JPS61236632A - Crystallized glass for organism - Google Patents

Crystallized glass for organism

Info

Publication number
JPS61236632A
JPS61236632A JP60067272A JP6727285A JPS61236632A JP S61236632 A JPS61236632 A JP S61236632A JP 60067272 A JP60067272 A JP 60067272A JP 6727285 A JP6727285 A JP 6727285A JP S61236632 A JPS61236632 A JP S61236632A
Authority
JP
Japan
Prior art keywords
glass
crystallized glass
noble metal
organism
temp
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP60067272A
Other languages
Japanese (ja)
Inventor
Takehiro Shibuya
武宏 渋谷
Yoshio Hashibe
吉夫 橋部
Masataka Takagi
雅隆 高木
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Electric Glass Co Ltd
Original Assignee
Nippon Electric Glass Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Electric Glass Co Ltd filed Critical Nippon Electric Glass Co Ltd
Priority to JP60067272A priority Critical patent/JPS61236632A/en
Publication of JPS61236632A publication Critical patent/JPS61236632A/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C4/00—Compositions for glass with special properties
    • C03C4/0007—Compositions for glass with special properties for biologically-compatible glass
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C10/00—Devitrified glass ceramics, i.e. glass ceramics having a crystalline phase dispersed in a glassy phase and constituting at least 50% by weight of the total composition
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C3/00—Glass compositions
    • C03C3/04—Glass compositions containing silica
    • C03C3/062—Glass compositions containing silica with less than 40% silica by weight
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C3/00—Glass compositions
    • C03C3/04—Glass compositions containing silica
    • C03C3/062—Glass compositions containing silica with less than 40% silica by weight
    • C03C3/064—Glass compositions containing silica with less than 40% silica by weight containing boron
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C3/00—Glass compositions
    • C03C3/04—Glass compositions containing silica
    • C03C3/076—Glass compositions containing silica with 40% to 90% silica, by weight
    • C03C3/097—Glass compositions containing silica with 40% to 90% silica, by weight containing phosphorus, niobium or tantalum

Abstract

PURPOSE:To obtain the titled glass which is excellent in the organism affinity and the mechanical strength and chemically bonded to a bone directly by incorporating noble metal of the proper amount as a nucleus forming agent in glass having P2O5, CaO, SiO2 and MgO of the specified composition as an essential component. CONSTITUTION:The crystallized glass for an organism is obtained by incorporating 0.1-1,000ppm one and more kinds of noble metal of Ag, Au, Pt, Pd and Rh, etc. as a nucleus forming agent for glass wherein by weight at least >=80% consists of 1-30% P2O5, 20-53% CaO, 20-56% SiO2, 1-20% MgO and <=20% impurities consisting of one and more kinds of Li2O, Na2O, K2O, SrO, B2O3, Al2O3, Nb2O5 and Ta2O5 is incorporated therein. The above-mentioned glass is molded by weighting the raw material so as to obtain the above-mentioned prescribed composition and mixing these and furthermore adding noble metal as oxide or halide and heating the above-mentioned mixture to melt it and flowing it into a casting mold. Then after the molded article is risen in temp. in about 30-150 deg.C/hr and held at about 900-1,100 deg.C for about 1-3hr, it is descended in temp. up to room temp. in about 60-150 deg.C/hr and obtained by crystallizing the glass.

Description

【発明の詳細な説明】 本発明は、人工骨や人工歯科材料として有用な生体用結
晶化ガラスに関するものである。DETAILED DESCRIPTION OF THE INVENTION The present invention relates to a biological crystallized glass useful as an artificial bone or artificial dental material.

