JPS5668618A - Remedy for disease related to disorder of circulatory organ consisting essentially of kallikrein of human urine - Google Patents

Remedy for disease related to disorder of circulatory organ consisting essentially of kallikrein of human urine

Info

Publication number
JPS5668618A
JPS5668618A JP14362679A JP14362679A JPS5668618A JP S5668618 A JPS5668618 A JP S5668618A JP 14362679 A JP14362679 A JP 14362679A JP 14362679 A JP14362679 A JP 14362679A JP S5668618 A JPS5668618 A JP S5668618A
Authority
JP
Japan
Prior art keywords
kallikrein
human urine
remedy
consisting essentially
circulatory
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP14362679A
Other languages
Japanese (ja)
Inventor
Masaaki Yamada
Shigehiro Morichi
Eiji Sako
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Tanabe Pharma Corp
Original Assignee
Green Cross Corp Japan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Green Cross Corp Japan filed Critical Green Cross Corp Japan
Priority to JP14362679A priority Critical patent/JPS5668618A/en
Publication of JPS5668618A publication Critical patent/JPS5668618A/en
Pending legal-status Critical Current

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

PURPOSE: A remedy for disorders of circulatory organs having neither antigenicity nor side effects caused by immunological reactions, e.g., anaphylaxis, etc., consisting essentially of kallikrein of human urine.
CONSTITUTION: A remedy for disorders of circulatory organs consisting essentially of kallikrein of human urine. Kallikrein is a circulatory hormone, and effective against cerebral ischemia, dizziness, headache, etc. caused by hypertension, peripheral circulatory incompetence, cerebrobascular disorder, etc. Kallikrein is extracted from various organs of many animals, but it has side effects resulting from different kinds of protein. This agent is purified through isolation from the human urine, and has no antigenicity. The isolation is carried out practically by operation of adsorption and eluation using silica gel. Its dose is 0.1W5KE/kg for the improvement of cerebral blood stream, and 1W70KE/kg for the lowering of blood pressure.
COPYRIGHT: (C)1981,JPO&Japio
JP14362679A 1979-11-06 1979-11-06 Remedy for disease related to disorder of circulatory organ consisting essentially of kallikrein of human urine Pending JPS5668618A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP14362679A JPS5668618A (en) 1979-11-06 1979-11-06 Remedy for disease related to disorder of circulatory organ consisting essentially of kallikrein of human urine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP14362679A JPS5668618A (en) 1979-11-06 1979-11-06 Remedy for disease related to disorder of circulatory organ consisting essentially of kallikrein of human urine

Publications (1)

Publication Number Publication Date
JPS5668618A true JPS5668618A (en) 1981-06-09

Family

ID=15343120

Family Applications (1)

Application Number Title Priority Date Filing Date
JP14362679A Pending JPS5668618A (en) 1979-11-06 1979-11-06 Remedy for disease related to disorder of circulatory organ consisting essentially of kallikrein of human urine

Country Status (1)

Country Link
JP (1) JPS5668618A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0546533A2 (en) * 1991-12-10 1993-06-16 Sanwa Kagaku Kenkyusho Co., Ltd. Medical use of kininogenase
WO1999012576A3 (en) * 1997-09-11 1999-06-03 Musc Found For Res Dev Methods and compositions for treating cardiac and renal disorders with atrial natriuretic peptide and tissue kallikrein gene therapy

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS505515A (en) * 1973-05-17 1975-01-21

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS505515A (en) * 1973-05-17 1975-01-21

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0546533A2 (en) * 1991-12-10 1993-06-16 Sanwa Kagaku Kenkyusho Co., Ltd. Medical use of kininogenase
EP0546533A3 (en) * 1991-12-10 1994-03-30 Sanwa Kagaku Kenkyusho Co
WO1999012576A3 (en) * 1997-09-11 1999-06-03 Musc Found For Res Dev Methods and compositions for treating cardiac and renal disorders with atrial natriuretic peptide and tissue kallikrein gene therapy

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