JPS604861A - Automatic analytical apparatus - Google Patents
Automatic analytical apparatusInfo
- Publication number
- JPS604861A JPS604861A JP11244283A JP11244283A JPS604861A JP S604861 A JPS604861 A JP S604861A JP 11244283 A JP11244283 A JP 11244283A JP 11244283 A JP11244283 A JP 11244283A JP S604861 A JPS604861 A JP S604861A
- Authority
- JP
- Japan
- Prior art keywords
- turret
- reaction tube
- predetermined
- diluent
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/025—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having a carousel or turntable for reaction cells or cuvettes
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
Description
【発明の詳細な説明】
この発明は、自動分析装置に係わり、特に免疫分析に好
適な自動分析装置に関する。DETAILED DESCRIPTION OF THE INVENTION The present invention relates to an automatic analyzer, and particularly to an automatic analyzer suitable for immunoassay.
この発明の目的とする点は、第１には、免役自動分析に
おいて所望倍率まで検体を測定項目に対応して希釈する
作業を確実かつ高精度に行うこと、第２には同分析にお
いて生起する凝集反応を均一となすため、攪拌全瞬時に
処理することで測定データに対する信頼性を大幅に向上
すること、第３にはこれらの各目的を簡易な装置で行な
い小型でｊ兼価な自動分析装置を提供することにある。The objectives of this invention are, firstly, to perform the work of diluting a sample to a desired magnification in accordance with the measurement item in automatic immunoassay analysis reliably and with high precision, and secondly, to In order to make the aggregation reaction uniform, the reliability of the measurement data is greatly improved by instantaneous stirring, and thirdly, each of these purposes can be accomplished with a simple device, allowing for compact and versatile automatic analysis. The goal is to provide equipment.
これらの目的を同時に達成するため、この発明にあって
は、自動分析装置Ｎ、を、所要分析項目に必要な希釈液
を収容してなる複数個の容器をターレット状ホルダーに
放射状に保持し、該ホルダーは所望希釈液全対応反応管
に所定位置で注入し得るよう駆動装置で移送制御されて
おり、かつ同ホルダーの外周に配設されたターレット状
の保持装置には、」二記反応管がａ数本所要間隔毎に保
持され、同装置は駆動装置で所定回動されるよう駆動制
御されてなるターレット装置全所要間隔離間させて一対
並設し、一方のターレット装置における反応管には、検
体秤取分注装置でザンブラー内より秤取された検体が所
定位置で注入きれ、この後同反応管には分析項目に対応
する希釈７１１がＨ「要址注入され所定希釈倍率に希釈
された後ピペット装置の秤取部位まで移送されるように
駆動制御されていると共に、他のターレット装置におけ
る反応管は、ピペット装置で所要量秤取された所定希釈
倍率の検体が所要量分注された後、分析項目に対応して
更に第２のターレット装置における希釈液が所要量圧入
されることで所定希釈倍率寸で希釈され、この後同反応
管は攪拌位置まで回動制御され、同位置で所定攪拌が行
なわれた後、前記保持装置は同反応管を上記ピペット装
置による所定希釈倍率の検体注入位置より−ポジション
進んだ間歇移動位置までスキャン作動するよう回動制御
され、同スキャン作動中に検体の比色測定を光学装置で
行なうよう構成したものである。In order to simultaneously achieve these objectives, in the present invention, the automatic analyzer N has a plurality of containers containing diluents necessary for required analysis items held radially in a turret-like holder, The transfer of the holder is controlled by a drive device so that the desired diluent can be injected into all reaction tubes at a predetermined position, and a turret-shaped holding device disposed around the holder has a turret-like holding device that is capable of injecting all the desired diluents into reaction tubes at predetermined positions. A number of turrets are held at required intervals, and this device is controlled by a drive device so that they rotate at a predetermined distance.All of the turret devices are installed in parallel with each other separated by a required distance, and the reaction tubes in one turret device are The sample weighed from inside the tumbler by the sample weighing and dispensing device is injected at a predetermined position, and then the dilution 711 corresponding to the analysis item is injected into the same reaction tube and diluted to a predetermined dilution ratio. The reaction tube in the other turret device is controlled so that the required amount of the sample at a predetermined dilution ratio is dispensed into the reaction tube in the other turret device. After that, the required amount of diluent is injected into the second turret device according to the analysis item to dilute it at a predetermined dilution ratio, and then the reaction tube is controlled to rotate to the stirring position, and then the reaction tube is rotated to the stirring position. After predetermined stirring is performed at , the holding device is rotationally controlled so as to scan the reaction tube to an intermittent movement position that is one position ahead of the position where the sample at a predetermined dilution ratio is injected by the pipette device, and during the scanning operation. The system is configured to perform colorimetric measurement of a specimen using an optical device.
