JPS5716818A - Steroid fatty emulsion - Google Patents

Steroid fatty emulsion

Info

Publication number
JPS5716818A
JPS5716818A JP6285081A JP6285081A JPS5716818A JP S5716818 A JPS5716818 A JP S5716818A JP 6285081 A JP6285081 A JP 6285081A JP 6285081 A JP6285081 A JP 6285081A JP S5716818 A JPS5716818 A JP S5716818A
Authority
JP
Japan
Prior art keywords
steroid
inflammatory activity
phospholipid
fatty emulsion
soybean oil
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP6285081A
Other languages
Japanese (ja)
Other versions
JPH0128727B2 (en
Inventor
Yutaka Mizushima
Kazumasa Yokoyama
Kiichiro Nabeta
Noboru Yamada
Tadakazu Suyama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Tanabe Pharma Corp
Original Assignee
Green Cross Corp Japan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Green Cross Corp Japan filed Critical Green Cross Corp Japan
Priority to JP6285081A priority Critical patent/JPS5716818A/en
Publication of JPS5716818A publication Critical patent/JPS5716818A/en
Publication of JPH0128727B2 publication Critical patent/JPH0128727B2/ja
Granted legal-status Critical Current

Links

Abstract

PURPOSE: A steroid pharmaceutical, containing a steroid having an anti-inflammatory activity as an active constituent, and preferably soybean oil, a phospholipid and water, in the form of a fatty emulsion, and capable of exhibiting a high anti- inflammatory activity even in a small dose without side effects.
CONSTITUTION: A steroid fatty emulsion containing a steroid having an anti- inflammatory activity selected from stearates and myristates of dexamethasone, hydrocortisone and prednisone. A preferred pharmaceutical contains 5W50W/V% soybean oil, a phospholipid in an amount to give a weight ratio between the soybean oil and the phospholipid of 100:1W50 and a suitable amount of water. An isotonizing agent, emulsifying assistant, emulsion stabilizer, etc. may be added to the pharmaceutical if necessary. The resultant fatty emulsion is preferably administered parenterally, more preferably intravenously, and exhibits a high and lasting anti- inflammatory activity even in a small dose.
COPYRIGHT: (C)1982,JPO&Japio
JP6285081A 1981-04-25 1981-04-25 Steroid fatty emulsion Granted JPS5716818A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP6285081A JPS5716818A (en) 1981-04-25 1981-04-25 Steroid fatty emulsion

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6285081A JPS5716818A (en) 1981-04-25 1981-04-25 Steroid fatty emulsion

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP55064875A Division JPS609726B2 (en) 1980-05-15 1980-05-15 steroid preparations

Publications (2)

Publication Number Publication Date
JPS5716818A true JPS5716818A (en) 1982-01-28
JPH0128727B2 JPH0128727B2 (en) 1989-06-05

Family

ID=13212190

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6285081A Granted JPS5716818A (en) 1981-04-25 1981-04-25 Steroid fatty emulsion

Country Status (1)

Country Link
JP (1) JPS5716818A (en)

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58162516A (en) * 1982-03-20 1983-09-27 Fujisawa Pharmaceut Co Ltd Steroid-containing water-in-oil type emulsion
JPS5913720A (en) * 1982-07-15 1984-01-24 Green Cross Corp:The Fluorobiprofen fat emulsion
WO1984002076A1 (en) * 1982-11-26 1984-06-07 Fluidcarbon International Ab Method of preparing controlled-release preparations for biologically active materials and resulting compositions
JPS59122423A (en) * 1982-12-28 1984-07-14 Green Cross Corp:The Carcinostatic-containing fatty emulsion
JPS59141518A (en) * 1983-02-03 1984-08-14 Taisho Pharmaceut Co Ltd Prostaglandin fat emulsion
JPS59216820A (en) * 1983-05-20 1984-12-06 Taisho Pharmaceut Co Ltd Fat emulsion of prostaglandin
JPS601122A (en) * 1983-06-20 1985-01-07 Green Cross Corp:The Fat emulsion of biphenylylpropionic acid derivative
JPS62192322A (en) * 1986-02-13 1987-08-22 カビ・フアーマシア・アクチエボラーグ Novel pharmaceutical composition
JPS62294617A (en) * 1986-06-16 1987-12-22 Green Cross Corp:The Rejection suppressive agent for transplanted piece
JPH01143826A (en) * 1987-11-30 1989-06-06 Taisho Pharmaceut Co Ltd Fat emulsion of fine particle
JPH04101461U (en) * 1991-02-12 1992-09-02 清水建設株式会社 Lightweight panel installation equipment
KR100362924B1 (en) * 2000-01-11 2002-11-30 주식회사 동구약품 Epidermal preparations
JP2009538879A (en) * 2006-06-01 2009-11-12 ノバガリ ファルマ エスア Use of steroid prodrugs to treat posterior eye diseases

