JPS6131045A - Method of administering drug to cultivated fish - Google Patents
Method of administering drug to cultivated fishInfo
- Publication number
- JPS6131045A JPS6131045A JP59152112A JP15211284A JPS6131045A JP S6131045 A JPS6131045 A JP S6131045A JP 59152112 A JP59152112 A JP 59152112A JP 15211284 A JP15211284 A JP 15211284A JP S6131045 A JPS6131045 A JP S6131045A
- Authority
- JP
- Japan
- Prior art keywords
- drug
- film
- fish
- administration
- administering
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/80—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in fisheries management
- Y02A40/81—Aquaculture, e.g. of fish
Landscapes
- Fodder In General (AREA)
- Artificial Fish Reefs (AREA)
- Feed For Specific Animals (AREA)
- Farming Of Fish And Shellfish (AREA)
Abstract
Description
【発明の詳細な説明】
（産業上の利用分野）
本発明は養殖魚、例えばタイ、ブリ、ヒラメ、フグ等へ
の薬剤の投与方法に係る。DETAILED DESCRIPTION OF THE INVENTION (Industrial Field of Application) The present invention relates to a method for administering a drug to cultured fish, such as sea bream, yellowtail, flounder, and puffer fish.
（゛従来の技術）
魚類の養殖は近年盛んになって来ているが、養殖魚類の
内で例えばブリ（一般に賞味期から「）・マチ」と称さ
れている）のように生の餌しか食べない魚の養殖に際し
ては他の魚類の養殖には存しない種々の問題点があシ、
その１つが薬剤の投与である。(゛Prior art) Fish farming has become popular in recent years, but among farmed fish, for example, yellowtail (generally called ``machi'' due to its expiration date), only raw food is available. When farming non-edible fish, there are various problems that do not exist when farming other fish.
One of these is drug administration.
即ち、例えばブリの養殖に際して成る程度成長すればそ
の餌として鰯の総身を投与する必要性がある。この場合
に鰯は本来ブリの生育に必要な栄養素、無機質、ビタミ
ン類等を含有しているが、鰯を誤用として保存している
間にビタミン類殊にビタミンＢ群、ビタミンＣ，ビタミ
ンＥ等は牛酪の組織内に存在する酵素の作用や外的要因
により次第に分解されてしまい、養殖に充分な程残存し
ない状態に至ることが従来から知られている。That is, for example, when cultivating yellowtail, once the fish has grown to a certain level, it is necessary to feed the whole body of the sardine as feed. In this case, sardines originally contain nutrients, minerals, vitamins, etc. that are necessary for the growth of yellowtail, but while sardines are being stored incorrectly, vitamins, especially vitamin B group, vitamin C, vitamin E, etc. It has been known for a long time that cow and dairy products are gradually degraded by the action of enzymes present in the tissues of cows and dairy products and external factors, leading to a state in which they are no longer sufficient for aquaculture.
従って、ビタミン類の不足分を補なうために、現在養殖
業者は別途調製したビタミン製剤粒子を散布投与したり
、或いは又粘着液にビタミン類を溶解又は分散させ、こ
の粘着液に牛酪を浸漬して投与する等の方策を採ってい
る。Therefore, in order to make up for the lack of vitamins, farmers are currently spraying separately prepared vitamin preparation particles, or dissolving or dispersing vitamins in a sticky liquid, and immersing cows and dairy products in this sticky liquid. Measures are being taken to administer the drug.
ビタミン類以外の薬剤例えば病気の予防や治療の目的で
供される抗生物質や生育促進等の目的で供されるホルモ
ン類の投与に際してもビタミン類に関する上記投与と同
様の方策が採用されている。When administering drugs other than vitamins, such as antibiotics used to prevent or treat diseases, and hormones used to promote growth, the same strategies as above for vitamins are used.