以下、添付図面に示す実施例にもとづき、この発明の詳
細な説明する。Hereinafter, the present invention will be described in detail based on embodiments shown in the accompanying drawings.
図においてＤＩ 、Ｄ２は所要間隔離間して並設された
ターレット装置全示し、これらの装置ＤＩ。In the figure, DI and D2 indicate all the turret devices installed in parallel with a required distance, and these devices DI.
株は夫々、所要分析項目に必要な希釈液Ｒ１，Ｒ２を収
容してなる複数個の容器Ｂｌ、Ｂ２が放射状に保持され
たターレット状ホルダｌ 、 １’と、同ポホルダ１，
１′と同心状に配設され、複数本の反応管２，２０が所
定間隔毎に離間して保持されてなる保持装置Ｈ１、Ｒ２
と、これらの保持装置Ｈ１゜Ｒ２及びターレット状ホル
ダｉ 、 ｉ’ｌ夫々回動制御する各駆動装置Ｍｌ 、
Ｍ２ 、 Ｍ３． Ｍ４とから構成されている。Each strain is divided into turret-shaped holders 1 and 1' in which a plurality of containers B1 and B2 containing diluents R1 and R2 required for required analysis items are held in a radial manner, and turret-shaped holders 1 and 1' respectively.
Holding devices H1 and R2 are arranged concentrically with H1' and hold a plurality of reaction tubes 2 and 20 spaced apart from each other at predetermined intervals.
and each drive device Ml that controls the rotation of these holding devices H1°R2 and turret-shaped holders i and i'l, respectively.
M2, M3. It is composed of M4.
ターレット装置Ｄｌに保持された反応管２には、所定位
置で、オートサンプラー３の各サンプラー４内に収容さ
れた検体が検体秤取分注装置５で所要量秤取されたもの
が分注されて駆動装置Ｍｌで間歇移送される。尚オート
サンプラー３は、反応管２の間歇回動に同期してサンプ
ルカセットが公知の機構で間歇移送されるよう構成され
ている。そして、所望の検体が所要量分注された反応管
２は前記保持装置Ｈ１を介して上述のように間歇移送さ
れて希釈液分往信ＩＲまで到来し、該位置では同反応管
２に分析項目に対応する第１希釈液Ｒ１（反応安定希釈
液）が所要量分注されて所定倍率、例えば約４０倍の濃
度に希釈される。つまり同位置に反応管２が到来すると
、予じめ同反応管２内の検体に対する分析項目が入力さ
れている制御装置（ＣＰＵ）は、駆動装置Ｍ２を駆動制
御してターレント状ホルダーｉ２高速回動じ、分析項目
に対応する希釈液Ｒ１が収容されてなる容器Ｂｌが上記
希釈液分注位置まで移送される。尚、この各容器Ｂｌは
、予じめその内容種別が制御装置（ＣＰＵ）に人力され
ているとともに、そのポジションは公知の読取装置（例
えばセンツー−等）により常に読み取られ上記制御（Ｃ
ＰＵ）にその都度入力されている。A required amount of the sample contained in each sampler 4 of the autosampler 3 is weighed by the sample weighing and dispensing device 5 and dispensed into the reaction tube 2 held in the turret device Dl at a predetermined position. and is intermittently transferred by a drive device Ml. The autosampler 3 is configured so that the sample cassette is intermittently transferred by a known mechanism in synchronization with the intermittent rotation of the reaction tube 2. Then, the reaction tube 2 into which the required amount of the desired specimen has been dispensed is intermittently transferred via the holding device H1 as described above and reaches the diluted liquid outbound IR, where the reaction tube 2 is filled with the analysis item. A required amount of the first diluent R1 (reaction stable diluent) corresponding to the reaction is dispensed and diluted to a predetermined magnification, for example, about 40 times the concentration. In other words, when the reaction tube 2 arrives at the same position, the control device (CPU), into which the analysis items for the sample in the reaction tube 2 have been inputted in advance, drives and controls the drive device M2 to rotate the talent-shaped holder i2 at high speed. Then, the container B1 containing the diluent R1 corresponding to the analysis item is transferred to the diluent dispensing position. Note that the content type of each container Bl is manually entered in advance by the control device (CPU), and its position is always read by a known reading device (for example, Sentsu etc.) and the above-mentioned control (C
PU) each time.
