JPS57106684A - Syn-isomer of 7-substituted-3-cephem-4-carboxylic acid ester and its preparation - Google Patents

Syn-isomer of 7-substituted-3-cephem-4-carboxylic acid ester and its preparation

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Publication number
JPS57106684A
JPS57106684A JP18329980A JP18329980A JPS57106684A JP S57106684 A JPS57106684 A JP S57106684A JP 18329980 A JP18329980 A JP 18329980A JP 18329980 A JP18329980 A JP 18329980A JP S57106684 A JPS57106684 A JP S57106684A
Authority
JP
Japan
Prior art keywords
cephem
syn
isomer
substituted
carboxylic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP18329980A
Other languages
Japanese (ja)
Inventor
Takao Takatani
Hisashi Takasugi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Priority to JP18329980A priority Critical patent/JPS57106684A/en
Priority to DK554481A priority patent/DK554481A/en
Priority to IT8125581A priority patent/IT1142096B/en
Priority to ES507942A priority patent/ES8303422A1/en
Priority to FR8123457A priority patent/FR2496106B1/en
Priority to AT0536881A priority patent/AT376983B/en
Priority to NL8105658A priority patent/NL8105658A/en
Priority to GR66790A priority patent/GR76690B/el
Priority to GB8137724A priority patent/GB2092575B/en
Priority to DE19813149578 priority patent/DE3149578A1/en
Priority to SE8107520A priority patent/SE8107520L/en
Priority to US06/351,858 priority patent/US4477447A/en
Publication of JPS57106684A publication Critical patent/JPS57106684A/en
Pending legal-status Critical Current

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  • Cephalosporin Compounds (AREA)

Abstract

NEW MATERIAL:The compound of formulaI[R is phthalidylidene(lower)alkyl] or its salt.
EXAMPLE: 7-[ 2-( 2-Aminothiazol-4-yl )-2-methoxyiminoacetamido ]-3-cephem-4- carboxylic acid (syn-isomer) 3-phthalidylidene-ethyl ester.
USE: It has high antibacterial activity, and is useful as a preventive and remedy for bacteriosis.
PROCESS: The compound of formulaIis prepared by reacting the syn-isomer of 7- substituted-3-cephem-4-carboxyic acid of formula II or its salt with a phthalidylidene(lower)-alkylating agent (e.g. 3-phthalidylidenemethanol) in the presence of an organic or inorganic base such as Li, usually in a solvent such as water, acetone, acetonitrile, etc.
COPYRIGHT: (C)1982,JPO&Japio
JP18329980A 1980-12-15 1980-12-23 Syn-isomer of 7-substituted-3-cephem-4-carboxylic acid ester and its preparation Pending JPS57106684A (en)

Priority Applications (12)

Application Number Priority Date Filing Date Title
JP18329980A JPS57106684A (en) 1980-12-23 1980-12-23 Syn-isomer of 7-substituted-3-cephem-4-carboxylic acid ester and its preparation
DK554481A DK554481A (en) 1980-12-15 1981-12-14 METHOD OF PREPARING CEPHALOSPORANIC ACID DERIVATIVES
IT8125581A IT1142096B (en) 1980-12-15 1981-12-14 7-ACHYLAMINE CEPHALOSPORANIC ACID DERIVATIVES AND PROCEDURES FOR THEIR PREPARATION
ES507942A ES8303422A1 (en) 1980-12-15 1981-12-14 7-Acylaminocephalosporanic acid derivatives
FR8123457A FR2496106B1 (en) 1980-12-15 1981-12-15 7-ACYLAMINOCEPHALOSPORANIC ACID DERIVATIVES AND PROCESS FOR THEIR PREPARATION
AT0536881A AT376983B (en) 1980-12-15 1981-12-15 METHOD FOR PRODUCING NEW 7-ACYLAMINOCEPHALOSPORANIC ACID DERIVATIVES AND SALTS THEREOF
NL8105658A NL8105658A (en) 1980-12-15 1981-12-15 7-ACYLAMINOCEPHALOSPORANIC ACID DERIVATIVES AND METHODS OF PREPARATION THEREOF.
GR66790A GR76690B (en) 1980-12-15 1981-12-15
GB8137724A GB2092575B (en) 1980-12-15 1981-12-15 7-acylaminocephalosporanic acid derivatives
DE19813149578 DE3149578A1 (en) 1980-12-15 1981-12-15 7-ACYLAMINOCEPHALOSPORANIC ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS
SE8107520A SE8107520L (en) 1980-12-15 1981-12-15 7-ACYLAMINOCEPHALOSPORANIC ACID DERIVATIVES AND PROCEDURES FOR PREPARING THEREOF
US06/351,858 US4477447A (en) 1980-12-15 1982-02-24 7-Acylaminocephalosporanic acid derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP18329980A JPS57106684A (en) 1980-12-23 1980-12-23 Syn-isomer of 7-substituted-3-cephem-4-carboxylic acid ester and its preparation

Publications (1)

Publication Number Publication Date
JPS57106684A true JPS57106684A (en) 1982-07-02

Family

ID=16133232

Family Applications (1)

Application Number Title Priority Date Filing Date
JP18329980A Pending JPS57106684A (en) 1980-12-15 1980-12-23 Syn-isomer of 7-substituted-3-cephem-4-carboxylic acid ester and its preparation

Country Status (1)

Country Link
JP (1) JPS57106684A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5984890A (en) * 1982-11-05 1984-05-16 Hisayasu Ishimaru Cephalosporin compound for oral administration

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5984890A (en) * 1982-11-05 1984-05-16 Hisayasu Ishimaru Cephalosporin compound for oral administration

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