JPS5798215A - Novel m5071-like substance - Google Patents
Novel m5071-like substanceInfo
- Publication number
- JPS5798215A JPS5798215A JP55174853A JP17485380A JPS5798215A JP S5798215 A JPS5798215 A JP S5798215A JP 55174853 A JP55174853 A JP 55174853A JP 17485380 A JP17485380 A JP 17485380A JP S5798215 A JPS5798215 A JP S5798215A
- Authority
- JP
- Japan
- Prior art keywords
- substance
- gnomoniella
- recovered
- stable
- reactions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
Abstract
NEW MATERIAL:M5071 substance-like M5093 substance. Molecular weight: about 59,000; isoelectric point: near pH3.1; solubility: easy soluble in water, insoluble in methanol, acetone or chloroform; color reactions; positive to biuret, xanthoproteic and Folin's reactions; color: white; pH stability: stable at 4W8pH; thermal stability: stable up to 60°C, 100% deactivated at 80°C.
USE: It inhibits the formation of insoluble glucan by glucosyl transferrase and is used to prevent tooth decay.
PREPARATION: A strain in Gnomoniella, capable of producing M5071 substance- like M5093 substance, such as Gnomoniella s.p. M5093 (FERM-5799) is subjected to usual liquid cultivation and the objective substance is recovered from the culture medium filtrate by salting-out or adsorption chromatography. Further, the active fraction is recovered by the isoelectric electrophoresis and the resultant M5093 substance is freeze-dried.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55174853A JPS5798215A (en) | 1980-12-10 | 1980-12-10 | Novel m5071-like substance |
GB8101377A GB2069499B (en) | 1980-01-18 | 1981-01-16 | Proteins which inhibit glucosyltransferase for use in prevention of dental caries |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55174853A JPS5798215A (en) | 1980-12-10 | 1980-12-10 | Novel m5071-like substance |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5798215A true JPS5798215A (en) | 1982-06-18 |
JPS6342634B2 JPS6342634B2 (en) | 1988-08-24 |
Family
ID=15985788
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP55174853A Granted JPS5798215A (en) | 1980-01-18 | 1980-12-10 | Novel m5071-like substance |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5798215A (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH04217531A (en) * | 1990-12-14 | 1992-08-07 | Alps Electric Co Ltd | Feeder cassette |
-
1980
- 1980-12-10 JP JP55174853A patent/JPS5798215A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS6342634B2 (en) | 1988-08-24 |
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