従来、人工骨や歯科材料としては、銀、タンタル等の金
属材料、コバルトタロム合金、チタン合金、ステンレス
等の合金材料、ポリメチルメタクリレート、高密度ポリ
エチレン等の高分子イＡＩ′４、アルミナセラミックス
、合成アパタイト等のセラミックス材料が用いられてき
た。しかしながら金属、合金材料は強度的には優れてい
るが、生体組織との親和性が悪く、長期間人体中で使用
ず°ると金属イオンが溶は出し、生体組織を害する恐れ
があり、又高分子材料は生体内で安定するが、強度が弱
く骨と化学結合せず、ごく限られた部分にしか使用でき
ない上、製造時に未反応で残ったモノマーが溶出して生
体組織を損う恐れがあった。さらにアルミナセラミック
スは、強度的には優れているが骨と化学結合せず、逆に
合成アパタイトは骨と強固に結合はするが、強度が低い
という問題があった。Conventionally, artificial bones and dental materials include metal materials such as silver and tantalum, alloy materials such as cobalt-talom alloy, titanium alloy, and stainless steel, polymeric AI'4 such as polymethyl methacrylate and high-density polyethylene, alumina ceramics, Ceramic materials such as synthetic apatite have been used. However, although metals and alloy materials have excellent strength, they have poor affinity with living tissue, and if they are not used in the human body for a long period of time, metal ions may be dissolved and harm living tissue. Polymer materials are stable in vivo, but their strength is weak and they do not chemically bond with bones, so they can only be used in very limited areas, and there is a risk that unreacted monomers that remain during manufacturing may elute and damage living tissue. was there. Furthermore, although alumina ceramics have excellent strength, they do not chemically bond with bone, and synthetic apatite, on the other hand, strongly bonds with bone but has a problem of low strength.

本発明は、上記欠点を解消すべくなされたもので、人工
骨や入玉歯科組材として生体親和性に優れ、骨と直接化
学結合をつくり、しかも機械強度においても優れた生体
用結晶化ガラスを提供することを目的とするものである
。The present invention has been made in order to eliminate the above-mentioned drawbacks, and is a biological crystallized glass that has excellent biocompatibility as an artificial bone or ball-filled dental assembly material, creates a direct chemical bond with bone, and has excellent mechanical strength. The purpose is to provide the following.

本発明の生体用結晶化ガラスは、重量％て少なくとも８
０％以−ヒがＰｏｎ５１〜３０％、ＣａＯ２０〜５３％
、５ｉ０２２０〜５６％、Ｍｇｆｌ　１〜２０％からな
り、不純物２０％以下よりなる組成を有するガラスに対
して核形成剤としてＡｇ１ＡＵＩＰｔ、Ｐｄ、Ｒｈ等の
貴金属の何れか１種又は２種以」−を０．１〜１００Ｏ
ｐρｍ含有することを特徴とする。The living body crystallized glass of the present invention is at least 8% by weight.
0% or more Pon51-30%, CaO20-53%
, 5i020 to 56%, Mgfl 1 to 20%, and any one or two or more of noble metals such as Ag1AUIPt, Pd, and Rh as a nucleating agent for glass having a composition of 20% or less of impurities. 0.1~100O
It is characterized by containing pρm.

また本発明の生体用結晶化ガラスは、１ｉｚＯ。Moreover, the biological crystallized glass of the present invention is 1izO.

Ｎａｚｌｌ　、ＫｚＯ，ＳｒＯ，Ｂａｎ５．Ａｌｚ（’
ｉ３．Ｎｂ２Ｏ５，ＴａｚＯｓの何れか１種又は２種以
−Ｌを２０重量％以下不純物として含有することを特徴
とする。Nazll, KzO, SrO, Ban5. Alz('
i3. It is characterized by containing 20% by weight or less of one or more of Nb2O5 and TazOs as an impurity.

本発明による生体用結晶化ガラスは、核形成剤として添
加される貴金属によって結晶化が促進され、ガラス内に
均一・に結晶が析出する。析出する結晶は、アパタイト
、ウオラスナイト、ジオプサイドの３結晶であり、アパ
タイト結晶は、結晶化ガラスと骨の間に化学結合を生じ
させると共に生体親和性を良好にし、ウオラストナイト
、ジオプサイド結晶は、結晶化ガラスの機械的強度を高
める作用をもたらす。また３種の相互作用によって結晶
化ガラスの機械加工性も良好になる。In the biological crystallized glass according to the present invention, crystallization is promoted by the noble metal added as a nucleating agent, and crystals are uniformly precipitated within the glass. The three crystals that precipitate are apatite, wollastonite, and diopside.Apatite crystals create a chemical bond between crystallized glass and bone and have good biocompatibility, while wollastonite and diopside crystals It has the effect of increasing the mechanical strength of chemically modified glass. The interaction of the three types also improves the machinability of the crystallized glass.

本発明の生体用結晶化ガラスの組成範囲を前記のように
限定したのは次の理由による。The reason why the composition range of the living body crystallized glass of the present invention is limited as described above is as follows.

