JPS63145236A - Remedy for trichophytosis - Google Patents
Remedy for trichophytosisInfo
- Publication number
- JPS63145236A JPS63145236A JP61290361A JP29036186A JPS63145236A JP S63145236 A JPS63145236 A JP S63145236A JP 61290361 A JP61290361 A JP 61290361A JP 29036186 A JP29036186 A JP 29036186A JP S63145236 A JPS63145236 A JP S63145236A
- Authority
- JP
- Japan
- Prior art keywords
- remedy
- trichophytosis
- water
- horsetail
- extract
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 208000002474 Tinea Diseases 0.000 title claims abstract description 12
- 206010067409 Trichophytosis Diseases 0.000 title abstract 4
- 241000218645 Cedrus Species 0.000 claims description 11
- 241000893966 Trichophyton verrucosum Species 0.000 claims description 7
- 239000004480 active ingredient Substances 0.000 claims description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 8
- 241000195955 Equisetum hyemale Species 0.000 abstract description 4
- BWMISRWJRUSYEX-SZKNIZGXSA-N terbinafine hydrochloride Chemical compound Cl.C1=CC=C2C(CN(C\C=C\C#CC(C)(C)C)C)=CC=CC2=C1 BWMISRWJRUSYEX-SZKNIZGXSA-N 0.000 abstract description 4
- 201000004647 tinea pedis Diseases 0.000 abstract description 4
- 230000000694 effects Effects 0.000 abstract description 3
- RMAQACBXLXPBSY-UHFFFAOYSA-N silicic acid Chemical compound O[Si](O)(O)O RMAQACBXLXPBSY-UHFFFAOYSA-N 0.000 abstract description 3
- 235000012239 silicon dioxide Nutrition 0.000 abstract description 3
- 241000196324 Embryophyta Species 0.000 abstract description 2
- 238000002036 drum drying Methods 0.000 abstract description 2
- 239000007787 solid Substances 0.000 abstract description 2
- 239000002904 solvent Substances 0.000 abstract description 2
- 238000001694 spray drying Methods 0.000 abstract description 2
- 239000007788 liquid Substances 0.000 abstract 2
- 244000085625 Equisetum Species 0.000 abstract 1
- 238000007865 diluting Methods 0.000 abstract 1
- 239000002994 raw material Substances 0.000 abstract 1
- 230000000638 stimulation Effects 0.000 abstract 1
- 206010037844 rash Diseases 0.000 description 6
- 239000003814 drug Substances 0.000 description 5
- 235000021384 green leafy vegetables Nutrition 0.000 description 5
- 229940124597 therapeutic agent Drugs 0.000 description 5
- 210000003371 toe Anatomy 0.000 description 5
- 241000219198 Brassica Species 0.000 description 4
- 235000003351 Brassica cretica Nutrition 0.000 description 4
- 235000003343 Brassica rupestris Nutrition 0.000 description 4
- QKSKPIVNLNLAAV-UHFFFAOYSA-N bis(2-chloroethyl) sulfide Chemical compound ClCCSCCCl QKSKPIVNLNLAAV-UHFFFAOYSA-N 0.000 description 4
- 230000003902 lesion Effects 0.000 description 4
- 235000010460 mustard Nutrition 0.000 description 4
- 208000010201 Exanthema Diseases 0.000 description 3
- 241000233866 Fungi Species 0.000 description 3
- 201000005884 exanthem Diseases 0.000 description 3
- 210000003491 skin Anatomy 0.000 description 2
- 208000017520 skin disease Diseases 0.000 description 2
- 241000242722 Cestoda Species 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 241000519995 Stachys sylvatica Species 0.000 description 1
- 241000130764 Tinea Species 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000001882 diuretic effect Effects 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 210000000981 epithelium Anatomy 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 210000002683 foot Anatomy 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000007803 itching Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
Description
【発明の詳細な説明】
〔発明の利用分野〕
本発明は白層菌によって起こる皮膚病である水虫や田虫
等の病型に特に有効な白癬治療剤に関するものである。DETAILED DESCRIPTION OF THE INVENTION [Field of Application of the Invention] The present invention relates to a therapeutic agent for ringworm that is particularly effective against types of skin diseases caused by fungi, such as athlete's foot and tapeworm.
