JPS57106684A - Syn-isomer of 7-substituted-3-cephem-4-carboxylic acid ester and its preparation - Google Patents
Syn-isomer of 7-substituted-3-cephem-4-carboxylic acid ester and its preparationInfo
- Publication number
- JPS57106684A JPS57106684A JP18329980A JP18329980A JPS57106684A JP S57106684 A JPS57106684 A JP S57106684A JP 18329980 A JP18329980 A JP 18329980A JP 18329980 A JP18329980 A JP 18329980A JP S57106684 A JPS57106684 A JP S57106684A
- Authority
- JP
- Japan
- Prior art keywords
- cephem
- syn
- isomer
- substituted
- carboxylic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Cephalosporin Compounds (AREA)
Abstract
NEW MATERIAL:The compound of formulaI[R is phthalidylidene(lower)alkyl] or its salt.
EXAMPLE: 7-[ 2-( 2-Aminothiazol-4-yl )-2-methoxyiminoacetamido ]-3-cephem-4- carboxylic acid (syn-isomer) 3-phthalidylidene-ethyl ester.
USE: It has high antibacterial activity, and is useful as a preventive and remedy for bacteriosis.
PROCESS: The compound of formulaIis prepared by reacting the syn-isomer of 7- substituted-3-cephem-4-carboxyic acid of formula II or its salt with a phthalidylidene(lower)-alkylating agent (e.g. 3-phthalidylidenemethanol) in the presence of an organic or inorganic base such as Li, usually in a solvent such as water, acetone, acetonitrile, etc.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (12)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP18329980A JPS57106684A (en) | 1980-12-23 | 1980-12-23 | Syn-isomer of 7-substituted-3-cephem-4-carboxylic acid ester and its preparation |
DK554481A DK554481A (en) | 1980-12-15 | 1981-12-14 | METHOD OF PREPARING CEPHALOSPORANIC ACID DERIVATIVES |
IT8125581A IT1142096B (en) | 1980-12-15 | 1981-12-14 | 7-ACHYLAMINE CEPHALOSPORANIC ACID DERIVATIVES AND PROCEDURES FOR THEIR PREPARATION |
ES507942A ES8303422A1 (en) | 1980-12-15 | 1981-12-14 | 7-Acylaminocephalosporanic acid derivatives |
FR8123457A FR2496106B1 (en) | 1980-12-15 | 1981-12-15 | 7-ACYLAMINOCEPHALOSPORANIC ACID DERIVATIVES AND PROCESS FOR THEIR PREPARATION |
AT0536881A AT376983B (en) | 1980-12-15 | 1981-12-15 | METHOD FOR PRODUCING NEW 7-ACYLAMINOCEPHALOSPORANIC ACID DERIVATIVES AND SALTS THEREOF |
NL8105658A NL8105658A (en) | 1980-12-15 | 1981-12-15 | 7-ACYLAMINOCEPHALOSPORANIC ACID DERIVATIVES AND METHODS OF PREPARATION THEREOF. |
GR66790A GR76690B (en) | 1980-12-15 | 1981-12-15 | |
GB8137724A GB2092575B (en) | 1980-12-15 | 1981-12-15 | 7-acylaminocephalosporanic acid derivatives |
DE19813149578 DE3149578A1 (en) | 1980-12-15 | 1981-12-15 | 7-ACYLAMINOCEPHALOSPORANIC ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS |
SE8107520A SE8107520L (en) | 1980-12-15 | 1981-12-15 | 7-ACYLAMINOCEPHALOSPORANIC ACID DERIVATIVES AND PROCEDURES FOR PREPARING THEREOF |
US06/351,858 US4477447A (en) | 1980-12-15 | 1982-02-24 | 7-Acylaminocephalosporanic acid derivatives |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP18329980A JPS57106684A (en) | 1980-12-23 | 1980-12-23 | Syn-isomer of 7-substituted-3-cephem-4-carboxylic acid ester and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS57106684A true JPS57106684A (en) | 1982-07-02 |
Family
ID=16133232
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP18329980A Pending JPS57106684A (en) | 1980-12-15 | 1980-12-23 | Syn-isomer of 7-substituted-3-cephem-4-carboxylic acid ester and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57106684A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5984890A (en) * | 1982-11-05 | 1984-05-16 | Hisayasu Ishimaru | Cephalosporin compound for oral administration |
-
1980
- 1980-12-23 JP JP18329980A patent/JPS57106684A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5984890A (en) * | 1982-11-05 | 1984-05-16 | Hisayasu Ishimaru | Cephalosporin compound for oral administration |
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