JPS59130528A - Chemical manipulator - Google Patents
Chemical manipulatorInfo
- Publication number
- JPS59130528A JPS59130528A JP459483A JP459483A JPS59130528A JP S59130528 A JPS59130528 A JP S59130528A JP 459483 A JP459483 A JP 459483A JP 459483 A JP459483 A JP 459483A JP S59130528 A JPS59130528 A JP S59130528A
- Authority
- JP
- Japan
- Prior art keywords
- mixer
- centrifugal separator
- constant temperature
- reaction vessel
- rotary table
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J4/00—Feed or outlet devices; Feed or outlet control devices
- B01J4/008—Feed or outlet control devices
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
Abstract
Description
【発明の詳細な説明】
この発明は、ケミカルマニピュレータに関し、特に、μ
を単位の液体の解析及び分析工程を自動化するための新
規な改良に関するものである。DETAILED DESCRIPTION OF THE INVENTION The present invention relates to a chemical manipulator, and in particular to a μ
The present invention relates to novel improvements for the analysis of unit liquids and for automating analytical processes.
従来、用いら扛ていたμｔオーダーの液体等の解析工程
は、極めて複雑なものであり、その大部分全研究者の手
作業によって行なっていた。The process of analyzing liquids, etc. on the μt order, which has not been used in the past, is extremely complicated, and most of it is performed manually by all researchers.
この発明は、以上の欠点をすみやかに除去するための極
めて効果的な手段を提供することを目的とするもので、
特に、回転自在に設けらｎ反応容器をもつ回転テーブル
を備えた遠心分離装置と、試薬吐出ノズル、乾燥用吸引
ノズルおよび反応容器用蓋脱着装置金有し上下動自在に
設けらｎたノズル上下装置と、恒温槽おこびミキサとを
有し上下動自在に設けらｎ７′ｃ恒温槽及びミキサ上下
装置とを有し、遠心分離装置に対してノズル上下装置お
よび恒温槽及びミキサ上下装Ｒを上下動させるようにし
た構成である。The purpose of this invention is to provide extremely effective means for quickly eliminating the above-mentioned drawbacks.
In particular, a centrifugal separator equipped with a rotary table having a rotatably mounted reaction vessel, a reagent discharging nozzle, a drying suction nozzle, and a lid removal device for the reaction vessel are provided, and the nozzle is movable up and down. It has a constant temperature chamber and a mixer up/down device, and is equipped with a nozzle up/down device, a constant temperature bath, and a mixer up/down device R for the centrifugal separator. It is configured to move up and down.
以下、図面と共にこの発明によるケミカルマニピュレー
タの好適な一実施例について詳細に説明する。Hereinafter, a preferred embodiment of the chemical manipulator according to the present invention will be described in detail with reference to the drawings.
図面において、符号１で示さしるものは遠心分離装置で
あり、この遠心分離装置１の駆動軸２には、複数の反応
容器３をその周端部に有する回転テーブル４が回転可能
に装着さｎている。前記駆動軸２のほぼ中央部には検出
円板５が設けらｎｌこの検出円板５の一端は、全体がコ
字型をなす回転位置出しセンサ６と重合するように配設
さｊしており、回転テーブル４の回転位置を検出するこ
とができる。In the drawings, the reference numeral 1 indicates a centrifugal separator, and a rotary table 4 having a plurality of reaction vessels 3 at its peripheral end is rotatably attached to a drive shaft 2 of the centrifugal separator 1. There are n. A detection disk 5 is provided approximately at the center of the drive shaft 2, and one end of the detection disk 5 is arranged so as to overlap with a rotational positioning sensor 6 having a U-shape as a whole. Therefore, the rotational position of the rotary table 4 can be detected.
前記遠心分離装置１の上部位置には、試薬吐出ノズル７
、乾燥用吸引ノズル８および反応容器用蓋脱着装置間と
を有する保持板９を有するノズル上下装置１０が配設さ
ｎており、この保持板９は一体に設けらｆた軸１１が矢
印Ａの方向に上下動する構成である。A reagent discharge nozzle 7 is located at the upper part of the centrifugal separator 1.
, a nozzle up/down device 10 having a holding plate 9 having a drying suction nozzle 8 and a reaction vessel lid attachment/detachment device is disposed, and this holding plate 9 is integrally provided with a shaft 11 pointing in the direction of arrow A. It is configured to move up and down in the direction of.
