JPS62106756A - Nuclear magnetic resonance apparatus - Google Patents
Nuclear magnetic resonance apparatusInfo
- Publication number
- JPS62106756A JPS62106756A JP60248621A JP24862185A JPS62106756A JP S62106756 A JPS62106756 A JP S62106756A JP 60248621 A JP60248621 A JP 60248621A JP 24862185 A JP24862185 A JP 24862185A JP S62106756 A JPS62106756 A JP S62106756A
- Authority
- JP
- Japan
- Prior art keywords
- magnetic field
- magnet
- transmitter
- nuclear magnetic
- resonance apparatus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Magnetic Resonance Imaging Apparatus (AREA)
Abstract
(57)【要約】本公報は電子出願前の出願データであるた
め要約のデータは記録されません。(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.
Description
【発明の詳細な説明】
[産業上の利用分野〕
本発明は核磁気共鳴装置(NMR装置)に関し、簡単な
構成で生体等の表面付近のNMR測定を行うことのでき
るNMR装置に関する。DETAILED DESCRIPTION OF THE INVENTION [Field of Industrial Application] The present invention relates to a nuclear magnetic resonance apparatus (NMR apparatus), and more particularly, to an NMR apparatus that can perform NMR measurements near the surface of a living body or the like with a simple configuration.
[従来技術]
現在開発が進められているN M R診断装置では、常
伝導型又は超伝導型磁石内に形成される強磁場内に全身
又は体の一部を入れ、体の表面に送受信コイルを取付け
、そのコイルのあたっている部分について水素又は他の
元素の分布又は化学シフトを測定する。[Prior art] In the NMR diagnostic device currently under development, the whole body or a part of the body is placed in a strong magnetic field formed within a normal or superconducting magnet, and a transmitter/receiver coil is placed on the surface of the body. Attach the coil and measure the distribution or chemical shift of hydrogen or other elements in the area covered by the coil.
[発明が解決しようとする問題点1
そのため、磁石は非常に大型となり、価格の上昇は避け
られないし、全身又は体の一部が狭い空間にとじこめら
れるため、患者にとって心理的な負担が加わり、測定で
きる部位も制限を受けることも避けられない。[Problem to be Solved by the Invention 1] As a result, the magnet becomes very large, which inevitably increases the price, and the whole body or part of the body is confined in a small space, which adds psychological burden to the patient. It is inevitable that there will be restrictions on the areas that can be measured.
本発明は、測定対象を磁石の中に入れるのではなく、測
定対象を磁石の端部に押し当てて測定するという新しい
考え方に基づき、大型の磁石を必要とぜず簡単な構成で
生体等の表面付近のNMR測定を行うことのできるNM
R装置を提供することを目的としている。The present invention is based on a new concept of measuring the object by pressing it against the end of the magnet, rather than placing the object in the magnet. NM that allows near-surface NMR measurements
The purpose is to provide an R device.
[問題点を解決するための手段]
この目的を達成するため、本発明にかかるNMR装置は
、測定対蒙に近接し得る端部を持ち、該端部が面した測
定対象の特定部分に一方向のvii場を印加するための
磁石と、該特定部分に印加される磁場に略直交する方向
の高周波E4j場を前記特定部分に印加するために前記
端部を挟/υで対象に配置される1対の送受信コイルと
、該送受信コイルへ観測用パルスを供給するための送信
回路と、該送受信コイルに誘起された共鳴信号が供給さ
れる受信回路を備えたことを特徴としでいる。[Means for Solving the Problems] In order to achieve this object, the NMR apparatus according to the present invention has an end that can be brought close to the measurement target, and a specific part of the measurement target that the end faces. a magnet for applying a vii field in the direction vii, and a magnet arranged symmetrically with /υ between the ends in order to apply a high frequency E4j field in a direction substantially perpendicular to the magnetic field applied to the specific part to the specific part. The device is characterized by comprising a pair of transmitter/receiver coils, a transmitter circuit for supplying observation pulses to the transmitter/receiver coils, and a receiver circuit to which resonance signals induced in the transmitter/receiver coils are supplied.