このように希釈液分注位置に所要の容器が移送停止され
、反応管２も同位置で停止するのと同期して希釈液ピペ
ットが作動して容器Ｂ１内から所斐量の第１希釈液Ｒ１
が秤取され同反応管２に分注されて上記希釈が行なわれ
る。In this way, the required container is transferred and stopped at the diluent dispensing position, and the reaction tube 2 is also stopped at the same position. At the same time, the diluent pipette is operated and a predetermined amount of the first diluent is dispensed from the container B1. R1
is weighed out and dispensed into the same reaction tube 2 to perform the above dilution.
すなわち、上記各容器Ｂｌの後方には、ポンプ６と、こ
のポンプ６に接続され、伸縮可能に保持賂ノｔてｌるピ
ペットチューブ（図示省略）と、このピペットチューブ
の先端に接続されたビベット（図示せず）とからなり、
同ポ／プロは、所定位置で井≠略椿＃裔正逆回転可能な
カム８の突起と係合し下降することで所定量の第１希釈
液Ｒ】が吸引された後、カム８はポンプ６との係合を解
除して中立位置へと復動する。すると、把持装置７のア
ームが伸張して上記ピペットが把持されることで同ピペ
ットは器外へと引き出されて反応管２内へと案内され、
この後第１希釈液は第２カム９の上昇によりピペットよ
り反応管２内へと所要量分注されるのである。この後、
把持装置７がピペットの把持を中止すると、バネ叫の手
段によυ同ピペットは部位１ｄへと復動し、上記希釈液
分注作動は終了する。That is, at the rear of each container Bl, there is a pump 6, a pipette tube (not shown) that is connected to the pump 6 and is extendable and retractable, and a bivet connected to the tip of the pipette tube. (not shown)
At a predetermined position, the po/pro engages with the protrusion of the cam 8, which can be rotated in forward and reverse directions, and descends. After a predetermined amount of the first diluent R is sucked, the cam 8 It disengages from the pump 6 and moves back to the neutral position. Then, the arm of the gripping device 7 extends and grips the pipette, so that the pipette is pulled out of the vessel and guided into the reaction tube 2.
Thereafter, the required amount of the first diluent is dispensed from the pipette into the reaction tube 2 by raising the second cam 9. After this,
When the gripping device 7 stops gripping the pipette, the pipette moves back to the position 1d by means of a spring force, and the diluent dispensing operation described above is completed.
このようにして検体及び４１希釈液１句が分注された反
応管２はピペット装置Ｐの秤取部位まで間歇移送される
。The reaction tube 2 into which the sample and one volume of the 41 diluent have been dispensed in this way is intermittently transferred to the weighing site of the pipette device P.
反応管２が同秤取部位に到来すると、−のクーレット装
置Ｄｚの他のターレット装置Ｄ２との間に配設されたピ
ペット装置Ｐは、間管２内の所定倍率まで希釈された検
体を所要値秤取し、同２０に移し換えられる。When the reaction tube 2 arrives at the same weighing site, the pipette device P disposed between the - coolet device Dz and the other turret device D2 collects the sample diluted to a predetermined ratio in the intervening tube 2. The value is weighed and transferred to 20.