又、この反応容器用蓋脱着装置３０には、電磁ソレノイ
ド３１と３２の間に付着部３３が入るように上下動可能
なプランジャ４３が配設さｎ１反応容器３の蓋３６の爪
４０を引掛けるピックアップ部３７を有する上下動可能
な内筒３４が配設さｎて外筒３８により支持さ扛ている
。さらに反応容器用蓋脱着装置３０はその上部に配設さ
ｎた回転駆動モータ３９にエフ回転運動ができるように
構成さｒている。尚、内筒３４の寸法（イ）は蓋３６の
寸法ｅｅよりも小さく寸法（ロ）よＶも大きく構成さｎ
ており、さらに内筒３４の寸法に）は蓋３６の寸法（ハ
）よジも大きく構成さ几ており、外筒３８の底部３５も
内筒３４の底部と同様形状を表している。Further, this reaction vessel lid attachment/detachment device 30 is provided with a plunger 43 that can move up and down so that the attachment part 33 is inserted between the electromagnetic solenoids 31 and 32. A vertically movable inner cylinder 34 having a pick-up part 37 to hang thereon is disposed and supported by an outer cylinder 38. Further, the reaction container lid attachment/detachment device 30 is configured so that a rotary drive motor 39 disposed above it can perform rotational movement. Note that the dimension (a) of the inner cylinder 34 is smaller than the dimension ee of the lid 36, and the dimension (b) and V are also larger.
In addition, the dimensions of the inner cylinder 34 () and the dimensions (c) of the lid 36 are also large, and the bottom 35 of the outer cylinder 38 has the same shape as the bottom of the inner cylinder 34.
さらに、前記遠心分離装置１の下部位置には、恒温槽１
４およびミギサ１５とをその周端部に有する保持板１Ｇ
を備えた恒温槽及びミキサ上下装置１７が配設さｎｌこ
の保持板１６に一体に設けら、ｆ′Ｌ、 ｆｃ軸１８が
、電磁プランジャ１９ヲ有する保持筒体２０内に矢印Ｂ
の方向において上下動自在に設けら牡ていると共に、前
記電磁プランジャ１９ヲ作動させることにより、保持板
１６が矢印Ｂの方向にシいて上下動できる構成である。Further, a constant temperature bath 1 is provided at the lower part of the centrifugal separator 1.
4 and a retainer plate 1G having a migisa 15 at its peripheral end.
A constant temperature chamber and a mixer up/down device 17 equipped with the above are provided integrally with this holding plate 16, and the f'L and fc shafts 18 are arranged in the direction of arrow B in the holding cylinder 20 having an electromagnetic plunger 19.
By operating the electromagnetic plunger 19, the holding plate 16 can be moved up and down in the direction of arrow B.
尚、駆動軸２、軸１１および１８は、同一中心線上に位
置している。Note that the drive shaft 2 and the shafts 11 and 18 are located on the same center line.
前記試薬吐出ノズル７には、試薬送液装置２１から送ら
ｎた試薬がμｔのオーダーで吐出され、前記乾燥用吸引
ノズル８は、冷却装置２２に接続さｎたコンデンサｎが
接続さｎると共に、このコンデンサおの出力は真空ポン
プ属に接続さ粁ている。The reagent sent from the reagent liquid feeding device 21 is discharged to the reagent discharge nozzle 7 on the order of μt, and the drying suction nozzle 8 is connected to a condenser connected to the cooling device 22. , the output of this capacitor is connected to the vacuum pump.
前記恒温槽１４は、温度制御装置５に接続さｎて一定温
度に制御さｎており、シーケンスコントローラ２６から
の出力制御信号は、前記真空ポンプ２４、遠心分離装置
１０回転駆動モータ１ｃＬ１恒温槽及びミキサ上下装置
１７の電磁プランジャ１９、試薬送液装置２１、ノズル
上下装置１０の電磁プランジャ１３および反応容器用蓋
脱着装置の回転駆動モータ３９、電磁ソレノイド３１
、３２に供給さ几て、各々を制御している。The constant temperature bath 14 is connected to the temperature control device 5 and controlled to a constant temperature, and the output control signal from the sequence controller 26 is transmitted to the vacuum pump 24, the centrifugal separator 10 rotation drive motor 1cL1 constant temperature bath and The electromagnetic plunger 19 of the mixer up/down device 17, the reagent liquid feeding device 21, the electromagnetic plunger 13 of the nozzle up/down device 10, the rotational drive motor 39 of the reaction vessel lid removal device, and the electromagnetic solenoid 31
, 32 and control each of them.