[作用1
測定対象を磁石の端部に近接さシ古れば、測定対象の特
定部位には一方向の磁場が印加される。そして、前記端
部を挟んで対象に配置される送受信コイルに送信回路か
ら観測パルスを供給すれば、前記特定部位には磁石から
一方向のta場と、送受信コイルから該磁場に略直交す
る方向を持つ高周波磁場が印加されることになり、この
特定部位についてNMR測定を行うことができる。[Effect 1] When the object to be measured is brought close to the end of the magnet, a unidirectional magnetic field is applied to a specific part of the object to be measured. Then, if an observation pulse is supplied from the transmitting circuit to the transmitting/receiving coil placed on the target with the end in between, the specific region receives a ta field from the magnet in one direction, and a ta field from the transmitting/receiving coil in a direction substantially orthogonal to the magnetic field. A high frequency magnetic field having a certain area is applied, and NMR measurements can be performed on this specific area.
以下、図面を用いて本発明の一実施例を詳説する。Hereinafter, one embodiment of the present invention will be explained in detail using the drawings.
「実施例」
添付図面は本発明の一実施例の構成を示ず概略図である
。図にJシいて1は測定対象、2はこの測定対象に対し
て近接し得る極3を持つ永久磁石、4は上記極3を挟ん
で逆ハの字の形に配置される一対の送受信コイル、5は
上記磁石2及び送受信コイル4を支持するためのケース
、6は上記送受信コイルに観測用高周波パルスを供給す
るための送信回路、7は送受信コイルに誘起された共鳴
信号が供給される受信回路、8は受信回路7を介しで出
された共鳴信号を処理するためのコンビコータである。``Embodiment'' The attached drawings are schematic diagrams that do not show the structure of an embodiment of the present invention. In the figure, 1 is the object to be measured, 2 is a permanent magnet with a pole 3 that can be close to the object to be measured, and 4 is a pair of transmitter/receiver coils arranged in an inverted V shape with the pole 3 in between. , 5 is a case for supporting the magnet 2 and the transmitting/receiving coil 4, 6 is a transmitting circuit for supplying high frequency pulses for observation to the transmitting/receiving coil, and 7 is a receiving unit to which the resonance signal induced in the transmitting/receiving coil is supplied. The circuit 8 is a combicoater for processing the resonance signal outputted via the receiving circuit 7.
上記構成において、磁石2の極3からは破線で示すよう
な静磁場1−1oが発生し、この静磁場)−1゜は極3
に近接する測定対象の特定部分に印加される。そして、
送信回路6から観測用の高周波パルス(パルス列)を送
受信コイル4へ送れば、送受信コイル4からは、図にお
いて一点鎖線で示すような高周波パルス磁場が発生する
。In the above configuration, a static magnetic field 1-1o as shown by the broken line is generated from the pole 3 of the magnet 2, and this static magnetic field )-1° is the pole 3 of the magnet 2.
is applied to a specific part of the object to be measured in the vicinity of . and,
When a high-frequency pulse (pulse train) for observation is sent from the transmitter circuit 6 to the transmitter-receiver coil 4, a high-frequency pulse magnetic field as shown by the dashed line in the figure is generated from the transmitter-receiver coil 4.
この高周波パルス磁場と前記静磁場Hoが略直交して存
在する斜線を施した領域Aで共鳴条件が成立覆るため、
この領vJ、Aに存在する観測核が励起され、高周波パ
ルス磁場照射後、送受信コイル4に誘起される共鳴信号
を受信回路7を介して取出し、コンピュータ8でフーリ
エ変換処理すれば、上記領域AについてのN M Rス
ペクトルを得ることができる。そして、このスペクトル
に基づき、上記領域Aに存在する元素のMあるいは化学
シフト等の情報を得ることができる。磁石を当てる位四
を変えれば、測定領域を任意に選択できることは言うま
でもない。Since the resonance condition is established in the shaded region A where this high-frequency pulsed magnetic field and the static magnetic field Ho are approximately perpendicular to each other,
The observation nucleus existing in this region vJ,A is excited, and after irradiation with a high-frequency pulsed magnetic field, the resonance signal induced in the transmitting/receiving coil 4 is extracted via the receiving circuit 7 and subjected to Fourier transformation processing by the computer 8. An NMR spectrum can be obtained for . Based on this spectrum, information such as M or chemical shift of the elements present in the region A can be obtained. It goes without saying that the measurement area can be arbitrarily selected by changing the position of the magnet.
