミックス製インプラン
ト芯材の表面に水酸アパタイト全主体とする多孔質層が
形成される。この多孔質層の厚さは、少なくとも０．０
５１ｍ、好ましくは０．１〜ｌズ真の範囲である。In this way, a porous layer consisting entirely of hydroxyapatite is formed on the surface of the metal or ceramic implant core material. The thickness of this porous layer is at least 0.0
51 m, preferably in the range of 0.1 to 1 s true.
本発明においては、このようにして得られたインプラン
トの表面露出部全所望に応じ、塩素イオンやフッ素イオ
ンを含有する薬剤で処理して、その表面におけろ水酸ア
バメイトの水酸イオン全ノ・ロゲンイオンでイオン交換
することにより、該表面露出部を耐う触性の優れたもの
とすることができる。In the present invention, the entire exposed surface of the implant thus obtained is treated with a drug containing chloride ions or fluorine ions, as desired, to eliminate all hydroxyl ions of hydroxyl abamate on the surface. - By ion-exchanging with rogane ions, the exposed surface portion can be made to have excellent tactility.
次に１本発明の人工歯根用イ／プラントヲ添付図面に従
って説明すると、第１図は本発明の人工歯根用インプラ
ントの構造の１例を示す断面図であり、このものは台座
部分１とその底部に取り付けられた突起部２とを金属け
ｆ斗又はセラミックス材料で一体的に形成し、両者の全
表面にわたって、水酸アパタイトとガラスとから成る多
孔質層３全被覆ｊ〜で構成されている。Next, the artificial tooth root implant/plant of the present invention will be explained with reference to the attached drawings. Fig. 1 is a sectional view showing an example of the structure of the artificial tooth root implant of the present invention, and this one shows the pedestal portion 1 and its bottom. A porous layer 3 made of hydroxyapatite and glass is formed over the entire surface of both of the protrusions 2 attached to the protrusion 2 and is integrally formed of metal or ceramic material. .
このような構造のインプラント以外にも、第２図ＡＫ示
すような円柱状で底部のみが球状の構造を有するインプ
ラントも好適である。第２図Ａは本発明の人工歯根用イ
ンプラントの構造の他の例を示す斜視図であり、台座部
分１と突起部２とが金属材料又はセラミックス材料で一
体的に形成された芯材６の表面に、水酸アパタイトとガ
ラスとから成る多孔質層３が被覆された構造を有してい
る。第２図Ｂは多孔質層３の拡大図であり、４はカラス
層、５は水酸アパタイト粒子である。In addition to implants having such a structure, implants having a cylindrical structure with only a spherical bottom portion as shown in FIG. 2AK are also suitable. FIG. 2A is a perspective view showing another example of the structure of the artificial tooth root implant of the present invention, in which the pedestal portion 1 and the projection portion 2 are integrally formed of a metal material or a ceramic material. It has a structure in which the surface is coated with a porous layer 3 made of hydroxyapatite and glass. FIG. 2B is an enlarged view of the porous layer 3, where 4 is a glass layer and 5 is a hydroxyapatite particle.
発明の効果
本発明によると、特殊な溶射装置を用いることなく、金
属製又はセラミックス製インプラント芯材の表面に水酸
アパタイトヲ主体とする多孔質層を容易に形成すること
ができる。Effects of the Invention According to the present invention, a porous layer mainly composed of hydroxyapatite can be easily formed on the surface of a metal or ceramic implant core material without using a special thermal spraying device.
本発明の人工歯根用イノブラントは、芯材の全表面Ｇて
わたって、水酸アーパタイトとガラスとから成る多孔質
層で被覆されているので生体親和性に優れる上に、多孔
質層の気孔に骨細胞が進入し、強固な固定が得られ、し
かもこの気孔の大きさは水酸アパタイト粉末の粒径、ガ
ラスと水酸アパクィト粉末との混合割合を変えることに
より、任意に調節できるので、骨細胞が進入しやすい大
きさに孔径を容易に設定しつるという特徴を■［〜てい
る。The innoblunt for artificial tooth roots of the present invention is coated over the entire surface G of the core material with a porous layer consisting of hydroxyapatite and glass, so it has excellent biocompatibility and is also suitable for the pores of the porous layer. Osteocytes enter and firm fixation is obtained, and the size of these pores can be adjusted arbitrarily by changing the particle size of the hydroxyapatite powder and the mixing ratio of glass and hydroxyapatite powder. The pore size can be easily set to a size that allows cells to easily enter.
さらに、芯材として金属材料又はセラミック材料を用い
ているので、圧縮強度、曲げ強度、引張り強度、耐衝撃
強度などの機械的強度に優れている。Furthermore, since a metal material or a ceramic material is used as the core material, it has excellent mechanical strength such as compressive strength, bending strength, tensile strength, and impact strength.
実施例 次に実施例によυ本発明をさら知詳細に説明する。Example Next, the present invention will be explained in more detail with reference to Examples.
実施例
水酸アパタイト（乾式合成法による比重３．２、平均粒
径約１００μｍの白色粉末）１００重量部に対し、Ｎａ
２Ｏ２７，５重量％、ＣａＯ２４，５重−１重％、Ｓｉ
Ｏ２４５．０重量％及びＰ２Ｏ５５．０重量％から成る
バイオガラス成分１０重量部を配合し、有機溶剤に分散
させて混合ペーストを調製した。Example For 100 parts by weight of hydroxyapatite (white powder with a specific gravity of 3.2 and an average particle size of about 100 μm by dry synthesis method), Na
2O27.5wt%, CaO24.5wt-1wt%, Si
A mixed paste was prepared by blending 10 parts by weight of a bioglass component consisting of 45.0% by weight of O2 and 55.0% by weight of P2O and dispersing it in an organic solvent.
