JPS57134448A - Production of diaralkylamine - Google Patents

Production of diaralkylamine

Info

Publication number
JPS57134448A
JPS57134448A JP2044781A JP2044781A JPS57134448A JP S57134448 A JPS57134448 A JP S57134448A JP 2044781 A JP2044781 A JP 2044781A JP 2044781 A JP2044781 A JP 2044781A JP S57134448 A JPS57134448 A JP S57134448A
Authority
JP
Japan
Prior art keywords
formula
compound
derivative
diaralkylamine
drugs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2044781A
Other languages
Japanese (ja)
Other versions
JPS6126982B2 (en
Inventor
Iwao Tanimoto
Kazuhiro Maruyama
Keiko Kushioka
Masahiko Kato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to JP2044781A priority Critical patent/JPS57134448A/en
Publication of JPS57134448A publication Critical patent/JPS57134448A/en
Publication of JPS6126982B2 publication Critical patent/JPS6126982B2/ja
Granted legal-status Critical Current

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PURPOSE: The reaction of pyruvic acid derivative or benzaldehyde derivative with phenylalkylamine derivative is followed by reduction of the product to produce the titled compound used as a starting material for drugs in high yield.
CONSTITUTION: A compound of formula 2 (R is H, hydroxyl, halogen, 1W5C alkyl; n is 1W4) or formula 3 is made to react with a compound of formula 4 (R' is R; m is n) to give a compound of formula 5[X is CH, (CH2)n CH; Y is (CH2)m]. The reaction is conducted in an organic solvent such as DMSO at a temperature over 80°C, preferably at 130W160°C. Then, the compound of formula 5 is reduced, preferably with sodium cyanoborohydride to give the diaralkylamine of formula 1 (l, m is 1W4). The compound of formula 1, especially a diphenethylamine derivative is used as a starting material for drugs.
COPYRIGHT: (C)1982,JPO&Japio
JP2044781A 1981-02-14 1981-02-14 Production of diaralkylamine Granted JPS57134448A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2044781A JPS57134448A (en) 1981-02-14 1981-02-14 Production of diaralkylamine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2044781A JPS57134448A (en) 1981-02-14 1981-02-14 Production of diaralkylamine

Publications (2)

Publication Number Publication Date
JPS57134448A true JPS57134448A (en) 1982-08-19
JPS6126982B2 JPS6126982B2 (en) 1986-06-23

Family

ID=12027305

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2044781A Granted JPS57134448A (en) 1981-02-14 1981-02-14 Production of diaralkylamine

Country Status (1)

Country Link
JP (1) JPS57134448A (en)

Also Published As

Publication number Publication date
JPS6126982B2 (en) 1986-06-23

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