上記のような構成において、この発明によるケミカルマ
ニピュレータを作動させる場合について述べると、試薬
送液装置２１から送らｎた試薬は電磁プランジャ１３が
作動して保持板９が降下し、試薬吐出ノズル７が反応容
器３に接合した状態で、反応容器３内にμを単位で注入
さｎる。さらに、回転テーブル４に設けらｎた他の反応
容器３に試薬を注入する場合には、シーケンスコントロ
ーラ２６からの制御信号によシ回転駆動モータ１αを所
定角度回転させて、他の反応容器３を試薬吐出ノズル７
に対応した位置迄回転移動させる。この状態で再び電磁
プランジャ１３を作動させると、保持板９が降下し、前
述と同様の動作により試薬吐出ノズル７から反応容器３
にμを単位の試薬が注入さ肚る。In the above configuration, when the chemical manipulator according to the present invention is operated, the reagent sent from the reagent feeding device 21 is actuated by the electromagnetic plunger 13, the holding plate 9 is lowered, and the reagent discharge nozzle 7 is moved. While connected to the reaction vessel 3, μ is injected into the reaction vessel 3 in units of n. Further, when injecting a reagent into another reaction container 3 provided on the rotary table 4, the rotation drive motor 1α is rotated by a predetermined angle according to a control signal from the sequence controller 26, and the other reaction container 3 is injected. Reagent discharge nozzle 7
Rotate and move to the corresponding position. When the electromagnetic plunger 13 is operated again in this state, the holding plate 9 is lowered, and the reagent discharge nozzle 7 is moved from the reaction vessel 3 by the same operation as described above.
Allow μ units of reagent to be injected.
さらに、前記反応容器３内の水分を除去する場合には、
回転駆動モータ１αを作動させて回転テーブル４を回転
させ、反応容器３を乾燥用吸引ノズル８に対応した位置
に位置させ電磁プランジャ１３を作動させると、保持板
９が降下して乾燥用吸引ノズル８が反応容器３に密着し
、遠心分離後の反応容器３内の液体は真空ポンプ冴とコ
ンデンサ乙により吸引さ几る。Furthermore, when removing moisture in the reaction vessel 3,
When the rotary drive motor 1α is operated to rotate the rotary table 4, the reaction container 3 is positioned at a position corresponding to the drying suction nozzle 8, and the electromagnetic plunger 13 is activated, the holding plate 9 is lowered and the drying suction nozzle is opened. 8 is in close contact with the reaction vessel 3, and the liquid in the reaction vessel 3 after centrifugation is sucked out by the vacuum pump A and the condenser B.
又、反応容器３内の試料の温度を急激に上下させる場合
には、電磁プランジャ１９ヲ作動させて保持板１６を上
昇させると、恒温槽１４が上昇して反応容器３が恒温槽
１４内に入った状態となり、恒温槽１４に設定さ、ｆ′
した温度に前記反応容器３内の温度が一定時間内に変更
さｎる。In addition, when the temperature of the sample in the reaction container 3 is to be rapidly raised or lowered, the electromagnetic plunger 19 is operated to raise the holding plate 16, and the thermostatic chamber 14 is raised, causing the reaction container 3 to be placed inside the thermostatic chamber 14. The temperature is set in the constant temperature bath 14, and f'
The temperature inside the reaction vessel 3 is changed to the same temperature within a certain period of time.
