JPS5665816A - Acetylsalicylate pharmaceutical for injection - Google Patents
Acetylsalicylate pharmaceutical for injectionInfo
- Publication number
- JPS5665816A JPS5665816A JP14163379A JP14163379A JPS5665816A JP S5665816 A JPS5665816 A JP S5665816A JP 14163379 A JP14163379 A JP 14163379A JP 14163379 A JP14163379 A JP 14163379A JP S5665816 A JPS5665816 A JP S5665816A
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical
- acetylsalicylate
- injection
- stabilizing agent
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PURPOSE: The titled pharmaceutical, useful as an analgesic, antipyretic and an antirheumatic agent or for treating arthritis, neuralgia and myalgia, and comprising a specific amount of aminoacetic acid as a stabilizing agent in a powder pharmaceutical containing an acetylsalicylate for injection.
CONSTITUTION: A powder pharmaceutical containing an acetylsalicylate obtained by reacting acetylsalicylic acid with a basic amino acid, e.g. DL-form lysine, is incorporated with 1W15%(w/w) or more aminoacetic acid as a stabilizing agent selected for preventing the discoloration to give an acetylsalicylate pharmaceutical for injection. The addition of CaCl2 as a stabilizing agent for improving the storage stability provides a stabler pharmaceutical.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14163379A JPS5665816A (en) | 1979-11-01 | 1979-11-01 | Acetylsalicylate pharmaceutical for injection |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14163379A JPS5665816A (en) | 1979-11-01 | 1979-11-01 | Acetylsalicylate pharmaceutical for injection |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5665816A true JPS5665816A (en) | 1981-06-03 |
JPS6121529B2 JPS6121529B2 (en) | 1986-05-27 |
Family
ID=15296572
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP14163379A Granted JPS5665816A (en) | 1979-11-01 | 1979-11-01 | Acetylsalicylate pharmaceutical for injection |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5665816A (en) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63307824A (en) * | 1987-06-09 | 1988-12-15 | Teisan Seiyaku Kk | Stabilized powdery preparation for injection |
WO1999018959A1 (en) * | 1997-10-14 | 1999-04-22 | Eisai Co., Ltd. | Pharmaceutical formulation comprising glycine as a stabilizer |
WO2006128600A3 (en) * | 2005-06-02 | 2007-04-26 | Bayer Healthcare Ag | Stabile active ingredient complex of salts of the o-acetylsalicylic acid with basic amino acids and glycine |
US7230014B1 (en) | 1997-10-14 | 2007-06-12 | Eisai Co., Ltd. | Pharmaceutical formulation comprising glycine as a stabilizer |
JP2008114896A (en) * | 2006-11-07 | 2008-05-22 | Kyocera Mita Corp | Auxiliary plate for taking out packed product |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH01112835U (en) * | 1988-01-26 | 1989-07-28 |
-
1979
- 1979-11-01 JP JP14163379A patent/JPS5665816A/en active Granted
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63307824A (en) * | 1987-06-09 | 1988-12-15 | Teisan Seiyaku Kk | Stabilized powdery preparation for injection |
WO1999018959A1 (en) * | 1997-10-14 | 1999-04-22 | Eisai Co., Ltd. | Pharmaceutical formulation comprising glycine as a stabilizer |
US7230014B1 (en) | 1997-10-14 | 2007-06-12 | Eisai Co., Ltd. | Pharmaceutical formulation comprising glycine as a stabilizer |
WO2006128600A3 (en) * | 2005-06-02 | 2007-04-26 | Bayer Healthcare Ag | Stabile active ingredient complex of salts of the o-acetylsalicylic acid with basic amino acids and glycine |
JP2008542316A (en) * | 2005-06-02 | 2008-11-27 | バイエル・ヘルスケア・アクチェンゲゼルシャフト | Salts of o-acetylsalicylic acid with basic amino acids and stable active compound complexes of glycine |
AU2006254429B2 (en) * | 2005-06-02 | 2011-11-10 | Bayer Intellectual Property Gmbh | Stabile active ingredient complex of salts of the o-acetylsalicylic acid with basic amino acids and glycine |
US8063243B2 (en) | 2005-06-02 | 2011-11-22 | Bayer Pharma Aktiengesellschaft | Stable active compound complex of salts of o-acetylsalicylic acid with basic amino acids and glycine |
JP2008114896A (en) * | 2006-11-07 | 2008-05-22 | Kyocera Mita Corp | Auxiliary plate for taking out packed product |
Also Published As
Publication number | Publication date |
---|---|
JPS6121529B2 (en) | 1986-05-27 |
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