JPS5758609A - Drug containing nifedipine - Google Patents
Drug containing nifedipineInfo
- Publication number
- JPS5758609A JPS5758609A JP13306180A JP13306180A JPS5758609A JP S5758609 A JPS5758609 A JP S5758609A JP 13306180 A JP13306180 A JP 13306180A JP 13306180 A JP13306180 A JP 13306180A JP S5758609 A JPS5758609 A JP S5758609A
- Authority
- JP
- Japan
- Prior art keywords
- nifedipine
- pref
- carrageenan
- polyethylene glycol
- drug
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Hydrogenated Pyridines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PURPOSE: To prepare the titled drug useful as a remedy for hypertension, steno- cardia, etc., having high absorption efficiency and prolonged drug action, and containing nifedipine, carrageenan, polyethylene glycol and/or a viscous substrate.
CONSTITUTION: The objective drug contains (A) 2,6-dimethyl-4-(2-nitrophenyl)- 1,4-dihydropyridine-3,5-dicarboxylic acid dimethyl ester (nifedipine), (B) carrageenan which is a polysaccharide extracted from natural red algae, and (C) a polyethylene glycol having an average molecular weight of pref. 200W20,000 and/or a viscous substance, e.g. a mixture of a vegetable fat or oil and aluminum mono- stearate, as active component. The amount of carrageenan and that of polyethylene glycol and/or the viscous substance are 0.5W10pts.wt., pref. 1W5pts.wt., and 2W 40pts.wt., pref. 5W30pts.wt., per 1pts.wt. of nifedipine, respectively.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13306180A JPS5758609A (en) | 1980-09-26 | 1980-09-26 | Drug containing nifedipine |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13306180A JPS5758609A (en) | 1980-09-26 | 1980-09-26 | Drug containing nifedipine |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5758609A true JPS5758609A (en) | 1982-04-08 |
Family
ID=15095907
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP13306180A Pending JPS5758609A (en) | 1980-09-26 | 1980-09-26 | Drug containing nifedipine |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5758609A (en) |
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS59106418A (en) * | 1982-12-13 | 1984-06-20 | Nippon Kayaku Co Ltd | Nifedipine preparation |
FR2555048A1 (en) * | 1983-11-17 | 1985-05-24 | Nippon Shinyaku Co Ltd | PROCESS FOR THE MANUFACTURE OF NIFEDIPIN COMPOSITIONS AND NOVEL PRODUCTS THUS OBTAINED |
JPS62249922A (en) * | 1986-04-23 | 1987-10-30 | Toyo Kapuseru Kk | Method for freely controlling dissolution time of active component from gelatin-encapsulated preparation |
JPH0210114A (en) * | 1988-06-28 | 1990-01-12 | Agency Of Ind Science & Technol | Simultaneous measuring probe for flow velocity and flow direction of underground water and heat physical value of stratum utilizing heat transfer characteristic |
US5147655A (en) * | 1987-03-13 | 1992-09-15 | A/S Alfred Benzon | Oral composition containing particles comprising an active substance |
US5288500A (en) * | 1987-03-13 | 1994-02-22 | Benzon Pharma A/S | Oral composition containing particles comprising an active substance |
US6358525B1 (en) * | 1997-04-28 | 2002-03-19 | Hercules Incorporated | Sustained release polymer blend for pharmaceutical applications |
EP1186297A3 (en) * | 2000-09-05 | 2003-12-17 | Kao Corporation | Agent for preventing, improving or treating hypertension |
WO2006038661A1 (en) * | 2004-10-06 | 2006-04-13 | Eisai R & D Management Co., Ltd. | Medicinal composition, process for producing the same, and method of stabilizing dihydropyridine compound in medicinal composition |
JP2008267458A (en) * | 2007-04-18 | 2008-11-06 | Mk Seiko Co Ltd | Hollow square bar assembling and fixing structure |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5017080A (en) * | 1973-06-20 | 1975-02-22 | ||
JPS542316A (en) * | 1977-06-07 | 1979-01-09 | Yamanouchi Pharmaceut Co Ltd | Solid pharmaceutical composition containing nifedipene |
JPS5446837A (en) * | 1977-09-19 | 1979-04-13 | Kanebo Ltd | Easily absorbable nifedipin composition, its preparation, and anti-stenocardia containing the same |
-
1980
- 1980-09-26 JP JP13306180A patent/JPS5758609A/en active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5017080A (en) * | 1973-06-20 | 1975-02-22 | ||
JPS542316A (en) * | 1977-06-07 | 1979-01-09 | Yamanouchi Pharmaceut Co Ltd | Solid pharmaceutical composition containing nifedipene |
JPS5446837A (en) * | 1977-09-19 | 1979-04-13 | Kanebo Ltd | Easily absorbable nifedipin composition, its preparation, and anti-stenocardia containing the same |
Cited By (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS59106418A (en) * | 1982-12-13 | 1984-06-20 | Nippon Kayaku Co Ltd | Nifedipine preparation |
JPH0155245B2 (en) * | 1982-12-13 | 1989-11-22 | Nippon Kayaku Kk | |
FR2555048A1 (en) * | 1983-11-17 | 1985-05-24 | Nippon Shinyaku Co Ltd | PROCESS FOR THE MANUFACTURE OF NIFEDIPIN COMPOSITIONS AND NOVEL PRODUCTS THUS OBTAINED |
JPS62249922A (en) * | 1986-04-23 | 1987-10-30 | Toyo Kapuseru Kk | Method for freely controlling dissolution time of active component from gelatin-encapsulated preparation |
US5288500A (en) * | 1987-03-13 | 1994-02-22 | Benzon Pharma A/S | Oral composition containing particles comprising an active substance |
US5147655A (en) * | 1987-03-13 | 1992-09-15 | A/S Alfred Benzon | Oral composition containing particles comprising an active substance |
JPH0210114A (en) * | 1988-06-28 | 1990-01-12 | Agency Of Ind Science & Technol | Simultaneous measuring probe for flow velocity and flow direction of underground water and heat physical value of stratum utilizing heat transfer characteristic |
US6358525B1 (en) * | 1997-04-28 | 2002-03-19 | Hercules Incorporated | Sustained release polymer blend for pharmaceutical applications |
EP1186297A3 (en) * | 2000-09-05 | 2003-12-17 | Kao Corporation | Agent for preventing, improving or treating hypertension |
US6991812B2 (en) | 2000-09-05 | 2006-01-31 | Kao Corporation | Agent for preventing, improving or treating hypertension |
WO2006038661A1 (en) * | 2004-10-06 | 2006-04-13 | Eisai R & D Management Co., Ltd. | Medicinal composition, process for producing the same, and method of stabilizing dihydropyridine compound in medicinal composition |
JPWO2006038661A1 (en) * | 2004-10-06 | 2008-05-15 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | PHARMACEUTICAL COMPOSITION AND METHOD FOR PRODUCING SAME, AND METHOD FOR STABILIZING DIHYDROPYRIDINE COMPOUND IN PHARMACEUTICAL COMPOSITION |
JP4509118B2 (en) * | 2004-10-06 | 2010-07-21 | エルメッド エーザイ株式会社 | PHARMACEUTICAL COMPOSITION AND METHOD FOR PRODUCING THE SAME, AND METHOD FOR STABILIZING DIHYDROPYRIDINE COMPOUNDS |
JP2008267458A (en) * | 2007-04-18 | 2008-11-06 | Mk Seiko Co Ltd | Hollow square bar assembling and fixing structure |
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