JPS57118571A - 1-ethyl-2,3-dioxopiperazine - Google Patents
1-ethyl-2,3-dioxopiperazineInfo
- Publication number
- JPS57118571A JPS57118571A JP18840881A JP18840881A JPS57118571A JP S57118571 A JPS57118571 A JP S57118571A JP 18840881 A JP18840881 A JP 18840881A JP 18840881 A JP18840881 A JP 18840881A JP S57118571 A JPS57118571 A JP S57118571A
- Authority
- JP
- Japan
- Prior art keywords
- ethyl
- formula
- acid
- dioxopiperazine
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:1-Ethyl-2,3-dioxopiperazine shown by the formula.
USE: An intermediate for synthesizing a novel penicillin and a cephalosporin, namely 6-aminoacylaminopenicillanic acid and a compound obtaned by introducing 4-ethyl-2,3-dioxo-1-piperazinyl-carbonyl group to an amino group of 7-aminoacylaminocephalosporanic acid, which are capable of exhibiting effective antibacterial activity against even drug resistant bacteria, showing effective and safe effect in a living body.
PROCESS: A dioxalate is reacted with N-ethylethylenediamine in an inert solvent (e. g., ethanol) at room temperature or under heating, to give a compound shown by the formula.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP18840881A JPS57118571A (en) | 1981-11-26 | 1981-11-26 | 1-ethyl-2,3-dioxopiperazine |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP18840881A JPS57118571A (en) | 1981-11-26 | 1981-11-26 | 1-ethyl-2,3-dioxopiperazine |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP1399276A Division JPS52106883A (en) | 1976-02-13 | 1976-02-13 | Novel penicillins and cephalosporins |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS57118571A true JPS57118571A (en) | 1982-07-23 |
Family
ID=16223124
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP18840881A Pending JPS57118571A (en) | 1981-11-26 | 1981-11-26 | 1-ethyl-2,3-dioxopiperazine |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57118571A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100542820B1 (en) * | 2002-09-17 | 2006-01-20 | 이재호 | Method of Preparing 1-Ethyl-2,3-Dioxopiperazine using oxalyl chloride |
US20100063273A1 (en) * | 2007-01-31 | 2010-03-11 | Toyama Chemical Co., Ltd | Novel crystal of piperacillin sodium |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS50148378A (en) * | 1974-05-09 | 1975-11-27 | Toyama Chemical Co Ltd | |
JPS50148380A (en) * | 1974-05-13 | 1975-11-27 | Toyama Chemical Co Ltd | |
JPS50151891A (en) * | 1974-05-31 | 1975-12-06 | Toyama Chemical Co Ltd |
-
1981
- 1981-11-26 JP JP18840881A patent/JPS57118571A/en active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS50148378A (en) * | 1974-05-09 | 1975-11-27 | Toyama Chemical Co Ltd | |
JPS50148380A (en) * | 1974-05-13 | 1975-11-27 | Toyama Chemical Co Ltd | |
JPS50151891A (en) * | 1974-05-31 | 1975-12-06 | Toyama Chemical Co Ltd |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100542820B1 (en) * | 2002-09-17 | 2006-01-20 | 이재호 | Method of Preparing 1-Ethyl-2,3-Dioxopiperazine using oxalyl chloride |
US20100063273A1 (en) * | 2007-01-31 | 2010-03-11 | Toyama Chemical Co., Ltd | Novel crystal of piperacillin sodium |
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