JPS57165392A - Long-acting cephalexin tablet - Google Patents

Long-acting cephalexin tablet

Info

Publication number
JPS57165392A
JPS57165392A JP5211781A JP5211781A JPS57165392A JP S57165392 A JPS57165392 A JP S57165392A JP 5211781 A JP5211781 A JP 5211781A JP 5211781 A JP5211781 A JP 5211781A JP S57165392 A JPS57165392 A JP S57165392A
Authority
JP
Japan
Prior art keywords
cephalexin
tablet
acting
fats
oils
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP5211781A
Other languages
Japanese (ja)
Other versions
JPS6321649B2 (en
Inventor
Masaki Hasegawa
Mutsuhiro Mori
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toyo Jozo KK
Original Assignee
Toyo Jozo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyo Jozo KK filed Critical Toyo Jozo KK
Priority to JP5211781A priority Critical patent/JPS57165392A/en
Publication of JPS57165392A publication Critical patent/JPS57165392A/en
Publication of JPS6321649B2 publication Critical patent/JPS6321649B2/ja
Granted legal-status Critical Current

Links

Abstract

PURPOSE: To prepare a high quality long-acting cephalexin tablet having extremely easily controllable rate of cephalexin dissolution, by compounding cephalexin with oils and fats.
CONSTITUTION: Cephalexin is mixed with ≥10% W/W oils and fats (e.g. higher fatty acid, higher alcohol, alcohol ester, etc.) and with a vehicle such as microcrystalline cellulose and a lubricant such as magnesium stearate, and the mixture is pressed, formed to granules passing through a 20 mesh sieve, and subjected to the slug-forming process to obtain a high-quality long-acting tablet. The rate of dissolution of cephalexin can be controlled by selecting the kind of the oils and fats and the number of the times of the slug formation process. The disintegrable slow-acting preparation thus obtained can release the contained cephalexin entirely, and has higher bioavailability than the conventional delayed dissolution tablet. The preparation can contain 500mg titer in 1W2 tablets, and it is unnecessary to make in the form of a particular cored tablet.
COPYRIGHT: (C)1982,JPO&Japio
JP5211781A 1981-04-06 1981-04-06 Long-acting cephalexin tablet Granted JPS57165392A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP5211781A JPS57165392A (en) 1981-04-06 1981-04-06 Long-acting cephalexin tablet

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP5211781A JPS57165392A (en) 1981-04-06 1981-04-06 Long-acting cephalexin tablet

Publications (2)

Publication Number Publication Date
JPS57165392A true JPS57165392A (en) 1982-10-12
JPS6321649B2 JPS6321649B2 (en) 1988-05-09

Family

ID=12905924

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5211781A Granted JPS57165392A (en) 1981-04-06 1981-04-06 Long-acting cephalexin tablet

Country Status (1)

Country Link
JP (1) JPS57165392A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003501375A (en) * 1999-06-04 2003-01-14 アルザ・コーポレーション Implantable gel composition and method of manufacture
KR100388932B1 (en) * 1994-10-17 2003-09-19 악조 노벨 엔.브이. Solid pharmaceutical compositions containing excipients capable of binding water
US7514552B2 (en) 2003-05-30 2009-04-07 Asahi Kasei Chemicals Corporation Cellulose powder

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS517118A (en) * 1974-06-04 1976-01-21 Klinge Co Chem Pharm Fab CHENJOZAINOSEIZOHOHO
JPS5545601A (en) * 1978-09-26 1980-03-31 Toyo Jozo Co Ltd Long-acting cephalexin and its preparation
JPS55104211A (en) * 1979-02-05 1980-08-09 Boehringer Mannheim Gmbh Manufacture of molded body retarding active substance release

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS517118A (en) * 1974-06-04 1976-01-21 Klinge Co Chem Pharm Fab CHENJOZAINOSEIZOHOHO
JPS5545601A (en) * 1978-09-26 1980-03-31 Toyo Jozo Co Ltd Long-acting cephalexin and its preparation
JPS55104211A (en) * 1979-02-05 1980-08-09 Boehringer Mannheim Gmbh Manufacture of molded body retarding active substance release

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100388932B1 (en) * 1994-10-17 2003-09-19 악조 노벨 엔.브이. Solid pharmaceutical compositions containing excipients capable of binding water
JP2003501375A (en) * 1999-06-04 2003-01-14 アルザ・コーポレーション Implantable gel composition and method of manufacture
US7514552B2 (en) 2003-05-30 2009-04-07 Asahi Kasei Chemicals Corporation Cellulose powder

Also Published As

Publication number Publication date
JPS6321649B2 (en) 1988-05-09

Similar Documents

Publication Publication Date Title
US5171329A (en) Method for manufacturing a candle
US5194172A (en) Aerated and freezer bar soap compositions containing sucrose as a mildness aid and a processing aid
DE69922824T2 (en) SOAP PIECES WITH LITTLE OR NO SYNTHETIC TENSID
EP0028005B1 (en) Cleaning tablet for dental prostheses
RU2383586C1 (en) Method for production of calcium soaps for animal feeds
JPS5618914A (en) Ubidecarenone composition having good absorbability
WO1993013760A1 (en) Pharmaceutical preparation in the form of an effervescent and/or disintegrating tablet or an instant granulate, and process for producing it
JPS5558060A (en) Preparation of hard butter
JPS57165392A (en) Long-acting cephalexin tablet
EP0109721A2 (en) Margarine fat blend
FI68755B (en) FOERFARANDE FOER FRAMSTAELLNING AV EN NAERINGSFETTPRODUKT INNEHAOLLANDE KNAPPT AV TRANS-ISOMERER
US2914546A (en) Interesterified mixed glyceryl esters
JPS5315308A (en) Collection of fatty acid esters and cholesterol
DE3067504D1 (en) Process for the production of fatty acid soaps from sludge by extraction and subsequent saponifying
JPS5635967A (en) Food-flavoring composition
JPS57151669A (en) Gelatinizing agent for waste oil, and method for solidifying waste oil in gel form
Jee Composition of the fat extracted from the seeds of Theobroma bicolor
ITMI970057A1 (en) PROCEDURE FOR MAKING CANDLES AND WAXY MATERIAL FOR MAKING CANDLES
US3615588A (en) Glyceride mixture and plastic edible fats prepared therefrom
JPS55120748A (en) Preparation of cocoa powder readily soluble in cold water
WO1997035954A3 (en) Soap making process
JPH01207258A (en) Method for removing acid
DE1618896C (en) Process for the preparation of a solid substance containing ethyl alcohol
OA12967A (en) Hard bouillon tablet or cube.
DE2352393A1 (en) PROCEDURE FOR GRANULATING A DETERGENT COMPOSITION