JPS57118573A - N-(2-thiazolyl)carbamate derivative, its preparation, and drug composition comprising it - Google Patents

N-(2-thiazolyl)carbamate derivative, its preparation, and drug composition comprising it

Info

Publication number
JPS57118573A
JPS57118573A JP213481A JP213481A JPS57118573A JP S57118573 A JPS57118573 A JP S57118573A JP 213481 A JP213481 A JP 213481A JP 213481 A JP213481 A JP 213481A JP S57118573 A JPS57118573 A JP S57118573A
Authority
JP
Japan
Prior art keywords
thiazolyl
carbamate derivative
preparation
drug composition
formulai
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP213481A
Other languages
Japanese (ja)
Other versions
JPH0254354B2 (en
Inventor
Isao Sakano
Tatsuro Yokoyama
Seitaro Kajitani
Yutaka Okazaki
Hiroshi Tokuda
Hiroshi Kawamo
Mikio Kumakura
Takuo Nakano
Akira Awaya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsui Toatsu Chemicals Inc
Original Assignee
Mitsui Toatsu Chemicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsui Toatsu Chemicals Inc filed Critical Mitsui Toatsu Chemicals Inc
Priority to JP213481A priority Critical patent/JPS57118573A/en
Priority to JP56003000A priority patent/JPS57116067A/en
Priority to IT25957/81A priority patent/IT1142649B/en
Priority to GB8200577A priority patent/GB2096596A/en
Priority to PCT/JP1982/000009 priority patent/WO1982002385A1/en
Publication of JPS57118573A publication Critical patent/JPS57118573A/en
Publication of JPH0254354B2 publication Critical patent/JPH0254354B2/ja
Granted legal-status Critical Current

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  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:An N-(2-thiazolyl)carbamate derivative shown by the formulaI (R is H, lower alkyl, cycloalkyl, thienyl, furyl, pyridyl).
EXAMPLE: 2,2,2-Trichloroethyl N-[4-(4-pyridyl)thiazole-2-yl)carbamate.
USE: A drug effective for immune diseases such as rheumatoid arthrits, also useful for viral diseases or carcinostatic immunotherapy, having immune adjusting ability and antarthritic action. Having low toxicity.
PROCESS: For example, an aminothizole shown by the formula II is reacted with 2,2-chloroformic acid 2,2,2-tricyloroethyl ester in a solvent such as benzene, etc., to give a compound shown by the formulaI.
COPYRIGHT: (C)1982,JPO&Japio
JP213481A 1981-01-08 1981-01-12 N-(2-thiazolyl)carbamate derivative, its preparation, and drug composition comprising it Granted JPS57118573A (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP213481A JPS57118573A (en) 1981-01-12 1981-01-12 N-(2-thiazolyl)carbamate derivative, its preparation, and drug composition comprising it
JP56003000A JPS57116067A (en) 1981-01-12 1981-01-12 Novel 8-quinolinesulfonyl derivative, its synthesis and use
IT25957/81A IT1142649B (en) 1981-01-08 1981-12-31 N 4 Phenyl 2 thiazolyl carbamate derivs.
GB8200577A GB2096596A (en) 1981-01-12 1982-01-08 8-quinolinesulfonyl derivatives and their synthesis and use as coupling agents in nucleotide chemistry
PCT/JP1982/000009 WO1982002385A1 (en) 1981-01-12 1982-01-12 N-(2-thiazolyl)carbamate derivatives,process for their preparation,and medicinal composition containing same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP213481A JPS57118573A (en) 1981-01-12 1981-01-12 N-(2-thiazolyl)carbamate derivative, its preparation, and drug composition comprising it

Publications (2)

Publication Number Publication Date
JPS57118573A true JPS57118573A (en) 1982-07-23
JPH0254354B2 JPH0254354B2 (en) 1990-11-21

Family

ID=11520857

Family Applications (1)

Application Number Title Priority Date Filing Date
JP213481A Granted JPS57118573A (en) 1981-01-08 1981-01-12 N-(2-thiazolyl)carbamate derivative, its preparation, and drug composition comprising it

Country Status (1)

Country Link
JP (1) JPS57118573A (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5461172A (en) * 1977-10-19 1979-05-17 Fabre Sa Pierre Novel 44phenyll22aminothiazole derivative* its manufacture and immunity stimulant containing it

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5461172A (en) * 1977-10-19 1979-05-17 Fabre Sa Pierre Novel 44phenyll22aminothiazole derivative* its manufacture and immunity stimulant containing it

Also Published As

Publication number Publication date
JPH0254354B2 (en) 1990-11-21

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