このような作動をするピペット装置Ｐとしでは公知の機
構のものを適用すればよく、要は、反応管２が上記秤取
位置に到来し停止した際に同反応管２内の希釈検体が所
要量秤取でれ、他のターレット装置Ｄ２における反応管
２０に分注されるよう構成されていると共に、次の反応
管２′が同秤取位置に到来するまでの間に洗浄等が行な
われ得るよう構成されていることが必較である。尚、ピ
ペット装置Ｐによる所要量の希釈検体秤取が終了すると
、間管２は、保持装置Ｈ１の回動下流側に配設された洗
浄装置Ｗ１で例えば超音波を利用した洗浄￥段で洗浄さ
れ再使用に供される。As the pipetting device P that operates in this manner, it is sufficient to apply one with a known mechanism.In short, when the reaction tube 2 reaches the above-mentioned weighing position and stops, the diluted sample in the reaction tube 2 is collected as required. It is configured to be weighed and dispensed into the reaction tubes 20 in another turret device D2, and cleaning etc. are performed before the next reaction tube 2' arrives at the same weighing position. It is essential that the system is configured so that it can be obtained. When the required amount of diluted sample is weighed by the pipette device P, the intermediate tube 2 is cleaned by a cleaning stage using ultrasonic waves, for example, by a cleaning device W1 disposed on the rotationally downstream side of the holding device H1. and then provided for reuse.
このようにして所要量の希釈検体が基準位置にで分注さ
れた反応管２０には、この分注作業と同期して同位置に
で第２希釈液Ｒ２が分析項目に対応して分注され、これ
によυ検体の希釈倍率は原液の状態から、例えば１００
０倍程度１で希釈されることとなる。尚、この第２希釈
液Ｒ２の分注は、前述した第１希釈液Ｒノと同様に構成
さｉｌ−だ容器Ｂ２と回答器Ｂ２の後部に配設されたポ
ンプ６′及び把持装置７′によって同様性なわれ、丹た
同容器Ｂ２の上ｎ己基準位置Ｋまでの移送は、これも前
記クーレット装置Ｄｌと同様、制御装置（ＣＰＵ）によ
って駆動制御される駆動装置Ｍ３がターレット状ホルダ
ー１＋−＜回転することで行なわれる。In this way, the required amount of diluted sample is dispensed into the reaction tube 20 at the reference position, and in synchronization with this dispensing operation, the second diluent R2 is dispensed at the same position corresponding to the analysis item. With this, the dilution factor of the υ specimen is, for example, 100% from the undiluted state.
It will be diluted by about 1:0. Note that the dispensing of the second diluent R2 is performed in the same manner as the first diluent R described above, using a pump 6' and a gripping device 7' disposed at the rear of the container B2 and the answering device B2. The transfer of the same container B2 to the upper reference position K is carried out by a drive device M3, which is also driven and controlled by the control device (CPU) like the coolet device Dl. −<It is done by rotating.
このように第２希釈液Ｒ２が分注され、かつ所定希釈倍
率の検体が分注さえしると、同反応管２０は、おｆ拌位
置Ａ寸で数段階（ｎポジ／コン）クイックスキセンして
移送される。つまり反応管２０がｎステップ連続的に移
送されるようｉｉＪ記保持装置［２は、制御装置（ｃｐ
ｕ）の指令により作動する駆動装Ｗ、Ｍ４で駆動制御さ
れている。Once the second diluent R2 has been dispensed and the sample at a predetermined dilution ratio has been dispensed, the reaction tube 20 is moved to several stages (n positive/con) at the f stirring position A dimension. and transported. In other words, the holding device [2 is a control device (cp
The drive is controlled by drive units W and M4 which operate according to the command of u).
同撹拌位ｉｆ￥Ａ′ｔ′は、反応管２Ｕ内の希釈検体は
、例えば超音波振動４ｆｔ拌装置等の公知撹拌装置１１
に」：り十分な撹拌処理が行なわれ、ｊ′Ｊｖ、拌か終
了すると、同反応管２０は前記基準位置によシ１ポジシ
ョン進んだ位置、すなわち、保持装置Ｈ２に保持された
反応管２０の各間歇停止位置が一周Ｎ箇所設定されてい
るとした場合、
Ｎ−（ｎ−１）
に名画する位置（以下、エンドポジションＥという。）
まで低速スキャン移送されるよう駆動制御され、同スキ
ャン作動中に光学測定装置１２による比色測定が行なわ
れて該データは制御装置（ｃｐｔｇに入力される。The stirring position if\A't' is such that the diluted sample in the reaction tube 2U is mixed with a known stirring device 11, such as an ultrasonic vibration 4ft stirring device.