さらに、ｍＩ記反応容器３の蓋３６を反応容器３に取付
ける場合は、回転駆動モータ１αを作動させて回転テー
ブル４ｆ：回転させ、反応容器３を反応容器用蓋脱着装
置３０に対応した位置に位置させ電磁プランジャ１３を
作動させると、保持板９が降下して第２図（Ａ）に示す
状態となり、この状態で電磁ソ１／ノイド３２ヲ作動さ
せるとプランジャ４３の付着部３３が電磁ソレノイド３
２に吸引さｎてプランジャ４３が降下して第２図中）の
状態となり、プランジャ４３の押付部４２降下して蓋３
６ヲ押付は反応容器３に蓋３６が押付取付けらｎる。取
付後、回転駆動モータ３９により反応容器側蓋脱装装置
３０全所定角度回転させると、内筒あのピックアップ部
３７および外筒３８の底部３５が蓋３６の爪４０を引掛
ける位置から外扛、第２図（０）に示す状態となり、こ
の状態で電磁プランジャ１３ヲ作動させると保持板９が
上昇して反応容器用蓋脱着装置３０が蓋３６から離ｎ蓋
３６が取付けら２″した反応容器３が回転テーブル４に
残る。又、この状態から再び反応容器３から蓋３６を取
り外す場合には、以上の工程の逆を行うことにより第２
図（０）の状態から第２図（Ｂ）の状態にして、電磁ソ
レノイド３１を作動させることによってプランジャ４３
を上昇させ、この時押付部４２が内筒３４ヲ押し上げて
ピックアップ部３７が蓋３６の爪４０を引掛けて反応容
器３より蓋３６を取外す。Furthermore, when attaching the lid 36 of the reaction vessel 3 to the reaction vessel 3, the rotary drive motor 1α is operated to rotate the rotary table 4f, and the reaction vessel 3 is placed in a position corresponding to the reaction vessel lid attachment/detachment device 30. When the electromagnetic plunger 13 is positioned and operated, the holding plate 9 descends to the state shown in FIG. 3
2, the plunger 43 descends to the state shown in FIG.
Pressing 6 presses and attaches the lid 36 to the reaction vessel 3. After installation, when the reaction vessel side lid removal device 30 is entirely rotated by a predetermined angle by the rotary drive motor 39, the pick-up portion 37 of the inner cylinder and the bottom 35 of the outer cylinder 38 will be removed from the position where the claws 40 of the lid 36 are hooked. The state shown in FIG. 2 (0) is reached, and when the electromagnetic plunger 13 is operated in this state, the holding plate 9 is raised and the reaction vessel lid attachment/detachment device 30 is separated from the lid 36. The container 3 remains on the rotary table 4.In addition, when removing the lid 36 from the reaction container 3 again from this state, the second step is performed by reversing the above steps.
By changing the state shown in FIG. 2(B) from the state shown in FIG.
At this time, the pressing part 42 pushes up the inner cylinder 34 and the pickup part 37 hooks the claw 40 of the lid 36 to remove the lid 36 from the reaction vessel 3.
この時、外筒３８の底部３５は、反応容器３がｉ３６と
共に上昇しないように反応容器３を押付ける作用をなす
。At this time, the bottom portion 35 of the outer cylinder 38 acts to press the reaction container 3 so that the reaction container 3 does not rise together with the i36.
従って本実施例によｎば反応容器３内の試料の遠心分離
、試薬注入、乾燥、温度変化およびミキシング等の動作
を全く人手を介することなくシーケンスコントローラに
より極めて簡単、正確に、かつ、自動的に行なうことが
できるものであり、従来、多くの研究者により行なわし
てきた困難な作業を迅速に行なうことができるようにな
った効果は、極めて有益なことである。Therefore, according to this embodiment, operations such as centrifugation of the sample in the reaction container 3, reagent injection, drying, temperature change, and mixing can be performed extremely easily, accurately, and automatically by the sequence controller without any manual intervention. The effect of this is that it is now possible to quickly perform difficult tasks that have traditionally been performed by many researchers, which is extremely beneficial.
特に反応容器の蓋を自動的に脱着できるように横取した
ことは、遠心分離、ミキシング等に於ける反応容器内の
液体の飛散を防止できると共に自然蒸発を防止すること
ができ、尚かつ試薬の注入も自在に行うことができると
いう絶大な効果をもたらすものである。In particular, the lid of the reaction container can be automatically attached and removed, which prevents the liquid in the reaction container from scattering during centrifugation, mixing, etc., and also prevents natural evaporation. It has the tremendous effect of being able to freely perform injections.