Ｐ２Ｏ５が１％より少ない場合は、リン酸カルシウム系
結晶であるアパタイトの析出量が少量となり、生体親和
性が悪くなり、３０％より多い場合には失透性が強くな
り少量のウオラストナイト結晶しか析出しない。If P2O5 is less than 1%, a small amount of apatite, which is a calcium phosphate crystal, will be precipitated, resulting in poor biocompatibility; if it is more than 30%, devitrification will be strong and only a small amount of wollastonite crystals will be precipitated. do not.

ＣａＯが２０％より少ない場合には、結晶化度が低くな
りアパタイト、ウオラストナイト結晶が少量しか析出せ
ず、５３％より多い場合には失透性が高くなり、ガラス
化が困難となる。When CaO is less than 20%, the degree of crystallinity is low and only a small amount of apatite and wollastonite crystals are precipitated, and when it is more than 53%, devitrification becomes high and vitrification becomes difficult.

５１０２が２０％より少ない場合には、失透性が高く、
ガラスの溶解、成形が困難となると同時にウオラストナ
イト結晶の析出も少量となり、５６％より多い場合には
ガラスの粘度が高くなりガラスの溶解が困難になると同
時にアパタイト結晶の析出量が減る。When 5102 is less than 20%, devitrification is high,
It becomes difficult to melt and shape the glass, and at the same time, a small amount of wollastonite crystals are precipitated.If the amount exceeds 56%, the viscosity of the glass becomes high, making it difficult to melt the glass, and at the same time, the amount of apatite crystals precipitated decreases.

ＭｇＯが１％より少ない場合には、失透性が高く溶融ガ
ラスのガラス化が困難であると同時にジオプサイド結晶
の析出量が少なくなり、２０％より多い場合には、結晶
化速度が遅くなり結晶化度、機械的強度が低くなる。When MgO is less than 1%, the devitrification is high and it is difficult to vitrify the molten glass, and at the same time, the amount of diopside crystals precipitated is small, and when it is more than 20%, the crystallization rate is slow and crystals are not formed. The degree of corrosion and mechanical strength decrease.

更に、上記成分以外にも２０重量％以下の量の１．１２
ｆｌ、ＮａｚＯ２ＫｚＯ，ＳｒＯ，ＢｚＯｘ、ＡＩｚＯ
ｓ、ＮｂｚＯｉ、Ｔａｚ軸のいずれか１種又は２種以り
を含有することが可能である。ただし、これらの添加成
分の合計が２０％より多い場合には、析出結晶の結晶量
や種類が変化したり、機械的強度や機械加工性が低下【
）たりして好ま【ノ〈ない。Furthermore, in addition to the above components, 1.12 in an amount of 20% by weight or less
fl, NazO2KzO, SrO, BzOx, AIzO
It is possible to contain one or more of s, NbzOi, and Taz axes. However, if the total amount of these additive components exceeds 20%, the amount and type of precipitated crystals may change, and mechanical strength and machinability may decrease.
) and like it.

また、本発明は、結晶化を促進させガラス内に均・に結
晶核を生成する核形成剤として、貴金属を０．１〜１１
０００ｐｐ含むが、該貴金属の含有量が０、ｌｐｐｍよ
り少ない場合は、均一・な核形成がおきず結晶粒子径が
大きくなり、しかも結晶のサイズが不均等になるため、
所望の結晶化ガラスを得ることが困難となる。一方１１
０００ｐｐより多い場合は、失透速度が早くなりすぎて
ガラス化が困難となる。In addition, the present invention uses a precious metal of 0.1 to 11
000ppm, but if the content of the noble metal is less than 0.1ppm, uniform nucleation will not occur and the crystal grain size will increase, and the crystal size will become uneven.
It becomes difficult to obtain the desired crystallized glass. On the other hand 11
If it exceeds 000 pp, the devitrification rate becomes too fast and vitrification becomes difficult.

本発明の生体用結晶化ガラスは、例えば次のように製造
される。The living body crystallized glass of the present invention is manufactured, for example, as follows.

常法により所望の組成になるように原料を秤量し、それ
を混合しガラス溶融炉において溶解する。The raw materials are weighed using a conventional method to obtain the desired composition, mixed, and melted in a glass melting furnace.

溶解後、溶融ガラスを鋳造型の中に流し込むか必要に応
じて圧入、遠心鋳造することにより所望の形状に成形す
る。次いでこの成形品を電気炉中にまで降温することに
よってガラスを結晶化する。After melting, the molten glass is poured into a casting mold or, if necessary, press-fitted or centrifugally cast to form a desired shape. Next, the temperature of this molded article is lowered into an electric furnace to crystallize the glass.