（発明が解決しようとする問題点）
従来技術による上記のような薬剤投与方法には重大な欠
陥が存する。即ち、薬物を粒状に製剤化して散布投与す
る場合には養殖魚がこれに対して余シ興味・を示さない
ために摂取率が極めて低く、又薬物を粘着液に溶解又は
分散させこれを牛酪等の餌に付着させて投与する場合に
は水中への餌の投入と同時に薬物の大部分が流失してし
まい、従って何れにしても施用効率が極めて低いからで
ある。このことは薬剤を極めて過剰量使用せねばならな
いことを意味し、その結果養殖コストの上昇を招くのみ
ならず、これら薬剤の過剰投与は養殖場附近の水域に薬
剤濃度の極めて高い帯域が生じる可能性のあることを意
味しておシ、薬害発生の虞れすらある。(Problems to be Solved by the Invention) The above-mentioned drug administration methods according to the prior art have serious deficiencies. That is, when a drug is formulated into granules and administered by spraying, the uptake rate is extremely low because farmed fish do not show any interest in it. This is because when administering the drug by adhering it to bait, most of the drug will be washed away as soon as the bait is put into the water, and therefore the application efficiency will be extremely low in any case. Not only does this mean that chemicals have to be used in extremely excessive amounts, resulting in increased aquaculture costs, but overdosing of these chemicals can also create bands of extremely high drug concentrations in the waters near the farm. This means that it has a chemical nature, and there is even a risk of drug damage.
従って、本発明が解決しようとする問題点は、投与時に
おける水中への分散流失をほぼ完全に防止することがで
き且つ養殖魚の嗜好性を損わず、従って施与効率の高い
薬剤の投与方法を提供することにある。Therefore, the problem to be solved by the present invention is a method for administering a drug that can almost completely prevent dispersion and loss into water during administration, does not impair the palatability of cultured fish, and has high application efficiency. Our goal is to provide the following.
（問題点を解決するための手段及び作用）本発明によれ
ば、上記の問題点は、基本的には、餌としての生魚又は
生魚肉の表面に非水溶性であり可食性の被覆を施こし、
この被■により薬剤を保護して投与することにより解決
される。即ち、本発明によれば、非水溶性の可食性被覆
で薬剤が保護されているために水中に投入されても薬剤
の流出が阻止され且つ薬剤が餌と一体となされているた
めに養魚の嗜好性が損われないのである。(Means and effects for solving the problems) According to the present invention, the above problems can basically be solved by applying a water-insoluble and edible coating to the surface of raw fish or raw fish meat as feed. Strain,
This problem can be solved by administering the drug while protecting it. That is, according to the present invention, since the drug is protected by a water-insoluble edible coating, the drug is prevented from flowing out even if it is put into water, and the drug is integrated with the feed, making it easy to cultivate fish. The palatability is not impaired.
本発明方法により投与される薬剤としては各種ビタミン
類、抗生物質類、ホルモン類、栄養補強剤類（コリン、
坦汁、甘草等）等の一般に養殖魚用に供せられている薬
剤である。The drugs administered by the method of the present invention include various vitamins, antibiotics, hormones, and nutritional supplements (choline,
It is a drug commonly used for cultured fish, such as danjiru, licorice, etc.).
保護被覆としての皮膜はポリカチオンとポリアニオンと
の反応により形成することができ、この場合にポリカチ
オンとしてはキトサン、ポリリジン及びレシチンの少く
とも１種を、又ポリアニオンとしてはカラギーナン、ア
ルギン酸、アルギン酸塩、ペクチン、ガム類の少なくと
も１種を用いることができる。A film as a protective coating can be formed by a reaction between a polycation and a polyanion, and in this case, the polycation is at least one of chitosan, polylysine, and lecithin, and the polyanion is carrageenan, alginic acid, alginate, At least one of pectin and gums can be used.
生餌、例えば牛酪の表面に所定の薬剤な直接的に塗し、
その上に上記の保護被覆を形成することができるが、こ
の場合には薬剤の種類に依存し、例えばビタミンＢ群、
ビタミンＣ１ビタミンＥｌは鰯の組織中の酵素や空気中
に存在する酵素の作用により、次第にその活性が低下し
てしまうので、このような餌は長期保存には適当ではな
い。Apply a prescribed chemical directly to the surface of live feed, such as cow and dairy,
The above-mentioned protective coating can be formed thereon, depending on the type of drug, for example vitamins of the B group,
Since the activity of vitamin C and vitamin El gradually decreases due to the action of enzymes in the sardine tissues and enzymes present in the air, such feed is not suitable for long-term storage.
