JPS5731640A - Dicarboxylic acid and its preparation - Google Patents
Dicarboxylic acid and its preparationInfo
- Publication number
- JPS5731640A JPS5731640A JP10354180A JP10354180A JPS5731640A JP S5731640 A JPS5731640 A JP S5731640A JP 10354180 A JP10354180 A JP 10354180A JP 10354180 A JP10354180 A JP 10354180A JP S5731640 A JPS5731640 A JP S5731640A
- Authority
- JP
- Japan
- Prior art keywords
- activity
- formula
- compound
- dicarboxylic acid
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
NEW MATERIAL:A dicarboxylic acid of formula I (X is alkylene substituted with carboxyl group; m is 0W2; n is 1W3; R is alkyl, halogen-substituted alkyl, aryl, cycloalkyl, alkoxy, aryloxy, etc.; when 2 is 2 or 3, the two Rs bonded to adjacent C atoms may together from methylenedioxy or phenyl ring), and its salt.
EXAMPLE: 2-(3-Carboxyphenyl)-3-(2-butoxyphenyl)propionic acid.
USE: The compound exhibits excellent activity to promote and normalize the immunological function, antirheumatic activity, hepatic function improving activity, antiulcer activity, etc., and is useful as pharmaceuticals.
PROCESS: The compound of formula I is prepared, e.g. by reducing the compound of formula II (X1 is carbonyl-substituted alkenylene, etc.) at 0W80°C in the presence of a catalyst.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10354180A JPS5731640A (en) | 1980-07-30 | 1980-07-30 | Dicarboxylic acid and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10354180A JPS5731640A (en) | 1980-07-30 | 1980-07-30 | Dicarboxylic acid and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5731640A true JPS5731640A (en) | 1982-02-20 |
Family
ID=14356696
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP10354180A Pending JPS5731640A (en) | 1980-07-30 | 1980-07-30 | Dicarboxylic acid and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5731640A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1985003287A1 (en) * | 1984-01-19 | 1985-08-01 | Pharmacia Ab | Novel arylacetic acid derivatives |
WO2002014262A1 (en) * | 2000-08-11 | 2002-02-21 | Kaken Pharmaceutical Co.,Ltd. | 2,3-diphenylpropionic acid derivatives or their salts, medicines or cell adhesion inhibitors containing the same, and their usage |
-
1980
- 1980-07-30 JP JP10354180A patent/JPS5731640A/en active Pending
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1985003287A1 (en) * | 1984-01-19 | 1985-08-01 | Pharmacia Ab | Novel arylacetic acid derivatives |
WO2002014262A1 (en) * | 2000-08-11 | 2002-02-21 | Kaken Pharmaceutical Co.,Ltd. | 2,3-diphenylpropionic acid derivatives or their salts, medicines or cell adhesion inhibitors containing the same, and their usage |
US7335673B2 (en) | 2000-08-11 | 2008-02-26 | Kaken Pharmaceutical Co., Ltd. | 2,3-Diphenylpropionic acid derivatives or their salts, medicines or cell adhesion inhibitors containing the same, and their usage |
JP5046466B2 (en) * | 2000-08-11 | 2012-10-10 | 科研製薬株式会社 | 2,3-Diphenylpropionic acid derivative or salt thereof, pharmaceutical and cell adhesion inhibitor using the same, and method of using the same |
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