JPS57106645A - Preparation of 4-bromo-3-methylchrotonic acid ester - Google Patents
Preparation of 4-bromo-3-methylchrotonic acid esterInfo
- Publication number
- JPS57106645A JPS57106645A JP18277880A JP18277880A JPS57106645A JP S57106645 A JPS57106645 A JP S57106645A JP 18277880 A JP18277880 A JP 18277880A JP 18277880 A JP18277880 A JP 18277880A JP S57106645 A JPS57106645 A JP S57106645A
- Authority
- JP
- Japan
- Prior art keywords
- methylchrotonic
- acid ester
- bromo
- formula
- heptane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
PURPOSE: To obtain in high yield the titled compound useful as a raw material for synthesizing various kinds of compounds, by introducing bromine gas into a solution of 3-methylchrotonic acid in n-heptane under irradiation of light so that the ester is brominated.
CONSTITUTION: A 3-methylchrotonic acid ester shown by the formulaI(R is 1W 4C alkyl) is dissolved in n-heptane, bromine gas is introduced to the solution under irradiation of light, to give a 4-bromo-3-methylchrotonic acid ester shown by the formula II. The reaction temperature is preferably about the boiling point (98.35°C) of n-heptane. The compound shown by the formula II is obtained in high yield with a very small amount of formed 4-bromo-3-bromomethylchrotonic acid ester, 2,3-dibromo-3-methylchrotonic acid ester by-products. The compound shown by the formula II is useful as an intermediate for synthesizing a polyprenylcarboxylate, etc.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP18277880A JPS57106645A (en) | 1980-12-25 | 1980-12-25 | Preparation of 4-bromo-3-methylchrotonic acid ester |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP18277880A JPS57106645A (en) | 1980-12-25 | 1980-12-25 | Preparation of 4-bromo-3-methylchrotonic acid ester |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57106645A true JPS57106645A (en) | 1982-07-02 |
JPS643180B2 JPS643180B2 (en) | 1989-01-19 |
Family
ID=16124245
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP18277880A Granted JPS57106645A (en) | 1980-12-25 | 1980-12-25 | Preparation of 4-bromo-3-methylchrotonic acid ester |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57106645A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2014133116A1 (en) * | 2013-02-28 | 2014-09-04 | 公益財団法人相模中央化学研究所 | Method for producing 4-halosenecioic acid derivative |
-
1980
- 1980-12-25 JP JP18277880A patent/JPS57106645A/en active Granted
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2014133116A1 (en) * | 2013-02-28 | 2014-09-04 | 公益財団法人相模中央化学研究所 | Method for producing 4-halosenecioic acid derivative |
CN105102417A (en) * | 2013-02-28 | 2015-11-25 | 公益财团法人相模中央化学研究所 | Method for producing 4-halosenecioic acid derivative |
JPWO2014133116A1 (en) * | 2013-02-28 | 2017-02-02 | 公益財団法人相模中央化学研究所 | Process for producing 4-halosenecioic acid derivative |
Also Published As
Publication number | Publication date |
---|---|
JPS643180B2 (en) | 1989-01-19 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JPS57192392A (en) | Production of 3-alkoxymethylcephalosporin | |
JPS57106645A (en) | Preparation of 4-bromo-3-methylchrotonic acid ester | |
JPS5721341A (en) | Preparation of substituted acetic ester | |
JPS5695142A (en) | Preparation of aliphatic aldehyde | |
ES8307236A1 (en) | Process for the preparation of a furan derivative. | |
JPS5432480A (en) | Novel preparation of piperidine derivatives | |
JPS5756440A (en) | Preparation of 2-hydroxynaphthalene-3-carboxylic acid | |
JPS572268A (en) | Preparation of 5- p-chlorobenzoyl -1,4-dimethylpyrrole- 2-acetic acid | |
JPS57126427A (en) | Preparation of 1-substituted-azulene derivative | |
JPS55111468A (en) | Preparation of n-benzyl-tetrahydro isoquinoline derivative | |
JPS56113745A (en) | Preparation of bromonitroalcohol | |
JPS5562050A (en) | Preparation of substituted phenylacetohydroxamic acid | |
JPS5659727A (en) | Preparation of substituted phenol | |
JPS5432435A (en) | Preparation of tetrabromo terephthalic acid | |
JPS55127333A (en) | Preparation of substituted phenols | |
JPS56150092A (en) | Preparation of aroylaminopenicillanic ester sulfoxide | |
JPS51133249A (en) | A process for preparing alkyl-2,4- dichloro-nitrophenylcarbonates | |
JPS5522613A (en) | Preparation of 2-hydroxy-3-butenoic acid derivative | |
JPS55143936A (en) | Reparation of 3-pentenoic acid ester | |
JPS54148773A (en) | Preparation of phthalide | |
JPS5683464A (en) | Preparation of 2-alkoxyimino-3-keto-acid ester | |
JPS5655354A (en) | Preparation of alkylenediamine derivative | |
JPS5572139A (en) | Preparation of 4-allyloxy-3,5-disubstituted-phenylacetic acid | |
JPS5695153A (en) | Preparation of 3-isopropylamino-2-hydroxypropanol derivative | |
JPS53111026A (en) | Preparation of 5-alkoxy-4-hydroxyisophthalaldehyde |