薬剤の失活を防止し、長期間例えば１年又はそれ以上に
亘る餌の保存後にも薬剤が充分な活性を保持しているよ
うになすためには、餌としての鰯組織や空気から薬剤ｔ
Ｓ断する必要性がある。このためには油脂類、蛋白質又
は燐脂質により薬剤を封入するのが有利である。このた
めに用いられる油脂類としては菜種油硬化油等を、蛋白
質としては凝固性のもの例えばゼイン（トウモロコシ起
原）、セリシン（絹糸起原）等を、又燐脂質としてはレ
シチン等を挙げることができ、これらは単独で或いは配
合して用いることができる。In order to prevent the deactivation of the drug and to ensure that the drug retains sufficient activity even after the feed has been stored for a long period of time, for example, one year or more, it is necessary to remove the drug from the sardine tissue used as feed or from the air.
There is a need to cut S. For this purpose, it is advantageous to encapsulate the drug with oils, proteins or phospholipids. Examples of fats and oils used for this purpose include hydrogenated rapeseed oil, proteins with coagulability such as zein (derived from corn) and sericin (derived from silk thread), and phospholipids such as lecithin. These can be used alone or in combination.
尚、保護被覆としての皮膜が厚い場合には内封された鰯
の魚臭漏洩が遮断されて摂取率が低下したり、消化性も
悪くなる傾向が見られる。この問題点は、本発明によれ
ば、投与に先立ち０２〜５．０チクエン酸ナトリウム水
溶液に浸漬して皮膜を軟化させることにより解決するこ
とができる。この処理のための所要時間Ｆｉ２０〜９０
分間であり、これにより魚臭が感知し得る程度に皮膜を
経て漏出するようになる。嗜好性を更に向上させるため
には例えばマグロエキスを用いることができ、これは上
記クエン酸ナトリウム溶液に添加されるのが好ましく、
マグロエキス濃度としては０．５チ程度が適当である。In addition, when the film as a protective coating is thick, leakage of the fishy odor of the encapsulated sardine is blocked, and there is a tendency for the intake rate to decrease and digestibility to deteriorate. This problem can be solved according to the invention by softening the film by immersion in an aqueous solution of 02-5.0 sodium citrate prior to administration. Required time for this process Fi20-90
minutes, which causes the fish odor to perceptibly leak through the film. To further improve palatability, for example, tuna extract can be used, which is preferably added to the sodium citrate solution,
A suitable concentration of tuna extract is about 0.5 inch.
（発明の効果）
本発明による薬剤の投与方法によれば投与時における薬
剤の流失をほぼ完全に回避することができるので、計算
量の薬剤を養殖魚に施与することができ、且つ薬剤が生
餌と一体となって施与されるのでその投薬率乃至摂取率
が著るしく向上すると請う効果がもたらされる。(Effects of the Invention) According to the method of administering a drug according to the present invention, it is possible to almost completely avoid spillage of the drug during administration, so that a calculated amount of the drug can be administered to the cultured fish, and the drug can be administered to the farmed fish in a calculated amount. Since it is administered together with live feed, it has the effect of significantly improving the dosage rate and intake rate.
薬剤を油脂類、凝固性蛋白又は燐脂質等で封入しておけ
はその薬効の失活を防止することができ、且つその保賎
被覆としての皮膜を形成するポリカチオン材料及びポリ
アニオン材料を適宜選択すれば、被覆生餌の冷凍及び解
凍にも充分に耐えることができるので、この種の生餌の
長期保存が可能となる効果がもたらされる。このことは
餌魚である鰯等をその水揚げ地において直ちに施薬−級
覆処理及び冷凍処理すれば、流通過程や解凍工程での雑
菌の増殖を防止することができ、従って養殖魚の罹病率
の低下にも役立つのである。Encapsulating the drug with fats and oils, coagulating proteins, phospholipids, etc. can prevent the drug from losing its efficacy, and appropriately selects polycationic and polyanionic materials that form a film that protects the drug. In this case, the coated live bait can sufficiently withstand freezing and thawing, so that this kind of live bait can be stored for a long period of time. This means that if feed fish such as sardines are subjected to chemical-grade coating and freezing treatment immediately at the landing site, it is possible to prevent the growth of various bacteria during the distribution and thawing processes, thereby reducing the morbidity rate of farmed fish. It is also useful.
（製造例及び試敗例）
次に製造例並びに薬物の流出性及び安定性に関する試験
例全貌明する。(Manufacturing Examples and Trial/Failure Examples) Next, the entire details of manufacturing examples and test examples regarding drug flowability and stability will be explained.
