JPS57126492A - 7-amino-3-halogenomethyl-delta3-cephem-4-carboxylic acids and their preparations - Google Patents
7-amino-3-halogenomethyl-delta3-cephem-4-carboxylic acids and their preparationsInfo
- Publication number
- JPS57126492A JPS57126492A JP1216181A JP1216181A JPS57126492A JP S57126492 A JPS57126492 A JP S57126492A JP 1216181 A JP1216181 A JP 1216181A JP 1216181 A JP1216181 A JP 1216181A JP S57126492 A JPS57126492 A JP S57126492A
- Authority
- JP
- Japan
- Prior art keywords
- acid
- salt
- cephem
- amino
- delta3
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Cephalosporin Compounds (AREA)
Abstract
NEW MATERIAL:A compound shown by the formulaI(R1 is H or methoxy; X is halogen) or its salt.
EXAMPLE: 7-Amino-3-iodomethyl-Δ3-cephem-4-carboxylic acid.
USE: A compound useful as an intermediate for cephalosporin type compound, and its salt.
PROCESS: A 7-aminocephalosporanic acid shown by the formula II or its salt is reacted with a hydrohalogenic acid or its salt in the presence of sulfuric acid, an alkylsulfonic acid, arylsulfonic acid, halosulfonic acid, or haloalkylsulfonic acid in the absence of a solvent or in an organic solvent (e.g., acetone, acetonitrile, sulfolane, etc.), to give a compound shown by the formulaI.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56012161A JPS6052754B2 (en) | 1981-01-29 | 1981-01-29 | 7-amino-3-halogenomethyl-△↑3-cephem-4-carboxylic acids and their production method |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56012161A JPS6052754B2 (en) | 1981-01-29 | 1981-01-29 | 7-amino-3-halogenomethyl-△↑3-cephem-4-carboxylic acids and their production method |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57126492A true JPS57126492A (en) | 1982-08-06 |
JPS6052754B2 JPS6052754B2 (en) | 1985-11-21 |
Family
ID=11797719
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP56012161A Expired JPS6052754B2 (en) | 1981-01-29 | 1981-01-29 | 7-amino-3-halogenomethyl-△↑3-cephem-4-carboxylic acids and their production method |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6052754B2 (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63501851A (en) * | 1985-10-31 | 1988-07-28 | アンジオ−メデイカル コ−ポレイシヨン | Supercritical fluid extraction of animal-derived substances |
JPH07165765A (en) * | 1984-11-23 | 1995-06-27 | Biochem Gmbh | New preparation of cephalosporin derivative |
US5571909A (en) * | 1993-06-09 | 1996-11-05 | Korea Institute Of Science And Technology | Cephalosporin compounds and processes for preparing thereof |
CN105131018A (en) * | 2015-09-23 | 2015-12-09 | 浙江华方药业股份有限公司 | Preparation method of ceftezole acid |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS646884A (en) * | 1987-06-30 | 1989-01-11 | Nec Corp | Variable constant type chirp signal generating circuit |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS549296A (en) * | 1977-04-02 | 1979-01-24 | Hoechst Ag | Cephem derivative and its preparation |
JPS559048A (en) * | 1978-07-06 | 1980-01-22 | Toyama Chem Co Ltd | Novel preparation of 7-substituted or non-substituted amino-3-substituted thiomethylcephem carboxylic acids |
JPS5686187A (en) * | 1979-11-19 | 1981-07-13 | Fujisawa Pharmaceut Co Ltd | 7-acylamino-3-vinylcephalosporanic acid derivative and its preparation |
-
1981
- 1981-01-29 JP JP56012161A patent/JPS6052754B2/en not_active Expired
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS549296A (en) * | 1977-04-02 | 1979-01-24 | Hoechst Ag | Cephem derivative and its preparation |
JPS559048A (en) * | 1978-07-06 | 1980-01-22 | Toyama Chem Co Ltd | Novel preparation of 7-substituted or non-substituted amino-3-substituted thiomethylcephem carboxylic acids |
JPS5686187A (en) * | 1979-11-19 | 1981-07-13 | Fujisawa Pharmaceut Co Ltd | 7-acylamino-3-vinylcephalosporanic acid derivative and its preparation |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH07165765A (en) * | 1984-11-23 | 1995-06-27 | Biochem Gmbh | New preparation of cephalosporin derivative |
JPS63501851A (en) * | 1985-10-31 | 1988-07-28 | アンジオ−メデイカル コ−ポレイシヨン | Supercritical fluid extraction of animal-derived substances |
US5571909A (en) * | 1993-06-09 | 1996-11-05 | Korea Institute Of Science And Technology | Cephalosporin compounds and processes for preparing thereof |
CN105131018A (en) * | 2015-09-23 | 2015-12-09 | 浙江华方药业股份有限公司 | Preparation method of ceftezole acid |
Also Published As
Publication number | Publication date |
---|---|
JPS6052754B2 (en) | 1985-11-21 |
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