JPS5671049A - Preparation of amino acid ester - Google Patents
Preparation of amino acid esterInfo
- Publication number
- JPS5671049A JPS5671049A JP14777779A JP14777779A JPS5671049A JP S5671049 A JPS5671049 A JP S5671049A JP 14777779 A JP14777779 A JP 14777779A JP 14777779 A JP14777779 A JP 14777779A JP S5671049 A JPS5671049 A JP S5671049A
- Authority
- JP
- Japan
- Prior art keywords
- cyanoformate
- formula
- compound
- bromocyanoacetate
- titanium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
PURPOSE: To obtain the titled compound useful as an intermediate for an additive of a medicine, agricultural chemical and high polymer in high yield, by reacting a cyanoformate with an active bromomethylene compound in the presence of a low-valent metal halide, and treating the reaction product with water, etc.
CONSTITUTION: A cyanoformate of formula I (R1 is 1W4C alkyl), e.g. methyl cyanoformate or butyl cyanoformate, is reacted with an active methylene compound, e.g. methyl bromocyanoacetate or propyl bromocyanoacetate, of formula II (R2 is 1W4C alkyl; Y is group of CN, etc.) in the presence of a metal halide of the formula MXn (M is tinhe or titanium; X is Cl or Br; n is 2 when M is tin, and 3 when M is titanium), and the reaction product is then treated with water or an acidic aqueous solution to give the titled compound of formula III without using a base.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14777779A JPS5671049A (en) | 1979-11-16 | 1979-11-16 | Preparation of amino acid ester |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14777779A JPS5671049A (en) | 1979-11-16 | 1979-11-16 | Preparation of amino acid ester |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5671049A true JPS5671049A (en) | 1981-06-13 |
JPS641462B2 JPS641462B2 (en) | 1989-01-11 |
Family
ID=15437941
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP14777779A Granted JPS5671049A (en) | 1979-11-16 | 1979-11-16 | Preparation of amino acid ester |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5671049A (en) |
-
1979
- 1979-11-16 JP JP14777779A patent/JPS5671049A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS641462B2 (en) | 1989-01-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JPS54148788A (en) | 1,2-disubstituted-4-halogenoimidazole-5-acetic acid derivative and its preparation | |
JPS5690031A (en) | Preparation of aromatic aldehyde | |
JPS57109787A (en) | Pyrazoloindazole derivative | |
JPS562929A (en) | Preparation of optically active cyclopentenolone | |
JPS5655359A (en) | Halogenated alpha-amino acid, and its preparation | |
JPS57192392A (en) | Production of 3-alkoxymethylcephalosporin | |
JPS5671049A (en) | Preparation of amino acid ester | |
JPS57203053A (en) | Preparation of cyanoacetic acid ester | |
JPS57203049A (en) | Preparation of amide derivative | |
JPS5671050A (en) | Preparation of amino acid ester | |
JPS5687541A (en) | Preparation of amino acid ester | |
JPS51115402A (en) | Process for preparation of alpha-amino acid | |
JPS5587734A (en) | Preparation of orthoester | |
JPS5687542A (en) | Preparation of amino acid ester | |
JPS5716892A (en) | Synthesis of n-trialkylsilylmethylurea | |
JPS56164129A (en) | Preparation of allyl alcohol | |
JPS5459223A (en) | Preparation of azo compounds | |
JPS5545608A (en) | Preparation of organosilver compound | |
JPS55162786A (en) | Glyoxylic acid derivative and its preparation | |
JPS5587769A (en) | Preparation of pyrroleacetic acid derivative | |
JPS56123972A (en) | Preparation of 1,3-dialkyl-4-benzoyl-5-hydroxypyrazole compound | |
JPS5770855A (en) | Preparation of methylene-bis-(4-phenylcarbamic acid ester) | |
JPS5553299A (en) | N2-substituted-phenyl-2,6-diaminonebularine | |
JPS57183732A (en) | 3-(4-chlorophenoxy)-4-fluorobenzaldehyde and its preparation | |
JPS5646889A (en) | Gold compound and its preparation |