製造例１
市販の菜種油特殊硬化油４ｆとレシチン１２とを約６０
℃に加熱して溶融させ、これにビタミン類即ちチアミン
１０００１）＆、リボフラビン１５０ ｍ９、アスコル
ビン酸２０００１Ｒ２及びトコフェロール１２００単位
を添加して混合し、次いで冷却した後に乳鉢を用い粉砕
してビタミン含有粉末を調製した。Production example 1 Commercially available special hydrogenated rapeseed oil 4f and lecithin 12 were mixed at about 60%
℃ to melt it, add and mix vitamins, namely thiamine 10001) & riboflavin 150 m9, ascorbic acid 20001R2 and tocopherol 1200 units, and then cool it and crush it in a mortar to obtain a vitamin-containing powder. Prepared.
一方、５ｆのアルギン酸ナトリウムを含有する水溶液５
００−に、蔗糖ソルビタンエステル２．５２を添加し、
加熱して溶解させ、冷却後に前記のビタミン含有粉末を
全量（約９Ｆ）を添加して分散混合させる。On the other hand, aqueous solution 5 containing 5f sodium alginate
00-, add 2.52 sucrose sorbitan ester,
The mixture is heated to dissolve, and after cooling, the entire amount (approximately 9F) of the vitamin-containing powder is added and dispersed and mixed.
得たる溶液を噴霧器に装填し、新鮮な生鰯１０胸の表面
に均斉に噴霧した。噴霧溶液はアルギン酸ナトリウム成
分により粘性を呈しておシ且つ蔗糖ソルビタンエステル
成分は界面活性剤であるので魚体への付着性は極めて良
好であった。The resulting solution was loaded into a sprayer and sprayed evenly onto the surface of 10 fresh raw sardine breasts. The spray solution exhibited viscosity due to the sodium alginate component, and since the sucrose sorbitan ester component was a surfactant, it had extremely good adhesion to fish bodies.
噴霧処理の終了後に、１チの乳酸カルシウム及び０．５
−のキトサンとを含有する充分量（５〜２０ｔ）の水溶
液中に鰯を浸漬すれば上記アルギン酸ナトリウムとキト
サンとの反応により鰯表面には水に不溶性の皮膜が迅や
かに形成される。After the end of the spraying process, 1 g of calcium lactate and 0.5
- When sardines are immersed in a sufficient amount (5 to 20 tons) of an aqueous solution containing chitosan, a water-insoluble film is quickly formed on the surface of the sardines due to the reaction between the sodium alginate and chitosan.
このように処理された鰯を掬い上げ冷蔵庫に保存した。The sardines thus processed were scooped up and stored in a refrigerator.
この生餌は鮮度の観点から３日以内に養魚例えばハマチ
に投餌するのが好ましく、又投餌直前に、２％のクエン
酸ナトリウムと０．３％のマグロエキスとを含有する水
溶液内圧浸漬して上記皮膜を軟化させると共に養魚に対
する嗜好性を賦与するのが好ましい、
製造例２
市販の菜種油特殊硬化油１ｆを約６０℃に加熱して溶融
させ、これに抗生物質であるアンピシリン４００１ｒｖ
を添加して混合し、次いで冷却した後に乳鉢を用いて粉
砕して抗生物質含有粉末を調製した。From the viewpoint of freshness, it is preferable to feed this live bait to cultivated fish such as yellowtail within three days, and immediately before feeding, it is soaked in an aqueous solution containing 2% sodium citrate and 0.3% tuna extract under internal pressure. It is preferable to soften the film and impart palatability to fish farming. Production Example 2 Commercially available special hardened rapeseed oil 1f is heated to about 60°C to melt it, and ampicillin 4001rv, which is an antibiotic, is added to it.
was added and mixed, then cooled and ground using a mortar to prepare an antibiotic-containing powder.
一方、２Ｆのアルギン酸ナトリウムと３Ｆのカテル２Ｆ
を含有した６０℃の温水溶液１００−に上記抗生物質含
有粉末を手早く懸濁させｆＣ，懸濁液を１）１製し、こ
れらを２流体ノズル装置にそれぞれ装填して１０Ｋｐの
新鮮な主路の表面に均斉に噴霧し、次いで噴霧処理され
た鰯を塩化カルシウム及びポリリジンを各々１チ含有す
る水溶液中に直ちに浸漬した。１５〜３０分間浸漬すれ
ば、しっがシした皮膜が鰯表面に形成されるので、被覆
されたこの鰯を引上げて冷凍保存する。On the other hand, sodium alginate on 2F and catel 2F on 3F
The above antibiotic-containing powder was quickly suspended in a warm aqueous solution at 60°C containing fC. The sprayed sardines were then immediately immersed in an aqueous solution containing 1 g each of calcium chloride and polylysine. If the sardine is soaked for 15 to 30 minutes, a sticky film will be formed on the surface of the sardine, and the coated sardine is then pulled out and stored frozen.