When sufficient stirring is performed and the stirring is completed, the reaction tube 20 moves to a position one position further from the reference position, that is, the reaction tube 20 held by the holding device H2. Assuming that each intermittent stop position is set at N positions in one round, the position to be stopped at N-(n-1) (hereinafter referred to as end position E).
During the scanning operation, colorimetric measurement is performed by the optical measurement device 12, and the data is input to the control device (CPTG).
このように基準位置Ｋから攪拌位置Ａまで、及び攪拌位
ｔｉｉＡからエンドポジション位ｔＥ−ｉで反応管２０
をスキャン移送するのは、免疫分析において検体に第２
希釈液Ｒ２が分注された後は、これらをできる限り素早
く攪拌し、粒子の均一化を図シ凝集反応を均一ならしめ
た上で測定しなければならないという免疫分析掌上の絶
対的要請に答える必要があるからである。In this way, the reaction tube 20 is moved from the reference position K to the stirring position A, and from the stirring position tiiA to the end position tE-i.
Scanning and transporting the sample is the second step in immunoassay.
After the diluent R2 has been dispensed, it must be stirred as quickly as possible to homogenize the particles and the agglutination reaction must be uniform before measurement, which is an absolute requirement for immunoassays. This is because it is necessary.
尚、同反応管２０を前記基準位置Ａまでスキャン移送す
るのではなく、同位置Ａより１ポジシヨン進んだエンド
ポジションＥまで移送するよう制御したのは、エンドポ
ジションＥで反応管２０が停止したときに同反応管２０
のすぐ下流側の反応管２０′は基準位置Ｋに位置するこ
とから、同前２０′には、前記ターレット装置Ｄ１の対
応反応管２１内の検体が前述と同様の手順で分注される
こととなるので１のターレット装置Ｄ１に保持された各
反応管２内の検体が順次連続して所要複数回、光学測定
されるよう配慮したからである。The reaction tube 20 was not scanned and transferred to the reference position A, but was controlled to be transferred to the end position E, which is one position ahead of the same position A, when the reaction tube 20 stopped at the end position E. 20 reaction tubes
Since the reaction tube 20' immediately downstream of is located at the reference position K, the sample in the corresponding reaction tube 21 of the turret device D1 is dispensed into the same 20' in the same manner as described above. Therefore, consideration was given so that the specimens in each reaction tube 2 held in one turret device D1 would be optically measured a plurality of times in sequence.
このようにしてスキャン移送された反応管２０は、所要
時間経過後に洗浄装置Ｗ２まで移送され、同装置Ｗ２で
例えば超音波洗浄手段によって排水、洗浄作業が行なわ
れることで再び利用可能状態にリセットされる。The reaction tube 20 scanned and transferred in this manner is transferred to the cleaning device W2 after the required time has elapsed, and is reset to a usable state again by being drained and cleaned by ultrasonic cleaning means in the same device W2. Ru.
この発明に係る自動分析装置は、以上説明したように、
ｌのターレット装置Ｄｌと他のターレット装置Ｄ２の夫
々において、測定項目に対応する希釈作業を分担させて
行うように構成し、同他のターレット装置Ｄ２では、■
のターレット装置ＤＩで所定希釈倍率まで希釈された検
体を所要量秤取してこれに第２希釈液Ｒ２を注入するよ
うに構成されているので、第１希釈液Ｒ１が注入された
ままの状態で第２希釈液を加えるのとは異なり第２希釈
液Ｒ２の消費量を大幅に削減することができるとともに
、同希釈作業を容易かつ高精度に行うことができ、更に
は装置全体’ｔ ／Ｊ−型化することもできる。As explained above, the automatic analyzer according to the present invention has the following features:
The turret device Dl and the other turret device D2 are configured to share the dilution work corresponding to the measurement item, and the other turret device D2 performs the dilution work corresponding to the measurement item.