第１図は、この発明によるシーケンサ装置Ｉｆ’に示す
全体′Ｊ：ｆｔ成図、第２図（Ａ） 、 （Ｂ） 、
（０）は要部を示す断面側面図、第２図ＣＤ）は第２図
（０）に於いて矢視了−アによる断面図、第３図（ハ）
）、伊）は要部を示す見取ジ図である。
１、。遠心分離装置 ３０１反応容器４、。回転テー
ブル （９）０１反反応容器３内％ｆ Ｍ ３６
、 、 蓋４３ 、 、プランジャである。
以上
出願人 株式会社第二精玉舎
代理人 弁理士最上 務
第２図（△） 第２図ＣＢ）
第２図（Ｃ）
第３図（Ａ）
第３図（Ｂ）FIG. 1 shows the entire 'J:ft diagram of the sequencer device If' according to the present invention, and FIG. 2 (A), (B),
(0) is a cross-sectional side view showing the main parts, Figure 2 (CD) is a cross-sectional view taken along arrows R - A in Figure 2 (0), Figure 3 (C)
), Italy) are sketches showing the main parts. 1. Centrifugal separator 301 reaction vessel 4. Rotary table (9) 01 Reaction vessel 3 %f M 36
, , lid 43 , , a plunger. Applicant Daini Seidokusha Co., Ltd. Agent Patent Attorney Mogami Figure 2 (△) Figure 2 CB) Figure 2 (C) Figure 3 (A) Figure 3 (B)
Claims (1)
ルを有する遠心分離装置と、この回転テーブルの回転位
置を検出するための回転位置出し検出部と、前記遠心分
離装置の上記位置に設けらｎ試薬吐出ノズル、乾燥用吸
引ノズルおよび前記反応容器用蓋脱着装置とを有する保
持体と、前記遠心分離装置の下部位置に設けらｎ恒温お
よびミキサーとを有すると共にその支軸ガロに移動自在
に設けらｔｙｃ恒温及びミキサー上下装置と、前記試薬
吐出ノズル、乾燥用吸引ノズル、遠心分離装置、恒温槽
反応容器用量脱着装置およびミキサー上下装置の作動全
制御するためのシーケンスコントローラとを備え、前記
反応容器内の液体の飛散又は蒸発を防ぐために前記反応
容器用蓋脱着装置により必要の都度自動的に蓋を脱着さ
せるように構成したことを特徴とするケミカルマニピュ
レータ。A centrifugal separator having a plurality of reaction vessels and a rotary table provided rotatably; a rotation position detecting section for detecting the rotational position of the rotary table; A holder having a reagent discharge nozzle, a drying suction nozzle, and the reaction container lid attachment/detachment device, and a constant temperature and mixer provided at a lower position of the centrifugal separator, and is movable on its spindle. tyc constant temperature and mixer up/down device, and a sequence controller for fully controlling the operations of the reagent discharge nozzle, drying suction nozzle, centrifugal separator, constant temperature bath reaction vessel dosage/desorption device, and mixer up/down device, 1. A chemical manipulator, characterized in that the reaction container lid removal device automatically attaches and detaches the lid whenever necessary in order to prevent the liquid in the reaction container from scattering or evaporating.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP459483A JPS59130528A (en) | 1983-01-14 | 1983-01-14 | Chemical manipulator |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP459483A JPS59130528A (en) | 1983-01-14 | 1983-01-14 | Chemical manipulator |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS59130528A true JPS59130528A (en) | 1984-07-27 |
Family
ID=11588365
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP459483A Pending JPS59130528A (en) | 1983-01-14 | 1983-01-14 | Chemical manipulator |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS59130528A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107537432A (en) * | 2017-10-23 | 2018-01-05 | 陕西路盾公路工程有限公司 | A kind of reaction kettle device that can quickly open maintenance for Chemical Manufacture |
| CN108709792A (en) * | 2018-07-06 | 2018-10-26 | 山东华盛天同标准技术服务有限公司 | A kind of detection food heavy metal heating resolution automatic control device |
| WO2020189395A1 (en) * | 2019-03-19 | 2020-09-24 | パナソニックＩｐマネジメント株式会社 | Dispensing method and dispensing device |
-
1983
- 1983-01-14 JP JP459483A patent/JPS59130528A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107537432A (en) * | 2017-10-23 | 2018-01-05 | 陕西路盾公路工程有限公司 | A kind of reaction kettle device that can quickly open maintenance for Chemical Manufacture |
| CN108709792A (en) * | 2018-07-06 | 2018-10-26 | 山东华盛天同标准技术服务有限公司 | A kind of detection food heavy metal heating resolution automatic control device |
| CN108709792B (en) * | 2018-07-06 | 2023-09-12 | 方圆标志检验检测(山东)有限公司 | Automatic control device is cleared up in heating of detection food heavy metal |
| WO2020189395A1 (en) * | 2019-03-19 | 2020-09-24 | パナソニックＩｐマネジメント株式会社 | Dispensing method and dispensing device |
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