本例によυ形成された皮膜は凍結耐性が高く−１０〜−
２０℃で保存することができ、従ってこの生餌の保存可
能期間は１年又はそれ以−ヒである。The film formed in this example has high freezing resistance of -10 to -
It can be stored at 20°C, so the shelf life of this live bait is one year or more.
解凍は１〜５チのクエン酸ナトリウム水溶液（常温）に
浸漬することにより行なうことができ、この浸漬処理に
より上記皮膜の軟化が生ずる。Thawing can be carried out by immersing in 1 to 5 liters of aqueous sodium citrate solution (at room temperature), and this immersion treatment causes the above-mentioned film to soften.
このようにして解凍された被覆鰯ＩＫｇを養魚例えば体
重Ｉ Ｋ９のハマチに与えれば、ハマチには３５〜４０
１ｖ／Ｋｆ相当量のアンピシリンが投与されることにな
る。If you feed Ikg of coated sardines thawed in this way to farmed fish, for example, yellowtail weighing IK9, the yellowtail will receive 35 to 40 kg of coated sardine.
An amount of ampicillin equivalent to 1v/Kf will be administered.
製造例３
製造例１に記載の方法でビタミン剤含有粉末を調製し、
これを新鮮な牛酪に塗した。これＫ、アルギン酸ナトリ
ウムと蔗糖ソルビタンエステルとを含有する溶液を噴霧
し、次いで製造例１と同様にして乳酸力・ルシウムとキ
トサンとを含有する溶液中に浸漬すれは水に不溶性の皮
膜が形成される。Production Example 3 A vitamin supplement-containing powder was prepared by the method described in Production Example 1,
This was applied to fresh cow's milk. This product was sprayed with a solution containing sodium alginate and sucrose sorbitan ester, and then immersed in a solution containing lactic acid, lucium, and chitosan in the same manner as in Production Example 1 to form a water-insoluble film. Ru.
本例において魚体への付着性を良好にするために、ビタ
ミン含有粉末の粒度は８０メツシユ又はそれ以下罠なさ
れる。In this example, the particle size of the vitamin-containing powder is 80 mesh or less in order to have good adhesion to the fish body.
製造例４
製造例２に記載の方法で抗生物質含有粉末を調製し、こ
れを新鮮な牛酪に塗した。この塗し処理した牛酪に、ア
ルギン酸ナトリウムとカッパー・カラギーナンとソルビ
タンエステルとを含有する溶液を噴霧し、次いで製造例
２と同様にして塩化カルシウムとポリリジンとを含有す
る溶液に浸漬すれば水に不溶性の皮膜が形成される。Production Example 4 An antibiotic-containing powder was prepared by the method described in Production Example 2, and applied to fresh cow milk. A solution containing sodium alginate, copper carrageenan, and sorbitan ester is sprayed onto the coated beef, and then immersed in a solution containing calcium chloride and polylysine in the same manner as in Production Example 2. A film is formed.
本例においても、魚体への付着性を良好にするために、
抗生物質含有粉末の粒度は８０メツシユ又はそれ以下に
なされる。In this example as well, in order to improve the adhesion to the fish body,
The particle size of the antibiotic-containing powder is made to be 80 mesh or less.
試験例１
ビタミン類の流出測定試験
製造例１に記載の方法に従って且つ皮膜形成剤として各
種物質を使用して被覆された鰯各ＩＫｆを海水１０を中
に浸漬し、浸漬直後及び６時間後に、最も溶出し易いア
スコルビン酸（ビタミ７ｃ）を対象としてその溶出量を
測定した。Test Example 1 Vitamin Efflux Measurement Test Each sardine IKf coated according to the method described in Production Example 1 and using various substances as film forming agents was immersed in 10% seawater, and immediately after immersion and 6 hours later, The elution amount of ascorbic acid (vitamin 7c), which is the most easily eluted, was measured.