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4950124A (en) * 1972-09-27 1974-05-15
JPS56135416A (en) * 1980-03-27 1981-10-22 Mitsubishi Chem Ind Ltd Pharmaceutical preparation for skin
JPS6323971A (en) * 1986-07-11 1988-02-01 ハ−キユリ−ズ・インコ−ポレイテツド Primer coating composition for cycloolefin polymer product

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4950124A (en) * 1972-09-27 1974-05-15
JPS56135416A (en) * 1980-03-27 1981-10-22 Mitsubishi Chem Ind Ltd Pharmaceutical preparation for skin
JPS6323971A (en) * 1986-07-11 1988-02-01 ハ−キユリ−ズ・インコ−ポレイテツド Primer coating composition for cycloolefin polymer product

Cited By (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58162516A (en) * 1982-03-20 1983-09-27 Fujisawa Pharmaceut Co Ltd Steroid-containing water-in-oil type emulsion
JPH0149128B2 (en) * 1982-03-20 1989-10-23 Fujisawa Pharmaceutical Co
JPH0138767B2 (en) * 1982-07-15 1989-08-16 Midori Juji Kk
JPS5913720A (en) * 1982-07-15 1984-01-24 Green Cross Corp:The Fluorobiprofen fat emulsion
WO1984002076A1 (en) * 1982-11-26 1984-06-07 Fluidcarbon International Ab Method of preparing controlled-release preparations for biologically active materials and resulting compositions
JPS59122423A (en) * 1982-12-28 1984-07-14 Green Cross Corp:The Carcinostatic-containing fatty emulsion
JPH0518806B2 (en) * 1982-12-28 1993-03-15 Green Cross Corp
JPS59141518A (en) * 1983-02-03 1984-08-14 Taisho Pharmaceut Co Ltd Prostaglandin fat emulsion
JPH0157095B2 (en) * 1983-02-03 1989-12-04 Taisho Seiyaku Kk
JPS59216820A (en) * 1983-05-20 1984-12-06 Taisho Pharmaceut Co Ltd Fat emulsion of prostaglandin
JPH0157096B2 (en) * 1983-05-20 1989-12-04 Taisho Seiyaku Kk
JPH0437801B2 (en) * 1983-06-20 1992-06-22 Midori Juji Kk
JPS601122A (en) * 1983-06-20 1985-01-07 Green Cross Corp:The Fat emulsion of biphenylylpropionic acid derivative
JPS62192322A (en) * 1986-02-13 1987-08-22 カビ・フアーマシア・アクチエボラーグ Novel pharmaceutical composition
JPS62294617A (en) * 1986-06-16 1987-12-22 Green Cross Corp:The Rejection suppressive agent for transplanted piece
JPH01143826A (en) * 1987-11-30 1989-06-06 Taisho Pharmaceut Co Ltd Fat emulsion of fine particle
JPH04101461U (en) * 1991-02-12 1992-09-02 清水建設株式会社 Lightweight panel installation equipment
KR100362924B1 (en) * 2000-01-11 2002-11-30 주식회사 동구약품 Epidermal preparations
JP2009538879A (en) * 2006-06-01 2009-11-12 ノバガリ ファルマ エスア Use of steroid prodrugs to treat posterior eye diseases
US9192567B2 (en) 2006-06-01 2015-11-24 Santen Sas Method for treating eye disease or conditions affecting the posterior segment of the eye

Also Published As

Publication number Publication date
JPH0128727B2 (en) 1989-06-05

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Legal Events

Date Code Title Description
EXPY Cancellation because of completion of term
R154 Certificate of patent or utility model (reissue)

Free format text: JAPANESE INTERMEDIATE CODE: R154