JPS57109798A - Antibiotic substance and its preparation - Google Patents
Antibiotic substance and its preparationInfo
- Publication number
- JPS57109798A JPS57109798A JP18508780A JP18508780A JPS57109798A JP S57109798 A JPS57109798 A JP S57109798A JP 18508780 A JP18508780 A JP 18508780A JP 18508780 A JP18508780 A JP 18508780A JP S57109798 A JPS57109798 A JP S57109798A
- Authority
- JP
- Japan
- Prior art keywords
- water
- xii
- forix
- positive
- readily soluble
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:Antibiotic substances KA-6606IX,I, XI and XII (abbreviated toIX, X, XIand XII respectively), expressed by formulasIWIV, and having the following physico-chemical properties: Molecular formula : C14H30O4N4 forIX, X and XI; C13H27O7N3 for XII. Molecular weight : 318 for IX, X and XI and 337 for XII. Specific rotatory power : [α]D25 +86° forIX (C=1, water), +35° for X (C=0.3, water), +140° for XI(C=2, water) and +96 for XII, °(C=1, water). Solubility: IX, X and XI are readily soluble in water and methanol; XII is readily soluble in water; and all of them are insoluble in ethyl acetate and chloroform. All of them are positive to the ninhydrin and Rydon- Smith reactions.
USE: An antimicrobial agent against Gram-positive and Gram-negative bacteria.
PROCESS: A microoganism (FERM-P NO. 3912) belonging to the genus Saccharopolyspora is cultivated preferably under aerobic conditions at about 27°C for 2W 6 days, and the resultant culture is then treated according to the isolating and purifying method of water-soluble basic antibiotic substances.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP18508780A JPS57109798A (en) | 1980-12-27 | 1980-12-27 | Antibiotic substance and its preparation |
DE8181105357T DE3162169D1 (en) | 1980-07-15 | 1981-07-09 | Process for production of antibiotics, and novel antibiotics produced thereby |
US06/281,898 US4425430A (en) | 1980-07-15 | 1981-07-09 | Process for production of antibiotics and novel antibiotics produced thereby |
EP81105357A EP0044477B1 (en) | 1980-07-15 | 1981-07-09 | Process for production of antibiotics, and novel antibiotics produced thereby |
US06/541,291 US4515942A (en) | 1980-07-15 | 1983-10-11 | Antibiotics KA-6606 XII, XIII, XV, XVI and XVII |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP18508780A JPS57109798A (en) | 1980-12-27 | 1980-12-27 | Antibiotic substance and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS57109798A true JPS57109798A (en) | 1982-07-08 |
Family
ID=16164595
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP18508780A Pending JPS57109798A (en) | 1980-07-15 | 1980-12-27 | Antibiotic substance and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57109798A (en) |
-
1980
- 1980-12-27 JP JP18508780A patent/JPS57109798A/en active Pending
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