JPS57165392A - Long-acting cephalexin tablet - Google Patents
Long-acting cephalexin tabletInfo
- Publication number
- JPS57165392A JPS57165392A JP5211781A JP5211781A JPS57165392A JP S57165392 A JPS57165392 A JP S57165392A JP 5211781 A JP5211781 A JP 5211781A JP 5211781 A JP5211781 A JP 5211781A JP S57165392 A JPS57165392 A JP S57165392A
- Authority
- JP
- Japan
- Prior art keywords
- cephalexin
- tablet
- acting
- fats
- oils
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
PURPOSE: To prepare a high quality long-acting cephalexin tablet having extremely easily controllable rate of cephalexin dissolution, by compounding cephalexin with oils and fats.
CONSTITUTION: Cephalexin is mixed with ≥10% W/W oils and fats (e.g. higher fatty acid, higher alcohol, alcohol ester, etc.) and with a vehicle such as microcrystalline cellulose and a lubricant such as magnesium stearate, and the mixture is pressed, formed to granules passing through a 20 mesh sieve, and subjected to the slug-forming process to obtain a high-quality long-acting tablet. The rate of dissolution of cephalexin can be controlled by selecting the kind of the oils and fats and the number of the times of the slug formation process. The disintegrable slow-acting preparation thus obtained can release the contained cephalexin entirely, and has higher bioavailability than the conventional delayed dissolution tablet. The preparation can contain 500mg titer in 1W2 tablets, and it is unnecessary to make in the form of a particular cored tablet.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5211781A JPS57165392A (en) | 1981-04-06 | 1981-04-06 | Long-acting cephalexin tablet |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5211781A JPS57165392A (en) | 1981-04-06 | 1981-04-06 | Long-acting cephalexin tablet |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57165392A true JPS57165392A (en) | 1982-10-12 |
JPS6321649B2 JPS6321649B2 (en) | 1988-05-09 |
Family
ID=12905924
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP5211781A Granted JPS57165392A (en) | 1981-04-06 | 1981-04-06 | Long-acting cephalexin tablet |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57165392A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2003501375A (en) * | 1999-06-04 | 2003-01-14 | アルザ・コーポレーション | Implantable gel composition and method of manufacture |
KR100388932B1 (en) * | 1994-10-17 | 2003-09-19 | 악조 노벨 엔.브이. | Solid pharmaceutical compositions containing excipients capable of binding water |
US7514552B2 (en) | 2003-05-30 | 2009-04-07 | Asahi Kasei Chemicals Corporation | Cellulose powder |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS517118A (en) * | 1974-06-04 | 1976-01-21 | Klinge Co Chem Pharm Fab | CHENJOZAINOSEIZOHOHO |
JPS5545601A (en) * | 1978-09-26 | 1980-03-31 | Toyo Jozo Co Ltd | Long-acting cephalexin and its preparation |
JPS55104211A (en) * | 1979-02-05 | 1980-08-09 | Boehringer Mannheim Gmbh | Manufacture of molded body retarding active substance release |
-
1981
- 1981-04-06 JP JP5211781A patent/JPS57165392A/en active Granted
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS517118A (en) * | 1974-06-04 | 1976-01-21 | Klinge Co Chem Pharm Fab | CHENJOZAINOSEIZOHOHO |
JPS5545601A (en) * | 1978-09-26 | 1980-03-31 | Toyo Jozo Co Ltd | Long-acting cephalexin and its preparation |
JPS55104211A (en) * | 1979-02-05 | 1980-08-09 | Boehringer Mannheim Gmbh | Manufacture of molded body retarding active substance release |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100388932B1 (en) * | 1994-10-17 | 2003-09-19 | 악조 노벨 엔.브이. | Solid pharmaceutical compositions containing excipients capable of binding water |
JP2003501375A (en) * | 1999-06-04 | 2003-01-14 | アルザ・コーポレーション | Implantable gel composition and method of manufacture |
US7514552B2 (en) | 2003-05-30 | 2009-04-07 | Asahi Kasei Chemicals Corporation | Cellulose powder |
Also Published As
Publication number | Publication date |
---|---|
JPS6321649B2 (en) | 1988-05-09 |
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