その結果は、後記表１に示される通りであり、これから
アルギン酸ソーダのみを云わば糊として魚体にビタミン
Ｃを塗布した状態（対照区）では海水中への投入と同時
にその半量程度が流出してしまうこと並びに完全被覆鰯
（試験区）では６時間後にも約７０チ又はそれ以上のビ
タミンＣが流出することなしに保持されていることが判
る。尚、養魚がハマチである場合には投与から数分以内
に食べられてしまうので被覆生餌における実際のビタミ
ン流出は１０チ以下と推定される。The results are shown in Table 1 below, and it can be seen that when vitamin C was applied to the fish body using only sodium alginate as a glue (control group), about half of the amount leaked out when it was put into seawater. It can be seen that approximately 70 or more vitamin C is retained without leaking out even after 6 hours in the completely covered sardine (test group). In addition, if the farmed fish is yellowtail, it is eaten within a few minutes of administration, so the actual vitamin outflow from the coated raw bait is estimated to be less than 10.
試験例２
抗生物質及びビタミンの安定性試験
製造例２に記載の方法に従って皮膜が形成され且つ薬剤
としてアンピシリン（抗生物質）又はチアミン（ビタミ
ンＢ１）が用いられた被覆鰯を一１５℃で冷凍保存し、
これら薬剤の残存量変化をバイオ・アッセイ法により定
量した処、後記表２に示される通シの結果が得られ、こ
ハから１２ケ月の冷凍貯蔵期間を経た彼にもこれら薬剤
は充分安定に保持されていることが判る。Test Example 2 Stability test of antibiotics and vitamins Coated sardines, in which a film was formed according to the method described in Production Example 2 and ampicillin (antibiotic) or thiamine (vitamin B1) was used as the drug, were frozen and stored at -15°C. death,
When we quantified the changes in the residual amounts of these drugs using a bioassay method, we obtained the consistent results shown in Table 2 below, and after 12 months of frozen storage, these drugs were stable enough for him. It can be seen that it is retained.
手 続 補 正 書（自 発）１．事件の表示
昭和５９年特許顆第１５２１）２号
２、発明の名称
養殖魚への薬剤の投与方法
３、補正をする者
事件との関係 特許出願人
千葉県船橋市大穴町１９６−６
熊 部 潔
４、代理人 〒１０５
東京都港区虎ノ門１丁目１）醤７＠
５、補正の対象
明細−の「発明の詳細な説明」の−
６、補正の内容
（１）本願明細書第６員第３〜４行に「ＷＩ衆の作用」
とあるを「酸素の作用Ｊと補正する。Procedural amendment (voluntary) 1. Display of the case 1982 Patent Condyle No. 1521) No. 2, Name of the invention Method for administering drugs to cultured fish 3, Person making the amendment Relationship to the case Patent applicant Kumabe, 196-6 Oanacho, Funabashi City, Chiba Prefecture Kiyoshi 4, Agent 1-1 Toranomon, Minato-ku, Tokyo 105) Soy 7 @ 5. Detailed description of the invention in the specification to be amended - 6. Contents of the amendment (1) Sixth member of the specification of the present application Lines 3-4 indicate “the action of the WI crowd.”
It says, ``Correct it to the effect of oxygen J.
Claims (6)
り可食性の被覆を施こし、この被覆により薬剤を保護し
て投与することを特徴とする、養殖魚への薬剤の投与方
法。(1) A method for administering a drug to farmed fish, which comprises applying a water-insoluble and edible coating to the surface of raw fish or raw fish meat as feed, and administering the drug while protecting it with this coating. .
くとも１種であり、油脂、蛋白質又は燐脂質で封入され
ていることを特徴とする、特許請求の範囲第１項に記載
の投与方法。(2) The administration method according to claim 1, wherein the drug is at least one of vitamins, antibiotics, and hormones, and is encapsulated with oil, protein, or phospholipid.
オンとの反応により形成されたものであることを特徴と
する、特許請求の範囲第１又は２項に記載の投与方法。(3) The administration method according to claim 1 or 2, wherein the film as a protective coating is formed by a reaction between a polycation and a polyanion.
ンの少なくとも１種から選択され、ポリアニオンがカラ
ギーナン、アルギン酸、アルギン酸塩、ペクチン及びガ
ム類の少なくとも１種から選択されたものであることを
特徴とする、特許請求の範囲第３項に記載の投与方法。(4) A patent characterized in that the polycation is selected from at least one of chitosan, polylysine, and lecithin, and the polyanion is selected from at least one of carrageenan, alginic acid, alginate, pectin, and gums. The administration method according to claim 3.