水虫や田虫等の皮膚病である白層は、一種の糸状菌、す
なわち白府菌の感染によって起こるとされているが、そ
の症状は様々で足指の間から始まり、小さな水泡ができ
てかゆみが強（、悪化すると白癬疹ができたり、足指の
間の皮膚が白変し、それがむけて赤くただれたりする。White layer, a skin disease caused by athlete's foot and fieldworm, is said to be caused by infection with a type of filamentous fungus, the fungus Shirofu.The symptoms vary, starting between the toes, causing small blisters and itching. If the condition worsens, a ringworm rash may develop, and the skin between the toes turns white, peeling and becoming red and sore.
稀には足の裏や手の指、手のひらにも病変が及び、爪が
冒されると灰白色に濁り、表面が凹凸状となって厚くな
ったりすることもある。In rare cases, the lesions may also extend to the soles of the feet, fingers, and palms, and when the nails are affected, they may become grayish-white and cloudy, and the surface may become uneven and thick.
このような自溶に基づく病変を治療すべく、これまでに
様々な治療剤が提供されてきたが、これら従来の治療剤
では一時的に病変を抑えることができても、永続的に根
治させることはきわめて困難で、相当期間の経過により
再発を繰り返しているというのが現状である。Various therapeutic agents have been provided to treat such self-dissolving lesions, but although these conventional therapeutic agents can temporarily suppress the lesions, they do not permanently cure them. It is extremely difficult to do so, and the current situation is that recurrences occur repeatedly over a considerable period of time.
本発明者は、このように仲々根治し難い白癬に対し有効
に作用する治療剤を得るべく種々の実験、研究を重ねた
結果、これまで利尿作用があることで知られているトク
サ科の多年生シダ植物である杉菜の抽出液が白層の根本
的治療に卓効のあることを見い出し本発明を完成するに
敗ったものである。As a result of repeated experiments and research in order to obtain a therapeutic agent that is effective against ringworm, which is difficult to completely cure, the present inventor discovered a perennial of the horsetail family, which has been known to have diuretic properties. It was discovered that the extract of the fern plant Sugina is extremely effective in the fundamental treatment of the white layer, and was unsuccessful in completing the present invention.
本発明を詳述すれば、杉菜の抽出液を有効成分としたこ
とを特徴とする白層治療剤であり、杉菜の抽出液は、採
取してきた杉菜を水で煮出すことにより容易に得ること
ができ、この水に溶解している杉菜の抽出液中に患部を
そのまま浸漬させることにより白層を治療するものであ
るが、抽出液はこれを濃縮して、治療時に水等の溶媒で
希釈して用いるようにしてもよいし、あるいはこの抽出
液を必要に応じて真空濃縮後、噴霧乾燥、真空ドラム乾
燥等公知の方法で乾燥し、粉砕して固形状乃至粉末状と
し、これを水等に熔解して治療剤として用いることもで
きるものである。More specifically, the present invention is a white layer treatment agent characterized by using an extract of Cedar mustard as an active ingredient. The white layer is treated by immersing the affected area directly in the cedar mustard extract dissolved in water, but the extract is concentrated and diluted with a solvent such as water during treatment. Alternatively, if necessary, this extract may be concentrated in vacuum, dried by a known method such as spray drying or vacuum drum drying, pulverized into a solid or powdered form, and mixed with water. It can also be used as a therapeutic agent by dissolving it.
杉菜は生えている場所によりある程度の違いがあるが、
重量比で約５％〜１６％の珪酸が含まれており、この珪
酸が患部の治療に効果があるものと推定される。There are some differences in cedar greens depending on where they grow,
It contains approximately 5% to 16% silicic acid by weight, and it is estimated that this silicic acid is effective in treating the affected area.
■ 野原に自生している杉菜を採取し、容器内に杉菜５
００ｇに対し、水１１を加え、加熱沸騰させ３０分程度
煮出した後、火を止め室温にて自然冷却し、杉菜の抽出
液を得た。■ Collect cedar greens growing wild in the field and put 5 cedar greens in a container.
After adding 11 parts of water to 00 g and boiling for about 30 minutes, the heat was turned off and the mixture was naturally cooled to room temperature to obtain a cedar mustard extract.
この抽出液中に、足指に白癬疹を有する患者Ａの患部を
一日３０程度度浸漬し、これを７日間継続して行ったと
ころ、７日月に白癬疹が消失し、皮膚の再生回復が始ま
っていることが確認された。The affected area of patient A, who has ringworm eruptions on his toes, was soaked in this extract about 30 times a day, and this was continued for 7 days.The ringworm eruptions disappeared on the 7th day, and the skin regenerated. It was confirmed that recovery had begun.
