JPS5758609A - Drug containing nifedipine - Google Patents

Drug containing nifedipine

Info

Publication number
JPS5758609A
JPS5758609A JP13306180A JP13306180A JPS5758609A JP S5758609 A JPS5758609 A JP S5758609A JP 13306180 A JP13306180 A JP 13306180A JP 13306180 A JP13306180 A JP 13306180A JP S5758609 A JPS5758609 A JP S5758609A
Authority
JP
Japan
Prior art keywords
nifedipine
pref
carrageenan
polyethylene glycol
drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP13306180A
Other languages
Japanese (ja)
Inventor
Takashi Ogino
Kenji Kono
Naoko Inaba
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kaken Pharmaceutical Co Ltd
Original Assignee
Kaken Pharmaceutical Co Ltd
Kaken Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kaken Pharmaceutical Co Ltd, Kaken Chemical Co Ltd filed Critical Kaken Pharmaceutical Co Ltd
Priority to JP13306180A priority Critical patent/JPS5758609A/en
Publication of JPS5758609A publication Critical patent/JPS5758609A/en
Pending legal-status Critical Current

Links

Landscapes

  • Hydrogenated Pyridines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PURPOSE: To prepare the titled drug useful as a remedy for hypertension, steno- cardia, etc., having high absorption efficiency and prolonged drug action, and containing nifedipine, carrageenan, polyethylene glycol and/or a viscous substrate.
CONSTITUTION: The objective drug contains (A) 2,6-dimethyl-4-(2-nitrophenyl)- 1,4-dihydropyridine-3,5-dicarboxylic acid dimethyl ester (nifedipine), (B) carrageenan which is a polysaccharide extracted from natural red algae, and (C) a polyethylene glycol having an average molecular weight of pref. 200W20,000 and/or a viscous substance, e.g. a mixture of a vegetable fat or oil and aluminum mono- stearate, as active component. The amount of carrageenan and that of polyethylene glycol and/or the viscous substance are 0.5W10pts.wt., pref. 1W5pts.wt., and 2W 40pts.wt., pref. 5W30pts.wt., per 1pts.wt. of nifedipine, respectively.
COPYRIGHT: (C)1982,JPO&Japio
JP13306180A 1980-09-26 1980-09-26 Drug containing nifedipine Pending JPS5758609A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP13306180A JPS5758609A (en) 1980-09-26 1980-09-26 Drug containing nifedipine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP13306180A JPS5758609A (en) 1980-09-26 1980-09-26 Drug containing nifedipine

Publications (1)

Publication Number Publication Date
JPS5758609A true JPS5758609A (en) 1982-04-08

Family

ID=15095907

Family Applications (1)

Application Number Title Priority Date Filing Date
JP13306180A Pending JPS5758609A (en) 1980-09-26 1980-09-26 Drug containing nifedipine

Country Status (1)

Country Link
JP (1) JPS5758609A (en)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59106418A (en) * 1982-12-13 1984-06-20 Nippon Kayaku Co Ltd Nifedipine preparation
FR2555048A1 (en) * 1983-11-17 1985-05-24 Nippon Shinyaku Co Ltd PROCESS FOR THE MANUFACTURE OF NIFEDIPIN COMPOSITIONS AND NOVEL PRODUCTS THUS OBTAINED
JPS62249922A (en) * 1986-04-23 1987-10-30 Toyo Kapuseru Kk Method for freely controlling dissolution time of active component from gelatin-encapsulated preparation
JPH0210114A (en) * 1988-06-28 1990-01-12 Agency Of Ind Science & Technol Simultaneous measuring probe for flow velocity and flow direction of underground water and heat physical value of stratum utilizing heat transfer characteristic
US5147655A (en) * 1987-03-13 1992-09-15 A/S Alfred Benzon Oral composition containing particles comprising an active substance
US5288500A (en) * 1987-03-13 1994-02-22 Benzon Pharma A/S Oral composition containing particles comprising an active substance
US6358525B1 (en) * 1997-04-28 2002-03-19 Hercules Incorporated Sustained release polymer blend for pharmaceutical applications
EP1186297A3 (en) * 2000-09-05 2003-12-17 Kao Corporation Agent for preventing, improving or treating hypertension
WO2006038661A1 (en) * 2004-10-06 2006-04-13 Eisai R & D Management Co., Ltd. Medicinal composition, process for producing the same, and method of stabilizing dihydropyridine compound in medicinal composition
JP2008267458A (en) * 2007-04-18 2008-11-06 Mk Seiko Co Ltd Hollow square bar assembling and fixing structure