このように本発明の生体用結晶化ガラスでは、溶融ガラ
スをいったん粉砕し、この粉体物から新めて所望の形状
に成形する必要がなく、核形成剤として貴金属を含有す
るために溶融ガラスをそのまま鋳造して成形することが
でき、次の結晶化熱処理によってガラス内に均一に結晶
を析出させた強度の高い結晶化ガラスが得られる。含有
する責金属は、Ａｇ、Ａｕ、ＰＬ、Ｐｄ、Ｒｂ等であり
、ハ？、’１４として混合゛４る際には、それの酸化物
、ハロゲン化物が用いられる。In this way, the biological crystallized glass of the present invention does not require the need to once crush molten glass and then mold the powder into a new desired shape. The glass can be cast and shaped as it is, and the subsequent crystallization heat treatment yields a high-strength crystallized glass in which crystals are uniformly precipitated within the glass. The responsible metals contained are Ag, Au, PL, Pd, Rb, etc. , '14, and their oxides and halides are used.

以下実施例に基づいて本発明を説明する。The present invention will be explained below based on Examples.

試料Ｎα４のカラス組成になるようにバッチを調合し、
ガラス溶融炉中で１４５０℃で３時間溶解する。Prepare a batch to have the glass composition of sample Nα4,
Melt in a glass melting furnace at 1450° C. for 3 hours.

次にできた溶融カラスを金型の中に流し込んで１０Ｘ　
Ｉ　ＯＸ　５０ｍｍの角棒を成形し、この成形品を電気
炉中で１２０℃／時で常温より昇流し、１０５０°Ｃで
２時間保持した後、１２０℃／時で常温まで降温するこ
とによってカラスを結晶化する。Next, pour the molten glass into the mold and give it a 10X
I OX A square bar of 50 mm was molded, and the molded product was heated up from room temperature at 120°C/hour in an electric furnace, held at 1050°C for 2 hours, and then cooled to room temperature at 120°C/hour. crystallize.

得られた結晶化ガラスは、アパタイト、ウオラストナイ
ト及びその他の結晶を緻密に析出している。こう【ノて
てきた結晶化ガラスをＩＯＸ　１５Ｘ　２　ｎｕｎの板
状に９口りし兎の大腿部に挿入し、８週間経過した後も
生体に対し何らの害も示さず、自然骨の接着性も良好で
あった。The obtained crystallized glass has apatite, wollastonite, and other crystals precipitated in a dense manner. [The prepared crystallized glass was cut into 9 plates of IOX 15X 2 nun and inserted into the thigh of a rabbit, and even after 8 weeks had passed, there was no harm to the living body, and the natural bone remained intact. Adhesion was also good.

以」二のように本発明の生体用結晶化ガラスは、生体組
織との親和性に優れ、骨と化学結合すると共に機械的強
度も高いので人工骨、人工歯根、人工歯冠等の生体用材
料として有用である。また鋳造法によって成形できるた
め、製造工程を簡素化できると共に生産コストも軽減す
ることができる。As mentioned above, the living body-use crystallized glass of the present invention has excellent affinity with living tissues, chemically bonds with bones, and has high mechanical strength, so it can be used for living things such as artificial bones, artificial tooth roots, and artificial tooth crowns. Useful as a material. Furthermore, since it can be molded by a casting method, the manufacturing process can be simplified and production costs can be reduced.

−〇− 手続補正書 昭和６１年　５月　６日 １、事件の表示 昭和６０年特許願第６７２７２号 ２、発明の名称 生体用結晶化ガラス ３、補正をする者 事件との関係　　特許出願人 ４、補正命令の日付　　　　自発補正 ６、補正の内容 発明の詳細な説明 ■明細書箱３頁２０行目 「・・・ウォラスナイ１へ　・・・」を［・・ウォラス
トナイ）・　・・・−１に訂正する。-〇- Procedural amendment May 6, 1985 1, Indication of the case 1985 Patent Application No. 67272 2, Name of the invention Crystallized glass for living organisms 3, Person making the amendment Relationship to the case Patent applicant 4 , Date of amendment order Voluntary amendment 6, Contents of amendment Detailed explanation of the invention ■Specification box page 3, line 20, "...to Wollasunai 1..." to [... Wollasunai)...-1] correct.

