JPS57176910A - Medicinal composition - Google Patents

Medicinal composition

Info

Publication number
JPS57176910A
JPS57176910A JP56062992A JP6299281A JPS57176910A JP S57176910 A JPS57176910 A JP S57176910A JP 56062992 A JP56062992 A JP 56062992A JP 6299281 A JP6299281 A JP 6299281A JP S57176910 A JPS57176910 A JP S57176910A
Authority
JP
Japan
Prior art keywords
alkyl
compound
action
substituted
side effects
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP56062992A
Other languages
Japanese (ja)
Inventor
Takeshi Kanno
Mitsunori Gaino
Michio Yamamura
Ryuichi Ishida
Keiichi Shintomi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Seiyaku Co Ltd
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Priority to JP56062992A priority Critical patent/JPS57176910A/en
Publication of JPS57176910A publication Critical patent/JPS57176910A/en
Pending legal-status Critical Current

Links

Landscapes

  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PURPOSE: An intracranical pressure reducing agent and/or central nervous system depresant, containing a specific piperazine derivative as an active constituent, and effective for treating cerebral infarction, intracerebral hemorrhage, encephaloma, etc. with low toxicity without side effects.
CONSTITUTION: A medicinal composition containing a compound of the formula (R1 is H, alkyl, alkyl-substituted sulfonyl, etc.; R2 is H, alkyl, alkoxylcarbonyl- substituted alkyl, etc.; ring A is phenyl, alkyl-substituted phenyl or halogen- substitued phneyl; n is an integer 2W6) or a pharmacologically accepatable acid addition salt thereof as an active constituent. The compound of the formula has a powerful intracranial pressure reducing action with a long duration of action without causing side effects, e.g. the intracranial pressure rebound phenomenon. The compound is useful as a tranquilizer, analgesic agent, etc. due to the central nervous system depressant action. The oral or parenteral administration is possible, and the dialy dose thereof is about 0.05W50mg/kg.
COPYRIGHT: (C)1982,JPO&Japio
JP56062992A 1981-04-24 1981-04-24 Medicinal composition Pending JPS57176910A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP56062992A JPS57176910A (en) 1981-04-24 1981-04-24 Medicinal composition

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56062992A JPS57176910A (en) 1981-04-24 1981-04-24 Medicinal composition

Publications (1)

Publication Number Publication Date
JPS57176910A true JPS57176910A (en) 1982-10-30

Family

ID=13216368

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56062992A Pending JPS57176910A (en) 1981-04-24 1981-04-24 Medicinal composition

Country Status (1)

Country Link
JP (1) JPS57176910A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008543792A (en) * 2005-06-17 2008-12-04 アンドルシェルシュ・インコーポレイテッド Helix 12-directed non-steroidal antiandrogen

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008543792A (en) * 2005-06-17 2008-12-04 アンドルシェルシュ・インコーポレイテッド Helix 12-directed non-steroidal antiandrogen

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