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5017080A (en) * 1973-06-20 1975-02-22
JPS542316A (en) * 1977-06-07 1979-01-09 Yamanouchi Pharmaceut Co Ltd Solid pharmaceutical composition containing nifedipene
JPS5446837A (en) * 1977-09-19 1979-04-13 Kanebo Ltd Easily absorbable nifedipin composition, its preparation, and anti-stenocardia containing the same

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5017080A (en) * 1973-06-20 1975-02-22
JPS542316A (en) * 1977-06-07 1979-01-09 Yamanouchi Pharmaceut Co Ltd Solid pharmaceutical composition containing nifedipene
JPS5446837A (en) * 1977-09-19 1979-04-13 Kanebo Ltd Easily absorbable nifedipin composition, its preparation, and anti-stenocardia containing the same

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59106418A (en) * 1982-12-13 1984-06-20 Nippon Kayaku Co Ltd Nifedipine preparation
JPH0155245B2 (en) * 1982-12-13 1989-11-22 Nippon Kayaku Kk
FR2555048A1 (en) * 1983-11-17 1985-05-24 Nippon Shinyaku Co Ltd PROCESS FOR THE MANUFACTURE OF NIFEDIPIN COMPOSITIONS AND NOVEL PRODUCTS THUS OBTAINED
JPS62249922A (en) * 1986-04-23 1987-10-30 Toyo Kapuseru Kk Method for freely controlling dissolution time of active component from gelatin-encapsulated preparation
US5288500A (en) * 1987-03-13 1994-02-22 Benzon Pharma A/S Oral composition containing particles comprising an active substance
US5147655A (en) * 1987-03-13 1992-09-15 A/S Alfred Benzon Oral composition containing particles comprising an active substance
JPH0210114A (en) * 1988-06-28 1990-01-12 Agency Of Ind Science & Technol Simultaneous measuring probe for flow velocity and flow direction of underground water and heat physical value of stratum utilizing heat transfer characteristic
US6358525B1 (en) * 1997-04-28 2002-03-19 Hercules Incorporated Sustained release polymer blend for pharmaceutical applications
EP1186297A3 (en) * 2000-09-05 2003-12-17 Kao Corporation Agent for preventing, improving or treating hypertension
US6991812B2 (en) 2000-09-05 2006-01-31 Kao Corporation Agent for preventing, improving or treating hypertension
WO2006038661A1 (en) * 2004-10-06 2006-04-13 Eisai R & D Management Co., Ltd. Medicinal composition, process for producing the same, and method of stabilizing dihydropyridine compound in medicinal composition
JPWO2006038661A1 (en) * 2004-10-06 2008-05-15 エーザイ・アール・アンド・ディー・マネジメント株式会社 PHARMACEUTICAL COMPOSITION AND METHOD FOR PRODUCING SAME, AND METHOD FOR STABILIZING DIHYDROPYRIDINE COMPOUND IN PHARMACEUTICAL COMPOSITION
JP4509118B2 (en) * 2004-10-06 2010-07-21 エルメッド エーザイ株式会社 PHARMACEUTICAL COMPOSITION AND METHOD FOR PRODUCING THE SAME, AND METHOD FOR STABILIZING DIHYDROPYRIDINE COMPOUNDS
JP2008267458A (en) * 2007-04-18 2008-11-06 Mk Seiko Co Ltd Hollow square bar assembling and fixing structure

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