Claims (2)

【特許請求の範囲】[Claims] （１）重量％で少なくとも８０％以上がＰ＿２Ｏ＿５　
１〜３０％、ＣａＯ　２０〜５３％、ＳｉＯ＿２　２０
〜５６％、ＭｇＯ　１〜２０％からなり、不純物２０％
以下よりなる組成を有するガラスに対して、核形成剤と
してＡｇ、Ａｕ、Ｐｔ、Ｐｄ、Ｒｈ等の貴金属の何れか
が１種又は２種以上を０．１〜１０００ｐｐｍ含有する
ことを特徴とする生体用結晶化ガラス。(1) At least 80% by weight is P_2O_5
1-30%, CaO 20-53%, SiO_2 20
~56%, MgO 1-20%, impurities 20%
A glass having the following composition contains one or more noble metals such as Ag, Au, Pt, Pd, and Rh as a nucleating agent in an amount of 0.1 to 1000 ppm. Crystallized glass for biological use. （２）Ｌｉ＿２Ｏ、Ｎａ＿２Ｏ、Ｋ＿２Ｏ、ＳｒＯ、Ｂ
＿２Ｏ＿３、Ａｌ＿２Ｏ＿３、Ｎｂ＿２Ｏ＿５、Ｔａ＿
２Ｏ＿５の何れか１種又は２種以上を２０重量％以下不
純物として含有する特許請求の範囲第１項記載の生体用
結晶化ガラス。(2) Li_2O, Na_2O, K_2O, SrO, B
_2O_3, Al_2O_3, Nb_2O_5, Ta_
The biological crystallized glass according to claim 1, which contains 20% by weight or less of any one or more of 2O_5 as an impurity.
JP60067272A 1985-03-29 1985-03-29 Crystallized glass for organism Pending JPS61236632A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP60067272A JPS61236632A (en) 1985-03-29 1985-03-29 Crystallized glass for organism

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP60067272A JPS61236632A (en) 1985-03-29 1985-03-29 Crystallized glass for organism

Publications (1)

Publication Number Publication Date
JPS61236632A true JPS61236632A (en) 1986-10-21

Family

ID=13340156

Family Applications (1)

Application Number Title Priority Date Filing Date
JP60067272A Pending JPS61236632A (en) 1985-03-29 1985-03-29 Crystallized glass for organism

Country Status (1)

Country Link
JP (1) JPS61236632A (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6311545A (en) * 1986-06-30 1988-01-19 Kyocera Corp Calcium phosphate crystallized glass body
JPS63174909A (en) * 1987-01-09 1988-07-19 Nippon Electric Glass Co Ltd Tooth model and production thereof
FR2612918A1 (en) * 1985-09-26 1988-09-30 Nippon Electric Glass Co BIOCOMPATIBLE VITROCERAMIC, NOT CONTAINING ALKALINE, OR MIXED WITH APATITE, WOLLASTONITE AND CRYSTAL DIOPSIDE
JPH01171560A (en) * 1987-12-28 1989-07-06 Kyocera Corp Calcium phosphate system crystallizing glass for organism
CN103848574A (en) * 2012-12-06 2014-06-11 上海诺帮生物科技有限公司 Preparation of strontium-containing bioglass powder and preparation method of strontium-containing porous bioglass bracket

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS608985A (en) * 1983-06-29 1985-01-17 インタ−ナショナル　ビジネス　マシ−ンズ　コ−ポレ−ション Laplace operator function apparatus

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS608985A (en) * 1983-06-29 1985-01-17 インタ−ナショナル　ビジネス　マシ−ンズ　コ−ポレ−ション Laplace operator function apparatus

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2612918A1 (en) * 1985-09-26 1988-09-30 Nippon Electric Glass Co BIOCOMPATIBLE VITROCERAMIC, NOT CONTAINING ALKALINE, OR MIXED WITH APATITE, WOLLASTONITE AND CRYSTAL DIOPSIDE
JPS6311545A (en) * 1986-06-30 1988-01-19 Kyocera Corp Calcium phosphate crystallized glass body
JPS63174909A (en) * 1987-01-09 1988-07-19 Nippon Electric Glass Co Ltd Tooth model and production thereof
JPH01171560A (en) * 1987-12-28 1989-07-06 Kyocera Corp Calcium phosphate system crystallizing glass for organism
CN103848574A (en) * 2012-12-06 2014-06-11 上海诺帮生物科技有限公司 Preparation of strontium-containing bioglass powder and preparation method of strontium-containing porous bioglass bracket

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