すなわち、患者Ａの患部を顕微鏡で観察すると、白徊疹
のあったところに新しい上皮（表皮）の再生が始まって
いた。That is, when patient A's affected area was observed under a microscope, it was found that new epithelium (epidermis) had begun to regenerate where the white rash had been.
■ 実施例■と同一の場所で採取してきた杉菜１ ｋｇ
に対し、水１１を加え、実施例■と同様の操作で得た杉
菜の抽出液中に、患者Ａよりも症例の重い患者Ｂの足指
を一日２回、それぞれ３０分間程度浸漬し、これを１５
日間継続して行ったところ、病変が回復に向かい、新し
い上皮の再生が始まっていることが確認された。■ 1 kg of cedar greens collected from the same location as Example ■
To this, water 11 was added, and the toes of patient B, who had a more severe case than patient A, were immersed for about 30 minutes twice a day in the extract of cedar rape obtained in the same manner as in Example ①. This is 15
When the treatment was continued for several days, it was confirmed that the lesions were beginning to recover and that new epithelial regeneration had begun.
■ 実施例■で得た抽出液を濃縮し、これを足指に白癬
疹を有する患者Ｃの患部に一日一回５ｃｃ程度を均一に
塗布し、５日間継続したところ、最終日には白府疹が消
失していることが確認された。■ The extract obtained in Example ■ was concentrated, and about 5 cc of this was evenly applied once a day to the affected area of patient C, who had tinea eruption on her toes. When this was continued for 5 days, on the last day, whiteness appeared. It was confirmed that the rash had disappeared.
本発明の構成、作用は以上のとおりであり、杉菜に含ま
れている薬理成分が白癬凹の根治に有効に作用し、一般
市販品のごとく過度な刺激等で皮膚を逆に痛める等の不
都合もなく、自然治癒に近い状態で患部を再生すること
ができる。The structure and action of the present invention are as described above, and the pharmacological components contained in Cedar mustard effectively act to completely cure ringworm cavities. The affected area can be regenerated in a state close to natural healing.
また、杉菜は山林や野原で容易に入手することができ、
自然に自生しているものであるから化学合成品にみられ
るような副作用等の危険性も全くなく、安全且つ安価に
水虫や田虫のような白層を根治することができるもので
ある。In addition, cedar greens can be easily obtained in forests and fields.
Since it is a naturally occurring product, there is no danger of side effects such as those seen with chemically synthesized products, and it can be used to safely and inexpensively cure white spots such as athlete's foot and field worms.
Claims (1)
療剤。A treatment for ringworm characterized by containing an extract of cedar rape as an active ingredient.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61290361A JPS63145236A (en) | 1986-12-08 | 1986-12-08 | Remedy for trichophytosis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61290361A JPS63145236A (en) | 1986-12-08 | 1986-12-08 | Remedy for trichophytosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS63145236A true JPS63145236A (en) | 1988-06-17 |
Family
ID=17755038
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP61290361A Pending JPS63145236A (en) | 1986-12-08 | 1986-12-08 | Remedy for trichophytosis |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS63145236A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0342706A2 (en) * | 1988-05-20 | 1989-11-23 | Dow Corning Corporation | Method of treating tinea pedis and related dermathophytic infections |
| JP2003061617A (en) * | 2001-08-30 | 2003-03-04 | Univ Nihon | Health food having antiallergic action |
| KR100467022B1 (en) * | 1997-02-19 | 2005-06-22 | 주식회사 엘지생활건강 | Cosmetic soap composition |
-
1986
- 1986-12-08 JP JP61290361A patent/JPS63145236A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0342706A2 (en) * | 1988-05-20 | 1989-11-23 | Dow Corning Corporation | Method of treating tinea pedis and related dermathophytic infections |
| KR100467022B1 (en) * | 1997-02-19 | 2005-06-22 | 주식회사 엘지생활건강 | Cosmetic soap composition |
| JP2003061617A (en) * | 2001-08-30 | 2003-03-04 | Univ Nihon | Health food having antiallergic action |
| JP4534003B2 (en) * | 2001-08-30 | 2010-09-01 | 学校法人日本大学 | Health food with antiallergic action |
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