JPS5726614A - Eye drop for adjusting intraocular pressure - Google Patents

Eye drop for adjusting intraocular pressure

Info

Publication number
JPS5726614A
JPS5726614A JP10094780A JP10094780A JPS5726614A JP S5726614 A JPS5726614 A JP S5726614A JP 10094780 A JP10094780 A JP 10094780A JP 10094780 A JP10094780 A JP 10094780A JP S5726614 A JPS5726614 A JP S5726614A
Authority
JP
Japan
Prior art keywords
eye drop
intraocular pressure
isopropylaminopropoxy
benzofuran
titled
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP10094780A
Other languages
Japanese (ja)
Other versions
JPS6411004B2 (en
Inventor
Yukihisa Ishii
Yasuo Sakai
Takao Goto
Kiyoshi Masuda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kaken Pharmaceutical Co Ltd
Original Assignee
Kaken Pharmaceutical Co Ltd
Kakenyaku Kako KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kaken Pharmaceutical Co Ltd, Kakenyaku Kako KK filed Critical Kaken Pharmaceutical Co Ltd
Priority to JP10094780A priority Critical patent/JPS5726614A/en
Priority to CA000359015A priority patent/CA1141663A/en
Priority to DE8080105202T priority patent/DE3064137D1/en
Priority to EP80105202A priority patent/EP0025202B1/en
Priority to US06/183,756 priority patent/US4382953A/en
Priority to ES494808A priority patent/ES8107021A1/en
Publication of JPS5726614A publication Critical patent/JPS5726614A/en
Publication of JPS6411004B2 publication Critical patent/JPS6411004B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

PURPOSE: The titled eye drop, containing a salt of l-2-acetyl-7-(2-hydroxy-3-isopropylaminopropoxy)benzofuran, benzalconium chloride, etc. and polyvinyl alcohol, etc., and adjusted to a specific pH.
CONSTITUTION: The titled eye drop containing 0.025W2.0W/V%, preferably 0.05W 1.0W/V%, ophthalmically acceptable water-soluble salt, e.g. hydrochloride, of l-2- acetyl-7-( 2-hydroxy-3-isopropylaminopropoxy )benzofuran, 0.001W0.1wt%, preferably 0.003W0.01W/V%, benzalconium chloride or benzetonium chloride and 0.01W2.0W/V%, preferably 0.1W1.5W/V%, polyvinyl alcohol, etc., and adjusted to a pH of 5.0W8.0, preferably 6.8W7.6. The resultant eye drop exhibits effectiveness even in an amount half that of an eye drop prepared by using a racemate of the compound (A) and has high safety and stability.
COPYRIGHT: (C)1982,JPO&Japio
JP10094780A 1979-09-06 1980-07-22 Eye drop for adjusting intraocular pressure Granted JPS5726614A (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP10094780A JPS5726614A (en) 1980-07-22 1980-07-22 Eye drop for adjusting intraocular pressure
CA000359015A CA1141663A (en) 1979-09-06 1980-08-26 Ophthalmic solution for intraocular pressure adjustment
DE8080105202T DE3064137D1 (en) 1979-09-06 1980-09-02 Ophthalmic solution for intraocular pressure adjustment
EP80105202A EP0025202B1 (en) 1979-09-06 1980-09-02 Ophthalmic solution for intraocular pressure adjustment
US06/183,756 US4382953A (en) 1979-09-06 1980-09-03 Ophthalmic solution for intraocular pressure reduction
ES494808A ES8107021A1 (en) 1979-09-06 1980-09-05 Ophthalmic solution for intraocular pressure adjustment.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10094780A JPS5726614A (en) 1980-07-22 1980-07-22 Eye drop for adjusting intraocular pressure

Publications (2)

Publication Number Publication Date
JPS5726614A true JPS5726614A (en) 1982-02-12
JPS6411004B2 JPS6411004B2 (en) 1989-02-23

Family

ID=14287540

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10094780A Granted JPS5726614A (en) 1979-09-06 1980-07-22 Eye drop for adjusting intraocular pressure

Country Status (1)

Country Link
JP (1) JPS5726614A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0273014A (en) * 1988-07-15 1990-03-13 Lab Cusi Sa Production of ophthalmic alpha-methyl-4-(2'- thienylcarbonyl) phenylacetate lysin liquid agent

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5639013A (en) * 1979-09-06 1981-04-14 Kaken Pharmaceut Co Ltd Ophthalmic solution for regulating intraocular tension

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5639013A (en) * 1979-09-06 1981-04-14 Kaken Pharmaceut Co Ltd Ophthalmic solution for regulating intraocular tension

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0273014A (en) * 1988-07-15 1990-03-13 Lab Cusi Sa Production of ophthalmic alpha-methyl-4-(2'- thienylcarbonyl) phenylacetate lysin liquid agent

Also Published As

Publication number Publication date
JPS6411004B2 (en) 1989-02-23

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