JPS57109798A - Antibiotic substance and its preparation - Google Patents

Antibiotic substance and its preparation

Info

Publication number
JPS57109798A
JPS57109798A JP18508780A JP18508780A JPS57109798A JP S57109798 A JPS57109798 A JP S57109798A JP 18508780 A JP18508780 A JP 18508780A JP 18508780 A JP18508780 A JP 18508780A JP S57109798 A JPS57109798 A JP S57109798A
Authority
JP
Japan
Prior art keywords
water
xii
forix
positive
readily soluble
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP18508780A
Other languages
Japanese (ja)
Inventor
Akio Iwasaki
Takeo Ideushi
Isamu Watanabe
Toshito Mori
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KOUWA KK
Kowa Co Ltd
Original Assignee
KOUWA KK
Kowa Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by KOUWA KK, Kowa Co Ltd filed Critical KOUWA KK
Priority to JP18508780A priority Critical patent/JPS57109798A/en
Priority to DE8181105357T priority patent/DE3162169D1/en
Priority to US06/281,898 priority patent/US4425430A/en
Priority to EP81105357A priority patent/EP0044477B1/en
Publication of JPS57109798A publication Critical patent/JPS57109798A/en
Priority to US06/541,291 priority patent/US4515942A/en
Pending legal-status Critical Current

Links

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  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:Antibiotic substances KA-6606IX,I, XI and XII (abbreviated toIX, X, XIand XII respectively), expressed by formulasIWIV, and having the following physico-chemical properties: Molecular formula : C14H30O4N4 forIX, X and XI; C13H27O7N3 for XII. Molecular weight : 318 for IX, X and XI and 337 for XII. Specific rotatory power : [α]D25 +86° forIX (C=1, water), +35° for X (C=0.3, water), +140° for XI(C=2, water) and +96 for XII, °(C=1, water). Solubility: IX, X and XI are readily soluble in water and methanol; XII is readily soluble in water; and all of them are insoluble in ethyl acetate and chloroform. All of them are positive to the ninhydrin and Rydon- Smith reactions.
USE: An antimicrobial agent against Gram-positive and Gram-negative bacteria.
PROCESS: A microoganism (FERM-P NO. 3912) belonging to the genus Saccharopolyspora is cultivated preferably under aerobic conditions at about 27°C for 2W 6 days, and the resultant culture is then treated according to the isolating and purifying method of water-soluble basic antibiotic substances.
COPYRIGHT: (C)1982,JPO&Japio
JP18508780A 1980-07-15 1980-12-27 Antibiotic substance and its preparation Pending JPS57109798A (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP18508780A JPS57109798A (en) 1980-12-27 1980-12-27 Antibiotic substance and its preparation
DE8181105357T DE3162169D1 (en) 1980-07-15 1981-07-09 Process for production of antibiotics, and novel antibiotics produced thereby
US06/281,898 US4425430A (en) 1980-07-15 1981-07-09 Process for production of antibiotics and novel antibiotics produced thereby
EP81105357A EP0044477B1 (en) 1980-07-15 1981-07-09 Process for production of antibiotics, and novel antibiotics produced thereby
US06/541,291 US4515942A (en) 1980-07-15 1983-10-11 Antibiotics KA-6606 XII, XIII, XV, XVI and XVII

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP18508780A JPS57109798A (en) 1980-12-27 1980-12-27 Antibiotic substance and its preparation

Publications (1)

Publication Number Publication Date
JPS57109798A true JPS57109798A (en) 1982-07-08

Family

ID=16164595

Family Applications (1)

Application Number Title Priority Date Filing Date
JP18508780A Pending JPS57109798A (en) 1980-07-15 1980-12-27 Antibiotic substance and its preparation

Country Status (1)

Country Link
JP (1) JPS57109798A (en)

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