尚、上記実施例では磁石に永久磁石を用いたが、常伝導
型あるいは超伝導型の磁石を用いても良いことは言うま
でもない。Although permanent magnets were used as magnets in the above embodiments, it goes without saying that normal conducting or superconducting magnets may also be used.
[効果]
以上詳述した如く、本発明によれば、磁石の中に測定対
象を入れるのではなく、磁石の端部に測定対象を当接さ
せるようにし、この端部を挟んで略対称に配置される一
対の送受信コイルを用いてN〜j R1lll定を行う
ようにしたため、構成が筒中となり、測定部位の制限が
少なく、測定対象にも心理的な圧迫がかかることのない
NMR装置が実現される。[Effects] As described in detail above, according to the present invention, the object to be measured is not placed inside a magnet, but is brought into contact with the end of the magnet, and the object is placed approximately symmetrically across this end. Since the N-j R1lll determination is performed using a pair of placed transmitting and receiving coils, the configuration is in the cylinder, there are fewer restrictions on the measurement site, and an NMR device that does not put psychological pressure on the measurement target has been realized. be done.
添付図面は本発明の一実施例の構成を示す概略図である
。The accompanying drawings are schematic diagrams showing the configuration of an embodiment of the present invention.
Claims (1)
対象の特定部分に一方向の磁場を印加するための磁石と
、該特定部分に印加される磁場に略直交する方向の高周
波磁場を前記特定部分に印加するために前記端部を挟ん
で対象に配置される1対の送受信コイルと、該送受信コ
イルへ観測用パルスを供給するための送信回路と、該送
受信コイルに誘起された共鳴信号が供給される受信回路
を備えたことを特徴とする核磁気共鳴装置。A magnet that has an end that can be close to the measurement target and applies a magnetic field in one direction to a specific part of the measurement target that the end faces, and a high frequency wave in a direction substantially orthogonal to the magnetic field applied to the specific part. a pair of transmitter/receiver coils placed across the ends to apply a magnetic field to the specific portion; a transmitter circuit for supplying observation pulses to the transmitter/receiver coils; 1. A nuclear magnetic resonance apparatus comprising a receiving circuit to which a resonance signal is supplied.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP60248621A JPS62106756A (en) | 1985-11-06 | 1985-11-06 | Nuclear magnetic resonance apparatus |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP60248621A JPS62106756A (en) | 1985-11-06 | 1985-11-06 | Nuclear magnetic resonance apparatus |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS62106756A true JPS62106756A (en) | 1987-05-18 |
Family
ID=17180835
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP60248621A Pending JPS62106756A (en) | 1985-11-06 | 1985-11-06 | Nuclear magnetic resonance apparatus |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS62106756A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6091241A (en) * | 1996-10-01 | 2000-07-18 | L'oreal | Device for examining a volume of small depth by nuclear magnetic resonance |
WO2005082244A1 (en) * | 2004-02-27 | 2005-09-09 | Hamano Life Science Research Foundation | Method for evaluating activity of hair root using magnetic resonance apparatus |
WO2016157182A1 (en) * | 2015-03-30 | 2016-10-06 | Shmri Haim Ltd. | System and hand-held probe for non-invasive real time magnetic resonance analysis of body tissue |
-
1985
- 1985-11-06 JP JP60248621A patent/JPS62106756A/en active Pending
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6091241A (en) * | 1996-10-01 | 2000-07-18 | L'oreal | Device for examining a volume of small depth by nuclear magnetic resonance |
WO2005082244A1 (en) * | 2004-02-27 | 2005-09-09 | Hamano Life Science Research Foundation | Method for evaluating activity of hair root using magnetic resonance apparatus |
WO2016157182A1 (en) * | 2015-03-30 | 2016-10-06 | Shmri Haim Ltd. | System and hand-held probe for non-invasive real time magnetic resonance analysis of body tissue |
CN107660270A (en) * | 2015-03-30 | 2018-02-02 | 舒姆里哈伊姆有限公司 | For carrying out the system and hand hold transducer of noninvasive real-time magnetic resonance analysis to bodily tissue |
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