次に、第１図に示す形状のチタン製芯材の全表面に、前
記混合ペーストラ塗布したのち、約７００℃で１時間焼
成して、厚さ５００μｍの水酸アパタイトとバイオガラ
スとから成る多孔質層が該芯材の全表面疋わたって設け
られた人工歯根用インプラントを作成した。Next, after coating the entire surface of the titanium core material having the shape shown in FIG. An artificial tooth root implant was prepared in which the quality layer was provided over the entire surface of the core material.
また、酸化アルミニウム成形体１１７００℃で５時間焼
結して得たセラミックス製芯材を用い、前記と同様（て
して人工歯根用インプラントラ作成した。In addition, an implant for an artificial tooth root was prepared in the same manner as described above using a ceramic core material obtained by sintering an aluminum oxide molded body at 11,700° C. for 5 hours.
第１図及び第２図Ａはそれぞれ本発明の人工歯根用イン
プラントの構造の異なった例を示す断面図及び斜視図、
第２図Ｂは水酸アパタイトとガラスとから成る多孔質層
の拡大図であり、図中符号１は台座部分、２は実相部分
、３は水酸アパタイトとガラスとから成る多孔質層、４
はガラス層、５は水酸アパタイト粒子、６は芯材である
。
第１図
第２図FIG. 1 and FIG. 2A are a sectional view and a perspective view, respectively, showing different examples of the structure of the artificial tooth root implant of the present invention;
FIG. 2B is an enlarged view of a porous layer made of hydroxyapatite and glass, in which reference numeral 1 is a pedestal part, 2 is a real phase part, 3 is a porous layer made of hydroxyapatite and glass, and 4 is a porous layer made of hydroxyapatite and glass.
5 is a glass layer, 5 is a hydroxyapatite particle, and 6 is a core material. Figure 1 Figure 2
Claims (1)
トの芯材の表面に、水酸アパタイトとガラスとから成る
多孔質層を設けたことを特徴とする人工歯根用インプラ
ント。 ２ ガラスが、下記の組成 ＳｉＯ＿２ ２０．０〜６０．０重量％ Ｐ＿２Ｏ＿５ ５．０〜４０．０重量％ Ｎａ＿２Ｏ ２．７〜２０．０重量％ Ｋ＿２Ｏ ０．４〜２０．０重量％ ＭｇＯ ２．９〜３０．０重量％ ＣａＯ ５．０〜４０．０重量％ を有するものである特許請求の範囲第１項記載のインプ
ラント。 ３ 金属製インプラント又はセラミックス製インプラン
トの芯材の表面に、水酸アパタイト粉末とガラス成分と
の混合ペーストを塗布し、次いで焼成して該表面に水酸
アパタイトとガラスとから成る多孔質層を設けることを
特徴とする人工歯根用インプラントの製造方法。 ４ ガラスが、下記の組成 ＳｉＯ＿２ ２０．０〜６０．０重量％ Ｐ＿２Ｏ＿５ ５．０〜４０．０重量％ Ｎａ＿２Ｏ ２．７〜２０．０重量％ Ｋ＿２Ｏ ０．４〜２０．０重量％ ＭｇＯ ２．９〜３０．０重量％ ＣａＯ ５．０〜４０．０重量％ を有するものである特許請求の範囲第３項記載の方法。[Claims] 1. An artificial tooth root implant, characterized in that a porous layer made of hydroxyapatite and glass is provided on the surface of a core material of a metal implant or a ceramic implant. 2 The glass has the following composition: SiO_2 20.0-60.0% by weight P_2O_5 5.0-40.0% by weight Na_2O 2.7-20.0% by weight K_2O 0.4-20.0% by weight MgO 2. The implant according to claim 1, having a content of 9 to 30.0% by weight and 5.0 to 40.0% by weight of CaO. 3. Applying a mixed paste of hydroxyapatite powder and a glass component to the surface of the core material of a metal implant or ceramic implant, and then firing it to provide a porous layer consisting of hydroxyapatite and glass on the surface. A method for manufacturing an artificial tooth root implant, characterized by: 4 The glass has the following composition: SiO_2 20.0-60.0% by weight P_2O_5 5.0-40.0% by weight Na_2O 2.7-20.0% by weight K_2O 0.4-20.0% by weight MgO 2. The method according to claim 3, wherein the content is 9 to 30.0% by weight and CaO 5.0 to 40.0% by weight.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61172867A JPS6331654A (en) | 1986-07-24 | 1986-07-24 | Implant for artificial dental root and its production |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61172867A JPS6331654A (en) | 1986-07-24 | 1986-07-24 | Implant for artificial dental root and its production |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS6331654A true JPS6331654A (en) | 1988-02-10 |
Family
ID=15949770
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP61172867A Pending JPS6331654A (en) | 1986-07-24 | 1986-07-24 | Implant for artificial dental root and its production |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6331654A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5077132A (en) * | 1986-10-20 | 1991-12-31 | Shigeo Maruno | Biocompatible composite material and a method for producing the same |
| US5456601A (en) * | 1994-01-11 | 1995-10-10 | Sendax; Victor I. | Sinus dental implant stabilizer |
-
1986
- 1986-07-24 JP JP61172867A patent/JPS6331654A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5077132A (en) * | 1986-10-20 | 1991-12-31 | Shigeo Maruno | Biocompatible composite material and a method for producing the same |
| US5456601A (en) * | 1994-01-11 | 1995-10-10 | Sendax; Victor I. | Sinus dental implant stabilizer |
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