JPS5775953A - Novel derivative of 2-hydroxyoxanilic acid - Google Patents

Novel derivative of 2-hydroxyoxanilic acid

Info

Publication number
JPS5775953A
JPS5775953A JP55151816A JP15181680A JPS5775953A JP S5775953 A JPS5775953 A JP S5775953A JP 55151816 A JP55151816 A JP 55151816A JP 15181680 A JP15181680 A JP 15181680A JP S5775953 A JPS5775953 A JP S5775953A
Authority
JP
Japan
Prior art keywords
compound shown
formula
formulai
cyano
halogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP55151816A
Other languages
Japanese (ja)
Inventor
Kiyoshi Murase
Toshiyasu Mase
Kenichi Tomioka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamanouchi Pharmaceutical Co Ltd
Original Assignee
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Pharmaceutical Co Ltd filed Critical Yamanouchi Pharmaceutical Co Ltd
Priority to JP55151816A priority Critical patent/JPS5775953A/en
Priority to CA000365668A priority patent/CA1181070A/en
Priority to ES80497294A priority patent/ES8201955A1/en
Priority to AT80304303T priority patent/ATE7385T1/en
Priority to EP80304303A priority patent/EP0030436B1/en
Priority to DE8080304303T priority patent/DE3067784D1/en
Publication of JPS5775953A publication Critical patent/JPS5775953A/en
Priority to US06/416,317 priority patent/US4457872A/en
Pending legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

NEW MATERIAL:A compound shown by the formulaI(A is OH or lower alkoxy; amino, etc.; R1 is cyano, carboxy, etc. R2 is H or halogen; with the proviso that R1 is linked to 4- or 5- position) and its slat.
EXAMPLE: Ethyl 5-cyano-2-hydroxyoxanilate.
USE: An antiallergic. An antiashmatic. An antirheumatic. A carcinostatic agent. Useful as a remedy for an autoimmune disease and an inhibitor for rejection reactions in organ implantation and skin implantation. Having immune factor regulating action.
PROCESS: A compound shown by the formula II (Z is H or OH-protecting group) is reduced to give a compound shown by the formula III, which is reacted with an oxanilic acid shown by the formula IV (X is OH, halogen) or its reactive derivative to give a compound shown by the formula V. If necessary, the protecting group is removed to tive a compound shown by the formulaI.
COPYRIGHT: (C)1982,JPO&Japio
JP55151816A 1979-11-28 1980-10-29 Novel derivative of 2-hydroxyoxanilic acid Pending JPS5775953A (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
JP55151816A JPS5775953A (en) 1980-10-29 1980-10-29 Novel derivative of 2-hydroxyoxanilic acid
CA000365668A CA1181070A (en) 1979-11-28 1980-11-27 Process of producing 2-hydroxyoxanilic acid derivatives
ES80497294A ES8201955A1 (en) 1979-11-28 1980-11-28 2-Hydroxyoxanilic acid derivatives and salts, their preparation and pharmaceutical compositions containing them.
AT80304303T ATE7385T1 (en) 1979-11-28 1980-11-28 DERIVATIVES OF 2-HYDROXYOXALACIDEANILIDE AND THEIR SALTS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
EP80304303A EP0030436B1 (en) 1979-11-28 1980-11-28 2-hydroxyoxanilic acid derivatives and salts, their preparation and pharmaceutical compositions containing them
DE8080304303T DE3067784D1 (en) 1979-11-28 1980-11-28 2-hydroxyoxanilic acid derivatives and salts, their preparation and pharmaceutical compositions containing them
US06/416,317 US4457872A (en) 1979-11-28 1982-09-09 2-Hydroxyoxanilic acid derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55151816A JPS5775953A (en) 1980-10-29 1980-10-29 Novel derivative of 2-hydroxyoxanilic acid

Publications (1)

Publication Number Publication Date
JPS5775953A true JPS5775953A (en) 1982-05-12

Family

ID=15526933

Family Applications (1)

Application Number Title Priority Date Filing Date
JP55151816A Pending JPS5775953A (en) 1979-11-28 1980-10-29 Novel derivative of 2-hydroxyoxanilic acid

Country Status (1)

Country Link
JP (1) JPS5775953A (en)

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