JPS57118571A - 1-ethyl-2,3-dioxopiperazine - Google Patents

1-ethyl-2,3-dioxopiperazine

Info

Publication number
JPS57118571A
JPS57118571A JP18840881A JP18840881A JPS57118571A JP S57118571 A JPS57118571 A JP S57118571A JP 18840881 A JP18840881 A JP 18840881A JP 18840881 A JP18840881 A JP 18840881A JP S57118571 A JPS57118571 A JP S57118571A
Authority
JP
Japan
Prior art keywords
ethyl
formula
acid
dioxopiperazine
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP18840881A
Other languages
Japanese (ja)
Inventor
Isamu Saikawa
Shuntaro Takano
Chosaku Yoshida
Okuta Takashima
Kaishu Momoi
Seietsu Kuroda
Miwako Komatsu
Takashi Yasuda
Hiroshi Kodama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toyama Chemical Co Ltd
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Priority to JP18840881A priority Critical patent/JPS57118571A/en
Publication of JPS57118571A publication Critical patent/JPS57118571A/en
Pending legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:1-Ethyl-2,3-dioxopiperazine shown by the formula.
USE: An intermediate for synthesizing a novel penicillin and a cephalosporin, namely 6-aminoacylaminopenicillanic acid and a compound obtaned by introducing 4-ethyl-2,3-dioxo-1-piperazinyl-carbonyl group to an amino group of 7-aminoacylaminocephalosporanic acid, which are capable of exhibiting effective antibacterial activity against even drug resistant bacteria, showing effective and safe effect in a living body.
PROCESS: A dioxalate is reacted with N-ethylethylenediamine in an inert solvent (e. g., ethanol) at room temperature or under heating, to give a compound shown by the formula.
COPYRIGHT: (C)1982,JPO&Japio
JP18840881A 1981-11-26 1981-11-26 1-ethyl-2,3-dioxopiperazine Pending JPS57118571A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP18840881A JPS57118571A (en) 1981-11-26 1981-11-26 1-ethyl-2,3-dioxopiperazine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP18840881A JPS57118571A (en) 1981-11-26 1981-11-26 1-ethyl-2,3-dioxopiperazine

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP1399276A Division JPS52106883A (en) 1976-02-13 1976-02-13 Novel penicillins and cephalosporins

Publications (1)

Publication Number Publication Date
JPS57118571A true JPS57118571A (en) 1982-07-23

Family

ID=16223124

Family Applications (1)

Application Number Title Priority Date Filing Date
JP18840881A Pending JPS57118571A (en) 1981-11-26 1981-11-26 1-ethyl-2,3-dioxopiperazine

Country Status (1)

Country Link
JP (1) JPS57118571A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100542820B1 (en) * 2002-09-17 2006-01-20 이재호 Method of Preparing 1-Ethyl-2,3-Dioxopiperazine using oxalyl chloride
US20100063273A1 (en) * 2007-01-31 2010-03-11 Toyama Chemical Co., Ltd Novel crystal of piperacillin sodium

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS50148378A (en) * 1974-05-09 1975-11-27 Toyama Chemical Co Ltd
JPS50148380A (en) * 1974-05-13 1975-11-27 Toyama Chemical Co Ltd
JPS50151891A (en) * 1974-05-31 1975-12-06 Toyama Chemical Co Ltd

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS50148378A (en) * 1974-05-09 1975-11-27 Toyama Chemical Co Ltd
JPS50148380A (en) * 1974-05-13 1975-11-27 Toyama Chemical Co Ltd
JPS50151891A (en) * 1974-05-31 1975-12-06 Toyama Chemical Co Ltd

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100542820B1 (en) * 2002-09-17 2006-01-20 이재호 Method of Preparing 1-Ethyl-2,3-Dioxopiperazine using oxalyl chloride
US20100063273A1 (en) * 2007-01-31 2010-03-11 Toyama Chemical Co., Ltd Novel crystal of piperacillin sodium

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