The turret device DI is configured to weigh the required amount of the sample diluted to a predetermined dilution ratio and inject the second diluent R2 into it, so the first diluent R1 remains injected. Unlike adding the second diluent R2, the consumption amount of the second diluent R2 can be significantly reduced, and the dilution work can be performed easily and with high precision. It can also be made into a J-type.
またこの発明にあっては、第２希釈液Ｒ２が注入された
後は、瞬時にこれを攪拌するように構成したので、凝集
反応を均一化せしめることｉｘでき測定データに対する
信頼性が大幅に向上する。Furthermore, in this invention, after the second diluent R2 is injected, it is instantaneously stirred, so that the aggregation reaction can be made uniform, and the reliability of the measurement data can be greatly improved. do.
図面ｔ；Ｌこの発明の一実施例に係る自動分析装置の構
成を概略的に示す説明図である。
Ｂｌ、Ｂ２・・・容器 ＣＰＵ・・・制御装置Ｄ１．Ｄ
２・・・ターレット装置
Ｈｌ 、Ｈｚ・・・保持装置
Ｍｌｌ Ｍ２． Ｍ３． Ｍ４・・・駆動装置Ｐ・・・
ピペット装置 Ｒ１・・・第１希釈液Ｒ２・・・第２希
釈液
ｌ、１′・・・ターレット状ホルダー
２．２０・・・反応管 ４・・・ザンプラ−１１・・・
攪拌装置 １２・・・ブ［♀測定装置特肝出細入 日本
テクトロン株式会社Drawing t;L is an explanatory diagram schematically showing the configuration of an automatic analyzer according to an embodiment of the present invention. Bl, B2... Container CPU... Control device D1. D
2...Turret device Hl, Hz...Holding device Mll M2. M3. M4...Drive device P...
Pipette device R1...First diluent R2...Second diluent l, 1'...Turret-shaped holder 2.20...Reaction tube 4...Sampler 11...
Stirring device 12...B [♀ Measuring device special liver outlet Nippon Techtron Co., Ltd.
Claims (1)
器全ターレット状ホルダーに放射状に保持し、該ホルダ
ーは所望希釈液を対応反応管に所定位置で注入し得るよ
う駆動装置で移送制御されており、かつ同ホルダーの外
周に配設されたターレント状の保持装置には、上記反応
管が複数本所要間隔毎に保持さｎ１同装置は駆動装置で
所定回動されるよう駆動制御されてなるターレット装置
を所要間隔離間させて一対並設し、一方のターレット装
置における反応管には、検体秤取分注装置でザンプラー
内よυ秤取された検体が所定位置で注入され、この後同
反応管には分析項目に対応する希釈液が所要量注入され
所定希釈倍率に希釈された後ピペット装置の秤取部位ま
で移送されるように駆動制御されていると共に、他のタ
ーレット装置における反応管は、ピペット装置で所要量
秤取された所定希釈倍率の検体が所要量分注された後、
分析項目に対応して更に第２のターレット装置における
希釈液が所要量注入されることで所望希釈倍率まで希釈
され、この後同反応管は攪拌位置まで回動制御され、同
位置で所定攪拌が行なわれた後、前記保持装置は同反応
管を上記ピペット装置による所定希釈倍率の検体注入位
置より一ポジション進んだ間歇移動位置までスキャン作
動するよう回動制御され、同スキャン作動中に検体の比
色測定を光学装置で行なうよう構成されでなる自動分析
装置。A plurality of valley vessels containing the diluent required for the required analysis item are held radially in a turret-like holder, and the holder is transported by a drive device so that the desired diluted solution can be injected into the corresponding reaction tube at a predetermined position. A plurality of reaction tubes are held at required intervals in a tartent-shaped holding device arranged on the outer periphery of the holder, and the device is driven and controlled by a drive device so that it can be rotated in a predetermined manner. A pair of turret devices are arranged in parallel with a required distance between them, and a sample weighed from the sampler by the sample weighing and dispensing device is injected into the reaction tube of one of the turret devices at a predetermined position. After that, the reaction tube is driven and controlled so that the required amount of diluent corresponding to the analysis item is injected, diluted to a predetermined dilution ratio, and then transferred to the weighing part of the pipette device. After the required amount of sample at a predetermined dilution rate is dispensed into the reaction tube using a pipette device,