水溶液に浸漬され、保護被覆としての皮膜が軟化されて
いることを特徴とする、特許請求の範囲第１〜５項の何
れか１つに記載の投与方法。(5) Any one of claims 1 to 5, characterized in that the film as a protective coating is softened by being immersed in a 0.2 to 5% aqueous sodium citrate solution prior to administration. Administration method as described in.
合されていることを特徴とする、特許請求の範囲第５項
に記載の投与方法。(6) The method of administration according to claim 5, characterized in that tuna extract is added to the sodium citrate solution.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP59152112A JPS6131045A (en) | 1984-07-24 | 1984-07-24 | Method of administering drug to cultivated fish |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP59152112A JPS6131045A (en) | 1984-07-24 | 1984-07-24 | Method of administering drug to cultivated fish |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS6131045A true JPS6131045A (en) | 1986-02-13 |
Family
ID=15533317
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP59152112A Pending JPS6131045A (en) | 1984-07-24 | 1984-07-24 | Method of administering drug to cultivated fish |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6131045A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0292243A (en) * | 1988-09-27 | 1990-04-03 | Itochu Shiryo Kk | Production of feed for the young of fishes |
| JPH02207759A (en) * | 1989-02-07 | 1990-08-17 | Suisan Kagaku Kk | Artificial feed for culture of aquatic animal |
| JPH0315329A (en) * | 1988-10-10 | 1991-01-23 | Israel Oceanographic & Limnological Res Ltd | Composition for controlling reproduction of fish and controlling spawn of fish |
| WO2003080127A1 (en) * | 2002-03-27 | 2003-10-02 | Dag Arntsen | Method and apparatus for antibacterial sanitation treatment of rooms and objects |
| WO2003086099A1 (en) * | 2002-04-18 | 2003-10-23 | Showa Denko K.K. | Fish-farming solid feed and process for producing same |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5239758A (en) * | 1975-09-25 | 1977-03-28 | Mitsubishi Heavy Ind Ltd | Resin mixing screw |
| JPS5378986A (en) * | 1976-12-23 | 1978-07-12 | Dainippon Toryo Co Ltd | Pigment-attached fluorescent substance and production thereof |
| JPS5754560A (en) * | 1980-09-20 | 1982-04-01 | Kunitsugu Kitabayashi | Preparation of feed for aquatic animal |
| JPS5963147A (en) * | 1982-10-05 | 1984-04-10 | Marine Project:Kk | Modification of pisciculture feed |
| JPS5966844A (en) * | 1982-10-12 | 1984-04-16 | Riken Vitamin Co Ltd | Live bait feed composition for fish farming |
-
1984
- 1984-07-24 JP JP59152112A patent/JPS6131045A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5239758A (en) * | 1975-09-25 | 1977-03-28 | Mitsubishi Heavy Ind Ltd | Resin mixing screw |
| JPS5378986A (en) * | 1976-12-23 | 1978-07-12 | Dainippon Toryo Co Ltd | Pigment-attached fluorescent substance and production thereof |
| JPS5754560A (en) * | 1980-09-20 | 1982-04-01 | Kunitsugu Kitabayashi | Preparation of feed for aquatic animal |
| JPS5963147A (en) * | 1982-10-05 | 1984-04-10 | Marine Project:Kk | Modification of pisciculture feed |
| JPS5966844A (en) * | 1982-10-12 | 1984-04-16 | Riken Vitamin Co Ltd | Live bait feed composition for fish farming |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0292243A (en) * | 1988-09-27 | 1990-04-03 | Itochu Shiryo Kk | Production of feed for the young of fishes |
| JPH0315329A (en) * | 1988-10-10 | 1991-01-23 | Israel Oceanographic & Limnological Res Ltd | Composition for controlling reproduction of fish and controlling spawn of fish |
| JPH02207759A (en) * | 1989-02-07 | 1990-08-17 | Suisan Kagaku Kk | Artificial feed for culture of aquatic animal |
| WO2003080127A1 (en) * | 2002-03-27 | 2003-10-02 | Dag Arntsen | Method and apparatus for antibacterial sanitation treatment of rooms and objects |
| WO2003086099A1 (en) * | 2002-04-18 | 2003-10-23 | Showa Denko K.K. | Fish-farming solid feed and process for producing same |
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