JPS57118573A - N-(2-thiazolyl)carbamate derivative, its preparation, and drug composition comprising it - Google Patents
N-(2-thiazolyl)carbamate derivative, its preparation, and drug composition comprising itInfo
- Publication number
- JPS57118573A JPS57118573A JP213481A JP213481A JPS57118573A JP S57118573 A JPS57118573 A JP S57118573A JP 213481 A JP213481 A JP 213481A JP 213481 A JP213481 A JP 213481A JP S57118573 A JPS57118573 A JP S57118573A
- Authority
- JP
- Japan
- Prior art keywords
- thiazolyl
- carbamate derivative
- preparation
- drug composition
- formulai
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:An N-(2-thiazolyl)carbamate derivative shown by the formulaI (R is H, lower alkyl, cycloalkyl, thienyl, furyl, pyridyl).
EXAMPLE: 2,2,2-Trichloroethyl N-[4-(4-pyridyl)thiazole-2-yl)carbamate.
USE: A drug effective for immune diseases such as rheumatoid arthrits, also useful for viral diseases or carcinostatic immunotherapy, having immune adjusting ability and antarthritic action. Having low toxicity.
PROCESS: For example, an aminothizole shown by the formula II is reacted with 2,2-chloroformic acid 2,2,2-tricyloroethyl ester in a solvent such as benzene, etc., to give a compound shown by the formulaI.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP213481A JPS57118573A (en) | 1981-01-12 | 1981-01-12 | N-(2-thiazolyl)carbamate derivative, its preparation, and drug composition comprising it |
JP56003000A JPS57116067A (en) | 1981-01-12 | 1981-01-12 | Novel 8-quinolinesulfonyl derivative, its synthesis and use |
IT25957/81A IT1142649B (en) | 1981-01-08 | 1981-12-31 | N 4 Phenyl 2 thiazolyl carbamate derivs. |
GB8200577A GB2096596A (en) | 1981-01-12 | 1982-01-08 | 8-quinolinesulfonyl derivatives and their synthesis and use as coupling agents in nucleotide chemistry |
PCT/JP1982/000009 WO1982002385A1 (en) | 1981-01-12 | 1982-01-12 | N-(2-thiazolyl)carbamate derivatives,process for their preparation,and medicinal composition containing same |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP213481A JPS57118573A (en) | 1981-01-12 | 1981-01-12 | N-(2-thiazolyl)carbamate derivative, its preparation, and drug composition comprising it |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57118573A true JPS57118573A (en) | 1982-07-23 |
JPH0254354B2 JPH0254354B2 (en) | 1990-11-21 |
Family
ID=11520857
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP213481A Granted JPS57118573A (en) | 1981-01-08 | 1981-01-12 | N-(2-thiazolyl)carbamate derivative, its preparation, and drug composition comprising it |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57118573A (en) |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5461172A (en) * | 1977-10-19 | 1979-05-17 | Fabre Sa Pierre | Novel 44phenyll22aminothiazole derivative* its manufacture and immunity stimulant containing it |
-
1981
- 1981-01-12 JP JP213481A patent/JPS57118573A/en active Granted
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5461172A (en) * | 1977-10-19 | 1979-05-17 | Fabre Sa Pierre | Novel 44phenyll22aminothiazole derivative* its manufacture and immunity stimulant containing it |
Also Published As
Publication number | Publication date |
---|---|
JPH0254354B2 (en) | 1990-11-21 |
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