The required amount of diluent is further injected into the second turret device according to the analysis item, thereby diluting it to the desired dilution ratio. After that, the reaction tube is controlled to rotate to the stirring position, and a predetermined stirring is performed at the same position. After that, the holding device is rotationally controlled to scan the reaction tube to an intermittent movement position that is one position ahead of the position where the pipette injects the sample at a predetermined dilution ratio. An automatic analyzer configured to measure color using an optical device.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11244283A JPS604861A (en) | 1983-06-22 | 1983-06-22 | Automatic analytical apparatus |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11244283A JPS604861A (en) | 1983-06-22 | 1983-06-22 | Automatic analytical apparatus |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS604861A true JPS604861A (en) | 1985-01-11 |
| JPH0472186B2 JPH0472186B2 (en) | 1992-11-17 |
Family
ID=14586728
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP11244283A Granted JPS604861A (en) | 1983-06-22 | 1983-06-22 | Automatic analytical apparatus |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS604861A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4699766A (en) * | 1985-05-30 | 1987-10-13 | Kabushiki Kaisha Toshiba | Automatic chemical analyzer |
| JPH0255957A (en) * | 1988-08-22 | 1990-02-26 | Nittec Co Ltd | Automatic analyzer |
| JPH0534976U (en) * | 1991-09-10 | 1993-05-14 | 株式会社丸八真綿 | pillow |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5322495A (en) * | 1976-08-13 | 1978-03-01 | Shimadzu Corp | Automatic analyzer |
| JPS5589753A (en) * | 1978-12-28 | 1980-07-07 | Nippon Kogaku Kk <Nikon> | Intermittent carrier |
| JPS5598360A (en) * | 1979-01-22 | 1980-07-26 | Dai Ichi Seiyaku Co Ltd | Automation method of chemical agent test |
| JPS5631358U (en) * | 1979-08-17 | 1981-03-26 | ||
| JPS56140257A (en) * | 1980-04-04 | 1981-11-02 | Hitachi Ltd | Automatic analyzer |
| JPS56168554A (en) * | 1980-05-30 | 1981-12-24 | Hitachi Ltd | Automatic analyzer |
| JPS5885168A (en) * | 1981-11-16 | 1983-05-21 | Toshiba Corp | Automatic chemical analyzer |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5183845A (en) * | 1975-01-20 | 1976-07-22 | Citizen Watch Co Ltd | TOKEIGAISOBUHIN |
-
1983
- 1983-06-22 JP JP11244283A patent/JPS604861A/en active Granted
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5322495A (en) * | 1976-08-13 | 1978-03-01 | Shimadzu Corp | Automatic analyzer |
| JPS5589753A (en) * | 1978-12-28 | 1980-07-07 | Nippon Kogaku Kk <Nikon> | Intermittent carrier |
| JPS5598360A (en) * | 1979-01-22 | 1980-07-26 | Dai Ichi Seiyaku Co Ltd | Automation method of chemical agent test |
| JPS5631358U (en) * | 1979-08-17 | 1981-03-26 | ||
| JPS56140257A (en) * | 1980-04-04 | 1981-11-02 | Hitachi Ltd | Automatic analyzer |
| JPS56168554A (en) * | 1980-05-30 | 1981-12-24 | Hitachi Ltd | Automatic analyzer |
| JPS5885168A (en) * | 1981-11-16 | 1983-05-21 | Toshiba Corp | Automatic chemical analyzer |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4699766A (en) * | 1985-05-30 | 1987-10-13 | Kabushiki Kaisha Toshiba | Automatic chemical analyzer |
| JPH0255957A (en) * | 1988-08-22 | 1990-02-26 | Nittec Co Ltd | Automatic analyzer |
| JPH0534976U (en) * | 1991-09-10 | 1993-05-14 | 株式会社丸八真綿 | pillow |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0472186B2 (en) | 1992-11-17 |
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